Full Text Journal Articles by
Author Vincent Vander Poorten

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High-grade Transformation/Dedifferentiation in Salivary Gland Carcinomas: Occurrence Across Subtypes and Clinical Significance.

Alena Skalova, Ilmo Leivo, Henrik Hellquist, Abbas Agaimy, Roderick H W Simpson, Göran Stenman, Vincent Vander Poorten, Justin A Bishop, Alessandro Franchi, Juan C Hernandez-Prera, David Slouka, Stefan M Willems, Kerry D Olsen, Alfio Ferlito,

High-grade transformation (HGT) or dedifferentiation has been described in a variety of salivary gland carcinomas, including acinic cell carcinoma, secretory carcinoma, adenoid cystic carcinoma, epithelial-myoepithelial carcinoma, polymorphous adenocarcinoma, low-grade mucoepidermoid carcinoma, and hyalinizing clear cell carcinoma. High-grade (HG) transformed tumors are composed of a conventional low-grade component characterized by specific ... Read more >>

Adv Anat Pathol (Advances in anatomic pathology)
[2021, 28(3):107-118]

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Current indications for adjuvant treatment following transoral laser microsurgery of early intermediate laryngeal cancer.

Vincent Vander Poorten, Jeroen Meulemans, Charlotte Van Lierde, Sandra Nuyts, Pierre Delaere,

<h4>Purpose of review</h4>This review summarizes the information in the literature on the indications for adjuvant therapy after transoral laser microsurgery (TLM) for early/intermediate stage laryngeal cancer.<h4>Recent findings</h4>A high rate of 'nonevaluable' margins after TLM significantly complicates decision-making concerning adjuvant therapy. However, consensus grows that second-look TLM in patients with multiple ... Read more >>

Curr Opin Otolaryngol Head Neck Surg (Current opinion in otolaryngology & head and neck surgery)
[2021, 29(2):79-85]

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Photodynamic Therapy as an Alternative Therapeutic Tool in Functionally Inoperable Oral and Oropharyngeal Carcinoma: A Single Tertiary Center Retrospective Cohort Analysis.

Arnaud Lambert, Lotte Nees, Sandra Nuyts, Paul Clement, Jeroen Meulemans, Pierre Delaere, Vincent Vander Poorten,

<b>Background:</b> Head and neck cancer is typically treated with surgery, radiotherapy, chemoradiation, or a combination of these treatments. This study aims to retrospectively analyse oncological outcomes, adverse events and toxicity of treatment with temoporfin-mediated photodynamic therapy at a single tertiary referral center. More specifically, in a selected group of patients ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:626394]

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A Method Based on 3D Shape Analysis Towards the Design of Flexible Instruments for Endoscopic Maxillary Sinus Surgery.

Julie Legrand, Kenan Niu, Zhen Qian, Kathleen Denis, Vincent Vander Poorten, Laura Van Gerven, Emmanuel Vander Poorten,

The emergence of steerable flexible instruments has widened the uptake of minimally invasive surgical techniques. In sinus surgery, such flexible instruments could enable the access to difficult-to-reach anatomical areas. However, design-oriented metrics, essential for the development of steerable flexible instruments for maxillary sinus surgery, are still lacking. This paper proposes ... Read more >>

Ann Biomed Eng (Annals of biomedical engineering)
[2021, :]

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Pleomorphic Adenoma: The Great Mimicker of Malignancy.

Juan C Hernandez-Prera, Alena Skálová, Alessandro Franchi, Alessandra Rinaldo, Vincent Vander Poorten, Peter Zbären, Alfio Ferlito, Bruce M Wenig,

Pleomorphic adenoma is the most common salivary gland neoplasm and its diagnosis is straightforward in majority of cases. However; not infrequently PA exhibits unusual and uncommon histological findings that can erroneously be confused with malignancy. The diagnostic difficulties of PA arise from its ability of mimic invasion, show atypical or ... Read more >>

Histopathology (Histopathology)
[2020, :]

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Frozen section in thyroid gland follicular neoplasms: It's high time to abandon it!

Alvaro Sanabria, Mark Zafereo, Lester D R Thompson, Juan C Hernandez-Prera, Luiz P Kowalski, Iain J Nixon, Ashok Shaha, Juan P Rodrigo, Antti Mäkitie, Vincent Vander Poorten, Carlos Suarez, Peter Zbären, Alessandra Rinaldo, Alfio Ferlito,

Thyroid nodules are a very common clinical condition. The 2015 American Thyroid Association (ATA) guidelines recommend surgical excision for Bethesda IV nodules. The use of intraoperative frozen section (FS) has been recommended as a strategy to tailor the extent of the initial surgery. We critically evaluated the literature that discusses ... Read more >>

Surg Oncol (Surgical oncology)
[2021, 36:76-81]

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Prognostic role of intraparotid lymph node metastasis in primary parotid cancer: Systematic review.

Orlando Guntinas-Lichius, Jovanna Thielker, K Thomas Robbins, Kerry D Olsen, Ashok R Shaha, Antti A Mäkitie, Remco de Bree, Vincent Vander Poorten, Miquel Quer, Alessandra Rinaldo, Luiz Paulo Kowalski, Juan Pablo Rodrigo, Marc Hamoir, Alfio Ferlito,

<h4>Background</h4>The prognostic importance of intraparotid lymph node metastasis (P+) in patients with primary parotid gland carcinoma is unclear.<h4>Methods</h4>Nineteen retrospective and noncomparative cohort studies, published between 1992 and 2020, met the inclusion criteria and included 2202 patients for this systematic review.<h4>Results</h4>The pooled prevalence of the P in adult patients in the ... Read more >>

Head Neck (Head & neck)
[2021, 43(3):997-1008]

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Immediate Intraoperative Repair of the Recurrent Laryngeal Nerve in Thyroid Surgery.

Ricard Simó, Iain J Nixon, Aleix Rovira, Vincent Vander Poorten, Alvaro Sanabria, Mark Zafereo, Dana M Hartl, Luiz P Kowalski, Gregory W Randolph, Dipti Kamani, Ashok R Shaha, Jatin Shah, Jean-Paul Marie, Alessandra Rinaldo, Alfio Ferlito,

<h4>Objectives</h4>Recurrent laryngeal nerve (RLN) injury is a recognized risk during thyroid and parathyroid surgery and can result in significant morbidity. The aim of this review paper is to consider the optimal approach to the immediate intraoperative repair of the RLN during thyroid surgery.<h4>Methods</h4>A PubMed literature search was performed from inception ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Management of the Neck in Well-Differentiated Thyroid Cancer.

Panagiotis Asimakopoulos, Ashok R Shaha, Iain J Nixon, Jatin P Shah, Gregory W Randolph, Peter Angelos, Mark E Zafereo, Luiz P Kowalski, Dana M Hartl, Kerry D Olsen, Juan P Rodrigo, Vincent Vander Poorten, Antti A Mäkitie, Alvaro Sanabria, Carlos Suárez, Miquel Quer, Francisco J Civantos, K Thomas Robbins, Orlando Guntinas-Lichius, Marc Hamoir, Alessandra Rinaldo, Alfio Ferlito,

<h4>Purpose of review</h4>In this narrative review, we discuss the indications for elective and therapeutic neck dissections and the postoperative surveillance and treatment options for recurrent nodal disease in patients with well-differentiated thyroid cancer.<h4>Recent findings</h4>Increased availability of advanced imaging modalities has led to an increased detection rate of previously occult nodal ... Read more >>

Curr Oncol Rep (Current oncology reports)
[2020, 23(1):1]

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The impact of nodal status in major salivary gland carcinoma: A multicenter experience and proposal of a novel N-classification.

Davide Lombardi, Michele Tomasoni, Alberto Paderno, Davide Mattavelli, Marco Ferrari, Simonetta Battocchio, Francesco Missale, Francesco Mazzola, Giorgio Peretti, Davide Mocellin, Daniele Borsetto, Jonathan M Fussey, Paul Nankivell, Nikoleta Skalidi, Mario Bussi, Leone Giordano, Andrea Galli, Gianluigi Arrigoni, Elena Raffetti, Paul Pracy, Vincent Vander Poorten, Piero Nicolai,

<h4>Objectives</h4>Despite differences in oncological behavior, the 8th edition of AJCC TNM staging currently proposes the same N-classification for major salivary glands (MSG) carcinoma and squamous cell carcinoma of the upper aerodigestive tract. The present study aims to investigate a more reliable definition of N-categories for MSG carcinoma.<h4>Materials and methods</h4>A retrospective ... Read more >>

Oral Oncol (Oral oncology)
[2021, 112:105076]

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The Value of Virtual Chromoendoscopy in the Workup of Patients with Head and Neck Squamous Cell Carcinoma.

Charlotte Van Lierde, Brecht Gyselinck, Jeroen Meulemans, Raf Bisschops, Pierre Delaere, Vincent Vander Poorten,

<h4>Purpose of review</h4>Second primary tumors (SPTs) significantly increase the mortality in patients with head and neck squamous cell carcinomas (HNSCCs). Virtual chromoendoscopy (VCE) could complement or replace lugol chromoendoscopy (LCE) for early esophageal second primary tumor (ESPT) detection. An overview of the existing techniques and their diagnostic performance in early ... Read more >>

Curr Oncol Rep (Current oncology reports)
[2020, 22(12):121]

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Author's response to the letter of the editor regarding the "Review of surgical techniques and guide for decision making in the treatment of benign parotid tumors".

Georgios Psychogios, Christopher Bohr, Jannis Constantinidis, Martin Canis, Vincent Vander Poorten, Jan Plzak, Andreas Knopf, Christian Betz, Orlando Guntinas-Lichius, Johannes Zenk,

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2020, 277(12):3539-3540]

Cited: 1 time

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Functional Outcomes and Complications After Salvage Total Laryngectomy for Residual, Recurrent, and Second Primary Squamous Cell Carcinoma of the Larynx and Hypopharynx: A Multicenter Retrospective Cohort Study.

Jeroen Meulemans, Hannelore Demarsin, Jens Debacker, Gaël Batailde, Tillo Mennes, Annouschka Laenen, Ann Goeleven, Peter Neyt, Christophe Vanclooster, Tom Vauterin, Pierre Delaere, Wouter Huvenne, Vincent Vander Poorten,

<b>Background/Purpose:</b> We analyzed complications and functional outcomes and aimed at identifying prognostic factors for functional outcomes and complications in patients who underwent salvage total laryngectomy (STL) for residual, recurrent, and second primary squamous cell carcinoma (SCC) of the larynx and hypopharynx after initial (chemo)radiation. <b>Methods:</b> Retrospective cohort study of patients ... Read more >>

Front Oncol (Frontiers in oncology)
[2020, 10:1390]

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Correction to: Review of surgical techniques and guide for decision making in the treatment of benign parotid tumors.

Georgios Psychogios, Christopher Bohr, Jannis Constantinidis, Martin Canis, Vincent Vander Poorten, Jan Plzak, Andreas Knopf, Christian Betz, Orlando Guntinas-Lichius, Johannes Zenk,

In the original publication of the article, one of the author's name was published incorrectly as "Christopher Betz". The correct name is Christian Betz. ... Read more >>

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2020, :]

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ASO Author Reflections: Salvage Total Laryngectomy, the Last Resort for Patients with Residual, Recurrent or Second Primary Laryngeal and Hypopharyngeal Cancer in Times of Nonsurgical Organ Preserving Treatment Strategies.

Jens Debacker, Jeroen Meulemans, Wouter Huvenne, Vincent Vander Poorten,

Ann Surg Oncol (Annals of surgical oncology)
[2020, 27(Suppl 3):905-906]

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Validated Prognostic Nomograms for Patients With Parotid Carcinoma Predicting 2- and 5-Year Tumor Recurrence-Free Interval Probability.

Sam Peeperkorn, Jeroen Meulemans, Charlotte Van Lierde, Annouschka Laenen, Matthijs H Valstar, A J M Balm, Pierre Delaere, Vincent Vander Poorten,

<b>Introduction:</b> Salivary gland malignancies are rare tumors with a heterogenous histological and clinical appearance. Previously, we identified multiple prognostic factors in patients with parotid cancer and developed prognostic indices which have repeatedly been validated internationally, demonstrating their general applicability and lasting relevance. Recently, nomograms gained popularity as a prognostic tool. ... Read more >>

Front Oncol (Frontiers in oncology)
[2020, 10:1535]

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Transoral Laser Microsurgery (TLM) for Glottic Cancer: Prospective Assessment of a New Pathology Workup Protocol.

Jeroen Meulemans, Esther Hauben, Samuel Peeperkorn, Sandra Nuyts, Pierre Delaere, Vincent Vander Poorten,

<b>Background/Purpose:</b> The value of margin status after TLM for glottic cancer is debatable, due to difficulties in specimen orientation and margin analysis. Purpose of this study was the prospective evaluation of feasibility of a new standardized technique of oriented fixation of the TLM specimen and identification of the added value ... Read more >>

Front Surg (Frontiers in surgery)
[2020, 7:56]

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Oncologic Outcomes After Salvage Laryngectomy for Squamous Cell Carcinoma of the Larynx and Hypopharynx: A Multicenter Retrospective Cohort Study.

Jeroen Meulemans, Jens Debacker, Hannelore Demarsin, Christophe Vanclooster, Peter Neyt, Tillo Mennes, Tom Vauterin, Wouter Huvenne, Annouschka Laenen, Pierre Delaere, Vincent Vander Poorten,

<h4>Objective</h4>We aimed to analyze oncologic outcomes and identify patterns of failure and negative prognostic factors in patients who underwent salvage total laryngectomy (STL) for residual, recurrent, and second primary squamous cell carcinoma (SCC) of the larynx and hypopharynx.<h4>Methods</h4>This was a retrospective cohort study of patients who underwent STL in four ... Read more >>

Ann Surg Oncol (Annals of surgical oncology)
[2021, 28(3):1751-1761]

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Review of surgical techniques and guide for decision making in the treatment of benign parotid tumors.

Georgios Psychogios, Christopher Bohr, Jannis Constantinidis, Martin Canis, Vincent Vander Poorten, Jan Plzak, Andreas Knopf, Christian Betz, Orlando Guntinas-Lichius, Johannes Zenk,

<h4>Purpose</h4>Surgical treatment of benign parotid tumors has developed in the direction of less invasive procedures in recent years and has raised great debate about the best surgical approach. Aim of this article is to analyse anatomical and other factors that are important in selection of the appropriate surgical technique in ... Read more >>

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2021, 278(1):15-29]

Cited: 1 time

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Case for staged thyroidectomy.

Ohad Ronen, K Thomas Robbins, Kerry D Olsen, Ashok R Shaha, Gregory W Randolph, Iain J Nixon, Mark E Zafereo, Dana M Hartl, Luiz P Kowalski, Juan P Rodrigo, Andrés Coca-Pelaz, Antti A Mäkitie, Vincent Vander Poorten, Alvaro Sanabria, Peter Angelos, Alessandra Rinaldo, Alfio Ferlito,

Recent modifications in the management of well-differentiated thyroid cancer have resulted in significant alterations in clinical approach. Utilizing a series of preoperative and postoperative risk factors involving both the patient and the disease pathology, we offer the term "staged thyroidectomy" to help organize these risk factors for patients and the ... Read more >>

Head Neck (Head & neck)
[2020, 42(10):3061-3071]

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A Comprehensive Update on Intestinal- and Non-Intestinal-Type Adenocarcinomas.

Vincent Vander Poorten, Mark Jorissen,

This review of sinonasal adenocarcinoma, both intestinal and non-intestinal type, aims at providing a comprehensive overview of etiological factors, diagnostic workup, histological subtypes, advances in molecular characterization and the genetic basis, current optimal treatment strategies, resulting oncological outcome, and prognostic factors modifying the final treatment results. The current treatment of ... Read more >>

Adv Otorhinolaryngol (Advances in oto-rhino-laryngology)
[2020, 84:137-153]

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Prognostic nomogram in patients with metastatic adenoid cystic carcinoma of the salivary glands.

Stefano Cavalieri, Luigi Mariani, Vincent Vander Poorten, Laure Van Breda, Maria C Cau, Salvatore Lo Vullo, Salvatore Alfieri, Carlo Resteghini, Cristiana Bergamini, Ester Orlandi, Giuseppina Calareso, Paul Clement, Esther Hauben, Francesca Platini, Paolo Bossi, Lisa Licitra, Laura D Locati,

<h4>Background</h4>Distant metastases in adenoid cystic carcinoma (ACC) are common. There is no consensus on the management of metastatic disease because no therapeutic approach has demonstrated improvement in overall survival (OS) and because of prolonged life expectancy. The aim of this study is to build and validate a prognostic nomogram for metastatic ... Read more >>

Eur J Cancer (European journal of cancer (Oxford, England : 1990))
[2020, 136:35-42]

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Multifocality in papillary thyroid carcinoma-An unresolved controversy.

Ashok R Shaha, Vincent Vander Poorten, R Michael Tuttle,

Eur J Surg Oncol (European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology)
[2020, 46(10 Pt A):1777-1778]

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Papillary Thyroid Cancer-Aggressive Variants and Impact on Management: A Narrative Review.

Andrés Coca-Pelaz, Jatin P Shah, Juan C Hernandez-Prera, Ronald A Ghossein, Juan P Rodrigo, Dana M Hartl, Kerry D Olsen, Ashok R Shaha, Mark Zafereo, Carlos Suarez, Iain J Nixon, Gregory W Randolph, Antti A Mäkitie, Luiz P Kowalski, Vincent Vander Poorten, Alvaro Sanabria, Orlando Guntinas-Lichius, Ricard Simo, Peter Zbären, Peter Angelos, Avi Khafif, Alessandra Rinaldo, Alfio Ferlito,

<h4>Introduction</h4>Aggressive variants of papillary thyroid cancer (PTC) have been described with increasing frequency. These variants include diffuse sclerosing variant, tall cell variant, columnar cell variant, solid variant, and hobnail variant.<h4>Methods</h4>We have performed a review of the more aggressive variants of PTC with respect to main characteristics, histological and molecular features, ... Read more >>

Adv Ther (Advances in therapy)
[2020, 37(7):3112-3128]

Cited: 2 times

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The Milan system for reporting salivary gland cytopathology: Single center experience with cell blocks.

Marie Behaeghe, Vincent Vander Poorten, Robert Hermans, Constantinus Politis, Birgit Weynand, Esther Hauben,

<h4>Background</h4>Salivary gland fine needle aspiration (FNA) has a well-established role in the evaluation of salivary gland lesions. The Milan system for reporting salivary gland cytopathology (MSRSGC) was developed in 2018 to accomplish a standardized reporting across institutions. This classification is predominantly based on the use of direct smears. This single ... Read more >>

Diagn Cytopathol (Diagnostic cytopathology)
[2020, 48(11):972-978]

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