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Author Vildan Kaya

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Reoperation does not provide a survival advantage in patients with recurrent Glioblastoma treated with irinotecan/bevacizumab treatment.

Ozlem Nuray Sever, Kadir Oktay, Ebru Güzel, Vildan Kaya, Aslan Güzel, Mustafa Yıldırım,

<h4>Background</h4>Treatment options for recurrent glioblastoma (GBM) have limited efficacy. Although reoperation is useful for both the confirmation of the diagnosis of recurring disease and the relief of the symptoms, its effect on survival is unknown. The aim of this study was to evaulate the impact of second surgery in recurrent ... Read more >>

Indian J Cancer (Indian journal of cancer)
[2021, 58(1):91-95]

Cited: 0 times

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A novel diagnostic tool for the detection of bladder cancer: Measurement of urinary high mobility group box-1.

Necla Benlier, Mehmet Solakhan, Zeliha Yıldırım, Vildan Kaya, Ömer Aydın Yıldırım, Nuri Orhan, Hülya Çiçek, Mustafa Yıldırım,

<h4>Objective</h4>We aimed to investigate the diagnostic value of urinary High Mobility Group Box-1 (HMGB1) level as a noninvasive tool that can be potentially used for diagnosis and during follow-up in patients with bladder cancer patients.<h4>Method</h4>The study was conducted in a total of 121 participants including 61 patients diagnosed with primary ... Read more >>

Urol Oncol (Urologic oncology)
[2020, 38(8):685.e11-685.e16]

Cited: 0 times

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Effectiveness of Platinum-Based Treatment for Triple Negative Metastatic Breast Cancer: a Meta-Analysis

Vildan Kaya, Mustafa Yildirim, Gozde Yazici, Seyda Gunduz, Hakan Bozcuk, Semra Paydas,

Background: Triple-negative breast cancer (TNBC) is a sub-group of breast cancers with a particularly poor prognosis. The results of studies investigating the role of platinum-based chemotherapy (PBC) in metastatic TNBC (mTNBC) have been conflicting. In this meta-analysis, our aim was to assess the effectiveness of PBCs for mTNBCs. Methods: The PubMed, Cochrane Controlled ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2018, 19(5):1169-1173]

Cited: 5 times

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Prognostic Significance of Indicators of Systemic Inflammatory Responses in Glioblastoma Patients

Vildan Kaya, Mustafa Yıldırım, Gözde Yazıcı, Ayşen Yeşim Yalçın, Nuri Orhan, Aslan Güzel,

Background: High-grade gliomas, with glioblastomas as the most frequently observed histologic subtype, are the most common primary brain tumours in adults. It is considered that inflammatory responses play a major role in malignancies, including tumour progression. This study aimed to determine the prognostic significance of the neutrophil to lymphocyte ratio (NLR) and the ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2017, 18(12):3287-3291]

Cited: 5 times

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Expression of claudin 1, 4 and 7 in thyroid neoplasms.

Dinç Süren, Mustafa Yildirim, Alper Sayiner, Arsenal Sezgin Alikanoğlu, Irem Atalay, Umut Riza Gündüz, Vildan Kaya, Şeyda Gündüz, Mehmet Tahir Oruç, Cem Sezer,

The distinction of thyroid carcinoma from benign thyroid neoplasm, as well as the subtyping of papillary carcinoma (PC) and follicular carcinoma (FC), may be performed histopathologically in the majority of cases. However, in certain cases, it is difficult to histopathologically distinguish between PC and FC, as well as follicular adenoma ... Read more >>

Oncol Lett (Oncology letters)
[2017, 13(5):3722-3726]

Cited: 5 times

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Effects of pacifier use on transition to full breastfeeding and sucking skills in preterm infants: a randomised controlled trial.

Vildan Kaya, Aynur Aytekin,

<h4>Aims and objectives</h4>To determine the effects of pacifier use on transition to full breastfeeding and sucking skills in preterm infants.<h4>Background</h4>Feeding problems in preterm infants cause delays in hospital discharge, extend mother-infant reunification and increase medical cost. Nutritive sucking skills of preterm infants may develop by improving non-nutritive sucking skills and ... Read more >>

J Clin Nurs (Journal of clinical nursing)
[2017, 26(13-14):2055-2063]

Cited: 5 times

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Effects of Definitive Chemoradiotherapy on Respiratory Function Tests and Quality of Life Scores During Treatment of Lung Cancer.

Evrim Duman, Mustafa Yildirim, Vildan Kaya, Duriye Ozturk, Aysun Inal, Zeynep Akarsu, Seyda Gunduz, Mustafa Yildiz,

<h4>Background</h4>Chemoradiotherapy is an important treatment modality for lung cancers. The aim of this study was to investigate alterations in, as well as the interrelationship between, lung function and quality of life of patients receiving chemoradiotherapy due to locally advanced non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2015, 16(15):6779-6782]

Cited: 1 time

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Expression patterns of claudins 1, 4, and 7 and their prognostic significance in nasopharyngeal carcinoma.

Dinc Suren, Mustafa Yildirim, Vildan Kaya, Ruksan Elal, Omer Tarik Selcuk, Ustun Osma, Mustafa Yildiz, Seyda Gunduz, Cem Sezer,

<h4>Purpose</h4>Tight junction (TJ) proteins in the cells organize paracellular permeability, and they have a critical role in apical cell-to-cell adhesion and epithelial polarity. In our study, the expression patterns of claudins 1, 4, and 7 and their relationship with prognosis were determined in patients with nasopharyngeal carcinoma.<h4>Methods</h4>Claudins 1, 4, and ... Read more >>

J BUON (Journal of B.U.ON. : official journal of the Balkan Union of Oncology)
[2015, 20(1):212-217]

Cited: 8 times

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The role of gender in patients with diffuse large B cell lymphoma treated with rituximab-containing regimens: a meta-analysis.

Mustafa Yıldırım, Vildan Kaya, Özlem Demirpençe, Semra Paydaş,

INTRODUCTION:Diffuse large B cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL). Although gender has not been included in prognostic systems, male gender has been found as a bad prognostic indicator in Hodgkin lymphoma, follicular lymphoma and chronic lymphocytic leukemia. The relationship between gender and prognosis is ... Read more >>

Arch Med Sci (Archives of medical science : AMS)
[2015, 11(4):708-714]

Cited: 6 times

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The clinical and pathological features of 133 colorectal cancer patients with brain metastasis: a multicenter retrospective analysis of the Gastrointestinal Tumors Working Committee of the Turkish Oncology Group (TOG).

Ozgur Tanriverdi, Esra Kaytan-Saglam, Sukran Ulger, Ibrahim Vedat Bayoglu, Ibrahim Turker, Turkan Ozturk-Topcu, Suna Cokmert, Serdar Turhal, Esin Oktay, Bulent Karabulut, Diclehan Kilic, Yuksel Kucukzeybek, Berna Oksuzoglu, Nezih Meydan, Vildan Kaya, Tulay Akman, Kamuran Ibis, Mert Saynak, Cenk Ahmet Sen, Ozlem Uysal-Sonmez, Kezban Nur Pilancı, Gokhan Demir, Sezer Saglam, Muharrem Kocar, Serkan Menekse, Gamze Goksel, Burcu Yapar-Taskoylu, Arzu Yaren, Ummugul Uyeturk, Nilufer Avci, Bengu Denizli, Esra Ilis-Temiz,

Brain metastasis in colorectal cancer is highly rare. In the present study, we aimed to determine the frequency of brain metastasis in colorectal cancer patients and to establish prognostic characteristics of colorectal cancer patients with brain metastasis. In this cross-sectional study, the medical files of colorectal cancer patients with brain ... Read more >>

Med Oncol (Medical oncology (Northwood, London, England))
[2014, 31(9):152]

Cited: 18 times

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Mandible bone metastases secondary to pulmonary adenocarcinoma.

Nigar Dirican, Sedat Gunes, Yeliz Karakaya, Vildan Kaya, Sureyya Cerci, Ahmet Dirican,

<h4>Objective</h4>Metastatic tumors of the mandible are rare and usually present clinically as growths. The prognosis of lung cancer patients with bone metastases is poor.<h4>Case report</h4>This article shows a metastasis from adenocarcinoma of the lung affecting the mandible of a 75-year-old female patient where the metastatic lesion was detected before primary ... Read more >>

Med Arch (Medical archives (Sarajevo, Bosnia and Herzegovina))
[2014, 68(5):356-358]

Cited: 0 times

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Loss of tight junction proteins (Claudin 1, 4, and 7) correlates with aggressive behavior in colorectal carcinoma.

Dinç Süren, Mustafa Yıldırım, Vildan Kaya, Arsenal Sezgin Alikanoğlu, Nurullah Bülbüller, Mustafa Yıldız, Cem Sezer,

<h4>Background</h4>Tight junction proteins in the cell organize paracellular permeability and they play a critical role in apical cell-to-cell adhesion and epithelial polarity. Claudins are major integral membrane proteins of tight junctions, especially Claudin 1, 4, and 7, which are known as the impermeability Claudins. In this study, we investigated the ... Read more >>

Med Sci Monit (Medical science monitor : international medical journal of experimental and clinical research)
[2014, 20:1255-1262]

Cited: 27 times

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Expression of Cox-2 and Bcl-2 in Paget's disease of the breast.

Arsenal Sezgin Alikanoglu, Mustafa Yildirim, Dinc Suren, Birsel Tutus, Vildan Kaya, Cumhur Selcuk Topal, Sevinc Keser, Ayse Nimet Karadayi, Fatma Nilgun Kapucuoglu, Sebnem Ayva, Seyda Gunduz,

<h4>Background</h4>Paget's disease (PD) is a rare form of intraepithelial adenocarcinoma that involves breast and extramammarian tissues. It is often associated with ductal carcinoma in situ and/or invasive ductal cancer. Molecular pathways that play a role in development of Paget's disease are stil unclear. Expression patterns of Cox-2 and bcl-2 were ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2015, 16(3):1041-1045]

Cited: 0 times

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Prognostic significance of p53 in gastric cancer: a meta- analysis.

Mustafa Yildirim, Vildan Kaya, Ozlem Demirpence, Seyda Gunduz, Hakan Bozcuk,

<h4>Background</h4>Gastric cancer is one of the frequently seen cancers in the world and it is the second most common reason for death due to cancer. The prognostic role of expression of p53 detected by immunohistochemistry in gastric cancer remains controversial. This meta-analysis aimed to explore any association between overexpression and ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2015, 16(1):327-332]

Cited: 19 times

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Expression of cyclooxygenase-2 and Bcl-2 in breast cancer and their relationship with triple-negative disease.

Arsenal Sezgin Alikanoglu, Mustafa Yildirim, Dinc Suren, Mustafa Yildiz, Vildan Kaya, Utku Donem Dilli, Cem Sezer,

<h4>Purpose</h4>Carcinogenesis is a multistep process with many factors being involved. The aim of this study was to investigate the role of cyclooxygenase-2 (COX-2) and Bcl-2 expression in patients with triple-negative breast cancer (TNBC) and, also whether any differences exist between TNBC and non-TNBC patients in relation with these two parameters.<h4>Methods</h4>This ... Read more >>

J BUON (Journal of B.U.ON. : official journal of the Balkan Union of Oncology)
[2014, 19(2):430-434]

Cited: 4 times

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The role of high mobility group box 1 (HMGB1) in colorectal cancer.

Dinç Süren, Mustafa Yıldırım, Özlem Demirpençe, Vildan Kaya, Arsenal Sezgin Alikanoğlu, Nurullah Bülbüller, Mustafa Yıldız, Cem Sezer,

<h4>Background</h4>HMGB1, the most important member of the high mobility group box protein family, is a nuclear protein with different functions in the cell; it has a role in cancer progression, angiogenesis, invasion, and metastasis development. We studied the expression of HMGB1 and whether it is a prognostic factor in colorectal ... Read more >>

Med Sci Monit (Medical science monitor : international medical journal of experimental and clinical research)
[2014, 20:530-537]

Cited: 40 times

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Lack of any prognostic role of insulin-like growth factor-1 receptor in non-small cell lung cancer.

Utku Donem Dilli, Mustafa Yildırim, Dinc Suren, Arsenal Alikanoglu, Vildan Kaya, Sevil Goktas, Mustafa Yildiz, Cem Sezer, Seyda Gunduz,

<h4>Background</h4>The purpose of this study is to determine whether the IGF1R expression has a prognostic role in non-small cell lung cancer.<h4>Materials and methods</h4>Forty-seven patients histopathologically diagnosed with small cell lung cancer upon bronchoscopic biopsy or resection materials were included in the study. IGF1R expression was examined via immunohistochemical methods. In ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2014, 15(14):5753-5757]

Cited: 1 time

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Lack of relation of AKAP12 with p53 and Bcl-2 in colorectal carcinoma.

Dinc Suren, Mustafa Yildirim, Arsenal Sezgin Alikanoglu, Vildan Kaya, Mustafa Yildiz, Utku Donem Dilli, Cem Sezer,

<h4>Background</h4>AKAP12 inhibits oncogenic proliferation, invasion, chemotaxis and neovascularization. Bcl-2 and p53 are two important apoptotic markers that play roles in apoptotic processes. It has been found that AKAP12 blocks the cell cycle and induces apoptosis in fibrosarcoma cells. In our study we assessed the relationship of AKAP12 with apoptotic markers, ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2014, 15(8):3415-3418]

Cited: 2 times

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Association between suicidal ideation and behavior, and depression, anxiety, and perceived social support in cancer patients.

Melike Ceyhan Balcı Şengül, Vildan Kaya, Cenk Ahmet Şen, Kemal Kaya,

<h4>Background</h4>The aim of this study was to determine the relationship between suicidal behavior and associated factors such as depression, anxiety, and perceived social support level in cancer patients.<h4>Material and methods</h4>The study group included 102 patients who were under treatment in the oncology department and the control group included 100 individuals ... Read more >>

Med Sci Monit (Medical science monitor : international medical journal of experimental and clinical research)
[2014, 20:329-336]

Cited: 17 times

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Isolated and solitary splenic metastasis detected by positron emission tomography in a patient with malignant melanoma: case report and review of the literature.

Cenk Ahmet Sen, Aysegul Kargi, Vildan Kaya, Ozgur Tanriverdi,

Splenic metastasis from malignant melanoma is an extremely rare occurrence and is most often reported during autopsy. As in other solid tumors, splenic metastasis is usually part of multiple organ metastases in melanoma and is rarely an isolated or solitary mass. As the use of positron emission tomography /computed tomography ... Read more >>

Contemp Oncol (Pozn) (Contemporary oncology (Poznan, Poland))
[2013, 17(2):214-217]

Cited: 1 time

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Roles for paraoxonase but not ceruloplasmin in peritoneal washing fluid in differential diagnosis of gynecologic pathologies.

Mustafa Yildirim, Ozlem Demirpence, Vildan Kaya, Dinc Suren, Mehmet Karaca, Osman Evliyaoglu, Necat Yilmaz, Seyda Gunduz,

<h4>Background</h4>Intraperitoneal spread of gynecologic cancers is a major cause of mortality and morbidity and often presents with malignant ascites. Microscopic tumor spread can be demonstrated by a peritoneal wash cytology and help assess the prognosis of the disease. In our study, the roles of paraoxonase and ceruloplasmin, measured in peritoneal ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2014, 15(15):6233-6237]

Cited: 0 times

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Esophageal cancer, gastric cancer and the use of pesticides in the southwestern of Turkey.

Mustafa Yildirim, Vildan Kaya, Mustafa Yildiz, Ozlem Demirpence, Seyda Gunduz, Utku Donem Dilli,

<h4>Background</h4>Esophageal and gastric cancer generally have a poor prognosis and may share common risk factors. It has been demonstrated that the pesticide usage may contribute to development of many cancer types. In this study, the relation between amount of pesticides used in agriculture and esophageal and gastric cancer incidence was ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2014, 15(6):2821-2823]

Cited: 2 times

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Non-Hodgkin lymphoma and pesticide exposure in Turkey.

Mustafa Yildirim, Hulya Karakilinc, Mustafa Yildiz, Erdal Kurtoglu, Utku Donem Dilli, Sevil Goktas, Ozlem Demirpence, Vildan Kaya,

<h4>Background</h4>Non-Hodgkin lymphoma (NHL) is a solid tumour of lymphocytes, important elements in the immune system. According to 2006 data, in Turkey the incidence was 6.5 per 100,000 in males, and 4.4 in females. The relationship between the use of pesticides and development of NHL has been extensively investigated in many ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2013, 14(6):3461-3463]

Cited: 0 times

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Tumour markers in peritoneal washing fluid - contribution to cytology.

Mustafa Yıldırım, Dınc Suren, Mustafa Yıldız, Arsenal Sezgın Alikanoglu, Vildan Kaya, Suleyman Gunhan Doluoglu, Ozgur Aydın, Necat Yılmaz, Cem Sezer, Mehmet Karaca,

<h4>Background</h4>Peritoneal washing cytology (PWC) that shows the microscopic intra-peritoneal spread of gynaecologic cancers is not used in staging but is known as prognostic factor and effective in planning the intensity of the therapy. False negative or false positive results clearly affect the ability to make the best decision for therapy. ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2013, 14(2):1027-1030]

Cited: 1 time

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Prognostic significance of basic laboratory methods in non- small-cell-lung cancer.

Vildan Kaya, Mustafa Yildirim, Ozlem Demirpence, Mustafa Yildiz, Aysen Yesim Yalcin,

<h4>Background</h4>In our study, the LDH, albumin, hemoglobin, neutrophile, thrombocyte, lymphocyte counts and prognostic significance of neutrophile-lymphocyte and thrombocyte-lymphocyte ratios in NSCLC derived from these counts obtained during regular examinations of patients were examined.<h4>Materials and methods</h4>Histopathologically diagnosed non-small-cell-lung cancer patients between 2008 and 2010 were included in the study. Before the ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2013, 14(9):5473-5476]

Cited: 12 times

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