Full Text Journal Articles by
Author Vikas Gupta

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Human Behavior In A Social Environment

Naveen Sharma, Vikas Gupta,

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An Uncommon Complication of Ankle Varus During Tibial Transport in an Ilizarov Frame: A Case Report.

Vikas Gupta, Vishal Champawat, Prateek Behera, Sibasis Garnayak,

<h4>Case</h4>We treated a 22-year-old man with an infected fracture of the tibia by resection of necrosed bone and bone transport with an Ilizarov device. Four weeks after initiation of transport, an ankle varus deformity from distal migration of the fibula was noticed. A wire that had been incorrectly placed through ... Read more >>

JBJS Case Connect (JBJS case connector)
[2021, 11(4):]

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Objective Evaluation of Olfactory and Taste Dysfunction Among COVID-19 Patients: A Cross Sectional Study from Tribal India.

Izhar Khan, Vikas Gupta, Sanjay Kumar Shukla,

There is a varying prevalence of olfactory and taste dysfunction (OTD) in COVID-19 patients, with a higher prevalence reported in the European population as compared to the Asian population. Psychophysical tests are crucial to determine the exact frequency, extent and clinical characteristics of these OTDs. The present study objectively evaluated ... Read more >>

Indian J Otolaryngol Head Neck Surg (Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India)
[2021, :1-9]

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Allogeneic blood or marrow transplantation with haploidentical donor and post-transplantation cyclophosphamide in patients with myelofibrosis: a multicenter study.

Siddharth Kunte, Lisa Rybicki, Auro Viswabandya, Roni Tamari, Asad Bashey, Alla Keyzner, Madiha Iqbal, Michael R Grunwald, Bhagirathbhai Dholaria, Hany Elmariah, Michael Ozga, Anurag Singh, Sameem Abedin, Amy E DeZern, Richard J Jones, Vikas Gupta, Aaron T Gerds, Tania Jain,

We report the results from a multicenter retrospective study of 69 adult patients who underwent haploidentical blood or marrow transplantation (haplo-BMT) with post-transplantation cyclophosphamide (PTCy) for chronic phase myelofibrosis. The median age at BMT was 63 years (range, 41-74). Conditioning regimens were reduced intensity in 54% and nonmyeloablative in 39%. ... Read more >>

Leukemia (Leukemia)
[2021, :]

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Benefits of Autologous Stem Cell Transplantation for Elderly Myeloma Patients in the Last Quarter of Life.

Nisha S Joseph, Vikas A Gupta, Sarah Wyman, Michael Graiser, Jonathan L Kaufman, Dhwani Almaula, Joel Andrews, Craig Hofmeister, Madhav Dhodapkar, Leonard T Heffner, Sagar Lonial, Ajay K Nooka,

Although survival outcomes have improved dramatically over the last few decades in newly diagnosed myeloma patients, elderly patients have not yielded the same magnitude of benefit as evidenced by higher rates of reported myeloma-related deaths in patients over the age of 75. This is of particular importance given this cohort ... Read more >>

Transplant Cell Ther (Transplantation and cellular therapy)
[2021, :]

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Neuroendocrine Tumours of Extrahepatic Biliary Tract: Series of Four Cases with Literature Review

Amit Chopde, Vikas Gupta, Akshaya Jadhav, Rajiv Kaushal, Mukta Ramadwar, Shraddha Patkar, Mahesh Goel,

Neuroendocrine tumours (NETs) originating from extrahepatic bile duct are an extremely rare entity. They are typically slow growing tumours with malignant potential. Commonly presenting as obstructive jaundice, preoperative clinico-radiologic differentiation between extrahepatic biliary tract neuroendocrine tumours and cholangiocarcinoma is difficult and the final diagnosis is usually established after surgical histopathology ... Read more >>

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En bloc resection in giant bilobed splenic artery aneurysm.

Venu Bhargava Mulpuri, Jayanta Samanta, Pankaj Gupta, Vikas Gupta,

Giant splenic artery aneurysms are rare and associated with high morbidity and mortality. Early detection is the key to decreasing morbidity and mortality. We present a giant splenic artery aneurysm which was managed by en bloc resection of the spleen, distal pancreas. ... Read more >>

BMJ Case Rep (BMJ case reports)
[2021, 14(9):]

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Extracorporeal Life Support for Respiratory Failure in Patients With Electronic Cigarette or Vaping Product Use-Associated Lung Injury.

Vikas S Gupta, Don Hayes, Stephanie C Hsu, Joseph E Tonna, Peter T Rycus, Brian C Bridges, Fatima Diaban, Karen J Bosma, Jayesh M Bhatt, Nicole M Sakla, Jason J Han, Christian A Bermudez, Frank Manetta, Elisa I Garcia, Matthew T Harting,

<h4>Objectives</h4>Electronic cigarette or vaping product use-associated lung injury is a clinical entity that can lead to respiratory failure and death. Despite the severity of electronic cigarette or vaping product use-associated lung injury, the role of extracorporeal life support in its management remains unclear. Our objective was to describe the clinical ... Read more >>

Crit Care Med (Critical care medicine)
[2021, :]

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Critical illness in patients with hematologic malignancy: a population-based cohort study.

Bruno L Ferreyro, Damon C Scales, Hannah Wunsch, Matthew C Cheung, Vikas Gupta, Refik Saskin, Santhosh Thyagu, Laveena Munshi,

<h4>Purpose</h4>To describe the modern incidence and predictors of ICU admission for adult patients newly diagnosed with a hematologic malignancy.<h4>Methods</h4>We conducted a population-based cohort study of adults with a new diagnosis of hematologic malignancy (April 1, 2006-March 31, 2017) in Ontario, Canada. We described the baseline demographic, clinical and laboratory predictors ... Read more >>

Intensive Care Med (Intensive care medicine)
[2021, 47(10):1104-1114]

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Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia

Akhilesh Kaushal, Ajay K. Nooka, Allison R. Carr, Katherine E. Pendleton, Benjamin G. Barwick, Julia Manalo, Samuel S. McCachren, Vikas A. Gupta, Nisha S. Joseph, Craig C. Hofmeister, Jonathan L. Kaufman, Leonard T. Heffner, Stephen M. Ansell, Lawrence H. Boise, Sagar Lonial, Kavita M. Dhodapkar, Madhav V. Dhodapkar,

A distinct immune landscape marked by features across immune cell types, including nonmalignant B cells and early lymphoid progenitors, establishes an environment conducive to WM. Waldenstrom macroglobulinemia (WM) and its precursor IgM gammopathy are distinct disorders characterized by clonal mature IgM-expressing B-cell outgrowth in the bone marrow. Here, we show ... Read more >>

Blood Cancer Discov (Blood cancer discovery)
[2021, 2(6):600-615]

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Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia.

Akhilesh Kaushal, Ajay K Nooka, Allison R Carr, Katherine E Pendleton, Benjamin G Barwick, Julia Manalo, Samuel S McCachren, Vikas A Gupta, Nisha S Joseph, Craig C Hofmeister, Jonathan L Kaufman, Leonard T Heffner, Stephen M Ansell, Lawrence H Boise, Sagar Lonial, Kavita M Dhodapkar, Madhav V Dhodapkar,

Waldenstrom macroglobulinemia (WM) and its precursor IgM gammopathy are distinct disorders characterized by clonal mature IgM-expressing B-cell outgrowth in the bone marrow. Here, we show by high-dimensional single-cell immunogenomic profiling of patient samples that these disorders originate in the setting of global B-cell compartment alterations, characterized by expansion of genomically ... Read more >>

Blood Cancer Discov (Blood cancer discovery)
[2021, 2(6):600-615]

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A cross-sectional study to assess the utilization pattern of maternal health services and associated factors in aspirational district of Haryana, India.

Abhishek Singh, Subramani Palaniyandi, Anitha Palaniyandi, Vikas Gupta, Ram Kumar Panika, Rakesh Kumar Mahore, Pawan Kumar Goel,

<h4>Background</h4>In India mother related mortalities and morbidities are still significantly higher even after having various maternal program and schemes at regional and national level which reflects that such services are being under-utilized.<h4>Aim</h4>The current study focused in assessing utilization pattern of maternal health services and associated factors in Nuh (Mewat).<h4>Methods</h4>This present ... Read more >>

J Family Med Prim Care (Journal of family medicine and primary care)
[2021, 10(8):2879-2885]

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Prophylactic ligation of the opacified thoracic duct in minimally invasive esophagectomy - feasibility and safety.

Lunkhomba Takhellambam, Thakur Deen Yadav, Hemanth Kumar, Vikas Gupta, Cherring Tandup, Ujjwal Gorsi, Vishal Sharma, Harshal Mandhavdhare, Tanvir Samra, Harjeet Singh,

<h4>Background</h4>Chyle leak is a rare but morbid complication of esophagectomy. We assessed the feasibility of visualization and prophylactic ligation of the opacified thoracic duct (TD) after administration of 50 ml of olive oil.<h4>Methods</h4>This prospective single center study considered all patients with carcinoma of the middle and lower thirds of the ... Read more >>

Langenbecks Arch Surg (Langenbeck's archives of surgery)
[2021, 406(7):2515-2520]

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Does Preoperative Serum Neutrophil to Lymphocyte Ratio (NLR), Platelet to Lymphocyte Ratio (PLR), and Lymphocyte to Monocyte Ratio (LMR) Predict Prognosis Following Radical Surgery for Pancreatic Adenocarcinomas? Results of a Retrospective Study.

Vikas Gupta, Vikram Chaudhari, Shailesh V Shrikhande, Manish S Bhandare,

<h4>Background</h4>Pretherapy serum neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and lymphocyte to monocyte ratio (LMR) have been shown to predict prognosis in patients with pancreatic ductal adenocarcinoma (PDAC). However, the published literature is conflicting; hence, we aimed to evaluate their role in predicting survival outcomes in operated ... Read more >>

J Gastrointest Cancer (Journal of gastrointestinal cancer)
[2021, :]

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Surgical Management of Solid Pseudopapillary Neoplasm of Pancreas- An Experience from Tertiary Care Centre

Rohit Bhatta, Santosh Irrinki, Vikas Gupta, Thakur Deen Yadav, Yashwant Raj Sakaray, Hemanth Kumar, Ritambhra Nada, Harjeet Singh,

<h4>Background: </h4> Solid Pseudopapillary neoplasm (SPN) is uncommon and constitutes to 1-2% of pancreatic tumors. Owing to its rarity, literature is spare on its clinicopathological characteristics and surgical outcomes. <h4>Methods: </h4> Our study is a retrospective analysis of prospectively maintained data of patients with histologically proven SPN between January,2012 and ... Read more >>

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How We Did It: Implementing a Trainee-Focused Surgical Research Curriculum and Infrastructure.

Vikas S Gupta, Jennie Meier, Johanna H Nunez, Kareem R Abdelfattah, Courtney Balentine, Herb J Zeh, Deborah Carlson, Benjamin Levi,

<h4>Objective</h4>To describe the implementation of a department-wide research curriculum and infrastructure created to promote academic collaboration and productivity, particularly amongst trainees and junior investigators involved in basic, translational, clinical, quality, or education research.<h4>Design</h4>Description of UT Southwestern Medical Center's (UTSW) surgical research resources and infrastructure and the development of a didactic ... Read more >>

J Surg Educ (Journal of surgical education)
[2021, :]

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A cross-sectional study to assess the utilization pattern of maternal health services and associated factors in aspirational district of Haryana, India

Abhishek Singh, Subramani Palaniyandi, Anitha Palaniyandi, Vikas Gupta, Ram Kumar Panika, Rakesh Kumar Mahore, Pawan Kumar Goel,

<h4>Background:</h4> In India mother related mortalities and morbidities are still significantly higher even after having various maternal program and schemes at regional and national level which reflects that such services are being under-utilized. <h4>Aim:</h4> The current study focused in assessing utilization pattern of maternal health services and associated factors in ... Read more >>

J Family Med Prim Care (Journal of family medicine and primary care)
[2021, 10(8):2879-2885]

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Impact of Different Patterns of Organ Failure on Mortality in Acute Necrotizing Pancreatitis.

Anupam K Singh, Jayanta Samanta, Jayendra Shukla, Chhagan Lal Birda, Jahnvi Dhar, Pankaj Gupta, Praveen Kumar-M, Vikas Gupta, Thakur Deen Yadav, Saroj K Sinha, Rakesh Kochhar,

<h4>Objectives</h4>Organ failure (OF) and infected necrosis (IN) are the most important predictors of mortality in necrotizing acute pancreatitis (AP). We studied the relationship between timing (onset and duration) and patterns of OF with mortality and the impact of IN on mortality.<h4>Methods</h4>Consecutive patients with necrotizing AP between January 2017 and February ... Read more >>

Pancreas (Pancreas)
[2021, 50(7):1030-1036]

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Effect of pre-transplant JAK1/2 inhibitors and CD34 dose on transplant outcomes in myelofibrosis.

Sunu Cyriac, Shruti Prem, Maria Queralt Salas, Shiyi Chen, Zeyad Al-Shaibani, Wilson Lam, Arjun Law, Vikas Gupta, Fotios V Michelis, Dennis Dong Hwan Kim, Jeffrey Lipton, Rajat Kumar, Jonas Mattsson, Auro Viswabandya,

Allogeneic hematopoeitic cell transplantation (allo-HCT) is the only curative treatment for myelofibrosis (MF). We evaluate the impact of various factors on survival outcomes post-transplant in MF. Data of 89 consecutive MF patients (primary 47%) who underwent allo-HCT between 2005 and 2018 was evaluated. Fifty-four percent patients had received JAK1/2 inhibitors ... Read more >>

Eur J Haematol (European journal of haematology)
[2021, 107(5):517-528]

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Mortality in Congenital Diaphragmatic Hernia: A Multicenter Registry Study of Over 5000 Patients Over 25 Years.

Vikas S Gupta, Matthew T Harting, Pamela A Lally, Charles C Miller, Ronald B Hirschl, Carl F Davis, Melvin S Dassinger, Terry L Buchmiller, Krisa P Van Meurs, Bradley A Yoder, Michael J Stewart, Kevin P Lally, ,

<h4>Objective</h4>To determine if risk-adjusted survival of patients with congenital diaphragmatic hernia (CDH) has improved over the last 25 years within centers that are long-term, consistent participants in the CDH Study Group (CDHSG).<h4>Summary background data</h4>The CDHSG is a multicenter collaboration focused on evaluation of infants with CDH. Despite advances in pediatric surgical ... Read more >>

Ann Surg (Annals of surgery)
[2021, :]

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Telemedicine as a component of forward triage in a pandemic.

Vikas S Gupta, Elizabeth C Popp, Elisa I Garcia, Sahar Qashqai, Christy Ankrom, Tzu-Ching Wu, Matthew T Harting,

<h4>Objective(s)</h4>Coronavirus disease 2019 (COVID-19) presents an enormous challenge to healthcare systems globally. Optimizing access to healthcare while minimizing face-to-face patient encounters is critical to limiting exposures, conserving resources, and preserving health. We aimed to evaluate the utility of a COVID-focused telehealth program in avoiding potential in-person visits while maintaining high ... Read more >>

Healthc (Amst) (Healthcare (Amsterdam, Netherlands))
[2021, 9(3):100567]

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Diagnosis of gastric submucosal tumors and estimation of malignant risk of GIST by endoscopic ultrasound. Comparison between B mode and contrast-harmonic mode.

Christine Lefort, Vikas Gupta, Andrea Lisotti, Laurent Palazzo, Pietro Fusaroli, Bertrand Pujol, Rodica Gincul, Fabien Fumex, Maxime Palazzo, Bertrand Napoléon,

<h4>Background</h4>standard B-mode EUS assessment and EUS-guided tissue acquisition present sub-optimal diagnostic yield in the differential diagnosis of gastric submucosal tumors (SMTs).<h4>Aims</h4>to evaluate the performances of contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) to differentiate gastric SMTs and predict malignancy risk of gastrointestinal stromal tumors (GIST).<h4>Methods</h4>a retrospective analysis was performed retrieving consecutive patients ... Read more >>

Dig Liver Dis (Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver)
[2021, 53(11):1486-1491]

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Comparing the safety and efficacy of ruxolitinib in patients with Dynamic International Prognostic Scoring System low-, intermediate-1-, intermediate-2-, and high-risk myelofibrosis in JUMP, a Phase 3b, expanded-access study.

Francesco Passamonti, Vikas Gupta, Bruno Martino, Lynda Foltz, Andrey Zaritskey, Haifa Kathrin Al-Ali, Renato Tavares, Margherita Maffioli, Pia Raanani, Pilar Giraldo, Martin Griesshammer, Paola Guglielmelli, Catherine Bouard, Carole Paley, Ranjan Tiwari, Alessandro M Vannucchi,

Ruxolitinib, a potent Janus kinase 1/2 inhibitor, has demonstrated durable improvements in patients with myelofibrosis. In this analysis of the Phase 3b JUMP study, which included patients aged ≥18 years with a diagnosis of primary or secondary myelofibrosis, we assessed the safety and efficacy of ruxolitinib in patients stratified by ... Read more >>

Hematol Oncol (Hematological oncology)
[2021, 39(4):558-566]

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Does Preoperative Serum Neutrophil To Lymphocyte Ratio (NLR), Platelet To Lymphocyte Ratio (PLR) And Lymphocyte To Monocyte Ratio (LMR) Predict Prognosis Following Radical Surgery For Pancreatic Adenocarcinomas? - Results of A Retrospective Study.

Vikas Bachelal Gupta, Vikram Chaudhari, Shailesh Shrikhande, Manish Bhandare,

<h4>Background: </h4> Pretherapy serum neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and lymphocyte to monocyte ratio (LMR) have been shown to predict prognosis in patients with pancreatic ductal adenocarcinoma (PDAC). However, the published literature is conflicting, hence we aimed to evaluate their role in predicting survival outcomes ... Read more >>

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Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression.

Vikas A Gupta, Benjamin G Barwick, Shannon M Matulis, Ryosuke Shirasaki, David L Jaye, Jonathan J Keats, Benjamin Oberlton, Nisha S Joseph, Craig C Hofmeister, Leonard T Heffner, Madhav V Dhodapkar, Ajay K Nooka, Sagar Lonial, Constantine S Mitsiades, Jonathan L Kaufman, Lawrence H Boise,

Venetoclax is a highly potent, selective BCL2 inhibitor capable of inducing apoptosis in cells dependent on BCL2 for survival. Most myeloma is MCL1-dependent; however, a subset of myeloma enriched for translocation t(11;14) is codependent on BCL2 and thus sensitive to venetoclax. The biology underlying this heterogeneity remains poorly understood. We ... Read more >>

Blood (Blood)
[2021, 137(26):3604-3615]

Cited: 4 times

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