Full Text Journal Articles by
Author Vijay Kher

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Paired Kidney Exchange Transplantation - Pushing the boundaries.

Vijay Kher, Pranaw Kumar Jha,

The scarcity of living organ donors makes it imperative to develop newer innovations to optimize and maximize the utilization of the available pool. ABO and HLA sensitization are important immunological barriers in renal transplant and can potentially lead to rejection of almost one-third of the willing living donors. Paired kidney ... Read more >>

Transpl. Int. (Transplant international : official journal of the European Society for Organ Transplantation)
[2020, :]

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Intradialytic Hypotension and Cardiac Arrhythmias in Patients Undergoing Maintenance Hemodialysis: Results from the Monitoring in Dialysis Study.

Finnian R Mc Causland, Jim A Tumlin, Prabir Roy-Chaudhury, Bruce A Koplan, Alexandru I Costea, Vijay Kher, Don Williamson, Saurabh Pokhariyal, David M Charytan, ,

BACKGROUND AND OBJECTIVES:Patients receiving maintenance hemodialysis (HD) have a high incidence of cardiac events, including arrhythmia and sudden death. Intradialytic hypotension (IDH) is a common complication of HD and is associated with development of reduced myocardial perfusion, a potential risk factor for arrhythmia. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS:We analyzed data ... Read more >>

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2020, 15(6):805-812]

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Mystery of black urine: alkaptonuria.

Sidharth Kumar Sethi, Rupesh Raina, Ronith Chakraborty, Vijay Kher,

Kidney Int. (Kidney international)
[2020, 97(6):1303]

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Multidisciplinary Consensus Document on the Management of Uncontrolled Hypertension in India.

R Padmanabhan, Rana Gopal Singh, Govindan Unni, Bhupen Desai, Sanjeev Kumar Hiremath, Vidyut Jain, Saikat Bhawal, Sanjeev Gulati, Mukesh Shete, Ramesh Nair, Sunil Prakash, Vijay Kher, Bijan Bhattacharya,

Cardiovascular disease is predicted to be the largest cause of death and disability in India by 2020. Hypertension (HT), one of the main contributing factors, presents a significant public health burden. Inability to achieve adequate blood pressure (BP) control results in uncontrolled hypertension (UHT). The prevalence of UHT is high ... Read more >>

High Blood Press Cardiovasc Prev (High Blood Pressure & Cardiovascular Prevention)
[2020, 27(3):215-223]

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Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease.

John A Spertus, Philip G Jones, David J Maron, Daniel B Mark, Sean M O'Brien, Jerome L Fleg, Harmony R Reynolds, Gregg W Stone, Mandeep S Sidhu, Bernard R Chaitman, Glenn M Chertow, Judith S Hochman, Sripal Bangalore, ,

BACKGROUND:In the ISCHEMIA-CKD trial, the primary analysis showed no significant difference in the risk of death or myocardial infarction with initial angiography and revascularization plus guideline-based medical therapy (invasive strategy) as compared with guideline-based medical therapy alone (conservative strategy) in participants with stable ischemic heart disease, moderate or severe ischemia, ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2020, 382(17):1619-1628]

Cited: 1 time

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Management of Coronary Disease in Patients with Advanced Kidney Disease.

Sripal Bangalore, David J Maron, Sean M O'Brien, Jerome L Fleg, Evgeny I Kretov, Carlo Briguori, Upendra Kaul, Harmony R Reynolds, Tomasz Mazurek, Mandeep S Sidhu, Jeffrey S Berger, Roy O Mathew, Olga Bockeria, Samuel Broderick, Radoslaw Pracon, Charles A Herzog, Zhen Huang, Gregg W Stone, William E Boden, Jonathan D Newman, Ziad A Ali, Daniel B Mark, John A Spertus, Karen P Alexander, Bernard R Chaitman, Glenn M Chertow, Judith S Hochman, ,

BACKGROUND:Clinical trials that have assessed the effect of revascularization in patients with stable coronary disease have routinely excluded those with advanced chronic kidney disease. METHODS:We randomly assigned 777 patients with advanced kidney disease and moderate or severe ischemia on stress testing to be treated with an initial invasive strategy consisting ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2020, 382(17):1608-1618]

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Pediatric Continuous Renal Replacement Therapy (PCRRT) expert committee recommendation on prescribing prolonged intermittent renal replacement therapy (PIRRT) in critically ill children.

Sidharth Kumar Sethi, Aliza Mittal, Nikhil Nair, Arvind Bagga, Arpana Iyenger, Uma Ali, Rajiv Sinha, Indira Agarwal, Marcelo de Sousa Tavares, Asiri Abeyagunawardena, Mohammed Hanif, Devender Shreshtha, Khemchand Moorani, Sadaf Asim, Vijay Kher, Khalid Alhasan, Chebl Mourani, Mohammed Al Riyami, Timothy E Bunchman, Mignon McCulloch, Rupesh Raina,

INTRODUCTION:Recently, prolonged intermittent renal replacement therapies (PIRRT) have emerged as cost-effective alternatives to conventional CRRT and their use in the pediatric population has started to become more prominent. However, there is a lack of consensus guidelines on the use of PIRRT in pediatric patients in an intensive care setting. METHODS:A ... Read more >>

Hemodial Int (Hemodialysis international. International Symposium on Home Hemodialysis)
[2020, 24(2):237-251]

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A boy with IgA vasculitis and anuria: Questions.

Vivek Sharma, Sidharth Kumar Sethi, Rupesh Raina, Shyam Bansal, S S Baijal, Vijay Kher,

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2020, 35(3):399-400]

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A boy with IgA vasculitis and anuria: Answers.

Vivek Sharma, Sidharth Kumar Sethi, Rupesh Raina, Shyam Bansal, S S Baijal, Vijay Kher,

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2020, 35(3):401-402]

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Utility or futility of Interleukin 2 receptor antagonist (IL2RA) induction in kidney transplants-the devil is in the detail.

Ajay Kher, Vijay Kher,

Transpl. Int. (Transplant international : official journal of the European Society for Organ Transplantation)
[2019, 32(8):794-796]

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Study to Test and Operationalize Preventive Approaches for CKD of Undetermined Etiology in Andhra Pradesh, India.

Oommen John, Balaji Gummidi, Abha Tewari, J P Muliyil, Arpita Ghosh, Meena Sehgal, Abhinav Bassi, Shankar Prinja, Vivek Kumar, Om P Kalra, Vijay Kher, J S Thakur, Lakshmy Ramakrishnan, C M Pandey, V Sivakumar, R S Dhaliwal, Tripti Khanna, Aruna Kumari, Jitender Sharma, Poonam Malakondiah, Vivekanand Jha,

Introduction:High prevalence of chronic kidney disease (CKD) not associated with known risk factors has been reported from coastal districts of Andhra Pradesh. The Study to Test and Operationalize Preventive Approaches for Chronic Kidney Disease of Undetermined Etiology in Andhra Pradesh (STOP CKDu AP) aims to ascertain the burden (prevalence and ... Read more >>

Kidney Int Rep (Kidney International Reports)
[2019, 4(10):1412-1419]

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Methodological challenges to collecting clinical and economic outcome data: Lessons from the pilot dialysis outcomes India study.

Abhinav Bassi, Oommen John, Martin Gallagher, Sradha Kotwal, Rohina Joshi, Beverley Essue, Stephen Jan, Raja Ramachandran, Vijay Kher, John Knight, Vivekanand Jha,

AIM:Contemporary data on clinical and economic outcomes and quality of care amongst dialysis patients in India are not available. This pilot prospective study aimed to evaluate the feasibility of data collection and follow up within routine dialysis practice to inform setting up a dialysis registry. METHODS:An electronic instrument was developed ... Read more >>

Nephrology (Carlton) (Nephrology (Carlton, Vic.))
[2019, 24(4):445-449]

Cited: 1 time

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Relationship between dialytic parameters and reviewer confirmed arrhythmias in hemodialysis patients in the monitoring in dialysis study.

James A Tumlin, Prabir Roy-Chaudhury, Bruce A Koplan, Alexandru I Costea, Vijay Kher, Don Williamson, Saurabh Pokhariyal, David M Charytan, ,

BACKGROUND:Hemodialysis patients have high rates of sudden death, but relationships between serum electrolytes, the dialysis prescription, and intra-dialytic shifts in fluid and electrolyte with arrhythmia are uncertain. METHODS:We analyzed sixty-six hemodialysis patients who underwent loop recorder implantation with continuous electrocardiographic monitoring, weekly to bi-weekly testing of pre- and post-dialysis electrolytes, ... Read more >>

BMC Nephrol (BMC nephrology)
[2019, 20(1):80]

Cited: 1 time

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Identification of PKD1 and PKD2 gene variants in a cohort of 125 Asian Indian patients of ADPKD.

Shewata Pandita, Vijaya Ramachandran, Prahlad Balakrishnan, Arndt Rolfs, Oliver Brandau, Sabrina Eichler, Anil Kumar Bhalla, Dinesh Khullar, Vindu Amitabh, Sivaramakrishnan Ramanarayanan, Vijay Kher, Jyotsna Verma, Sudha Kohli, Renu Saxena, Ishwar Chander Verma,

Autosomal Dominant Polycystic Kidney Disease (ADPKD) accounts for 2.6% of the patients with chronic kidney disease in India. ADPKD is caused by pathogenic variants in either PKD1 or PKD2 gene. There is no comprehensive genetic data from Indian subcontinent. We aimed to identify the pathogenic variants in the heterogeneous Indian ... Read more >>

J. Hum. Genet. (Journal of human genetics)
[2019, 64(5):409-419]

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Myelofibrosis-Induced Erythropoietin-Resistant Anemia Due to Severe Refractory Hyperparathyroidism.

Sidharth Kumar Sethi, Shyam Bihari Bansal, Nikita Wadhwani, Mayur Makasana, Ashish Nandwani, Vijay Kher, Rupesh Raina,

Kidney Int Rep (Kidney International Reports)
[2018, 3(4):1010-1014]

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Primary outcomes of the Monitoring in Dialysis Study indicate that clinically significant arrhythmias are common in hemodialysis patients and related to dialytic cycle.

Prabir Roy-Chaudhury, Jim A Tumlin, Bruce A Koplan, Alexandru I Costea, Vijay Kher, Don Williamson, Saurabh Pokhariyal, David M Charytan, ,

Sudden death is one of the more frequent causes of death for hemodialysis patients, but the underlying mechanisms, contribution of arrhythmia, and associations with serum chemistries or the dialysis procedure are incompletely understood. To study this, implantable loop recorders were utilized for continuous cardiac rhythm monitoring to detect clinically significant ... Read more >>

Kidney Int. (Kidney international)
[2018, 93(4):941-951]

Cited: 24 times

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Haemodialysis vascular access: current practices amongst Indian nephrologists.

Dinesh Bansal, Vijay Kher, Krishan Lal Gupta, Debasish Banerjee, Vivekanand Jha,

Despite the growing number of haemodialysis (HD) patients in India, little is known about vascular access practice. We investigated the use and cost of different vascular accesses by Indian nephrologists.An online survey was emailed to 920 Indian nephrologists and 388 (42.1%) responded; 98.5% of whom were responsible for managing dialysis ... Read more >>

J Vasc Access (The journal of vascular access)
[2018, 19(2):172-176]

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Pediatric ABO-incompatible kidney transplantation: Evolving with the advancing apheresis technology: A single-center experience.

Sidharth Kumar Sethi, Shyam Bihari Bansal, Nikita Wadhwani, Aseem Tiwari, Dinesh Arora, Reetesh Sharma, Ashish Nandwani, Dinesh Kumar Yadav, Amit Kumar Mahapatra, Manish Jain, Pranaw Jha, Prasun Ghosh, Anil Bhan, Maninder Dhaliwal, Veena Raghunathan, Vijay Kher,

Recent literature has endorsed favorable outcomes following ABOi kidney transplantation in pediatric population. Nevertheless, reluctance to pursue an ABOi still remains pervasive. This could be ascribed to various legitimate reasons, namely less extensive pediatric ABOi data, technical difficulties encountered during PP, cost restraints, and concerns regarding higher rates of antibody-mediated ... Read more >>

Pediatr Transplant (Pediatric transplantation)
[2018, 22(3):e13138]

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Feasibility of sustained low efficiency dialysis in critically sick pediatric patients: A multicentric retrospective study.

Sidharth K Sethi, Rajiv Sinha, Pranaw Jha, Nikita Wadhwani, Veena Raghunathan, Maninder Dhaliwal, Shyam B Bansal, Vijay Kher, Valentine Lobo, Jyoti Sharma, Rupesh Raina,

INTRODUCTION:Sustained low-efficiency dialysis (SLED) has emerged as a cost effective alternative to Continuous Renal Replacement Therapy in the management of hemodynamically unstable adult patients with acute kidney injury. The objective of the study was to document the SLED practices in these centers, and to look at the feasibility, and tolerability ... Read more >>

Hemodial Int (Hemodialysis international. International Symposium on Home Hemodialysis)
[2018, 22(2):228-234]

Cited: 1 time

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A novel CFHR1-CFHR5 hybrid leads to a familial dominant C3 glomerulopathy.

Shambhuprasad K Togarsimalemath, Sidharth K Sethi, Rajan Duggal, Moglie Le Quintrec, Pranaw Jha, RĂ©gis Daniel, Florence Gonnet, Shyam Bansal, Lubka T Roumenina, Veronique Fremeaux-Bacchi, Vijay Kher, Marie-Agnes Dragon-Durey,

The intrinsic similarity shared between the members of the complement factor H family, which comprises complement factor H and five complement factor H-related (CFHR) genes, leads to various recombination events. In turn these events lead to deletions of some genes or abnormal proteins, which are found in patients with atypical ... Read more >>

Kidney Int. (Kidney international)
[2017, 92(4):876-887]

Cited: 11 times

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Prevention and Therapy of Acute Kidney Injury in the Developing World.

Vijay Kher, Nattachai Srisawat, Eisei Noiri, Mohammed Benghanem Gharbi, Manjunath S. Shetty, Li Yang, Arvind Bagga, Rajasekara Chakravarthi, Ravindra Mehta,

Timely recognition of patients at risk or with possible acute kidney injury (AKI) is essential for early intervention to minimize further damage and improve outcome. Initial management of patients with suspected and persistent AKI should include thorough clinical assessment of all patients with AKI to identify reversible factors, including fluid ... Read more >>

Kidney Int Rep (Kidney International Reports)
[2017, 2(4):544-558]

Cited: 2 times

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Uncommon cause of fever in a pediatric kidney transplant recipient: Questions.

Sidharth Kumar Sethi, Nikita Wadhwani, Pranaw Jha, Rajan Duggal, Reetesh Sharma, Shyam Bansal, Vijay Kher,

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2017, 32(9):1525-1526]

Cited: 0 times

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Pediatric renal transplant practices in India.

Sidharth Kumar Sethi, Rajiv Sinha, Smriti Rohatgi, Vijay Kher, Arpana Iyengar, Arvind Bagga,

Limited access to tertiary-level health care, limited trained pediatric nephrologists and transplant physicians, lack of facilities for dialysis, lack of an effective deceased donor program, non-affordability, and non-adherence to immunosuppressant drugs poses a major challenge to universal availability of pediatric transplantation in developing countries. We present the results of a ... Read more >>

Pediatr Transplant (Pediatric transplantation)
[2017, 21(3):]

Cited: 3 times

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Median channel shift less than the cutoff in flow cytometric crossmatch: Not to be ignored!

Pranav Dorwal, Shyam Bihari Bansal, Rajni Chauhan, Dharmendra Jain, Vimarsh Raina, Vijay Kher,

Asian J Transfus Sci (Asian journal of transfusion science)
[2017, 11(1):73-75]

Cited: 0 times

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Uncommon cause of fever in a pediatric kidney transplant recipient: Answers.

Sidharth Kumar Sethi, Nikita Wadhwani, Pranaw Jha, Rajan Duggal, Reetesh Sharma, Shyam Bansal, Vijay Kher,

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2017, 32(9):1527-1529]

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