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Author Victor Aboyans

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Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial.

Kausik K Ray, Helen M Colhoun, Michael Szarek, Marie Baccara-Dinet, Deepak L Bhatt, Vera A Bittner, Andrzej J Budaj, Rafael Diaz, Shaun G Goodman, Corinne Hanotin, Robert A Harrington, J Wouter Jukema, Virginie Loizeau, Renato D Lopes, Angèle Moryusef, Jan Murin, Robert Pordy, Arsen D Ristic, Matthew T Roe, José Tuñón, Harvey D White, Andreas M Zeiher, Gregory G Schwartz, Philippe Gabriel Steg, ,

BACKGROUND:After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction in mean LDL cholesterol to 1·4-1·8 mmol/L with ezetimibe or statins reduces cardiovascular events in patients with an acute coronary syndrome and diabetes. However, the efficacy and safety of further reduction in LDL cholesterol with ... Read more >>

Lancet Diabetes Endocrinol (The lancet. Diabetes & endocrinology)
[2019, :]

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Mechanical left ventricular dispersion in aortic stenosis: another parameter within dispersed surrogates of myocardial function?

Julien Magne, Victor Aboyans,

Eur Heart J Cardiovasc Imaging (European heart journal cardiovascular Imaging)
[2019, 20(7):749-750]

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Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia.

Michael S Conte, Andrew W Bradbury, Philippe Kolh, John V White, Florian Dick, Robert Fitridge, Joseph L Mills, Jean-Baptiste Ricco, Kalkunte R Suresh, M Hassan Murad, Victor Aboyans, Murat Aksoy, Vlad-Adrian Alexandrescu, David Armstrong, Nobuyoshi Azuma, Jill Belch, Michel Bergoeing, Martin Bjorck, Nabil Chakfé, Stephen Cheng, Joseph Dawson, Eike S Debus, Andrew Dueck, Susan Duval, Hans H Eckstein, Roberto Ferraresi, Raghvinder Gambhir, Mauro Garguilo, Patrick Geraghty, Steve Goode, Bruce Gray, Wei Guo, Prem C Gupta, Robert Hinchliffe, Prasad Jetty, Kimihiro Komori, Lawrence Lavery, Wei Liang, Robert Lookstein, Matthew Menard, Sanjay Misra, Tetsuro Miyata, Greg Moneta, Jose A Munoa Prado, Alberto Munoz, Juan E Paolini, Manesh Patel, Frank Pomposelli, Richard Powell, Peter Robless, Lee Rogers, Andres Schanzer, Peter Schneider, Spence Taylor, Melina V De Ceniga, Martin Veller, Frank Vermassen, Jinsong Wang, Shenming Wang, ,

GUIDELINE SUMMARY:Chronic limb-threatening ischemia (CLTI) is associated with mortality, amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are focused on definition, evaluation, and management of CLTI with the goals of improving evidence-based care and highlighting critical research needs. The term CLTI is preferred over critical limb ischemia, ... Read more >>

Eur J Vasc Endovasc Surg (European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery)
[2019, 58(1S):S1-S109.e33]

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Global vascular guidelines on the management of chronic limb-threatening ischemia.

Michael S Conte, Andrew W Bradbury, Philippe Kolh, John V White, Florian Dick, Robert Fitridge, Joseph L Mills, Jean-Baptiste Ricco, Kalkunte R Suresh, M Hassan Murad, , Victor Aboyans, Murat Aksoy, Vlad-Adrian Alexandrescu, David Armstrong, Nobuyoshi Azuma, Jill Belch, Michel Bergoeing, Martin Bjorck, Nabil Chakfé, Stephen Cheng, Joseph Dawson, Eike Sebastian Debus, Andrew Dueck, Susan Duval, Hans Henning Eckstein, Roberto Ferraresi, Raghvinder Gambhir, Mauro Gargiulo, Patrick Geraghty, Steve Goode, Bruce Gray, Wei Guo, Prem Chand Gupta, Robert Hinchliffe, Prasad Jetty, Kimihiro Komori, Lawrence Lavery, Wei Liang, Robert Lookstein, Matthew Menard, Sanjay Misra, Tetsuro Miyata, Greg Moneta, Jose Antonio Munoa Prado, Alberto Munoz, Juan Esteban Paolini, Manesh Patel, Frank Pomposelli, Richard Powell, Peter Robless, Lee Rogers, Andres Schanzer, Peter Schneider, Spence Taylor, Melina Vega De Ceniga, Martin Veller, Frank Vermassen, Jinsong Wang, Shenming Wang,

Chronic limb-threatening ischemia (CLTI) is associated with mortality, amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are focused on definition, evaluation, and management of CLTI with the goals of improving evidence-based care and highlighting critical research needs. The term CLTI is preferred over critical limb ischemia, as ... Read more >>

J. Vasc. Surg. (Journal of vascular surgery)
[2019, 69(6S):3S-125S.e40]

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Ankle Brachial Index (ABI) predicts 2-year mortality risk among older adults in the Republic of Congo: The EPIDEMCA-FU study.

Harielle Samba, Maëlenn Guerchet, Bébène Ndamba-Bandzouzi, Gilles Kehoua, Pascal Mbelesso, Ileana Desormais, Victor Aboyans, Pierre-Marie Preux, Philippe Lacroix,

BACKGROUND AND AIMS:Peripheral artery disease (PAD) is known to be associated with mortality in high income countries but no data regarding Sub-Saharan Africa (SSA) populations are documented. This study aimed at assessing the prognostic value of the Ankle Brachial Index (ABI) among older adults in the Republic of Congo. METHODS:Congolese ... Read more >>

Atherosclerosis (Atherosclerosis)
[2019, 286:121-127]

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Left Atrial Dynamics in Mitral Regurgitation: When Exercise Runs to the (Left Atrial) Buffers.

Julien Magne, Victor Aboyans,

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2019, :]

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Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

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BACKGROUND:Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders. ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2019, 18(5):459-480]

Cited: 1 time

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The role of ventricular-arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseases, European Association of Cardiovascular Imaging, and Heart Failure Association.

Ignatios Ikonomidis, Victor Aboyans, Jacque Blacher, Marianne Brodmann, Dirk L Brutsaert, Julio A Chirinos, Marco De Carlo, Victoria Delgado, Patrizio Lancellotti, John Lekakis, Dania Mohty, Petros Nihoyannopoulos, John Parissis, Damiano Rizzoni, Frank Ruschitzka, Petar Seferovic, Eugenio Stabile, Dimitrios Tousoulis, Dragos Vinereanu, Charalambos Vlachopoulos, Dimitrios Vlastos, Panagiotis Xaplanteris, Reuven Zimlichman, Marco Metra,

Ventricular-arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment possesses independent diagnostic and prognostic value and may be used to refine riskstratification and monitor therapeutic interventions. Traditionally, VAC is assessed by the non-invasive ... Read more >>

Eur. J. Heart Fail. (European journal of heart failure)
[2019, 21(4):402-424]

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Steno-Stiffness Approach for Cardiovascular Disease Risk Assessment in Primary Prevention.

Hirofumi Tomiyama, Toshiaki Ohkuma, Toshiharu Ninomiya, Chisa Mastumoto, Kazuomi Kario, Satoshi Hoshide, Yoshikuni Kita, Toyoshi Inoguchi, Yasutaka Maeda, Katsuhiko Kohara, Yasuharu Tabara, Motoyuki Nakamura, Takayoshi Ohkubo, Hirotaka Watada, Masanori Munakata, Mitsuru Ohishi, Norihisa Ito, Michinari Nakamura, Tetsuo Shoji, Charalambos Vlachopoulos, Victor Aboyans, Akira Yamashina, ,

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2019, 73(3):508-513]

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The year 2018 in cardiology: aorta and peripheral circulation.

Victor Aboyans, Mislav Vrsalovic, Juraj Madaric, Lucia Mazzolai, Marco De Carlo, ,

Eur. Heart J. (European heart journal)
[2019, 40(11):872-879]

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Antithrombotic Therapy in Lower Extremity Artery Disease.

Mislav Vrsalovic, Victor Aboyans,

Lower extremity artery disease (LEAD) is a marker of a more advanced atherosclerotic process often affecting multiple vascular beds beyond the lower limbs, with a consequent increased risk for all-cause and cardiovascular mortality. Antithrombotic therapy is the cornerstone of management of these patients to prevent ischaemic cardiovascular and limb events ... Read more >>

Curr Vasc Pharmacol (Current vascular pharmacology)
[2019, :]

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Stroke Outcomes in the COMPASS Trial.

Mukul Sharma, Robert G Hart, Stuart J Connolly, Jackie Bosch, Olga Shestakovska, Kelvin K H Ng, Luciana Catanese, Katalin Keltai, Victor Aboyans, Marco Alings, Jong-Won Ha, John Varigos, Andrew Tonkin, Martin O'Donnell, Deepak L Bhatt, Keith Fox, Aldo Maggioni, Scott D Berkowitz, Nancy Cook Bruns, Salim Yusuf, John W Eikelboom,

BACKGROUND:Strokes were significantly reduced by the combination of rivaroxaban plus aspirin in comparison with aspirin in the COMPASS trial (Cardiovascular Outcomes for People Using Anticoagulation Strategies). We present detailed analyses of stroke by type, predictors, and antithrombotic effects in key subgroups. METHODS:Participants had stable coronary artery or peripheral artery disease ... Read more >>

Circulation (Circulation)
[2019, 139(9):1134-1145]

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Management of Patients with Asymptomatic and Symptomatic Carotid Artery Disease: Update on Anti-Thrombotic Therapy.

Daniele Pastori, John W Eikelboom, Sonia S Anand, Manesh Raman Patel, Jean-Francois Tanguay, Jean-Baptiste Ricco, Eike Sebastian Debus, Lucia Mazzolai, Rupert Bauersachs, Peter Verhamme, Jackie Bosch, Sigrid Nikol, Mark Nehler, Victor Aboyans, Francesco Violi,

The most common causes of ischaemic stroke are represented by carotid artery atherosclerotic disease (CAAD) and atrial fibrillation. While oral anticoagulants substantially reduce the incidence of thromboembolic stroke (< 1%/year), the rate of ischaemic stroke and other cardiovascular disease events in patients with CAAD remains high, ranging from 8.4 to ... Read more >>

Thromb. Haemost. (Thrombosis and haemostasis)
[2019, 119(4):576-585]

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Aspirin in people with diabetes: Time to clean up the prescription list?

Julien Vouillarmet, Victor Aboyans,

The effect of aspirin in primary cardiovascular (CV) prevention in people with diabetes is still a matter of debate. Recent results of ASCEND trial suggest that the absolute benefit on CV events is largely counter-balanced by the bleeding risk. However, one crucial question is whether aspirin should be maintained or ... Read more >>

Diabetes Res. Clin. Pract. (Diabetes research and clinical practice)
[2019, 149:208-209]

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Epidemiology of coronary artery disease and stroke and associated risk factors in Gaza community -Palestine.

Amal Jamee Shahwan, Yehia Abed, Ileana Desormais, Julien Magne, Pierre Marie Preux, Victor Aboyans, Philippe Lacroix,

AIM OF STUDY:To determine the prevalence of cardiovascular disease and associated risk factors in the population of Gaza strip in Palestine. METHODS:A cross-sectional stratified cluster sample design was applied in this study. A sample of 2240 participant (1121 males and 1119 females) aged ≥25 years participated in the study. For ... Read more >>

PLoS ONE (PloS one)
[2019, 14(1):e0211131]

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Diagnosis and management of acute deep vein thrombosis: a joint consensus document from the European Society of Cardiology working groups of aorta and peripheral vascular diseases and pulmonary circulation and right ventricular function.

Lucia Mazzolai, Victor Aboyans, Walter Ageno, Giancarlo Agnelli, Adriano Alatri, Rupert Bauersachs, Marjolein P A Brekelmans, Harry R Büller, Antoine Elias, Dominique Farge, Stavros Konstantinides, Gualtiero Palareti, Paolo Prandoni, Marc Righini, Adam Torbicki, Charalambos Vlachopoulos, Marianne Brodmann,

Eur. Heart J. (European heart journal)
[2018, 39(47):4208-4218]

Cited: 7 times

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Left ventricular assessment in patients with systemic light chain amyloidosis: a 3-dimensional speckle tracking transthoracic echocardiographic study.

Sarah Pradel, Julien Magne, Arnaud Jaccard, Bahaa M Fadel, Cyrille Boulogne, Vera Maria Cury Salemi, Thibaud Damy, Victor Aboyans, Dania Mohty,

Cardiac involvement in systemic light chain (AL) amyloidosis carries a poor prognosis mainly through involvement of the left ventricular (LV) myocardium. Despite its limitations, two-dimensional transthoracic echocardiography (2D-TTE) remains the main tool used for the assessment of LV systolic function in AL patients. We hypothesize that 3D-TTE coupled with speckle ... Read more >>

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2019, 35(5):845-854]

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[2018 ESC/ESH Guidelines for the management of arterial hypertension].

Bryan Williams, Giuseppe Mancia, Wilko Spiering, Enrico Agabiti Rosei, Michel Azizi, Michel Burnier, Denis L Clement, Antonio Coca, Giovanni de Simone, Anna Dominiczak, Thomas Kahan, Felix Mahfoud, Josep Redon, Luis Ruilope, Alberto Zanchetti, Mary Kerins, Sverre E Kjeldsen, Reinhold Kreutz, Stephane Laurent, Gregory Y H Lip, Richard McManus, Krzysztof Narkiewicz, Frank Ruschitzka, Roland E Schmieder, Evgeny Shlyakhto, Costas Tsioufis, Victor Aboyans, Ileana Desormais,

Kardiol Pol (Kardiologia polska)
[2019, 77(2):71-159]

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2018 ESC/EACTS Guidelines on myocardial revascularization.

Miguel Sousa-Uva, Franz-Josef Neumann, Anders Ahlsson, Fernando Alfonso, Adrian P Banning, Umberto Benedetto, Robert A Byrne, Jean-Philippe Collet, Volkmar Falk, Stuart J Head, Peter Jüni, Adnan Kastrati, Akos Koller, Steen D Kristensen, Josef Niebauer, Dimitrios J Richter, Petar M Seferovic, Dirk Sibbing, Giulio G Stefanini, Stephan Windecker, Rashmi Yadav, Michael O Zembala, ,

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2019, 55(1):4-90]

Cited: 7 times

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Fourth universal definition of myocardial infarction (2018).

Kristian Thygesen, Joseph S Alpert, Allan S Jaffe, Bernard R Chaitman, Jeroen J Bax, David A Morrow, Harvey D White, ,

Eur. Heart J. (European heart journal)
[2019, 40(3):237-269]

Cited: 12 times

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2018 ESC/EACTS Guidelines on myocardial revascularization.

Franz-Josef Neumann, Miguel Sousa-Uva, Anders Ahlsson, Fernando Alfonso, Adrian P Banning, Umberto Benedetto, Robert A Byrne, Jean-Philippe Collet, Volkmar Falk, Stuart J Head, Peter Jüni, Adnan Kastrati, Akos Koller, Steen D Kristensen, Josef Niebauer, Dimitrios J Richter, Petar M Seferovic, Dirk Sibbing, Giulio G Stefanini, Stephan Windecker, Rashmi Yadav, Michael O Zembala, ,

Eur. Heart J. (European heart journal)
[2019, 40(2):87-165]

Cited: 24 times

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Local carotid arterial stiffness is an independent determinant of left ventricular remodeling in never-treated hypertensive patients.

Olga Vriz, Julien Magne, Joanna Jarosh, Eduardo Bossone, Victor Aboyans, Paolo Palatini,

PURPOSE:The aim was to investigate the association between blood pressure (BP), carotid stiffness, carotid-femoral pulse wave velocity (cfPWV) and left ventricular (LV) remodeling in never-treated hypertensive patients. MATERIAL AND METHODS:178 never-treated hypertensive underwent transthoracic echocardiography, 24-hour ambulatory BP monitoring (ABPM), local carotid stiffness and regional cfPWV assessed using a high-definition ... Read more >>

Blood Press. (Blood pressure)
[2019, 28(1):23-33]

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Mid- and long-term prognosis of off- vs. on-pump coronary artery bypass graft in patients with multisite artery disease.

Louis Le Bivic, Julien Magne, Jean-David Blossier, Alessandro Piccardo, Hélène Wojtyna, Philippe Lacroix, Dania Mohty, Elisabeth Cornu, Alexandre Le Guyader, Victor Aboyans,

BACKGROUND:Among patients with coronary artery disease (CAD), around 25% have multisite artery disease (MSAD). Patients with CAD and MSAD are at higher risk of peri-operative and long-term cardiovascular events. Whether off-pump coronary bypass grafting (CABG) can improve their prognosis is unknown. We aimed to assess the benefits of off- vs. ... Read more >>

J Cardiovasc Surg (Torino) (The Journal of cardiovascular surgery)
[2019, 60(3):388-395]

Cited: 0 times

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The intrinsic prognostic value of the ankle-brachial index is independent from its mode of calculation.

Louis Le Bivic, Julien Magne, Benoit Guy-Moyat, Hélène Wojtyna, Philippe Lacroix, Jean-David Blossier, Alexandre Le Guyader, Iléana Desormais, Victor Aboyans,

The object of this study was to compare the prognostic value of different methods of ankle-brachial index (ABI) calculation. From April 1998 to September 2008, we calculated the ABI in 1223 patients before coronary artery bypass grafting. The ABI was calculated according to five different calculation modes of the numerator. ... Read more >>

Vasc Med (Vascular medicine (London, England))
[2019, 24(1):23-31]

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2018 Practice Guidelines for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension.

Bryan Williams, Giuseppe Mancia, Wilko Spiering, Enrico Agabiti Rosei, Michel Azizi, Michel Burnier, Denis Clement, Antonio Coca, Giovanni De Simone, Anna Dominiczak, Thomas Kahan, Felix Mahfoud, Josep Redon, Luis Ruilope, Alberto Zanchetti, Mary Kerins, Sverre Kjeldsen, Reinhold Kreutz, Stéphane Laurent, Gregory Y H Lip, Richard McManus, Krzysztof Narkiewicz, Frank Ruschitzka, Roland Schmieder, Evgeny Shlyakhto, Konstantinos Tsioufis, Victor Aboyans, Ileana Desormais,

These practice guidelines on the management of arterial hypertension are a concise summary of the more extensive ones prepared by the Task Force jointly appointed by the European Society of Hypertension and the European Society of Cardiology. These guidelines have been prepared on the basis of the best available evidence ... Read more >>

Blood Press. (Blood pressure)
[2018, 27(6):314-340]

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