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Kidney health for everyone everywhere-from prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of ... Read more >>

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2020, 35(10):1801-1810]

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The Association of dp-ucMGP with Cardiovascular Morbidity and Decreased Renal Function in Diabetic Chronic Kidney Disease.

Stefanos Roumeliotis, Athanasios Roumeliotis, Aikaterini Stamou, Konstantinos Leivaditis, Konstantia Kantartzi, Stylianos Panagoutsos, Vassilios Liakopoulos,

We aimed to investigate the possible association of the inactive, dephosphorylated, uncarboxylated matrix Gla protein (dp-ucMGP) with oxidized low-density lipoprotein (ox-LDL) and all-cause/cardiovascular (CV) mortality and renal function in diabetic chronic kidney disease (CKD). Ox-LDL and dp-ucMGP were determined in 66 diabetic CKD patients. All patients were prospectively followed for ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(17):]

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The Association of dp-ucMGP with Cardiovascular Morbidity and Decreased Renal Function in Diabetic Chronic Kidney Disease

Stefanos Roumeliotis, Athanasios Roumeliotis, Aikaterini Stamou, Konstantinos Leivaditis, Konstantia Kantartzi, Stylianos Panagoutsos, Vassilios Liakopoulos,

We aimed to investigate the possible association of the inactive, dephosphorylated, uncarboxylated matrix Gla protein (dp-ucMGP) with oxidized low-density lipoprotein (ox-LDL) and all-cause/cardiovascular (CV) mortality and renal function in diabetic chronic kidney disease (CKD). Ox-LDL and dp-ucMGP were determined in 66 diabetic CKD patients. All patients were prospectively followed for ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(17):]

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Tracking hydration status changes by bioimpedance spectroscopy in children on peritoneal dialysis.

Vasiliki Karava, Stella Stabouli, John Dotis, Vassilios Liakopoulos, Fotios Papachristou, Nikoleta Printza,

BACKGROUND:This 6-month prospective longitudinal study investigates the association between hydration status changes using bioimpedance spectroscopy (BIS) and systolic blood pressure (SBP), pulse pressure (PP), and serum albumin (sAlb) changes in children on peritoneal dialysis (PD). METHODS:Thirteen patients (median age: 12.58 years) were enrolled. Normal hydration, moderate hydration, severe overhydration, and ... Read more >>

Perit Dial Int (Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis)
[2020, :896860820945813]

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Association between relative fat mass, uric acid, and insulin resistance in children with chronic kidney disease.

Vasiliki Karava, John Dotis, Antonia Kondou, Athanasios Christoforidis, Vassilios Liakopoulos, Konstantina Tsioni, Konstantinos Kollios, Fotios Papachristou, Nikoleta Printza,

INTRODUCTION:This cross-sectional study investigates the association between insulin resistance (IR) and serum uric acid (sUA) and relative fat (RFM) and lean mass (RLM) profiles in children with chronic kidney disease (CKD). MATERIAL AND METHODS:RLM and RFM were assessed by bioimpedance spectroscopy in 41 children and adolescents. Normal weight obesity (NWO) ... Read more >>

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2020, :]

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Correction to: Kidney health for everyone everywhere: from prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

The copyright of the article has been incorrectly published. ... Read more >>

J. Nephrol. (Journal of nephrology)
[2020, 33(4):867]

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The association of interdialytic blood pressure variability with cardiovascular events and all-cause mortality in haemodialysis patients.

Pantelis A Sarafidis, Charalampos Loutradis, Antonios Karpetas, Georgios Tzanis, Athanasios Bikos, Vassilios Raptis, Christos Syrgkanis, Vassilios Liakopoulos, Aikaterini Papagianni, George Bakris, Gianfranco Parati,

Nephrol. Dial. Transplant. (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2020, 35(7):1277]

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Prevalence and control of hypertension among patients on haemodialysis.

Nikolaos Tsikliras, Panagiotis I Georgianos, Vasilios Vaios, Elias Minasidis, Aggelina Anagnostara, Christos Chatzidimitriou, Christos Syrganis, Vassilios Liakopoulos, Pantelis E Zebekakis, Elias V Balaskas,

BACKGROUND:Earlier studies provided considerably variable estimates on the prevalence and control rates of hypertension in haemodialysis because of their heterogeneity in definitions and blood pressure (BP) measurement techniques applied to detect hypertension. MATERIALS AND METHODS:In this cross-sectional study, 116 clinically stable haemodialysis patients from 3 dialysis centres of Northern Greece ... Read more >>

Eur. J. Clin. Invest. (European journal of clinical investigation)
[2020, 50(10):e13292]

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Mistimed H2S upregulation, Nrf2 activation and antioxidant proteins levels in renal tubular epithelial cells subjected to anoxia and reoxygenation.

Theodoros Eleftheriadis, Georgios Pissas, Evdokia Nikolaou, Georgios Filippidis, Vassilios Liakopoulos, Ioannis Stefanidis,

Ischemia-reperfusion (I-R) injury is involved in the pathogenesis of several human diseases. In the present study, the kinetics of the H2S producing enzymes-nuclear factor erythroid 2-like 2 (Nrf2)-antioxidant proteins axis under anoxia or reoxygenation was evaluated, as well as its effects on survival of mouse renal proximal tubular epithelial cells ... Read more >>

Biomed Rep (Biomedical reports)
[2020, 13(2):3]

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Reprint of: Kidney health for everyone everywhere-from prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

Nephrol. Ther. (Nephrologie & therapeutique)
[2020, 16(4):211-216]

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Eating during the Hemodialysis Session: A Practice Improving Nutritional Status or a Risk Factor for Intradialytic Hypotension and Reduced Dialysis Adequacy?

Eleni Fotiadou, Panagiotis I Georgianos, Michail Chourdakis, Pantelis E Zebekakis, Vassilios Liakopoulos,

Historically, eating during the hemodialysis treatment has been associated with increased risk for adverse intradialytic symptoms and events, risks that have resulted in the implementation of restrictive in-center nutrition policies. Recent studies, however, have recorded a shift in clinical practice with a higher proportion of physicians following the view that ... Read more >>

Nutrients (Nutrients)
[2020, 12(6):]

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Vascular Calcification in Chronic Kidney Disease: The Role of Vitamin K- Dependent Matrix Gla Protein.

Stefanos Roumeliotis, Evangelia Dounousi, Marios Salmas, Theodoros Eleftheriadis, Vassilios Liakopoulos,

Arterial calcification is highly prevalent in chronic kidney disease (CKD) patients and is associated with cardiovascular (CV) morbidity and mortality. Patients at early CKD stages are more likely to suffer a fatal CV event than to develop end-stage renal disease and require hemodialysis treatment. The heavy CV burden of these ... Read more >>

Front Med (Lausanne) (Frontiers in medicine)
[2020, 7:154]

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Unfavorable Effects of Peritoneal Dialysis Solutions on the Peritoneal Membrane: The Role of Oxidative Stress.

Stefanos Roumeliotis, Evangelia Dounousi, Marios Salmas, Theodoros Eleftheriadis, Vassilios Liakopoulos,

One of the main limitations to successful long-term use of peritoneal dialysis (PD) as a renal replacement therapy is the harmful effects of PD solutions to the structure and function of the peritoneal membrane (PM). In PD, the PM serves as a semipermeable membrane that, due to exposure to PD ... Read more >>

Biomolecules (Biomolecules)
[2020, 10(5):]

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Biomarkers of vascular calcification in serum.

Stefanos Roumeliotis, Athanasios Roumeliotis, Evangelia Dounousi, Theodoros Eleftheriadis, Vassilios Liakopoulos,

Over the last decades, the association between vascular calcification (VC) and all-cause/cardiovascular mortality, especially in patients with high atherogenic status, such as those with diabetes and/or chronic kidney disease, has been repeatedly highlighted. For over a century, VC has been noted as a passive, degenerative, aging process without any treatment ... Read more >>

Adv Clin Chem (Advances in clinical chemistry)
[2020, 98:91-147]

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A unifying model of glucotoxicity in human renal proximal tubular epithelial cells and the effect of the SGLT2 inhibitor dapagliflozin.

Theodoros Eleftheriadis, Georgios Pissas, Konstantina Tsogka, Evdokia Nikolaou, Vassilios Liakopoulos, Ioannis Stefanidis,

BACKGROUND:Glucotoxicity in renal tubular epithelial cells (RPTECs) contributes to the pathogenesis of diabetic nephropathy. Sodium-glucose cotransporter 2 (SGLT2) inhibitors may exert their renoprotective effect by preventing glucotoxicity. We tested whether the confirmed in capillary endothelial cells unifying model of glucotoxicity can be applied in RPTECs and the impact of dapagliflozin. ... Read more >>

Int Urol Nephrol (International urology and nephrology)
[2020, 52(6):1179-1189]

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10-year-long survival in a PD patient with severe calcifying encapsulating peritoneal sclerosis treated with tamoxifen: a case-report.

Vassilios Liakopoulos, Panagiotis I Georgianos, Vasilios Vaios, Stefanos Roumeliotis, Apostolos Karligkiotis, Pantelis E Zebekakis,

BACKGROUND:Encapsulating-peritoneal-sclerosis (EPS) is a rare, but serious and life-threatening complication of peritoneal dialysis (PD). Treatment of EPS consists of discontinuation of PD and maintenance of nutritional status, whereas the role of corticosteroids, tamoxifen and other immunosuppresive agents is not yet fully elucidated. CASE-PRESENTATION:We report the case of a 28-year-old patient, ... Read more >>

BMC Nephrol (BMC nephrology)
[2020, 21(1):110]

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Kidney health for everyone everywhere: from prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of ... Read more >>

J. Nephrol. (Journal of nephrology)
[2020, 33(2):201-210]

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Blood pressure targets in patients with chronic kidney disease: A critical evaluation of clinical-trial evidence and guideline recommendations.

Panagiotis I Georgianos, Vasilios Vaios, Pantelis E Zebekakis, Vassilios Liakopoulos,

J Clin Hypertens (Greenwich) (Journal of clinical hypertension (Greenwich, Conn.))
[2020, 22(5):924-928]

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Thrombophilia in hemodialysis patients: Transfer to peritoneal dialysis is life saving.

Athanasios Roumeliotis, Vasilios Vaios, Fotios Girtovitis, Apostolos Karligkiotis, Konstantinos Leivaditis, Pantelis Zebekakis, Vassilios Liakopoulos,

The majority of vascular access thrombosis episodes in hemodialysis patients are due to anatomic abnormalities. Thrombophilias are inherited, acquired or mixed disorders which also predispose to venous thromboembolism. They include protein C, protein S and antithrombin deficiencies, as well as gene mutations for prothrombin and factor V Leiden. The most ... Read more >>

Semin Dial (Seminars in dialysis)
[2020, 33(4):338-342]

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Pulse wave velocity assessment for cardiovascular risk prognostication in ESKD: weighing recent evidence.

Panagiotis I Georgianos, Vasilios Vaios, Theodoros Eleftheriadis, Pantelis E Zebekakis, Vassilios Liakopoulos,

Among patients with end-stage kidney disease (ESKD), arterial stiffness is considered as a powerful predictor of cardiovascular (CV) morbidity and mortality. However, the relevance of aortic pulse wave velocity (PWV) as a prognostic biomarker for CV risk estimation is not yet fully clear. We performed a systematic search of Medline/PubMed ... Read more >>

Curr Vasc Pharmacol (Current vascular pharmacology)
[2020, :]

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Kidney Health for Everyone Everywhere - From Prevention to Detection and Equitable Access to Care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh,

The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of ... Read more >>

Kidney Dis (Basel) (Kidney Diseases)
[2020, 6(3):136-143]

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Unexpected restoration of an arteriovenous graft function: the significance of vascular access surveillance.

Theodoros Eleftheriadis, Christos Rountas, Georgios Karagiorgas, Vassilios Liakopoulos, Ioannis Stefanidis,

CEN Case Rep (CEN case reports)
[2020, 9(3):291-293]

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Kidney Health for Everyone, Everywhere-from prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

Nephrol. Dial. Transplant. (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2020, 35(3):367-374]

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Kidney health for everyone everywhere - from prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh,

Chronic kidney disease (CKD) is rapidly becoming the 5th most common cause of years of life lost globally by 2040. Crucially, the onset and progression of CKD is often preventable. The World Kidney Day 2020 campaign highlights the importance of preventive interventions on CKD. Primary prevention should focus on risks ... Read more >>

Arch Argent Pediatr (Archivos argentinos de pediatria)
[2020, 118(2):e148]

Cited: 1 time

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Kidney Health for Everyone Everywhere - From prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, , ,

The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of ... Read more >>

Nefrologia (Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia)
[2020, 40(2):133-141]

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