Full Text Journal Articles by
Author V E Murphy

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Rhinovirus bronchiolitis, maternal asthma, and the development of asthma and lung function impairments.

Carla R Da Silva Sena, Matthew Morten, Joseph Meredith, Elizabeth Kepreotes, Vanessa E Murphy, Peter G Gibson, Paul D Robinson, Peter D Sly, Bruce Whitehead, Wilfried Karmaus, Adam Collison, Joerg Mattes,

<h4>Background</h4>Children with a history of rhinovirus (RV) positive bronchiolitis have a high risk of developing subsequent asthma. Maternal asthma might also increase this risk. The aim of this study was to investigate the combined effects of hospitalization for RV positive bronchiolitis in infancy and a history of maternal asthma on ... Read more >>

Pediatr Pulmonol (Pediatric pulmonology)
[2021, 56(2):362-370]

Cited: 0 times

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Maternal asthma and gestational diabetes mellitus: Exploration of potential associations.

M E Jensen, H L Barrett, M J Peek, P G Gibson, V E Murphy,

Asthma and gestational diabetes mellitus are prevalent during pregnancy and associated with adverse perinatal outcomes. The risk of gestational diabetes mellitus is increased with asthma, and more severe asthma; yet, the underlying mechanisms are unknown. This review examines existing literature to explore possible links.  Asthma and gestational diabetes mellitus are ... Read more >>

Obstet Med (Obstetric medicine)
[2021, 14(1):12-18]

Cited: 0 times

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People with intellectual disabilities and the COVID-19 pandemic.

G Gulati, E Fistein, C P Dunne, B D Kelly, V E Murphy,

Ir J Psychol Med (Irish journal of psychological medicine)
[2021, 38(2):158-159]

Cited: 1 time

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Vitamin D status in pregnant women with asthma and its association with adverse respiratory outcomes during infancy.

Megan E Jensen, V E Murphy, P G Gibson, J Mattes, C A Camargo,

BACKGROUND:Vitamin D may influence pregnancy and infant outcomes, especially infant respiratory health. This study aimed to examine vitamin D status in pregnant women with asthma, and whether higher vitamin D levels are associated with fewer adverse respiratory outcomes in their infants. METHODS:Pregnant women with asthma, recruited from John Hunter Hospital ... Read more >>

J Matern Fetal Neonatal Med (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2019, 32(11):1820-1825]

Cited: 2 times

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The risk of congenital malformations, perinatal mortality and neonatal hospitalisation among pregnant women with asthma: a systematic review and meta-analysis.

V E Murphy, G Wang, J A Namazy, H Powell, P G Gibson, C Chambers, M Schatz,

<h4>Background</h4>There is conflicting literature on the effect of maternal asthma on congenital malformations and neonatal outcomes.<h4>Objectives</h4>This review and meta-analysis sought to determine if maternal asthma is associated with an increased risk of adverse neonatal outcomes.<h4>Search strategy</h4>We searched electronic databases for: (asthma or wheeze) and (pregnan* or perinat* or obstet*).<h4>Selection criteria</h4>Cohort ... Read more >>

BJOG (BJOG : an international journal of obstetrics and gynaecology)
[2013, 120(7):812-822]

Cited: 47 times

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A meta-analysis of adverse perinatal outcomes in women with asthma.

V E Murphy, J A Namazy, H Powell, M Schatz, C Chambers, J Attia, P G Gibson,

<h4>Background</h4>Asthma is a common condition during pregnancy and may be associated with adverse perinatal outcomes.<h4>Objective</h4>This meta-analysis sought to establish if maternal asthma is associated with an increased risk of adverse perinatal outcomes, and to determine the size of these effects.<h4>Search strategy</h4>Electronic databases were searched for the following terms: (asthma or ... Read more >>

BJOG (BJOG : an international journal of obstetrics and gynaecology)
[2011, 118(11):1314-1323]

Cited: 113 times

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Asthma exacerbations during pregnancy: incidence and association with adverse pregnancy outcomes.

V E Murphy, V L Clifton, P G Gibson,

Exacerbations of asthma during pregnancy represent a significant clinical problem and may be related to poor pregnancy outcomes. A systematic review of the literature was conducted for publications related to exacerbations during pregnancy. Four studies with a control group (no asthma) and two groups of women with asthma (exacerbation, no ... Read more >>

Thorax (Thorax)
[2006, 61(2):169-176]

Cited: 141 times

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Asthma self-management skills and the use of asthma education during pregnancy.

V E Murphy, P G Gibson, P I Talbot, C G Kessell, V L Clifton,

During pregnancy, patients with asthma are at risk of poor outcomes, particularly when asthma is poorly controlled. The aim of this study was to determine the level of asthma self-management skills and knowledge among pregnant subjects and describe the implementation of an asthma education programme delivered in an antenatal clinic ... Read more >>

Eur Respir J (The European respiratory journal)
[2005, 26(3):435-441]

Cited: 38 times

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Asthma during pregnancy: mechanisms and treatment implications.

V E Murphy, P G Gibson, R Smith, V L Clifton,

Asthma is becoming increasingly prevalent worldwide. Numerous historical and prospective cohort studies have investigated the effects of maternal asthma on pregnancy outcome; however, the data has been conflicting and many studies have not used standard classifications for asthma severity. Overall, the literature suggests that asthmatic females are more at risk ... Read more >>

Eur Respir J (The European respiratory journal)
[2005, 25(4):731-750]

Cited: 65 times

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Maternal asthma as a model for examining fetal sex-specific effects on maternal physiology and placental mechanisms that regulate human fetal growth.

V L Clifton, V E Murphy,

Studying the effect of maternal asthma during pregnancy on placental function and fetal development has highlighted that there is a strong interaction between mother, placenta and fetus and these interactions appear to be sex-specific. This work has found that the female fetus alters maternal asthma during pregnancy by upregulating maternal ... Read more >>

Placenta (Placenta)
[2004, 25 Suppl A:S45-52]

Cited: 77 times

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Alterations in human placental 11beta-hydroxysteroid dehydrogenase type 1 and 2 with gestational age and labour.

V E Murphy, V L Clifton,

11beta-hydroxysteroid dehydrogenase type 1 and type 2 may be important in the process of human parturition and the regulation of fetal growth, by the modulation of cortisol concentrations in the fetal compartment. Changes in the expression and activity of these enzymes in late gestation have not been well described. This ... Read more >>

Placenta (Placenta)
[2003, 24(7):739-744]

Cited: 78 times

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Search for bipolar disorder susceptibility loci: the application of a modified genome scan concentrating on gene-rich regions.

V E Murphy, L A Mynett-Johnson, E Claffey, P Bergin, M McAuliffe, C Kealey, P McKeon,

Conducting genome wide screens for evidence of genetic linkage has become a well-established method for identifying regions of the human genome harboring susceptibility loci for complex disorders. For bipolar disorder, a number of such studies have been performed, and several regions of the genome have potentially been implicated in the ... Read more >>

Am J Med Genet (American journal of medical genetics)
[2000, 96(6):728-732]

Cited: 10 times

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Preliminary evidence of an association between bipolar disorder in females and the catechol-O-methyltransferase gene.

L A Mynett-Johnson, V E Murphy, E Claffey, D C Shields, P McKeon,

Catechol-O-methyltransferase (COMT) catalyses the methylation, and hence the inactivation, of catecholamines including the neurotransmitters dopamine and noradrenaline. There is evidence implicating COMT as a candidate gene for a number of neuropsychiatric conditions including bipolar disorder. A long recognized population variation in COMT activity exists and it has recently been established ... Read more >>

Psychiatr Genet (Psychiatric genetics)
[1998, 8(4):221-225]

Cited: 49 times

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