Full Text Journal Articles by
Author Tsugunobu Andoh

Advertisement

Find full text journal articles






Overexpression of D-dopachrome tautomerase increases ultraviolet B irradiation-induced skin tumorigenesis in mice.

Yoko Yoshihisa, Mati Ur Rehman, Tsugunobu Andoh, Yoshiaki Tabuchi, Teruhiko Makino, Tadamichi Shimizu,

Ultraviolet irradiation (UV) exposure is the leading factor underlying the development of skin malignancies. D-dopachrome tautomerase (D-DT), a functional homolog of macrophage migration inhibitory factor (MIF), has functional similarities to MIF. However, its role, unlike the role of MIF in photocarcinogenesis, is unknown. We therefore explored the role of D-DT ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(7):e21671]

Cited: 0 times

View full text PDF listing >>



Berberine induces anti-atopic dermatitis effects through the downregulation of cutaneous EIF3F and MALT1 in NC/Nga mice with atopy-like dermatitis.

Tsugunobu Andoh, Yoko Yoshihisa, Mati Ur Rehman, Yoshiaki Tabuchi, Tadamichi Shimizu,

Atopic dermatitis (AD) is a chronic inflammatory skin disease with severe pruritus. Berberine, a naturally occurring isoquinoline alkaloid, has anti-inflammatory effects. This study investigated the effects and molecular mechanisms of berberine on AD-like symptoms in mice. In this study, NC/Nga mice with atopy-like dermatitis (dermatitis mice), fibroblast and mast cells ... Read more >>

Biochem Pharmacol (Biochemical pharmacology)
[2021, 185:114439]

Cited: 0 times

View full text PDF listing >>



Advertisement

Inhibitory effect of panaxytriol on BV-2 microglial cell activation.

Genki Hiramatsu, Daisuke Uta, Kenichi Mihara, Tsugunobu Andoh, Toshiaki Kume,

Activated microglia induce brain inflammation and neuronal death. Panaxytriol, ((3R,9R,10R)-Heptadec-1-en-4,6-diyne-3,9,10-triol), is a component of Panax ginseng C. A. Meyer extracts and activates the Nrf2-ARE signaling pathway. However, little is known about its effects on activated microglia in the brain. In this study, we investigated the effect of panaxytriol on lipopolysaccharide ... Read more >>

J Pharmacol Sci (Journal of pharmacological sciences)
[2021, 145(3):273-278]

Cited: 0 times

View full text PDF listing >>



Iridoids isolated from Viticis Fructus inhibit paclitaxel-induced mechanical allodynia in mice.

Huanhuan Yu, Kazufumi Toume, Yoko Kurokawa, Tsugunobu Andoh, Katsuko Komatsu,

Chemotherapy-induced peripheral neuropathy (CIPN) manifests as mechanical allodynia and hyperalgesia, and is one of the main adverse effects of chemotherapeutic agents. Currently available therapeutic drugs are not sufficiently effective for the management of this adverse effect in the clinic. Therefore, the development of novel therapeutic agents for treating CIPN is ... Read more >>

J Nat Med (Journal of natural medicines)
[2021, 75(1):48-55]

Cited: 0 times

View full text PDF listing >>



Correction to: Search of anti-allodynic compounds from Plantaginis Semen, a crude drug ingredient of Kampo formula "Goshajinkigan".

Kazufumi Toume, Zhiyan Hou, Huanhuan Yu, Mitsuru Kato, Miki Maesaka, Yanjing Bai, Shiho Hanazawa, Yuewei Ge, Tsugunobu Andoh, Katsuko Komatsu,

The article Search of anti-allodynic compounds from Plantaginis Semen, a crude drug ingredient of Kampo formula "Goshajinkigan". ... Read more >>

J Nat Med (Journal of natural medicines)
[2020, 74(3):615]

Cited: 0 times

View full text PDF listing >>



Inhibitory effect of amenamevir on acute herpetic pain and postherpetic neuralgia in mice infected with herpes simplex virus-1.

Yuhki Ueda, Daisuke Uta, Soichiro Tanbo, Akiko Kawabata, Shoji Kanayama, Miho Osaki, Naoki Nozawa, Tatsumi Matsumoto, Tsugunobu Andoh,

<h4>Background</h4>Amenamevir (AMNV) is a helicase-primase inhibitor with antiviral activity against herpesviruses [herpes simplex viruses (HSV)-1 and -2, and varicella-zoster virus], which are associated with the development of acute herpetic pain (AHP) and postherpetic neuralgia. However, the inhibitory effects of helicase-primase inhibitors on AHP and postherpetic neuralgia remain incompletely understood.<h4>Objective</h4>In this ... Read more >>

J Dermatol Sci (Journal of dermatological science)
[2020, 98(1):50-57]

Cited: 0 times

View full text PDF listing >>



Gardenia Fruit-Related Blue-Gray Skin Pigmentation.

Megumi Mizawa, Tsugunobu Andoh, Tadamichi Shimizu,

JAMA Dermatol (JAMA dermatology)
[2020, 156(3):351-353]

Cited: 0 times

View full text PDF listing >>



Pharmacological Characterization of a Novel Mouse Model of Cholestatic Pruritus.

Tsugunobu Andoh, Kazunari Suzuki, Mitsuhiro Konno, Koichi Tsuneyama, Yasushi Kuraishi,

Patients with cholestatic liver diseases, such as primary biliary cirrhosis, usually suffer from pruritus. However, the pathogenesis of cholestatic pruritus is unclear, and there is no current effective treatment for it. In order to find a treatment for the condition, an appropriate mouse model should be developed. Therefore, here, we ... Read more >>

Biol Pharm Bull (Biological & pharmaceutical bulletin)
[2020, 43(7):1111-1117]

Cited: 0 times

View full text PDF listing >>



Neuronal hyperexcitability and astrocyte activation in spinal dorsal horn of a dermatitis mouse model with cutaneous hypersensitivity.

Yoshihiro Inami, Daisuke Uta, Tsugunobu Andoh,

Cleaning products such as soaps, shampoos, and detergents are comprised mainly of surfactants, agents known to cause dermatitis and cutaneous hypersensitivity characterized by itching, stinging, and burning of the skin and scalp. However, the mechanisms underlying surfactant-induced cutaneous hypersensitivity remain unclear. In the present study, we investigated the mechanisms of ... Read more >>

Neurosci Lett (Neuroscience letters)
[2020, 720:134784]

Cited: 0 times

View full text PDF listing >>



The regulation of protein kinase casein kinase II by apigenin is involved in the inhibition of ultraviolet B-induced macrophage migration inhibitory factor-mediated hyperpigmentation.

Yoko Yoshihisa, Tsugunobu Andoh, Mati Ur Rehman, Tadamichi Shimizu,

Ultraviolet (UV) radiation elicits melanogenesis and pigmentation in the skin. Apigenin (4',5,7-trihydroxyflavone [AGN]) is a plant flavone contained in various herbs, fruits, and vegetables. We herein investigated antimelanogenic properties of AGN and the molecular mechanisms of the action of AGN. In UVB-treated mice, AGN inhibited cutaneous hyperpigmentation and macrophage migration ... Read more >>

Phytother Res (Phytotherapy research : PTR)
[2020, 34(6):1320-1328]

Cited: 0 times

View full text PDF listing >>



Selective role of neurokinin B in IL-31-induced itch response in mice.

Daiji Sakata, Takehito Uruno, Keisuke Matsubara, Tsugunobu Andoh, Kazuhiko Yamamura, Yuki Magoshi, Kazufumi Kunimura, Yasuhisa Kamikaseda, Masutaka Furue, Yoshinori Fukui,

J Allergy Clin Immunol (The Journal of allergy and clinical immunology)
[2019, 144(4):1130-1133.e8]

Cited: 4 times

View full text PDF listing >>



Involvement of α-Melanocyte-Stimulating Hormone-Thromboxane A2 System on Itching in Atopic Dermatitis.

Tsugunobu Andoh, Chihiro Akasaka, Kyoko Shimizu, Jung-Bum Lee, Yoko Yoshihisa, Tadamichi Shimizu,

α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone involved in cutaneous pigmentation in atopic dermatitis (AD) with severe itching. α-MSH elicits itch-related responses in mice. We, therefore, investigated whether α-MSH was involved in itching in AD. In the skin of AD patients and mice with atopy-like dermatitis, α-MSH and the ... Read more >>

Am J Pathol (The American journal of pathology)
[2019, 189(9):1775-1785]

Cited: 2 times

View full text PDF listing >>



Search of anti-allodynic compounds from Plantaginis Semen, a crude drug ingredient of Kampo formula "Goshajinkigan".

Kazufumi Toume, Zhiyan Hou, Huanhuan Yu, Mitsuru Kato, Miki Maesaka, Yanjing Bai, Shiho Hanazawa, Yuewei Ge, Tsugunobu Andoh, Katsuko Komatsu,

Chemotherapy-induced peripheral neuropathy (CIPN) is one of the dose-limiting side effects of cancer chemotherapy. Although the control of CIPN is important, it is difficult to manage with currently available therapeutic drugs. Therefore, there is a need for novel therapeutic agents for treating CIPN. Goshajinkigan (GJG) is a Kampo formula composed ... Read more >>

J Nat Med (Journal of natural medicines)
[2019, 73(4):761-768]

Cited: 4 times

View full text PDF listing >>



Mechanisms of itching in mycosis fungoides: grade of itching correlates with eosinophil infiltration and kallikrein 5 expression.

Kyoko Shimizu, Tsugunobu Andoh, Teruhiko Makino, Yoko Yoshihisa, Megumi Mizawa, Tadamichi Shimizu,

<h4>Background</h4>Mycosis fungoides (MF) is the most common variant of cutaneous T-cell lymphomas (CTCL). Itching can be a major symptom for patients with CTCL, however, itching associated with MF is not relieved by conventional therapy using anti-histamines, suggesting that histamine is not the main pruritogen. Therefore, the underlying mechanisms of itching ... Read more >>

Eur J Dermatol (European journal of dermatology : EJD)
[2019, 29(3):268-273]

Cited: 1 time

View full text PDF listing >>



Prophylactic Repetitive Treatment with the Herbal Medicine Kei-kyoh-zoh-soh-oh-shin-bu-toh Attenuates Oxaliplatin-Induced Mechanical Allodynia by Decreasing Spinal Astrocytes.

Tsugunobu Andoh, Daisuke Fukutomi, Daisuke Uta, Yasushi Kuraishi,

Chemotherapeutic drugs typically induce peripheral neuropathy, which is a major dose-limiting side effect of these drugs and is difficult to manage. In this study, we examined whether the traditional herbal formulation Kei-kyoh-zoh-soh-oh-shin-bu-toh (KSOT) could relieve the mechanical allodynia induced by chemotherapeutic drugs (oxaliplatin, paclitaxel, vincristine, and bortezomib) in mice. A ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2019, 2019:4029694]

Cited: 0 times

View full text PDF listing >>



Animal models of chronic pain increase spontaneous glutamatergic transmission in adult rat spinal dorsal horn in vitro and in vivo.

Daisuke Uta, Go Kato, Atsushi Doi, Tsugunobu Andoh, Toshiaki Kume, Megumu Yoshimura, Kohei Koga,

The ability to detect noxious stimulation is essential to an organism's survival and wellbeing. Chronic pain is characterized by abnormal sensitivity to normal stimulation coupled with a feeling of unpleasantness. This condition afflicts people worldwide and severely impacts their quality of life and has become an escalating health problem. The ... Read more >>

Biochem Biophys Res Commun (Biochemical and biophysical research communications)
[2019, 512(2):352-359]

Cited: 2 times

View full text PDF listing >>



Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells.

Sailesh Palikhe, Wakana Ohashi, Takuya Sakamoto, Kohshi Hattori, Masaaki Kawakami, Tsugunobu Andoh, Hiromi Yamazaki, Yuichi Hattori,

G protein-coupled receptor kinase 2 (GRK2) is a ubiquitous member of the GRK family that restrains cellular activation by G protein-coupled receptor (GPCR) phosphorylation leading to receptor desensitization and internalization, but has been identified to regulate a variety of signaling molecules, among which may be associated with inflammation. In this ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2019, 10:59]

Cited: 0 times

View full text PDF listing >>



Enlarging the irradiation spot to include the edge of hyperkeratotic papules using a CO2 surgical laser dramatically improves the treatment of lichen amyloidosus.

Ko Kagoyama, Tsugunobu Andoh, Tadamichi Shimizu,

Eur J Dermatol (European journal of dermatology : EJD)
[2018, 28(6):837-839]

Cited: 0 times

View full text PDF listing >>



β2-Microglobulin, interleukin-31, and arachidonic acid metabolites (leukotriene B4 and thromboxane A2) are involved in chronic renal failure-associated itch-associated responses in mice.

Sikai Li, Tsugunobu Andoh, Qun Zhang, Daisuke Uta, Yasushi Kuraishi,

Chronic renal failure (CRF) is a progressive disease with severe pruritus and dry skin as the major symptoms. However, the mechanisms of CRF-induced pruritus remain unclear. In this study, 5/6 nephrectomized (NPCT) mice were used as a mouse model of CRF. Serum concentrations of blood urea nitrogen and creatinine in ... Read more >>

Eur J Pharmacol (European journal of pharmacology)
[2019, 847:19-25]

Cited: 1 time

View full text PDF listing >>



Role of P2X3 receptors in scratching behavior in mouse models.

Miho Shiratori-Hayashi, Ayumi Hasegawa, Honami Toyonaga, Tsugunobu Andoh, Takeshi Nakahara, Makiko Kido-Nakahara, Masutaka Furue, Yasushi Kuraishi, Kazuhide Inoue, Xinzhong Dong, Makoto Tsuda,

J Allergy Clin Immunol (The Journal of allergy and clinical immunology)
[2019, 143(3):1252-1254.e8]

Cited: 0 times

View full text PDF listing >>



Remifentanil suppresses increase in interleukin-6 mRNA in the brain by inhibiting cyclic AMP synthesis.

Shigeru Maeda, Tsugunobu Andoh, Rieko Onishi, Yumiko Tomoyasu, Hitoshi Higuchi, Takuya Miyawaki,

<h4>Purpose</h4>Neuronal inflammation is caused by systemic inflammation and induces cognitive dysfunction. IL-6 plays a crucial role in therapies for neuronal inflammation and cognitive dysfunction. Remifentanil, an ultra-short-acting opioid, controls inflammatory reactions in the periphery, but not in the brain. Therefore, the anti-inflammatory effects of remifentanil in neuronal tissue and the ... Read more >>

J Anesth (Journal of anesthesia)
[2018, 32(5):731-739]

Cited: 2 times

View full text PDF listing >>



Analgesic effects of systemic fentanyl on cancer pain are mediated by not only central but also peripheral opioid receptors in mice.

Akira Shinohara, Tsugunobu Andoh, Ikuo Saiki, Yasushi Kuraishi,

Fentanyl is an opioid commonly prescribed for cancer pain. Using melanoma-bearing mice, we investigated whether peripheral action would contribute to fentanyl analgesia in cancer pain. Intravenous injection of fentanyl inhibited mechanical nociception in healthy mice, which was markedly inhibited by the opioid antagonist naloxone, but not naloxone methiodide, a peripherally ... Read more >>

Eur J Pharmacol (European journal of pharmacology)
[2018, 833:275-282]

Cited: 3 times

View full text PDF listing >>



Peripheral gabapentin regulates mosquito allergy-induced itch in mice.

Tasuku Akiyama, Tsugunobu Andoh, Eiji Ohtsuka, Hiroshi Nojima, Hidekazu Ouchi, Hiroki Takahata, Yasushi Kuraishi,

The antipruritic activity of gabapentin, an anticonvulsant, was studied in a mouse model of allergic itch. In mice sensitized by an extract of the salivary glands of the mosquito (ESGM), an intradermal injection of ESGM elicited scratching and increased peripheral nerve firing. Oral or intradermal administration of gabapentin at the ... Read more >>

Eur J Pharmacol (European journal of pharmacology)
[2018, 833:44-49]

Cited: 0 times

View full text PDF listing >>



Non-myelinated C-fibers, but not myelinated A-fibers, elongate into the epidermis in dry skin with itch.

Tsugunobu Andoh, Yuta Asakawa, Yasushi Kuraishi,

Chronic skin diseases with itch and dry skin show increased peripheral nerve fiber elongation into the epidermis. However, the characteristics of the elongated nerve fibers remain unclear. Therefore, we investigated the characteristics of the elongated nerve fibers using a dry skin mouse model with itch. In this mouse model, prepared ... Read more >>

Neurosci Lett (Neuroscience letters)
[2018, 672:84-89]

Cited: 0 times

View full text PDF listing >>



Involvement of thromboxane A2 in interleukin-31-induced itch-associated response in mice.

Tsugunobu Andoh, Sikai Li, Daisuke Uta,

BACKGROUND:Atopic dermatitis is a chronic and severe pruritic skin disease. Interlukin-31 (IL-31) has been recently demonstrated to be one of the key pruritogens in atopic dermatitis. However, the mechanisms underlying IL-31-induced itching remains unclear. In our previous study, we have shown that thromboxane (TX) A2 is involved in itch-associated responses ... Read more >>

Pharmacol Rep (Pharmacological reports : PR)
[2018, 70(2):251-257]

Cited: 1 time

View full text PDF listing >>



Advertisement

Disclaimer
1.1854 s