Full Text Journal Articles by
Author Tristan M Nicholson

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Women in Leadership in Urology: The Case for Increasing Diversity and Equity.

Jennifer Chyu, Chloe E Peters, Tristan M Nicholson, Jessica C Dai, Jennifer Taylor, Tullika Garg, Angela B Smith, Sima P Porten, Kirsten Greene, Nicole Browning, Elaine Harris, Suzette E Sutherland, Sarah P Psutka,

There is a persistent male gender predominance in urology, especially with respect to female representation in leadership. We review the current status of women in urology leadership, discuss challenges women face in leadership positions, present the case for adopting inclusive practices that increase diversity and gender equity in urology leadership, ... Read more >>

Urology (Urology)
[2020, :]

Cited: 0 times

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Nephrolithiasis in Pregnancy: Treating for Two.

Jessica C Dai, Tristan M Nicholson, Helena C Chang, Alana C Desai, Robert M Sweet, Jonathan D Harper, Mathew D Sorensen,

Symptomatic nephrolithiasis affects less than 1% of all pregnancies but poses unique risks to both mother and fetus. Diagnostic imaging in this population is challenging due to physiologic changes of pregnancy and concerns regarding fetal ionizing radiation exposure. Ultrasound remains the imaging modality of choice. Most patients can be managed ... Read more >>

Urology (Urology)
[2020, :]

Cited: 0 times

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Injection molded open microfluidic well plate inserts for user-friendly coculture and microscopy.

John H Day, Tristan M Nicholson, Xiaojing Su, Tammi L van Neel, Ivor Clinton, Anbarasi Kothandapani, Jinwoo Lee, Max H Greenberg, John K Amory, Thomas J Walsh, Charles H Muller, Omar E Franco, Colin R Jefcoate, Susan E Crawford, Joan S Jorgensen, Ashleigh B Theberge,

Open microfluidic cell culture systems are powerful tools for interrogating biological mechanisms. We have previously presented a microscale cell culture system, based on spontaneous capillary flow of biocompatible hydrogels, that is integrated into a standard cell culture well plate, with flexible cell compartment geometries and easy pipet access. Here, we ... Read more >>

Lab Chip (Lab on a chip)
[2020, 20(1):107-119]

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Tissue-specific quantification and localization of androgen and estrogen receptors in prostate cancer.

Priyanka D Sehgal, Tyler M Bauman, Tristan M Nicholson, Jordan E Vellky, Emily A Ricke, Weiping Tang, Wei Xu, Wei Huang, William A Ricke,

Androgens and estrogens, working together, promote prostate cancer (PRCA) initiation and progression, with androgens acting via androgen receptor (AR) and estrogens acting primarily through estrogen receptor α (ERα). While the interplay between these steroid hormones has been established, the interaction between steroid hormone receptors in prostatic disease remains unstudied. The ... Read more >>

Hum Pathol (Human pathology)
[2019, 89:99-108]

Cited: 3 times

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Endocrine disruptor bisphenol A is implicated in urinary voiding dysfunction in male mice.

Tristan M Nicholson, Jalissa L Nguyen, Glen E Leverson, Julia A Taylor, Frederick S Vom Saal, Ronald W Wood, William A Ricke,

Estrogens, acting synergistically with androgens, are known from animal experiments to be important in lower urinary tract symptoms (LUTS) and benign prostate enlargement. Human exposure to environmental estrogens occurs throughout the life span, but the urologic health risks in men are largely unknown. Bisphenol A (BPA) is an endocrine disruptor ... Read more >>

Am. J. Physiol. Renal Physiol. (American journal of physiology. Renal physiology)
[2018, 315(5):F1208-F1216]

Cited: 3 times

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Estrogens and Male Lower Urinary Tract Dysfunction.

Jalissa L Wynder, Tristan M Nicholson, Donald B DeFranco, William A Ricke,

Benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms (LUTS) are common clinical problems in urology and affect the majority of men at some time during their lives. The development of BPH/LUTS is associated with an increased ratio of estrogen to androgen levels, and this ratio, when mimicked in ... Read more >>

Curr Urol Rep (Current urology reports)
[2015, 16(9):61]

Cited: 5 times

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Characterization of fibrillar collagens and extracellular matrix of glandular benign prostatic hyperplasia nodules.

Tyler M Bauman, Tristan M Nicholson, Lisa L Abler, Kevin W Eliceiri, Wei Huang, Chad M Vezina, William A Ricke,

Recent studies have associated lower urinary tract symptoms (LUTS) in men with prostatic fibrosis, but a definitive link between collagen deposition and LUTS has yet to be demonstrated. The objective of this study was to evaluate ECM and collagen content within normal glandular prostate tissue and glandular BPH, and to ... Read more >>

PLoS One (PloS one)
[2014, 9(10):e109102]

Cited: 34 times

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Renal capsule xenografting and subcutaneous pellet implantation for the evaluation of prostate carcinogenesis and benign prostatic hyperplasia.

Tristan M Nicholson, Kristen S Uchtmann, Conrad D Valdez, Ashleigh B Theberge, Tihomir Miralem, William A Ricke,

New therapies for two common prostate diseases, prostate cancer (PrCa) and benign prostatic hyperplasia (BPH), depend critically on experiments evaluating their hormonal regulation. Sex steroid hormones (notably androgens and estrogens) are important in PrCa and BPH; we probe their respective roles in inducing prostate growth and carcinogenesis in mice with ... Read more >>

J Vis Exp (Journal of visualized experiments : JoVE)
[2013, (78):]

Cited: 4 times

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Sex steroid receptor expression and localization in benign prostatic hyperplasia varies with tissue compartment.

Tristan M Nicholson, Priyanka D Sehgal, Sally A Drew, Wei Huang, William A Ricke,

Androgens and estrogens, acting via their respective receptors, are important in benign prostatic hyperplasia (BPH). The goals of this study were to quantitatively characterize the tissue distribution and staining intensity of androgen receptor (AR) and estrogen receptor-alpha (ERα), and assess cells expressing both AR and ERα, in human BPH compared ... Read more >>

Differentiation (Differentiation; research in biological diversity)
[2013, 85(4-5):140-149]

Cited: 36 times

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Testosterone and 17β-estradiol induce glandular prostatic growth, bladder outlet obstruction, and voiding dysfunction in male mice.

Tristan M Nicholson, Emily A Ricke, Paul C Marker, Joseph M Miano, Robert D Mayer, Barry G Timms, Frederick S vom Saal, Ronald W Wood, William A Ricke,

Benign prostatic hyperplasia (BPH) and bladder outlet obstruction (BOO) are common in older men and can contribute to lower urinary tract symptoms that significantly impact quality of life. Few existing models of BOO and BPH use physiological levels of hormones associated with disease progression in humans in a genetically manipulable ... Read more >>

Endocrinology (Endocrinology)
[2012, 153(11):5556-5565]

Cited: 51 times

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Pelvic angiomyolipoma.

Tristan M Nicholson, Granville L Lloyd, Guan Wu,

Angiomyolipoma is a rare benign tumor most commonly found in the kidney and, infrequently, extrarenally. We report a case of pelvic angiomyolipoma in a male patient without stigmata of tuberous sclerosis. The patient presented with right retroperitoneal bleeding and was found to have bilateral renal angiomyolipomas as well as a ... Read more >>

Urology (Urology)
[2012, 79(2):e15-6]

Cited: 1 time

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Androgens and estrogens in benign prostatic hyperplasia: past, present and future.

Tristan M Nicholson, William A Ricke,

Benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms (LUTS) are common clinical problems in urology. While the precise molecular etiology remains unclear, sex steroids have been implicated in the development and maintenance of BPH. Sufficient data exists linking androgens and androgen receptor pathways to BPH and use of ... Read more >>

Differentiation (Differentiation; research in biological diversity)
[2011, 82(4-5):184-199]

Cited: 103 times

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