Full Text Journal Articles by
Author Tonya S King

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Biomarkers to Predict Response to ICS and LAMA in Adolescents and Adults with Mild Persistent Asthma.

Jerry A Krishnan, Stephen C Lazarus, Kathryn V Blake, Christine A Sorkness, Ronina Covar, Anne-Marie Dyer, Jason E Lang, Njira L Lugogo, David T Mauger, Michael E Wechsler, Sally E Wenzel, Juan Carlos Cardet, Mario Castro, Elliot Israel, Wanda Phipatanakul, Tonya S King, ,

Rationale Whether biomarkers can be used to predict response to inhaled corticosteroids (ICS) or long-acting muscarinic antagonists (LAMA) in mild persistent asthma is unclear. Objectives In a pre-specified exploratory analysis of a randomized clinical trial of 295 participants >12 years old with uncontrolled mild persistent asthma, we sought to identify ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2021, :]

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Rethinking physical activity assessment in cancer survivors: a multi-component approach using NHANES data.

Shirley M Bluethmann, Sarah K Keadle, Tonya S King, Charles E Matthews, Frank M Perna,

<h4>Purpose</h4>To confirm that a multi-component physical activity index (PAI), with physical activity (PA)-related behaviors and performance measures, enhances PA assessment for adults with cancer history ("survivors") vs. for the general population for key health variables.<h4>Methods</h4>Data from 2011 to 2014 NHANES were analyzed (n = 9620 adults, including 866 survivors). We ... Read more >>

J Cancer Surviv (Journal of cancer survivorship : research and practice)
[2021, :]

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Recovery Characteristics in Neonates Following General Anesthesia: A Retrospective Chart Review.

David Fanelli, Daniel Kim, Tonya S King, Gregory E Weller, Priti G Dalal,

Introduction Preterm babies increasingly survive the neonatal period as a result of advanced care practices. Accordingly, anesthesiologists are likely to encounter these patients with greater frequency. Ex-premature infants and term neonates are known to have an increased risk of post-operative apneas following surgery and anaesthesia. Methods Following approval from the Institutional Review Board, ... Read more >>

Cureus (Cureus)
[2021, 13(7):e16126]

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The effect of prescribing antibiotics with opioids on the development of opioid use disorder: a national database study.

Zachary G Freedman, Jennifer A Kane, Tonya S King, Nicholas M Graziane,

The goal of this study was to examine the impact of inpatient- or emergency department- prescribed antibiotic treatment in combination with opioids on the risk of developing opioid use disorder 12 months following discharge from the hospital. The authors conducted a propensity score-matched cohort study with data from the TriNetX Research ... Read more >>

J Addict Dis (Journal of addictive diseases)
[2021, :1-13]

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The Depiction of Medical Errors in a Sample of Medical Television Shows.

Molly Carney, Tonya S King, Anna Yumen, Carissa Harnish-Cruz, Renyta Scales, Robert P Olympia,

<h4>Background</h4>Medical errors and adverse events may affect up to 7.5% of hospitalizations, although observational studies suggest the numbers could be even higher. Previous studies have shown that medical television (TV) shows may be a major driver when it comes to a patient's medical knowledge and perspectives.<h4>Methods</h4>Six episodes from the first ... Read more >>

Cureus (Cureus)
[2020, 12(12):e11994]

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Outcomes following quadriceps tendon repair using transosseous tunnels versus suture anchors: A systematic review.

Anuj V Mehta, Christopher Wilson, Tonya S King, Robert A Gallo,

<h4>Introduction</h4>Two major techniques are used to repair complete quadriceps tendon ruptures, transosseous tunnel (TT) and the suture anchor (SA). There are multiple studies comparing the biomechanical outcomes of repairs performed with TT or SA. Our purpose was to compare the clinical outcomes following quadriceps tendon repair using SA and TT ... Read more >>

Injury (Injury)
[2021, 52(3):339-344]

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Outpatient Sistrunk procedure: A retrospective analysis.

Christopher Pool, Mattie Rosi-Schumacher, Christopher Ehret, Tonya S King, Meghan N Wilson,

<h4>Objective</h4>The risk of expansile hematoma and airway compromise following neck surgery have been used to validate overnight observation. We investigated the outcomes of pediatric patients undergoing a Sistrunk procedure via either same day surgery or overnight observation.<h4>Methods</h4>A retrospective review of patients undergoing Sistrunk procedures between January 1, 2008 to January ... Read more >>

Int J Pediatr Otorhinolaryngol (International journal of pediatric otorhinolaryngology)
[2020, 139:110455]

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T3 versus T4a staging challenges in deeply invasive colonic adenocarcinomas and correlation with clinical outcomes.

Robert Pantaleon Vasquez, Mustafa Erdem Arslan, Hwajeong Lee, Tonya S King, Deepti Dhall, Dipti M Karamchandani,

Despite the latest 8th edition American Joint Committee on Cancer Staging Manual guidelines, disagreement still exists among pathologists regarding staging deeply invasive colonic adenocarcinomas ≤1 mm to the serosal surface. In this retrospective study, 151 untreated colonic adenocarcinomas staged initially as either pT3 or pT4a and with available 5-year follow-up data ... Read more >>

Mod Pathol (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2021, 34(1):131-140]

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Themes in Superhero-Based Television Shows: An Opportunity for the Development of Children and Adolescents Through Co-Viewing and Active Mediation.

Raymond Y Kim, Morgan K Moroi, Amalia Brawley, Marian Poley, Tonya S King, Robert Olympia,

The depiction of superheroes and comic book characters in television shows has become incredibly popular. The objective of this study was to determine the positive and negative themes depicted in a select number of superhero-based television shows. A total of 49 episodes from 10 superhero-based television shows were analyzed by ... Read more >>

Cureus (Cureus)
[2020, 12(5):e7965]

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Intervention Design and Trial Protocol: Mindfulness-based Exposure for PAP-associated Claustrophobia.

Michael J Gawrysiak, Michael Baime, Tonya S King, Alexa J Watach, Miranda V McPhillips, Ann Kolanowski, Sharon Schutte-Rodin, Amy M Sawyer,

Positive airway pressure (PAP) associated claustrophobia is common among obstructive sleep apnea patients and plays a prominent role in low adherence and treatment failure. As there are no evidence-based interventions for PAP-associated claustrophobia, the objective of the present research is to pilot test Mindfulness-based Exposure for PAP-associated Claustrophobia, in sleep ... Read more >>

West J Nurs Res (Western journal of nursing research)
[2021, 43(3):261-272]

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The relationship between diurnal variation of cytokines and symptom expression in mild obstructive sleep apnea.

Hyunju Yang, Christopher G Engeland, Tonya S King, Amy M Sawyer,

<h4>Objectives</h4>To identify the relationship between (1) cytokines and everyday symptoms and (2) cytokine diurnal variation and everyday symptoms in mild obstructive sleep apnea (OSA).<h4>Methods</h4>An observational, single-night study of 20 adults with mild to moderate OSA undergoing diagnostic polysomnography. Everyday symptoms included sleepiness measured by Stanford Sleepiness Scale, fatigue and energy ... Read more >>

J Clin Sleep Med (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine)
[2020, 16(5):715-723]

Cited: 1 time

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Themes Depicted in Top-grossing Rated-R Films Released from 2012 to 2017.

Andrew Watts, Justin Loloi, Kaila Lessner, Marina Mizell, Katherine Shoemaker, Tonya S King, Robert Olympia,

INTRODUCTION:Films continue to be a popular form of entertainment amongst children and adolescents. The objective of this study was to determine the most common themes depicted in a select number of rated-R films released 2012-2017. METHODS:A total of 25 films were independently viewed and analyzed by five reviewers. RESULTS:The most ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6844]

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A Comparison of Transesophageal to Transthoracic Echocardiographic Measures of Right Ventricular Function.

Shayne Michael Roberts, John Klick, Adrian Fischl, Tonya S King, Theodore J Cios,

<h4>Objectives</h4>To assess the concordance between transesophageal echocardiographic (TEE) and transthoracic echocardiograpic (TTE) measures of right ventricular (RV) function using standard 2-dimensional and Doppler methods. The authors hypothesized that there would be significant disagreement in tricuspid annular plane systolic excursion (TAPSE), fractional area change, right-sided index of myocardial performance, and tricuspid ... Read more >>

J Cardiothorac Vasc Anesth (Journal of cardiothoracic and vascular anesthesia)
[2020, 34(5):1252-1259]

Cited: 1 time

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Violence Depicted in Superhero-Based Films Stratified by Protagonist/Antagonist and Gender.

John N Muller, Annie Moroco, Justin Loloi, Austin Portolese, Bryan H Wakefield, Tonya S King, Robert Olympia,

The objective of this study was to describe and quantify acts of violence depicted in a select number of superhero-based films, further stratified by protagonist/antagonist characters and gender. A total of 10 superhero-based films released in 2015-2016 were analyzed by five independent reviewers. The average number of acts of violence ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6843]

Cited: 1 time

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CHA2DS2-VASc Score and In-Hospital Mortality in Critically Ill Patients With New-Onset Atrial Fibrillation.

Kunal Karamchandani, Robert S Schoaps, Thomas Abendroth, Zyad J Carr, Tonya S King, Anthony Bonavia,

<h4>Objective</h4>To examine the role of the CHA<sub>2</sub>DS<sub>2</sub>-VASc (Congestive heart failure; Hypertension; Age ≥75 years [doubled]; Diabetes; previous Stroke, transient ischemic attack, or thromboembolism [doubled]; Vascular disease; Age 65-75 years; and Sex category) score as a prognostic marker of in-hospital mortality in critically ill patients who develop new-onset atrial fibrillation (NOAF).<h4>Design</h4>Retrospective ... Read more >>

J Cardiothorac Vasc Anesth (Journal of cardiothoracic and vascular anesthesia)
[2020, 34(5):1165-1171]

Cited: 1 time

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Exacerbation-prone asthma in the context of race and ancestry in Asthma Clinical Research Network trials.

Nicole L Grossman, Victor E Ortega, Tonya S King, Eugene R Bleecker, Elizabeth A Ampleford, Leonard B Bacharier, Michael D Cabana, Juan C Cardet, Tara F Carr, Mario Castro, Loren C Denlinger, Joshua L Denson, Nicolas Fandino, Anne M Fitzpatrick, Gregory A Hawkins, Fernando Holguin, Jerry A Krishnan, Stephen C Lazarus, Sharmilee M Nyenhuis, Wanda Phipatanakul, Sima K Ramratnam, Sally Wenzel, Stephen P Peters, Deborah A Meyers, Michael E Wechsler, Elliot Israel,

<h4>Background</h4>Minority groups of African descent experience disproportionately greater asthma morbidity compared with other racial groups, suggesting that genetic variation from a common ancestry could influence exacerbation risk.<h4>Objective</h4>We evaluated clinical trial measures in the context of self-reported race and genetic ancestry to identify risk factors for asthma exacerbations.<h4>Methods</h4>One thousand eight hundred ... Read more >>

J Allergy Clin Immunol (The Journal of allergy and clinical immunology)
[2019, 144(6):1524-1533]

Cited: 5 times

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Challenges with colorectal cancer staging: results of an international study.

Dipti M Karamchandani, Runjan Chetty, Tonya S King, Xiuli Liu, Maria Westerhoff, Zhaohai Yang, Rhonda K Yantiss, David K Driman,

Challenges exist with standardized colorectal cancer reporting despite adoption of the American Joint Committee on Cancer-Staging Manual 8th edition. We performed this study to gauge current practice patterns among a diverse group of surgical pathologists. A web-based questionnaire depicting problematic issues and images related to colorectal carcinoma staging was circulated ... Read more >>

Mod Pathol (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2020, 33(1):153-163]

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Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level.

Stephen C Lazarus, Jerry A Krishnan, Tonya S King, Jason E Lang, Kathryn V Blake, Ronina Covar, Njira Lugogo, Sally Wenzel, Vernon M Chinchilli, David T Mauger, Anne-Marie Dyer, Homer A Boushey, John V Fahy, Prescott G Woodruff, Leonard B Bacharier, Michael D Cabana, Juan C Cardet, Mario Castro, James Chmiel, Loren Denlinger, Emily DiMango, Anne M Fitzpatrick, Deborah Gentile, Annette Hastie, Fernando Holguin, Elliot Israel, Daniel Jackson, Monica Kraft, Craig LaForce, Robert F Lemanske, Fernando D Martinez, Wendy Moore, Wayne J Morgan, James N Moy, Ross Myers, Stephen P Peters, Wanda Phipatanakul, Jacqueline A Pongracic, Loretta Que, Kristie Ross, Lewis Smith, Stanley J Szefler, Michael E Wechsler, Christine A Sorkness, ,

BACKGROUND:In many patients with mild, persistent asthma, the percentage of eosinophils in sputum is less than 2% (low eosinophil level). The appropriate treatment for these patients is unknown. METHODS:In this 42-week, double-blind, crossover trial, we assigned 295 patients who were at least 12 years of age and who had mild, ... Read more >>

N Engl J Med (The New England journal of medicine)
[2019, 380(21):2009-2019]

Cited: 22 times

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Themes Depicted in Running-Related Films: An Opportunity for Co-Viewing and Active Mediation.

Abigail Nelson, Kelly Patterson, Andrew Groff, Tonya S King, Jodi Brady, Robert P Olympia,

Sport participation is an important part of the development of children and adolescents. The objective of this study was to identify and quantify themes depicted in a select number of running-related films. Thirty-one running-related films were independently viewed and analyzed by 4 reviewers. The number of positive and negative themes ... Read more >>

Clin Pediatr (Phila) (Clinical pediatrics)
[2019, 58(7):778-788]

Cited: 0 times

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Intraoperative aberrometry versus preoperative biometry for intraocular lens power selection in short eyes.

Shruti Sudhakar, Darren C Hill, Tonya S King, Ingrid U Scott, Gautam Mishra, Brett B Ernst, Seth M Pantanelli,

<h4>Purpose</h4>To compare the accuracy of preoperative biometry-based formulas to intraoperative aberrometry (IA) with respect to predicting refractive outcomes after cataract surgery in short eyes.<h4>Setting</h4>Private practice and community-based ambulatory surgery center.<h4>Design</h4>Retrospective consecutive case series.<h4>Methods</h4>Eyes with an axial length (AL) shorter than 22.1 mm underwent cataract extraction and intraocular lens (IOL) implantation. The ... Read more >>

J Cataract Refract Surg (Journal of cataract and refractive surgery)
[2019, 45(6):719-724]

Cited: 4 times

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Positive and Negative Themes Depicted in Combat-Related Sports Films.

Andrew Watts, Christy Lucas, Eric Brzozowski, Zachary Winthrop, Tonya S King, Robert P Olympia,

Participation in boxing, mixed martial arts, and wrestling is extremely popular among children and adolescents. The objective of this study was to determine themes depicted in a select number of combat-related films. Twenty films were independently viewed and analyzed by 4 reviewers. The average number of positive and negative themes ... Read more >>

Glob Pediatr Health (Global pediatric health)
[2019, 6:2333794X19847027]

Cited: 0 times

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Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era.

Christine A Sorkness, Tonya S King, Anne-Marie Dyer, Vernon M Chinchilli, David T Mauger, Jerry A Krishnan, Kathryn Blake, Mario Castro, Ronina Covar, Elliot Israel, Monica Kraft, Jason E Lang, Njira Lugogo, Stephen P Peters, Michael E Wechsler, Sally E Wenzel, Stephen C Lazarus, ,

Precision medicine is expected to impact the care of people with asthma, given its high disease prevalence, heterogeneity of pathophysiologic mechanisms, and consequent clinical phenotypes. A novel phenotype-stratified clinical trial conducted by the NHLBI AsthmaNet Consortium, titled Steroids in Eosinophil Negative Asthma (SIENA), was a randomized, multicenter, clinical trial that ... Read more >>

Contemp Clin Trials (Contemporary clinical trials)
[2019, 77:98-103]

Cited: 1 time

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Predictors of inhaled corticosteroid taper failure in adults with asthma.

Juan Carlos Cardet, Christopher D Codispoti, Tonya S King, Leonard Bacharier, Tara Carr, Mario Castro, Vernon Chinchilli, Ryan Dunn, Fernando Holquing, Linda Engle, Kyle Nelson, Victor E Ortega, Michael Peters, Sima Ramratnam, Jerry A Krishnan, Michael E Wechsler, Elliot Israel, ,

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2019, 7(4):1335-1337.e3]

Cited: 0 times

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Bacterial biogeography of adult airways in atopic asthma.

Juliana Durack, Yvonne J Huang, Snehal Nariya, Laura S Christian, K Mark Ansel, Avraham Beigelman, Mario Castro, Anne-Marie Dyer, Elliot Israel, Monica Kraft, Richard J Martin, David T Mauger, Sharon R Rosenberg, Tonya S King, Steven R White, Loren C Denlinger, Fernando Holguin, Stephen C Lazarus, Njira Lugogo, Stephen P Peters, Lewis J Smith, Michael E Wechsler, Susan V Lynch, Homer A Boushey, ,

<h4>Background</h4>Perturbations to the composition and function of bronchial bacterial communities appear to contribute to the pathophysiology of asthma. Unraveling the nature and mechanisms of these complex associations will require large longitudinal studies, for which bronchoscopy is poorly suited. Studies of samples obtained by sputum induction and nasopharyngeal brushing or lavage ... Read more >>

Microbiome (Microbiome)
[2018, 6(1):104]

Cited: 29 times

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Association of free vitamin D3 concentrations and asthma treatment failures in the VIDA Trial.

John J Lima, Mario Castro, Tonya S King, Jason E Lang, Victor E Ortega, Stephen P Peters, Loren C Denlinger, Elliot Israel, Christine A Sorkness, Michael E Wechsler, Sally E Wenzel, Lewis J Smith,

<h4>Background</h4>Use of vitamin D<sub>3</sub> serum concentrations as a biomarker of vitamin D status is questionable because of variation in vitamin D binding protein.<h4>Objective</h4>To determine associations between free vitamin D3 concentrations and rates of treatment failure and exacerbations in patients with asthma participating in the Vitamin D Add-on Therapy Enhances Corticosteroid ... Read more >>

Ann Allergy Asthma Immunol (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology)
[2018, 121(4):444-450.e1]

Cited: 3 times

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