Full Text Journal Articles by
Author Tong Zhou

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Visualization of crystal plane selectivity for irreversible phase transition in [email protected] anode.

Tong Zhou, Liang Chang, Weiqin Li, Chao Li, Wenjuan Yuan, Cuihua An, Jun Luo,

Transition metal oxides are widely regarded as one of the most promising candidates for lithium-ion battery (LIB) anodes. However, the mechanisms of irreversible reactions occurring during the charging/discharging process are still controversial. In this study, the atomic structural transitions of the [email protected] anode upon lithiation/delithiation at the first cycle of ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(26):3753-3756]

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Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization

Yongcun Qu, Qi Chen, Shanshan Guo, Chiyuan Ma, Yonggang Lu, Junchao Shi, Shichao Liu, Tong Zhou, Taichi Noda, Jingjing Qian, Liwen Zhang, Xili Zhu, Xiaohua Lei, Yujing Cao, Wei Li, Wei Li, Nicolas Plachta, Martin Matzuk, Masahito Ikawa, Enkui Duan, Ying Zhang, Hongmei Wang,

Abstract Sperm cooperation has been observed in multiple species, yet its existence and benefit for reproductive success in mammals remains underexplored. Here, combining tissue-clearing with deep three-dimensional imaging, we demonstrate that postcopulatory mouse sperm congregate into unidirectional sperm cooperative clusters at the utero-tubal junction (UTJ), a key physical barrier for ... Read more >>

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Catalytic hydrolysis of CFC-12 over MoO3/ZrO2 -TiO2 solid acid

Zhiqian Li, Tong Zhou, Guoqing Ren, Xiaofang Tan, Lijuan Jia, Tiancheng Liu,

Abstract The catalytic hydrolysis of Difluorodichloromethane(CFC-12) by solid acid of MoO 3 /ZrO 2 -TiO 2 calcined at different temperature had been studied. The effects of catalytic hydrolysis temperature and water vapor concentration on catalytic hydrolysis of CFC-12were also studied. The results showed that catalytic hydrolysis rate of CFC-12 reached ... Read more >>

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A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2

Qingrui Huang, Kai Ji, Siyu Tian, Fengze Wang, Baoying Huang, Zhou Tong, Shuguang Tan, Junfeng Hao, Qihui Wang, Wenjie Tan, George Fu Gao, Jinghua Yan,

Abstract The rapid expansion of COVID-19 pandemic has made the development of a SARS-CoV-2 vaccine a global health and economic priority. Taking advantages of versatility and rapid development, three SARS-CoV-2 mRNA vaccine candidates has entered clinical trials with a two-dose immunization regimen. However, the waning antibodies response in convalescent patients ... Read more >>

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miR-150 regulates glucose utilization through targeting GLUT4 in insulin-resistant cardiomyocytes.

Jin Ju, Dan Xiao, Nannan Shen, Tong Zhou, Hui Che, Xia Li, Shuqian Zhang, Justine Nyakango Mokembo, Nabanit Kumar Jha, Seth Mikaye Monayo, Zhiguo Wang, Yong Zhang,

MicroRNAs (miRNAs) play an important role in cardiac function and metabolism. However, whether they regulate insulin resistance (IR) of cardiomyocytes remains unclear. The aim of the present study was to shed light on this issue with a focus on miR-150. We found here that miR-150 level was elevated in myocardium ... Read more >>

Acta Biochim Biophys Sin (Shanghai) (Acta biochimica et biophysica Sinica)
[2020, :]

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The phase-change evolution from surface to bulk of MnO anodes upon cycling.

Liang Chang, Dongqi Liu, Tong Zhou, Min Hu, Yuchen Wang, Shangmeng Ge, Jia He, Chao Li, Cuihua An,

Transition-metal oxides with low valence states are promising candidates as anodes for advanced rechargeable Li-ion batteries. Surprisingly, the capacities of such anode materials initially decrease and then increase after long-term cycling. Herein, MnO is selected as a representative material to study the structure-function relationship and elucidate the above-mentioned phenomena during ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(39):20425-20431]

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Analysis of the molecular nature associated with microsatellite status in colon cancer identifies clinical implications for immunotherapy.

Xuanwen Bao, Hangyu Zhang, Wei Wu, Shaobing Cheng, Xiaomeng Dai, Xudong Zhu, Qihan Fu, Zhou Tong, Lulu Liu, Yi Zheng, Peng Zhao, Weijia Fang, Fanglong Liu,

BACKGROUND:Microsatellite instability in colon cancer implies favorable therapeutic outcomes after checkpoint blockade immunotherapy. However, the molecular nature of microsatellite instability is not well elucidated. METHODS:We examined the immune microenvironment of colon cancer using assessments of the bulk transcriptome and the single-cell transcriptome focusing on molecular nature of microsatellite stability (MSS) ... Read more >>

J Immunother Cancer (Journal for immunotherapy of cancer)
[2020, 8(2):]

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Performance of HepaRG and HepG2 cells in the high-throughput micronucleus assay for in vitro genotoxicity assessment.

Xiaoqing Guo, Ji-Eun Seo, Dayton Petibone, Volodymyr Tryndyak, Un Jung Lee, Tong Zhou, Timothy W Robison, Nan Mei,

The micronucleus (MN) assay is a core test used to evaluate genotoxic potential of xenobiotics. The traditional in vitro MN assay is usually conducted in cells lacking metabolic competency or by supplementing cultures with an exogenous rat S9 metabolic system, which creates a significant assay limitation for detecting genotoxic metabolites. ... Read more >>

J Toxicol Environ Health A (Journal of toxicology and environmental health. Part A)
[2020, 83(21-22):702-717]

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Identification of volatile components from oviposition and non-oviposition plants of Gasterophilus pecorum (Diptera: Gasterophilidae).

Ran Zhou, Ke Zhang, Tiange Zhang, Tong Zhou, Hongjun Chu, Yan Ge, Chen Wang, Kai Li,

Oviposition by Gasterophilus pecorum on shoot tips of Stipa caucasica is a key determinant of its severe infection of the reintroduced Przewalski's horse (Equus przewalskii). Volatiles in shoots of grasses on which Przewalski's horse feeds, including S. caucasica at preoviposition, oviposition, and postoviposition stages of G. pecorum, S. caucasica, Stipa ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):15731]

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Unveiling the structural evolution of 1T SnS2 anode upon lithiation/delithiation by TEM.

Ruicong Xie, Ying Cui, Tong Zhou, Junqiang Ren, Longchao Zhuo, Jun Luo, Chao Li, Xizheng Liu,

Herein, the definite structure-dependent evolution process upon lithiation/delithiation and clear atomic images of pure 1T-phase SnS2 were obtained for the first time, illustrating the different insertion-conversion-desertion processes of discharge/charge plateaus. Also, 1T SnS2 exhibited advantages over commercial SnS2 (mixed with 1T and 1H phases) in cell resistance and lithium-storage performance. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2019, 55(54):7800-7803]

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Interventions for Preventing Chemotherapy-Induced Alopecia: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials.

Tong Zhou, Shuyu Han, Zheng Zhu, Yan Hu, Weijie Xing,

BACKGROUND:Chemotherapy-induced alopecia (CIA) is a common adverse effect among patients undergoing chemotherapy. Patients experiencing CIA suffer psychological distress and even refuse or discontinue chemotherapy. A variety of interventions have been applied to prevent CIA. However, the best intervention option remains unknown. OBJECTIVE:To evaluate and determine the comparative effects of all ... Read more >>

Cancer Nurs (Cancer nursing)
[2020, :]

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A COVID-19 descriptive study of life after lockdown in Wuhan, China.

Tong Zhou, Thuy-Vy Thi Nguyen, Jiayi Zhong, Junsheng Liu,

On 8 April 2020, the Chinese government lifted the lockdown and opened up public transportation in Wuhan, China, the epicentre of the COVID-19 pandemic. After 76 days in lockdown, Wuhan residents were allowed to travel outside of the city and go back to work. Yet, given that there is still ... Read more >>

R Soc Open Sci (Royal Society open science)
[2020, 7(9):200705]

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Whole-exome sequencing reveals potential mechanisms of drug resistance to FGFR3-TACC3 targeted therapy and subsequent drug selection: towards a personalized medicine.

Zhou Tong, Cong Yan, Yu-An Dong, Ming Yao, Hangyu Zhang, Lulu Liu, Yi Zheng, Peng Zhao, Yimin Wang, Weijia Fang, Feifei Zhang, Weiqin Jiang,

BACKGROUND:Drug resistance is a major obstacle to effective cancer therapy. In order to detect the change in tumor genomic states under drug selection pressure, we use next-generation sequencing technology to investigate the underlying potential mechanisms of drug resistance. METHODS:In our study, we presented a bladder cancer patient who had been ... Read more >>

BMC Med Genomics (BMC medical genomics)
[2020, 13(1):138]

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Characterization and functional analysis of Krtap11-1 during hair follicle development in Angora rabbits (Oryctolagus cuniculus).

Shuang Liang, Zhiyuan Bao, Bohao Zhao, Tong Zhou, Jiali Li, Ming Liu, Shuaishuai Hu, Naisu Yang, Yang Chen, Xinsheng Wu,

BACKGROUND:Keratin-associated protein (KAP), the structural protein molecule of hair fibers, plays a key role in determining the physical properties of hair. Studies of Krtap11-1 have focused only on its localization. Functional studies of Krtap11-1 in hair follicle development have so far not been reported. OBJECTIVE:This study aimed to provide evidence ... Read more >>

Genes Genomics (Genes & genomics)
[2020, 42(11):1281-1290]

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Insufficient radiofrequency ablation promotes epithelial-mesenchymal transition mediated by interleukin-6/signal transducer and activator of transcription 3/Snail pathway in the H22 cells.

Tong Zhou, Bin Liu, Yongzheng Wang, Wujie Wang, Haiyang Chang, Dong Li, Yuliang Li, Zhaomin Song,

Context:Radiofrequency ablation (RFA), an established and minimally invasive therapy for hepatocellular carcinoma, has become an important treatment strategy. However, tumor aggressiveness remains a common problem. The epithelial-mesenchymal transition (EMT) is thought to play an important role in this process. Design and Aims:Due to limited sample volumes harvested from patients, we ... Read more >>

J Cancer Res Ther (Journal of cancer research and therapeutics)
[2020, 16(5):1112-1118]

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Early-life carbamate exposure and intelligence quotient of seven-year-old children.

Jiming Zhang, Jianqiu Guo, Chunhua Wu, Xiaojuan Qi, Shuai Jiang, Tong Zhou, Hongxi Xiao, Wenting Li, Dasheng Lu, Chao Feng, Weijiu Liang, Xiuli Chang, Yubin Zhang, Yang Cao, Guoquan Wang, Zhijun Zhou,

BACKGROUND:Early-life carbamate exposure during developmental period has been linked with adverse health effects and attracted attention. METHODS:Three hundred and three children at age of seven were included in the current study. Urinary carbofuranphenol concentrations were measured using gas chromatography-tandem mass spectrometry. Verbal, performance and full-scale intelligence quotients (IQV, IQP, and ... Read more >>

Environ Int (Environment international)
[2020, 145:106105]

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Isoleucine attenuates infection induced by E. coli challenge through the modulation of intestinal endogenous antimicrobial peptide expression and the inhibition of the increase in plasma endotoxin and IL-6 in weaned pigs.

Man Ren, Shuang Cai, Tong Zhou, Shihai Zhang, Shenghe Li, Erhui Jin, Chuanyan Che, Xiangfang Zeng, Tao Zhang, Shiyan Qiao,

Enteric infection is a major cause of morbidity and mortality in both humans and animals worldwide. Immunotherapy against intestinal infection is a well-known alternative to the antibiotic strategy. Herein, we demonstrated that isoleucine significantly suppressed the multiplication of E. coli in the presence of IPEC-J2 cells. Isoleucine supplementation enhanced the ... Read more >>

Food Funct (Food & function)
[2019, 10(6):3535-3542]

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Nicotine Promotes WRL68 Cells Proliferation Due to the Mutant p53 Gain-of-Function by Activating CDK6-p53-RS-PIN1-STAT1 Signaling Pathway.

Huai Wang, Lu Chen, Tong Zhou, Zhongwei Zhang, Canwei Zeng,

The liver is an important organ with many tasks, such as dealing with drugs, alcohol and other toxins to remove them from the body. Nicotine is the more abundant component in cigarette smoking, which is first metabolized in liver and increases the risk of developing hepatocellular carcinoma (HCC). Also, genotoxic ... Read more >>

Chem Res Toxicol (Chemical research in toxicology)
[2020, 33(9):2361-2373]

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Small RNA modifications in Alzheimer's disease.

Xudong Zhang, Fatima Trebak, Lucas A C Souza, Junchao Shi, Tong Zhou, Patrick G Kehoe, Qi Chen, Yumei Feng Earley,

Background While significant advances have been made in uncovering the aetiology of Alzheimer's disease and related dementias at the genetic level, molecular events at the epigenetic level remain largely undefined. Emerging evidence indicates that small non-coding RNAs (sncRNAs) and their associated RNA modifications are important regulators of complex physiological and ... Read more >>

Neurobiol Dis (Neurobiology of disease)
[2020, 145:105058]

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The value of lymphocyte count in determining the severity of COVID-19 and estimating the time for nucleic acid test results to turn negative.

Yuanchao Li, Tuoyun Yang, Sicong Wang, Junbo Zheng, Jing Zhou, Min Jiang, Tong Zhou, Yang Cao, Hongliang Wang,

Peripheral blood lymphocyte count is shown to be decreased in patients with COVID-19 in the early stage of the disease. The degree of lymphocyte count reduction is related to COVID-19 severity and could be used as an indicator to reflect the disease severity. Our aim was to investigate the value ... Read more >>

Bosn J Basic Med Sci (Bosnian journal of basic medical sciences)
[2020, :]

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Corrigendum to: "Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing".

Xilin Li, Si Chen, Xiaoqing Guo, Qiangen Wu, Ji-Eun Seo, Lei Guo, Mugimane G Manjanatha, Tong Zhou, Kristine L Witt, Nan Mei,

Toxicol. Sci. (Toxicological sciences : an official journal of the Society of Toxicology)
[2020, :]

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Correction: Isoleucine attenuates infection induced by E. coli challenge through the modulation of intestinal endogenous antimicrobial peptide expression and the inhibition of the increase in plasma endotoxin and IL-6 in weaned pigs.

Man Ren, Shuang Cai, Tong Zhou, Shihai Zhang, Shenghe Li, Erhui Jin, Chuanyan Che, Xiangfang Zeng, Tao Zhang, Shiyan Qiao,

Correction for 'Isoleucine attenuates infection induced by E. coli challenge through the modulation of intestinal endogenous antimicrobial peptide expression and the inhibition of the increase in plasma endotoxin and IL-6 in weaned pigs' by Man Ren et al., Food Funct., 2019, DOI: 10.1039/c9fo00218a. ... Read more >>

Food Funct (Food & function)
[2019, 10(6):3799]

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Discovery of Prognostic Signature Genes for Overall Survival Prediction in Gastric Cancer.

Changyuan Meng, Shusen Xia, Yi He, Xiaolong Tang, Guangjun Zhang, Tong Zhou,

Background:Gastric cancer (GC) is one of the most common malignant tumors in the digestive system with high mortality globally. However, the biomarkers that accurately predict the prognosis are still lacking. Therefore, it is important to screen for novel prognostic markers and therapeutic targets. Methods:We conducted differential expression analysis and survival ... Read more >>

Comput Math Methods Med (Computational and mathematical methods in medicine)
[2020, 2020:5479279]

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Suppression of Helicobacter pylori infection by daily cranberry intake: A double-blind, randomized, placebo-controlled trial.

Zhe-Xuan Li, Jun-Ling Ma, Yang Guo, Wei-Dong Liu, Ming Li, Lan-Fu Zhang, Yang Zhang, Tong Zhou, Jing-Ying Zhang, Ha-Er Gao, Xiao-Ying Guo, Dong-Man Ye, Wen-Qing Li, Wei-Cheng You, Kai-Feng Pan,

BACKGROUND AND AIM:Dietary strategies that contribute to reducing incidence of Helicobacter pylori infection without negative side effects are highly desirable owing to worldwide bacterial prevalence and carcinogenesis potential. The aim of this study was to determine dosage effect of daily cranberry consumption on H. pylori suppression over time in infected adults ... Read more >>

J. Gastroenterol. Hepatol. (Journal of gastroenterology and hepatology)
[2020, :]

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Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines.

Xilin Li, Xiaobo He, Si Chen, Xiaoqing Guo, Matthew S Bryant, Lei Guo, Mugimane G Manjanatha, Tong Zhou, Kristine L Witt, Nan Mei,

Pyrrolizidine alkaloid (PA)-containing plants are among the most common poisonous plants affecting humans, livestock, and wildlife worldwide. A large number of PAs are known to induce genetic damage after metabolic activation. In the present study, using a battery of fourteen newly developed TK6 cell lines, each expressing a single human ... Read more >>

Food Chem Toxicol (Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association)
[2020, 145:111662]

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