Full Text Journal Articles by
Author Tomoko Nagata

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Dietary soybean oil, canola oil and partially-hydrogenated soybean oil affect testicular tissue and steroid hormone levels differently in the miniature pig.

Daisuke Miyazawa, Naoki Ohara, Kazuyo Yamada, Yuko Yasui, Kazuya Kitamori, Yoshiaki Saito, Kenji Usumi, Tomoko Nagata, Tsunemasa Nonogaki, Yoko Hashimoto, Yoshimichi Miyashiro, Seijiro Homma, Harumi Okuyama,

The present study was conducted to examine the influence of dietary canola oil (CAN) and partially-hydrogenated soybean oil (HSO) compared to soybean oil (SOY, control) on the morphology and function of testes using miniature pigs as the test subject. Male miniature pigs were fed a diet containing 10%SOY, 9%CAN+1%SOY, or ... Read more >>

Food Chem. Toxicol. (Food and Chemical Toxicology)
[2020, 135:110927]

Cited: 0 times

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Abnormal Amino Acid Profiles of Blood and Cerebrospinal Fluid from Cystathionine β-Synthase-Deficient Mice, an Animal Model of Homocystinuria.

Noriyuki Akahoshi, Akira Yokoyama, Tomoko Nagata, Asumi Miura, Shotaro Kamata, Isao Ishii,

Mental retardation is the most common feature among inborn errors of amino acid metabolism. Patients with homocystinuria/homocysteinemia caused by cystathionine β-synthase (CBS) deficiency suffer from thromboembolism and mental retardation from early ages; therefore, detection by newborn screening is performed. Furthermore, elevated levels of serum homocysteine during pregnancy are associated with ... Read more >>

Biol. Pharm. Bull. (Biological & pharmaceutical bulletin)
[2019, 42(6):1054-1057]

Cited: 1 time

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Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14.

Kimiko Takebayashi-Suzuki, Hidenori Konishi, Tatsuo Miyamoto, Tomoko Nagata, Misa Uchida, Atsushi Suzuki,

During early vertebrate embryogenesis, bone morphogenetic proteins (BMPs) belonging to the transforming growth factor-β (TGF-β) family of growth factors play a central role in dorsal-ventral (DV) patterning of embryos, while other growth factors such as Wnt and fibroblast growth factor (FGF) family members regulate formation of the anterior-posterior (AP) axis. ... Read more >>

Dev. Growth Differ. (Development, growth & differentiation)
[2018, 60(3):158-173]

Cited: 1 time

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pH-Dependent structural diversity of a 2-pyridinemethanol Cu complex and its relatively strong magnetic exchange coupling via hydrogen bonding.

Tomohiko Hamaguchi, Tomoko Nagata, Shinya Hayami, Satoshi Kawata, Isao Ando,

The diversity of the self-assembled structures of a Cu complex via hydrogen bonding, including a square planar unit, is reported. The Cu complex forms two self-assembled structures by hydrogen bonding, depending on the acidity of the recrystallization conditions. A linear chain structure can be produced under acidic conditions, and a ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2017, 46(19):6196-6201]

Cited: 0 times

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Efficacy of Fibroblast Growth Factor on Epithelialization of the Neovagina in Patients with Mayer-Rokitansky-Küster-Hauser Syndrome Who Underwent Vaginoplasty.

Tomoko Nagata, Aiko Kawano, Makiko Koyama, Tomomi Nakamura, Fumiki Hirahara, Tadaaki Nakajima, Tomomi Sato, Hideya Sakakibara,

To evaluate the effect of fibroblast growth factor (FGF) on epithelialization of neovagina in patients with Mayer-Rokitansky-Küster-Hauser syndrome who underwent vaginoplasty.Observational study.University hospital.Seven patients with Mayer-Rokitansky-Küster-Hauser syndrome.Cytological examination was done on vaginal smear samples from the site of completed epithelialization, and tissue was collected from the epithelialized part for histological ... Read more >>

J Pediatr Adolesc Gynecol (Journal of pediatric and adolescent gynecology)
[2017, 30(3):400-404]

Cited: 1 time

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Efficacy of estrogen replacement therapy (ERT) on uterine growth and acquisition of bone mass in patients with Turner syndrome.

Tomomi Nakamura, Taku Tsuburai, Aya Tokinaga, Izumi Nakajima, Reiko Kitayama, Yuichi Imai, Tomoko Nagata, Hiroshi Yoshida, Fumiki Hirahara, Hideya Sakakibara,

Estrogen replacement therapy (ERT) is necessary for uterine development and bone mass acquisition in women with Turner syndrome (TS) suffering from ovarian insufficiency. However, adequate ERT regimens have not yet been established. The aim of this study was to evaluate the efficacy of ERT for both uterine development and bone ... Read more >>

Endocr. J. (Endocrine journal)
[2015, 62(11):965-970]

Cited: 8 times

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Effects of arachidonic acid intake on inflammatory reactions in dextran sodium sulphate-induced colitis in rats.

Yukiko Naito, Xu Ji, Shigehiro Tachibana, Satoko Aoki, Mami Furuya, Yoshiyuki Tazura, Daisuke Miyazawa, Akiko Harauma, Toru Moriguchi, Tomoko Nagata, Naoharu Iwai, Naoki Ohara,

The aim of this study was to investigate the effects of the administration of oral arachidonic acid (AA) in rats with or without dextran sulphate sodium (DSS)-induced inflammatory bowel disease. Male Wistar rats were administered AA at 0, 5, 35 or 240 mg/kg daily by gavage for 8 weeks. Inflammatory ... Read more >>

Br. J. Nutr. (The British journal of nutrition)
[2015, 114(5):734-745]

Cited: 3 times

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Differential adaptive responses to 1- or 2-day fasting in various mouse tissues revealed by quantitative PCR analysis.

Junya Yamamoto, Shotaro Kamata, Asumi Miura, Tomoko Nagata, Ryo Kainuma, Isao Ishii,

Dietary or caloric restriction confers various clinical benefits. Short-term fasting of mice is a common experimental procedure that may involve systemic metabolic remodeling, which may significantly affect experimental outputs. This study evaluated adaptive cellular responses after 1- or 2-day fasting in 13 mouse tissues by quantitative PCR using 15 marker ... Read more >>

FEBS Open Bio (FEBS open bio)
[2015, 5:357-368]

Cited: 5 times

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Present status of the experimental aspect of RFe₂O₄ study.

Naoshi Ikeda, Tomoko Nagata, Jun Kano, Shigeo Mori,

We give a brief review of the experimental research on a triangular mixed valence iron oxide RFe2O4 (R = Y, Dy, Ho, Er, Tm, Yb, Lu, Sc or In). Interest in this material has been increasing every year because of the fascinating but complicated interaction between spin, charge and the orbital state ... Read more >>

J Phys Condens Matter (Journal of physics. Condensed matter : an Institute of Physics journal)
[2015, 27(5):053201]

Cited: 0 times

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Intramolecular interactions that induce helical rearrangement upon rhodopsin activation: light-induced structural changes in metarhodopsin IIa probed by cysteine S-H stretching vibrations.

Yoichi Yamazaki, Tomoko Nagata, Akihisa Terakita, Hideki Kandori, Yoshinori Shichida, Yasushi Imamoto,

Rhodopsin undergoes rearrangements of its transmembrane helices after photon absorption to transfer a light signal to the G-protein transducin. To investigate the mechanism by which rhodopsin adopts the transducin-activating conformation, the local environmental changes in the transmembrane region were probed using the cysteine S-H group, whose stretching frequency is well ... Read more >>

J. Biol. Chem. (The Journal of biological chemistry)
[2014, 289(20):13792-13800]

Cited: 2 times

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Mapping of the local environmental changes in proteins by cysteine scanning.

Yoichi Yamazaki, Tomoko Nagata, Akihisa Terakita, Hideki Kandori, Yoshinori Shichida, Yasushi Imamoto,

Protein conformational changes, which regulate the activity of proteins, are induced by the alternation of intramolecular interactions. Therefore, the detection of the local environmental changes around the key amino acid residues is essential to understand the activation mechanisms of functional proteins. Here we developed the methods to scan the local ... Read more >>

Biophysics (Nagoya-shi) (Biophysics (Nagoya-shi, Japan))
[2014, 10:1-7]

Cited: 1 time

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[Home care and place of death for elderly people living in the remote islands of Japan. An examination on the presence of inpatient facilities].

Naoko Horikoshi, Yuki Kuwahara, Atsuko Taguchi, Tomoko Nagata, Sachiyo Murashima,

OBJECTIVES: The purpose of this study was to clarify the actual status of end-of-life care for elderly people living in the remote islands of Japan, and whether the presence of inpatient facilities was related to the place of death, so as to obtain suggestions for constructing a system of end-of-life ... Read more >>

Nihon Koshu Eisei Zasshi ([Nihon koshu eisei zasshi] Japanese journal of public health)
[2013, 60(7):412-421]

Cited: 0 times

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Magnetoelectric effect driven by magnetic domain modification in LuFe2O4.

Takashi Kambe, Yukimasa Fukada, Jun Kano, Tomoko Nagata, Hiroyuki Okazaki, Takayoshi Yokoya, Shuichi Wakimoto, Kazuhisa Kakurai, Naoshi Ikeda,

The magnetocapacitance effect was investigated using impedance spectroscopy on single crystals of LuFe(2)O(4). The intrinsic impedance response could be separated from the interfacial response and showed a clear hysteresis loop below T(Ferri)∼240  K under the magnetic field. The neutron diffraction experiment under the magnetic field proves the origin of the dielectric ... Read more >>

Phys. Rev. Lett. (Physical review letters)
[2013, 110(11):117602]

Cited: 0 times

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Expression of xSDF-1α, xCXCR4, and xCXCR7 during gastrulation in Xenopus laevis.

Surabhi-Kirti Mishra, Tomoko Nagata, Kazuya Furusawa, Aoki Sasaki, Akimasa Fukui,

Chemokines play a crucial role in developmental processes and recent studies have revealed that they also control gastrulation movements. In this paper, we report the expression patterns of xSDF-1α, xCXCR4 and xCXCR7 and regulation of the expression of xSDF-1α and xCXCR4 during gastrulation. We performed whole mount in situ hybridization ... Read more >>

Int. J. Dev. Biol. (The International journal of developmental biology)
[2013, 57(1):95-100]

Cited: 6 times

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The effect of ropinirole on apathy and depression after herpes encephalitis.

Naoto Kohno, Yoko Nabika, Genya Toyoda, Hirokazu Bokura, Tomoko Nagata, Shuhei Yamaguchi,

We describe a 76-year-old man with herpes encephalitis whose symptom of severe apathy was improved by the dopamine D2/D3 receptor agonist ropinirole. Brain magnetic resonance imaging had shown lesions in the patient's right mesial temporal cortex, right insula, and bilateral medial frontal regions. During treatment with acyclovir, he had developed ... Read more >>

Cogn Behav Neurol (Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology)
[2012, 25(2):98-102]

Cited: 0 times

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Delayed reproductive dysfunction in female rats induced by early life exposure to low-dose diethylstilbestrol.

Ryo Ohta, Hideo Ohmukai, Hideki Marumo, Tomoko Shindo, Tomoko Nagata, Hiroshi Ono,

A one-lifespan test was carried out to establish a test protocol for endocrine-disrupting chemicals (EDCs). Diethylstilbestrol was administered by oral gavage to neonatal rats at doses of 0.05, 0.5 and 5 μg/kg/day for 5 days after birth. Abnormal estrous cycles were observed throughout the study in all females from the ... Read more >>

Reprod. Toxicol. (Reproductive toxicology (Elmsford, N.Y.))
[2012, 34(3):323-330]

Cited: 6 times

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Tris(pyridin-2-yl-methanol)nickel(II) hexa-fluoridophosphate trifluoro-acetate.

Tomohiko Hamaguchi, Tomoko Nagata, Satoshi Kawata, Isao Ando,

In the crystal structure of the title complex, [Ni(C(6)H(7)NO)(3)](PF(6))(C(2)F(3)O(2)), the Ni(II) ion is in a slightly distorted octa-hedral NiO(3)N(3) coordination geometry with each of the three N and three O atoms in a meridional coordination. In the crystal, the complex mol-ecules and the trifluoro-acetate anions are connected via O-H⋯O hydrogen ... Read more >>

Acta Crystallogr Sect E Struct Rep Online (Acta crystallographica. Section E, Structure reports online)
[2011, 67(Pt 11):m1632]

Cited: 1 time

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Congenital omphalocele and polyhydramnios: a study of 52 cases.

Katsusuke Ozawa, Hiroshi Ishikawa, Yasuyo Maruyama, Tomoko Nagata, Hiromi Nagase, Yasufumi Itani, Kenji Kurosawa, Michiko Yamanaka,

INTRODUCTION: Unlike gastroschisis, congenital omphalocele is often associated with other anomalies and is frequently complicated by polyhydramnios. We examined the relationships between polyhydramnios, pregnancy outcome and fetal prognosis. PATIENTS AND METHODS: Clinical data from cases diagnosed antenatally with congenital omphalocele from 1993 to 2006 were analyzed retrospectively. RESULTS: Fifty-two cases ... Read more >>

Fetal. Diagn. Ther. (Fetal diagnosis and therapy)
[2011, 30(3):184-188]

Cited: 1 time

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Health management of adults with Turner syndrome: an attempt at multidisciplinary medical care by gynecologists in cooperation with specialists from other fields.

Hideya Sakakibara, Hiroshi Yoshida, Maki Takei, Yukiko Katsuhata, Makiko Koyama, Tomoko Nagata, Masahiko Ishikawa, Fumiki Hirahara,

AIM: Since women with Turner Syndrome (TS) have various complications, they require comprehensive medical evaluation and multidisciplinary treatment. Although TS patients receive adequate care in childhood, many adults with TS do not. Since most TS adults attend gynecologists for hormone replacement therapy, we suggest gynecologists take primary responsibility for their ... Read more >>

J. Obstet. Gynaecol. Res. (The journal of obstetrics and gynaecology research)
[2011, 37(7):836-842]

Cited: 12 times

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[Rapid determination of theophylline, theobromine and caffeine in dietary supplements containing guarana by ultra-performance liquid chromatography].

Takashi Hasegawa, Kazunaga Takahashi, Masaaki Saijo, Toshiyasu Ishii, Tomoko Nagata,

A rapid and simple method for determination of theophylline, theobromine and caffeine in dietary supplements containing guarana by ultra-performance liquid chromatography (UPLC) has been developed. Theophylline, theobromine and caffeine were extracted from finely powdered samples with water in a boiling water bath for 20 min, then the extracts were filtered ... Read more >>

Shokuhin Eiseigaku Zasshi (Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan)
[2009, 50(6):304-310]

Cited: 2 times

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Isolation and structural elucidation of cyclopentynafil and N-octylnortadalafil found in a dietary supplement.

Takashi Hasegawa, Kazunaga Takahashi, Masaaki Saijo, Toshiyasu Ishii, Tomoko Nagata, Masaaki Kurihara, Yuji Haishima, Yukihiro Goda, Nobuo Kawahara,

A new sildenafil analogue, cyclopentynafil (1) and a new tadalafil analogue, N-octylnortadalafil (2) were isolated from a dietary supplement illegally marketed for erectile dysfunction. The structures of the sildenafil and tadalafil analogues were elucidated by using HPLC-photodiode array (PDA), LC-MS, high-resolution MS, NMR and circular dichroism (CD). These compounds were ... Read more >>

Chem. Pharm. Bull. (Chemical & pharmaceutical bulletin)
[2009, 57(2):185-189]

Cited: 13 times

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Observation of fetal brain in a rat valproate-induced autism model: a developmental neurotoxicity study.

Makiko Kuwagata, Tetsuo Ogawa, Seiji Shioda, Tomoko Nagata,

Prenatal exposure to chemicals is well known to induce developmental abnormalities in the central nervous system of children. Developmental neurotoxicity (DNT) tests are important to identify neurotoxic agents and prevent neurodevelopmental disorders. We have investigated DNT, focusing on the fetal brain shortly after chemical exposure. To demonstrate a usefulness of ... Read more >>

Int. J. Dev. Neurosci. (International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience)
[2009, 27(4):399-405]

Cited: 37 times

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Similar changes in clinical and pathological parameters in Wistar Kyoto rats after a 13-week dietary intake of canola oil or a fatty acid composition-based interesterified canola oil mimic.

Naoki Ohara, Yukiko Naito, Kikuko Kasama, Tomoko Shindo, Hiromichi Yoshida, Tomoko Nagata, Harumi Okuyama,

Canola oil (CO) given as a dietary fat deteriorates hypertension-related condition and shortens the life of stroke-prone spontaneously hypertensive rats (SHRSP). Although substances other than fatty acids have been presumed as causatives, CO mimics consisting of oils other than CO also shorten the life. In this study we intended to ... Read more >>

Food Chem. Toxicol. (Food and Chemical Toxicology)
[2009, 47(1):157-162]

Cited: 6 times

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Dietary intake of rapeseed oil as the sole fat nutrient in Wistar rats--lack of increase in plasma lipids and renal lesions.

Naoki Ohara, Yukiko Naito, Tomoko Nagata, Shigehiro Tachibana, Mari Okimoto, Harumi Okuyama,

Dietary rapeseed (canola) oil (CO) given as the only fat nutrient shortens life in stroke-prone spontaneously hypertensive rats (SHRSP), compared with SHRSP given soybean oil (SO) instead of CO. CO ingestion increases plasma lipids and causes renal lesions in SHRSP and in spontaneously hypertensive rats (SHR), and increases plasma lipids ... Read more >>

J Toxicol Sci (The Journal of toxicological sciences)
[2008, 33(5):641-645]

Cited: 3 times

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Structural elucidation of a tadalafil analogue found in a dietary supplement.

Takashi Hasegawa, Masaaki Saijo, Toshiyasu Ishii, Tomoko Nagata, Yuji Haishima, Nobuo Kawahara, Yukihiro Goda,

A tadalafil analogue was detected in a dietary supplement marketed for tonic effect, along with hydroxyhomosildenafil and aminotadalafil. The tadalafil analogue was isolated by preparative thin layer chromatography (TLC) and its structure was elucidated using high-performance liquid chromatography (HPLC), liquid chromatography electrospray ionization-mass spectrometry (LC-ESI-MS), Fourier transform-ion cyclotron resonance-mass spectrometry ... Read more >>

Shokuhin Eiseigaku Zasshi (Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan)
[2008, 49(4):311-315]

Cited: 2 times

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