Full Text Journal Articles by
Author Todd F Duffield

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The effect of pegbovigrastim on early-lactation disease, production, and reproduction in dairy cows.

Sabrina J Van Schyndel, Jocelyn Dubuc, Osvaldo Bogado Pascottini, Jérôme Carrier, David F Kelton, Todd F Duffield, Stephen J LeBlanc,

The objective of this randomized, double-blind, controlled trial was to evaluate the effect of pegbovigrastim (pegylated recombinant bovine granulocyte colony-stimulating factor) on early-lactation disease, milk yield, and reproduction on commercial dairy farms. A total of 1,607 Holstein cows from 6 farms in Ontario and Québec, Canada, were randomly assigned to ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, :]

Cited: 0 times

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Graduate Student Literature Review: What do we know about the effects of clinical and subclinical hypocalcemia on health and performance of dairy cows?

Rita Couto Serrenho, Trevor J DeVries, Todd F Duffield, Stephen J LeBlanc,

This narrative literature review summarizes findings regarding the associations of clinical and subclinical hypocalcemia with postpartum health, reproduction, and milk production. To better understand the effects of hypocalcemia, we reviewed clinical and subclinical presentations of the condition and the dynamics of blood Ca concentration in the early postpartum period. We ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, 104(5):6304-6326]

Cited: 0 times

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Controlled trial of the effect of negative dietary cation-anion difference prepartum diets on milk production, reproductive performance, and culling of dairy cows.

Rita Couto Serrenho, Tony C Bruinjé, Emma I Morrison, Trevor J DeVries, Todd F Duffield, Stephen J LeBlanc,

Our objective was to assess the effects of feeding negative dietary cation-anion difference (DCAD) prepartum diets on milk production, reproductive performance, and culling. Cows from 4 commercial farms in Ontario, Canada were enrolled in a pen-level controlled trial from November 2017 to April 2019. Close-up pens (1 per farm) with ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, 104(6):6919-6928]

Cited: 0 times

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Randomized controlled trial assessing the effects of xylazine sedation in 2- to 6-week-old dairy calves disbudded with a cautery iron.

Cassandra N Reedman, Todd F Duffield, Trevor J DeVries, Kerry D Lissemore, Ian J Duncan, Charlotte B Winder,

The use of local anesthesia and a nonsteroidal anti-inflammatory drug (NSAID) can reduce indicators of pain and inflammation and encourage self-rewarding behavior in calves following disbudding. Although the use of sedation may be recommended as a best practice for disbudding, there is little research in this area. The objective of ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, 104(5):5881-5897]

Cited: 0 times

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Controlled trial of the effect of negative dietary cation-anion difference on postpartum health of dairy cows.

Rita Couto Serrenho, Tony C Bruinjé, Emma I Morrison, Trevor J DeVries, Todd F Duffield, Stephen J LeBlanc,

The objective of this study was to assess the effects of feeding negative dietary cation-anion difference (DCAD) dry cow diets on postpartum health. Cows from 4 commercial dairy farms in Ontario, Canada, were enrolled in a pen-level controlled trial from November 2017 to April 2019. Close-up pens (1 per farm), ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, 104(6):6929-6943]

Cited: 0 times

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Randomized control trial assessing the efficacy of pain control strategies for caustic paste disbudding in dairy calves younger than 9 days of age.

Cassandra N Reedman, Todd F Duffield, Trevor J DeVries, Kerry D Lissemore, Niel A Karrow, Ziwei Li, Charlotte B Winder,

Disbudding is a common procedure practiced in the dairy industry and is known to cause pain when performed without pain control. Dairy producers who disbud calves with caustic paste are less likely to provide pain control than those using cautery. Little research has been conducted on pain control for caustic ... Read more >>

J Dairy Sci (Journal of dairy science)
[2020, 103(8):7339-7350]

Cited: 1 time

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The effect of prepartum negative dietary cation-anion difference and serum calcium concentration on blood neutrophil function in the transition period of healthy dairy cows.

Rita Couto Serrenho, Emma I Morrison, Osvaldo Bogado Pascottini, Trevor J DeVries, Todd F Duffield, Stephen J LeBlanc,

Our objectives were to assess the effects of a diet with a negative dietary cation-anion difference (DCAD) before calving on phagocytosis (Pc) and oxidative burst (OB) function of circulating neutrophils, and to determine the associations of serum ionized (iCa) and total calcium (tCa) concentrations with Pc and OB in transition ... Read more >>

J Dairy Sci (Journal of dairy science)
[2020, 103(7):6200-6208]

Cited: 0 times

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Short communication: The effect of calcium supplementation at calving on neutrophil function.

Cynthia L Miltenburg, Todd F Duffield, Dorothee Bienzle, Elizabeth L Scholtz, Stephen J LeBlanc,

Low total blood calcium concentration after calving has been demonstrated to be a risk factor for reduced neutrophil function. The objective of this study was to evaluate whether administration of an injectable calcium supplement product soon after calving increased neutrophil oxidative burst or phagocytosis capacity. Cows (n = 27) from ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(10):9505-9509]

Cited: 0 times

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Associations between the general condition of culled dairy cows and selling price at Ontario auction markets.

Allison K G Moorman, Todd F Duffield, M Ann Godkin, David F Kelton, Jeffrey Rau, Derek B Haley,

Dairy cows are culled from the herd for a variety of reasons, the most common being fertility problems, low milk production, or udder problems. Disease and injury can contribute to the decision to cull either directly, or indirectly, by causing fertility or production problems, leading to culling. Disease or injury ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(11):10580-10588]

Cited: 2 times

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Canadian National Dairy Study: Heifer calf management.

Charlotte B Winder, Cathy A Bauman, Todd F Duffield, Herman W Barkema, Greg P Keefe, Jocelyn Dubuc, Fabienne Uehlinger, David F Kelton,

In the past decade, substantial changes have occurred in the way dairy heifer calves are managed. The objectives of this study, part of phase I of the 2015 Canadian National Dairy Study, were to examine heifer calf health and adoption of rearing practices, and to explore factors associated with different ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(11):10565-10579]

Cited: 2 times

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The effect of prepartum feeding and lying space on metabolic health and immune function.

Cynthia L Miltenburg, Todd F Duffield, Dorothee Bienzle, Elizabeth L Scholtz, Stephen J LeBlanc,

The determinants of metabolic and reproductive health disorders in the peripartum period and the degree to which feeding and lying space and management can influence health are only partially understood. The objective of this randomized controlled study was to determine whether providing noncompetitive feeding and lying access in the close-up ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(6):5294-5306]

Cited: 4 times

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Effects of local anesthetic or systemic analgesia on pain associated with cautery disbudding in calves: A systematic review and meta-analysis.

Charlotte B Winder, Cynthia L Miltenburg, Jan M Sargeant, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

Disbudding is a common management procedure performed on dairy farms and, when done without pain mitigation, is viewed as a key welfare issue. Use of pain control has increased in recent years, but full adoption of anesthesia and analgesia by veterinarians or dairy producers has not been achieved. This may ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(6):5411-5427]

Cited: 8 times

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Comparison of online, hands-on, and a combined approach for teaching cautery disbudding technique to dairy producers.

Charlotte B Winder, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

The use of pain control for disbudding and dehorning is important from both an animal and industry perspective. Best practices include the use of local anesthetic, commonly given as a cornual nerve block (CNB), and a nonsteroidal anti-inflammatory drug. The proportion is decreasing, but many dairy producers do not use ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(1):840-849]

Cited: 2 times

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Clinical trial of local anesthetic protocols for acute pain associated with caustic paste disbudding in dairy calves.

Charlotte B Winder, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

Caustic paste disbudding is becoming more commonplace in North America. A large body of work has examined pain control for cautery disbudding and surgical dehorning, but fewer studies have evaluated pain control for caustic paste disbudding, and results conflict regarding benefits of local anesthesia. In humans, the pain associated with ... Read more >>

J Dairy Sci (Journal of dairy science)
[2017, 100(8):6429-6441]

Cited: 6 times

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Comparison of an online learning module to hands-on training in teaching a cautery disbudding technique for dairy calves including cornual nerve block application.

Charlotte B Winder, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

Disbudding and dehorning are common procedures on dairy farms. In a recent survey of Ontario dairy producers, 38% reported not using local anesthetic for these procedures. Use of pain control is important for both calf welfare and industry sustainability. Use of local anesthetic requires technical training, typically provided by a ... Read more >>

Can Vet J (The Canadian veterinary journal = La revue veterinaire canadienne)
[2017, 58(7):735-740]

Cited: 3 times

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Investigating the within-herd prevalence and risk factors for ketosis in dairy cattle in Ontario as diagnosed by the test-day concentration of β-hydroxybutyrate in milk.

Elise H Tatone, Todd F Duffield, Stephen J LeBlanc, Trevor J DeVries, Jessica L Gordon,

An observational study of 790 to over 3,000 herds was conducted to estimate the within-herd prevalence and cow-level risk factors for ketosis in dairy cattle in herds that participate in a Dairy Herd Improvement Association (DHIA) program. Ketosis or hyperketolactia (KET) was diagnosed as milk β-hydroxybutyrate ≥0.15 mmol/L at first ... Read more >>

J Dairy Sci (Journal of dairy science)
[2017, 100(2):1308-1318]

Cited: 10 times

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Practices for the disbudding and dehorning of dairy calves by veterinarians and dairy producers in Ontario, Canada.

Charlotte B Winder, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

Disbudding and dehorning dairy calves is very common, despite the introduction of polled genetics to most dairy breeds. Appropriate pain-control practices for these procedures affect both calf welfare and public perception of the dairy industry. Previously published work has shown that North American dairy producers have not widely adopted use ... Read more >>

J Dairy Sci (Journal of dairy science)
[2016, 99(12):10161-10173]

Cited: 16 times

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Mortality risk factors for calves entering a multi-location white veal farm in Ontario, Canada.

Charlotte B Winder, David F Kelton, Todd F Duffield,

Mortality in preweaned dairy-breed calves, whether they are replacement dairy heifers, veal animals, or dairy beef animals, represents both a welfare issue and a source of economic loss for the industries involved. Studies describing morbidity and mortality in veal calves have illustrated different management practices and requirements in terms of ... Read more >>

J Dairy Sci (Journal of dairy science)
[2016, 99(12):10174-10181]

Cited: 14 times

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Economic value of ionophores and propylene glycol to prevent disease and treat ketosis in Canada.

Khaled Gohary, Michael W Overton, Michael Von Massow, Stephen J LeBlanc, Kerry D Lissemore, Todd F Duffield,

A partial budget model was developed to evaluate the economic value of Rumensin Controlled Release Capsule (CRC) boluses when administered before calving to reduce disease and increase milk production. After accounting for disease incidences in a herd and the percentage by which Rumensin CRC can reduce them, and the increase ... Read more >>

Can Vet J (The Canadian veterinary journal = La revue veterinaire canadienne)
[2016, 57(7):733-740]

Cited: 2 times

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The cost of a case of subclinical ketosis in Canadian dairy herds.

Khaled Gohary, Michael W Overton, Michael Von Massow, Stephen J LeBlanc, Kerry D Lissemore, Todd F Duffield,

The objective of this study was to develop a model to estimate the cost of a case of subclinical ketosis (SCK) in Canadian dairy herds. Costs were derived from the default inputs, and included increased clinical disease incidence attributable to SCK, $76; longer time to pregnancy, $57; culling and death ... Read more >>

Can Vet J (The Canadian veterinary journal = La revue veterinaire canadienne)
[2016, 57(7):728-732]

Cited: 4 times

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A randomized controlled trial of dexamethasone as an adjunctive therapy to propylene glycol for treatment of hyperketonemia in postpartum dairy cattle.

Elise H Tatone, Todd F Duffield, Michael B Capel, Trevor J DeVries, Stephen J LeBlanc, Jessica L Gordon,

Treatment of hyperketonemia with oral propylene glycol has proven efficacy but the cure rate remains moderate. Dexamethasone has long been suggested as a treatment for hyperketonemia, even though evidence of its efficacy is contradictory. The objective of this randomized controlled trial was to evaluate the effect of adding a single ... Read more >>

J Dairy Sci (Journal of dairy science)
[2016, 99(11):8991-9000]

Cited: 5 times

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Randomized clinical trial of a calcium supplement for improvement of health in dairy cows in early lactation.

Cynthia L Miltenburg, Todd F Duffield, Dorothee Bienzle, Elizabeth L Scholtz, Stephen J LeBlanc,

Prophylactic Ca supplementation immediately after calving is a common strategy to prevent clinical and subclinical hypocalcemia in parturient dairy cows. The objective of this study was to evaluate the effect of prophylactic administration of an injected Ca supplement on blood Ca concentration at 24 and 48h after treatment, incidence risk ... Read more >>

J Dairy Sci (Journal of dairy science)
[2016, 99(8):6550-6562]

Cited: 8 times

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A systematic review and meta-analysis of the diagnostic accuracy of point-of-care tests for the detection of hyperketonemia in dairy cows.

Elise H Tatone, Jessica L Gordon, Jessie Hubbs, Stephen J LeBlanc, Trevor J DeVries, Todd F Duffield,

Several rapid tests for use on farm have been validated for the detection of hyperketonemia (HK) in dairy cattle, however the reported sensitivity and specificity of each method varies and no single study has compared them all. Meta-analysis of diagnostic test accuracy is becoming more common in human medical literature ... Read more >>

Prev Vet Med (Preventive veterinary medicine)
[2016, 130:18-32]

Cited: 6 times

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Two-Stage Rumen Cannulation Technique in Dairy Cows.

Roger Martineau, Julien G Proulx, Cristiano Côrtes, Andre F Brito, Todd F Duffield,

<h4>Objective</h4>To describe a 2-stage rumen cannulation technique for dairy cows.<h4>Study design</h4>Case series.<h4>Animals</h4>172 dairy cows from 2 research institutions.<h4>Methods</h4>The 2-stage rumen cannulation technique first exteriorized a rumen segment within a wooden clamp, fixing the clamp to the skin with 6 mattress sutures. After 1 week, the necrotic rumen segment was removed, ... Read more >>

Vet Surg (Veterinary surgery : VS)
[2015, 44(5):551-556]

Cited: 2 times

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Factors associated with survival in the herd for dairy cows following surgery to correct left displaced abomasum.

Jennifer L Reynen, David F Kelton, Stephen J LeBlanc, Nathalie C Newby, Todd F Duffield,

Left displaced abomasum (LDA) is a common problem in dairy cows. There have been numerous studies focused on predicting prognosis for right displaced abomasal corrective surgery, but a paucity of studies exist focused on more common LDA surgeries. Our objective was to determine if survival to 60 d or 1 ... Read more >>

J Dairy Sci (Journal of dairy science)
[2015, 98(6):3806-3813]

Cited: 3 times

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