Full Text Journal Articles by
Author Tiziana Coliva

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Acute myeloid leukaemia niche regulates response to L-asparaginase.

Ilaria M Michelozzi, Valentina Granata, Giada De Ponti, Gaia Alberti, Chiara Tomasoni, Laura Antolini, Carlo Gambacorti-Passerini, Bernhard Gentner, Francesco Dazzi, Andrea Biondi, Tiziana Coliva, Carmelo Rizzari, Alice Pievani, Marta Serafini,

Eradicating the malignant stem cell is the ultimate challenge in the treatment of leukaemia. Leukaemic stem cells (LSC) hijack the normal haemopoietic niche, where they are mainly protected from cytotoxic drugs. The anti-leukaemic effect of L-asparaginase (ASNase) has been extensively investigated in acute lymphoblastic leukaemia, but only partially in acute ... Read more >>

Br. J. Haematol. (British journal of haematology)
[2019, 186(3):420-430]

Cited: 2 times

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Constitutional and somatic deletions of the Williams-Beuren syndrome critical region in non-Hodgkin lymphoma.

David Guenat, Samuel Quentin, Carmelo Rizzari, Catarina Lundin, Tiziana Coliva, Patrick Edery, Helen Fryssira, Laurent Bermont, Christophe Ferrand, Jean Soulier, Christophe Borg, Pierre-Simon Rohrlich,

Here, we report and investigate the genomic alterations of two novel cases of Non-Hodgkin Lymphoma (NHL) in children with Williams-Beuren syndrome (WBS), a multisystem disorder caused by 7q11.23 hemizygous deletion. Additionally, we report the case of a child with NHL and a somatic 7q11.23 deletion. Although the WBS critical region ... Read more >>

J Hematol Oncol (Journal of hematology & oncology)
[2014, 7:82]

Cited: 4 times

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Congenital and acquired neutropenias consensus guidelines on therapy and follow-up in childhood from the Neutropenia Committee of the Marrow Failure Syndrome Group of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica).

Francesca Fioredda, Michaela Calvillo, Sonia Bonanomi, Tiziana Coliva, Fabio Tucci, Piero Farruggia, Marta Pillon, Baldassarre Martire, Roberta Ghilardi, Ugo Ramenghi, Daniela Renga, Giuseppe Menna, Anna Pusiol, Angelica Barone, Eleonora Gambineri, Giovanni Palazzi, Gabriella Casazza, Marina Lanciotti, Carlo Dufour, ,

The management of congenital and acquired neutropenias presents some differences according to the type of the disease. Treatment with recombinant human granulocyte-colony stimulating factor (G-CSF) is not standardized and scanty data are available on the best schedule to apply. The frequency and the type of longitudinal controls in patients affected ... Read more >>

Am. J. Hematol. (American journal of hematology)
[2012, 87(2):238-243]

Cited: 13 times

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Predictive factors of relapse and survival in childhood acute myeloid leukemia: role of minimal residual disease.

Carmelo Rizzari, Giovanni Cazzaniga, Tiziana Coliva, Chiara De Angelis, Valentino Conter,

Minimal residual disease (MRD) in acute myeloid leukemia (AML) can be measured either by flow cytometry to detect leukemic immunophenotypes or by PCR amplification of fusion transcripts, gene mutations and overexpressed genes. Flow cytometry MRD is widely applicable but has an intermediate sensitivity; PCR MRD is highly sensitive but has ... Read more >>

Expert Rev Anticancer Ther (Expert review of anticancer therapy)
[2011, 11(9):1391-1401]

Cited: 6 times

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Congenital and acquired neutropenia consensus guidelines on diagnosis from the Neutropenia Committee of the Marrow Failure Syndrome Group of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica).

Francesca Fioredda, Michaela Calvillo, Sonia Bonanomi, Tiziana Coliva, Fabio Tucci, Piero Farruggia, Marta Pillon, Baldassarre Martire, Roberta Ghilardi, Ugo Ramenghi, Daniela Renga, Giuseppe Menna, Angelica Barone, Marina Lanciotti, Carlo Dufour,

Congenital and acquired neutropenia are rare disorders whose frequency in pediatric age may be underestimated due to remarkable differences in definition or misdiagnosed because of the lack of common practice guidelines. Neutropenia Committee of the Marrow Failure Syndrome Group (MFSG) of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica) elaborated this document ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2011, 57(1):10-17]

Cited: 17 times

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Novel HAX1 gene mutations associated to neurodevelopment abnormalities in two Italian patients with severe congenital neutropenia.

Marina Lanciotti, Stefania Indaco, Sonia Bonanomi, Tiziana Coliva, Elena Mastrodicasa, Gianluca Caridi, Michaela Calvillo, Carlo Dufour,

Haematologica (Haematologica)
[2010, 95(1):168-169]

Cited: 8 times

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Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia.

Paola Trombini, Tiziana Coliva, Elizabeta Nemeth, Raffaella Mariani, Tomas Ganz, Andrea Biondi, Alberto Piperno,

Hepcidin is the key regulator of systemic iron homeostasis. We describe the modulation of hepcidin production induced by plasma transfusions in a patient with congenital hypotransferrinemia that offers a unique model in which to study the mechanism of hepcidin regulation by iron and erythropoiesis. Urinary hepcidin increased from zero at ... Read more >>

Haematologica (Haematologica)
[2007, 92(10):1407-1410]

Cited: 23 times

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WT1 gene expression: useful marker for minimal residual disease in childhood myelodysplastic syndromes and juvenile myelo-monocytic leukemia?

Peter Bader, Charlotte Niemeyer, Gerrit Weber, Tiziana Coliva, Vincenzo Rossi, Hermann Kreyenberg, Anja Gerecke, Andrea Biondi,

The WT1 gene is considered to be highly expressed in patients with acute myeloid leukemia (AML), acute lymphoblastic leukemia and chronic myeloid leukemia and is thought to play a key role in maintaining the viability of leukemia cells. However, little is known about the WT1 gene expression levels in pediatric ... Read more >>

Eur. J. Haematol. (European journal of haematology)
[2004, 73(1):25-28]

Cited: 17 times

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