Full Text Journal Articles by
Author Ting Yuan

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Moxibustion for treating knee osteoarthritis: A protocol for systematic review and meta analysis.

Xue Wang, Yunfeng Jiang, Jun Xiong, Ting Yuan, Jun Yang, Xiaohong Zhou, Kai Liao, Lingling Xu,

BACKGROUND:Knee osteoarthritis (KOA) is a significant health issue because it causes pain and functional limitation. Many studies have reported that moxibustion, a treatment in traditional Chinese medicine, is effective in treating KOA. The aim of this overview is to synthesize and assess the reliability of evidence generated from these systematic ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(19):e19974]

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Synergetic performance of isothermal amplification techniques and lateral flow approach for nucleic acid diagnostics.

Omar Mukama, Chengrong Nie, Jean de Dieu Habimana, Xiaogao Meng, Yuan Ting, Fanuel Songwe, Ammar Al Farga, Samson Mugisha, Peter Rwibasira, Yinghui Zhang, Lingwen Zeng,

The advancement in developing sensitive, rapid, and specific sensing tools is crucial in diagnostics and biotechnological applications. Although various isothermal amplification approaches exist for the detection and identification of nucleic acids, post-amplicon analysis is still based on traditional methods such as gel electrophoresis, colorimetry, turbidity, which could be non-specific and ... Read more >>

Anal. Biochem. (Analytical biochemistry)
[2020, 600:113762]

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Calcitriol tablets with hybrid lipid-based solid dispersions with enhanced stability and content uniformity.

Xiao Yue, Yingtong Cui, Ting Yuan, Zhengwei Huang, Ying Huang, Xuejuan Zhang, Chen Wang, Guanlin Wang, Ruifeng Liang, Chunxia Liu, Xin Pan, Chuanbin Wu,

Calcitriol, as the biologically active form of vitamin D3, is essential for patients with renal osteopathy. The solubilization, stabilization, and content uniformity are key issues in its formulation development. In our previous study, the incomplete release of calcitriol was solved by using the hybrid lipid-based solid dispersion (SD) for calcitriol. ... Read more >>

Pharm Dev Technol (Pharmaceutical development and technology)
[2020, :1-9]

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Effectiveness and Safety of Acupuncture and Moxibustion for Primary Dysmenorrhea: An Overview of Systematic Reviews and Meta-Analyses.

Jun Yang, Jun Xiong, Ting Yuan, Xue Wang, Yunfeng Jiang, Xiaohong Zhou, Kai Liao, Lingling Xu,

Background:Acupuncture and moxibustion have been accepted as treatment options for primary dysmenorrhea (PD). So far, several systematic reviews (SRs) and meta-analyses (MAs) have reported on the efficacy and safety of acupuncture and moxibustion in treating PD. Objectives:The aim of this study was to critically summarize the evidence from relevant SRs ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2020, 2020:8306165]

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Intestinal methicillin-resistant Staphylococcus aureus causes prosthetic infection via 'Trojan Horse' mechanism: Evidence from a rat model.

Hongyi Zhu, Hanqiang Jin, Changqing Zhang, Ting Yuan,

Aims:Methicillin-resistant Staphylococcus aureus (MRSA) can cause wound infections via a 'Trojan Horse' mechanism, in which neutrophils engulf intestinal MRSA and travel to the wound, releasing MRSA after apoptosis. The possible role of intestinal MRSA in prosthetic joint infection (PJI) is unknown. Methods:Rats underwent intestinal colonization with green fluorescent protein (GFP)-tagged ... Read more >>

Bone Joint Res (Bone & joint research)
[2020, 9(4):152-161]

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Case Report of Anti-CD123 Chimeric Antigen Receptor T-Cell Therapy Followed by Radiotherapy for a Recurrence of Blastic Plasmacytoid Dendritic Cell Neoplasm After Allogeneic Hematopoietic Stem Cell Transplantation.

Yi-Li Jiang, Qing Li, Ting Yuan, Yan-Yu Jiang, Qi Deng,

Background:Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic malignancy. There is no standard chemotherapy regimen for BPDCN, and even allogeneic hematopoietic stem cell transplantation (allo-HSCT) has not been able to extend the survival of patients with BPDCN. Case Report:Here, we present a case of recurrence of BPDCN in ... Read more >>

Onco Targets Ther (OncoTargets and therapy)
[2020, 13:3425-3430]

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Single-cell RNA-seq reveals identity and heterogeneity of malignant osteoblast cells and TME in osteosarcoma

Yan Zhou, Dong Yang, Qing-Cheng Yang, Xiao-Bin Lv, Wen-Tao Huang, Zhenhua Zhou, Ya-Ling Wang, Zhichang Zhang, Ting Yuan, Xiaomin Ding, Li-Na Tang, Jian-Jun Zhang, Jun-Yi Yin, Yu-Jing Huang, Wen-Xi Yu, Yong-Gang Wang, Chen-Liang Zhou, Yang Su, Ai-Na He, Yuan-Jue Sun, Zan Shen, Bin-Zhi Qian, Peizhan Chen, Xinghua Pan, Yang Yao, Hai-Yan Hu,

ABSTRACT Osteosarcoma (OS) has high heterogeneity and poor prognosis. In order to explore the molecular mechanism of OS and the tumor micro-environment (TME) on OS, we employed single-cell RNA-sequencing (scRNA-seq) on 110,745 individual cells from OS primary lesion, recurrent focal and metastatic tissues. We identified 5 main malignant subpopulations of ... Read more >>

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Observation and analysis of 26 cases of asymptomatic SARS-COV2 infection.

Juan Zhou, Yingzheng Tan, Dan Li, Xiaojin He, Ting Yuan, Yunzhu Long,

J. Infect. (The Journal of Infection)
[2020, :]

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Targeted tumour theranostics in mice via carbon quantum dots structurally mimicking large amino acids.

Shuhua Li, Wen Su, Hao Wu, Ting Yuan, Chang Yuan, Jun Liu, Gang Deng, Xingchun Gao, Zeming Chen, Youmei Bao, Fanglong Yuan, Shixin Zhou, Hongwei Tan, Yunchao Li, Xiaohong Li, Louzhen Fan, Jia Zhu, Ann T Chen, Fuyao Liu, Yu Zhou, Miao Li, Xingchen Zhai, Jiangbing Zhou,

Strategies for selectively imaging and delivering drugs to tumours typically leverage differentially upregulated surface molecules on cancer cells. Here, we show that intravenously injected carbon quantum dots, functionalized with multiple paired α-carboxyl and amino groups that bind to the large neutral amino acid transporter 1 (which is expressed in most ... Read more >>

Nat Biomed Eng (Nature biomedical engineering)
[2020, :]

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Novel vanillin derivatives containing a 1,3,4-thiadiazole moiety as potential antibacterial agents.

Qiong Wu, Hui Cai, Ting Yuan, Shaoyuan Li, Xiuhai Gan, Baoan Song,

In this study, thirty-four novel vanillin derivatives containing a 1,3,4-thiadiazole structure were obtained and their antibacterial activities were evaluated. The results indicate that most of the title compounds displayed inhibitory effects on Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas oryzae pv. oryzicola (Xoc). Among them, compound 29 exhibited excellent antibacterial ... Read more >>

Bioorg. Med. Chem. Lett. (Bioorganic & medicinal chemistry letters)
[2020, 30(10):127113]

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Cover Image, Volume 53, Issue 2.

Lei Zhang, Yi Wang, Guorao Wu, Lizong Rao, Yanqiu Wei, Huihui Yue, Ting Yuan, Ping Yang, Fei Xiong, Shu Zhang, Qing Zhou, Zhishui Chen, Jinxiu Li, Bi‐Wen Mo, Huilan Zhang, Weining Xiong, Cong‐Yi Wang,

The cover image is based on the Original Article Blockade of JAK2 protects mice against hypoxia‐induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation by Lei Zhang et al., https://doi.org/10.1111/cpr.12742. ... Read more >>

Cell Prolif. (Cell proliferation)
[2020, 53(2):]

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Recent advances in white light-emitting diodes of carbon quantum dots.

Ping He, Yuxin Shi, Ting Meng, Ting Yuan, Yunchao Li, Xiaohong Li, Yang Zhang, Louzhen Fan, Shihe Yang,

Carbon quantum dots (CQDs) have shown great potential in optoelectronic applications. Very recently, CQDs have attracted much attention in white-emitting diodes (WLEDs) for lighting due to their characteristic broad emission, tunable fluorescence emission and high thermal stability. This mini review updates the latest research in the design of high-performance WLEDs ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(8):4826-4832]

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DKK1 is epigenetically downregulated by promoter methylation and inhibits bile acid-induced gastric intestinal metaplasia.

Wenquan Lu, Zhen Ni, Mingfu Tong, Shuqin Jiang, Jian Zhang, Chenchen Feng, Chuan Han, Ting Yuan, Na Wang, Jing Zhao, Nina Sun, Caifang Liu, Qiaoyu Jia, Qiong Wu, Hanbing Ning, Yongquan Shi,

Dickkopf-related protein 1 (DKK1) is essential to gastric cancer as an inhibitor of Wnt signaling. Gastric intestinal metaplasia (GIM) is an important precancerous lesion of gastric cancer that can be activated by bile acid reflux and chronic inflammation. However, the exact mechanism of DKK1 in bile acid-induced GIM has not ... Read more >>

Biochem. Biophys. Res. Commun. (Biochemical and biophysical research communications)
[2020, 523(3):780-786]

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Blockade of JAK2 protects mice against hypoxia-induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation.

Lei Zhang, Yi Wang, Guorao Wu, Lizong Rao, Yanqiu Wei, Huihui Yue, Ting Yuan, Ping Yang, Fei Xiong, Shu Zhang, Qing Zhou, Zhishui Chen, Jinxiu Li, Bi-Wen Mo, Huilan Zhang, Weining Xiong, Cong-Yi Wang,

OBJECTIVES:Hypoxia is an important risk factor for pulmonary arterial remodelling in pulmonary arterial hypertension (PAH), and the Janus kinase 2 (JAK2) is believed to be involved in this process. In the present report, we aimed to investigate the role of JAK2 in vascular smooth muscle cells during the course of ... Read more >>

Cell Prolif. (Cell proliferation)
[2020, 53(2):e12742]

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Heat-sensitive moxibustion for anaphylactic rhinitis: A protocol of systematic review and meta-analysis of randomized clinical trials.

Jun Xiong, Jun Yang, Ting Yuan, Xue Wang, Yunfeng Jiang, Xiaohong Zhou, Kai Liao, Lingling Xu,

BACKGROUND:Anaphylactic rhinitis (AR) is one of the most common allergic disorders globally. Heat-sensitive moxibustion (HSM) is an effective method for AR without the occurrence of drug damage. This study aims to systematically investigate the effectiveness and safety of HSM for patients with AR. METHODS:Seven relevant electronic databases from inception until ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(4):e18557]

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Anti-oral Squamous Cell Carcinoma Effects of a Potent TAZ Inhibitor AR-42.

Lingyu Su, Si Wang, Ting Yuan, Xudong Xie, Xiaoming Fu, Ping Ji, Lei Zhong, Wenzhao Liu,

Oral squamous cell carcinoma (OSCC) is one of the most common malignancies worldwide. Although great progress has been made in diagnosis and treatment strategies in recent years, the 5-year survival rate of OSCC patients is still disappointingly low. Hence, there is still an unmet medical need for sufferers with OSCC. ... Read more >>

J Cancer (Journal of Cancer)
[2020, 11(2):364-373]

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Role of Diffusional Kurtosis Imaging in Differentiating Neuromyelitis Optica-Related and Multiple Sclerosis-Related Acute Optic Neuritis: Comparison With Diffusion-Weighted Imaging.

Ping Lu, Ting Yuan, Xilan Liu, Guohong Tian, Jibin Zhang, Yan Sha,

PURPOSE:The discrimination between neuromyelitis optica (NMO)- and multiple sclerosis (MS)-related acute optic neuritis (ON) after the first presentation is difficult in clinical practice. Through a comparison with diffusion-weighted imaging using readout-segmented echo-planar imaging (RESOLVE-DWI), our aim was to determine the feasibility of diffusional kurtosis imaging (DKI) for differential diagnosis. MATERIALS ... Read more >>

J Comput Assist Tomogr (Journal of computer assisted tomography)
[2020, 44(1):47-52]

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Moxibustion for the treatment of primary dysmenorrhea: Protocol for an overview of systematic reviews.

Xue Wang, Jun Xiong, Jun Yang, Ting Yuan, Hao Fan, Yunfeng Jiang, Xiaohong Zhou, Kai Liao, Lingling Xu,

BACKGROUND:Primary dysmenorrhea (PD) is a common gynecological disease, it refers to spasmodic pain in the lower abdomen before, after or during menstruation, accompanied by general discomfort, In severe cases, fainting may occur due to severe pain, reducing the quality of patients' life and imposing a heavy burden on social medical ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(4):e18908]

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Dissection of heterocellular cross-talk in vascularized cardiac tissue mimetics.

Julian Uwe Gabriel Wagner, Minh Duc Pham, Luka Nicin, Marie Hammer, Katharina Bottermann, Ting Yuan, Rahul Sharma, David John, Marion Muhly-Reinholz, Lukas Tombor, Martin Hardt, Josef Madl, Stefanie Dimmeler, Jaya Krishnan,

Cellular specialization and interaction with other cell types in cardiac tissue is essential for the coordinated function of cell populations in the heart. The complex interplay between cardiomyocytes, endothelial cells and fibroblasts is necessary for adaptation but can also lead to pathophysiological remodeling. To understand this complex interplay, we developed ... Read more >>

J. Mol. Cell. Cardiol. (Journal of molecular and cellular cardiology)
[2020, 138:269-282]

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AR-42: A Pan-HDAC Inhibitor with Antitumor and Antiangiogenic Activities in Esophageal Squamous Cell Carcinoma.

Yuxuan Zhu, Ting Yuan, Yuan Zhang, Jianyou Shi, Lan Bai, Xingmei Duan, Rongsheng Tong, Lei Zhong,

Purpose:Esophageal squamous cell carcinoma (ESCC) is a refractory malignancy with high morbidity and mortality. Thus, there is an urgent need to find effective targets and agents for ESCC treatment. The purpose of this study was to assess the anti-ESCC effects of a pan-histone deacetylase (HDAC) inhibitor AR-42 and its mechanisms ... Read more >>

Drug Des Devel Ther (Drug design, development and therapy)
[2019, 13:4321-4330]

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miR‑195 promotes LPS‑mediated intestinal epithelial cell apoptosis via targeting SIRT1/eIF2a.

Ting Yuan, Li Zhang, Shuo Yao, Shuang-Ya Deng, Ji-Qiang Liu,

A microarray analysis of an animal model with experimental sepsis induced by caecal ligation and puncture revealed that the level of microRNA‑195 (miR‑195) was upregulated. However, to the best of our knowledge, the role of miR‑195 in sepsis remains unknown. The present study investigated the effect of miR‑195 on apoptosis ... Read more >>

Int. J. Mol. Med. (International journal of molecular medicine)
[2020, 45(2):510-518]

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The Effectiveness and Safety of Moxibustion for Treating Knee Osteoarthritis: A PRISMA Compliant Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Ting Yuan, Jun Xiong, Xue Wang, Jun Yang, Yunfeng Jiang, Xiaohong Zhou, Kai Liao, Lingling Xu,

Background:Knee osteoarthritis (KOA) seriously affects people's life. Therefore, it has already become a worldwide health concern. Moxibustion has a significant clinical effect on KOA. This systematic review and meta-analysis is performed to renew previous studies and strictly evaluate the quality of RCT and thus test the effect and safety of ... Read more >>

Pain Res Manag (Pain research & management)
[2019, 2019:2653792]

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Comparison of outcomes of haploidentical donor hematopoietic stem cell transplantation supported by third-party cord blood with HLA-matched unrelated donor transplantation.

Hairong Lyu, Wenyi Lu, Jianfeng Yao, Xia Xiao, Qing Li, Jia Wang, Juan Mu, Yao Qi, Haibo Zhu, Yili Jiang, Xin Li, Juanxia Meng, Ting Yuan, Xiaoyuan He, Erlie Jiang, Mingzhe Han, Mingfeng Zhao,

Previous study indicated that co-infusion of cord blood cells may potentially improve the outcome of haploidentical donor (HID) transplantation. In this study, we analyzed the outcomes of patients who underwent HID transplantation supported by cord blood when compared with HLA-matched unrelated donor (URD) transplantation. Starting in 2015, 40 patients with ... Read more >>

Leuk. Lymphoma (Leukemia & lymphoma)
[2020, 61(4):840-847]

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Macrophage-associated pro-inflammatory state in human islets from obese individuals.

Wei He, Ting Yuan, Kathrin Maedler,

Obesity is associated with inflammatory macrophages in insulin responsive tissues and the resulting inflammatory response is a major contributor to insulin resistance. In insulin-producing pancreatic islets, the intra-islet accumulation of macrophages is observed in patients of type 2 diabetes (T2D), but such has not been investigated in obese individuals. Here, ... Read more >>

Nutr Diabetes (Nutrition & diabetes)
[2019, 9(1):36]

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