Full Text Journal Articles by
Author Ting Tung A Chang

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Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.

Penny L Berger, Sander B Frank, Veronique V Schulz, Eric A Nollet, Mathew J Edick, Brittany Holly, Ting-Tung A Chang, Galen Hostetter, Suwon Kim, Cindy K Miranti,

The mechanisms by which Myc overexpression or Pten loss promotes prostate cancer development are poorly understood. We identified the chromatin remodeling protein, ING4, as a crucial switch downstream of Myc and Pten that is required for human prostate epithelial differentiation. Myc-induced transient expression of ING4 is required for the differentiation ... Read more >>

Cancer Res. (Cancer research)
[2014, 74(12):3357-3368]

Cited: 17 times

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Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow.

Keya De Mukhopadhyay, Abhik Bandyopadhyay, Ting-Tung A Chang, Abdel G Elkahloun, John E Cornell, Junhua Yang, Beth A Goins, I-Tien Yeh, Lu-Zhe Sun,

The origin and the contribution of breast tumor heterogeneity to its progression are not clear. We investigated the effect of a growing orthotopic tumor formed by an aggressive estrogen receptor (ER)-negative breast cancer cell line on the metastatic potential of a less aggressive ER-positive breast cancer cell line for the ... Read more >>

PLoS ONE (PloS one)
[2011, 6(6):e20473]

Cited: 6 times

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