Full Text Journal Articles by
Author Timothy F Jones

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Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery: prospective multicentre observational cohort study.

Gareth L Ackland, Tom E F Abbott, Timothy F Jones, Martin Leuwer, Rupert M Pearse, , , , ,

BACKGROUND:Elevated high-sensitivity troponin (hsTnT) after noncardiac surgery is associated with higher mortality, but the temporal relationship between early elevated troponin and the later development of noncardiac morbidity remains unclear. METHODS:Prospective observational study of patients aged ≥45 yr undergoing major noncardiac surgery at four UK hospitals (two masked to hsTnT). The ... Read more >>

Br J Anaesth (British journal of anaesthesia)
[2020, 124(5):535-543]

Cited: 0 times

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Surveillance, Epidemiology, and Estimated Burden of Neonatal Abstinence Syndrome, Tennessee, 2013-2016.

Julia Brennan, Caleb Wiedeman, John R Dunn, William Schaffner, Timothy F Jones,

OBJECTIVES:Between 2003 and 2013, the rate of neonatal abstinence syndrome (NAS)-a postnatal drug withdrawal syndrome-in Tennessee increased approximately 10-fold. NAS surveillance is relatively new, and underestimation associated with surveillance has not been described. We compared data from the Tennessee NAS public health surveillance system (TNSS) with a second source of ... Read more >>

Public Health Rep (Public health reports (Washington, D.C. : 1974))
[2019, 134(5):537-541]

Cited: 0 times

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The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients.

Lewis S Gall, Paul Vulliamy, Scarlett Gillespie, Timothy F Jones, Rochelle S J Pierre, Sabine E Breukers, Christine Gaarder, Nicole P Juffermans, Marc Maegele, Jakob Stensballe, Pär I Johansson, Ross A Davenport, Karim Brohi, ,

OBJECTIVE:To determine the characteristics of trauma patients with low levels of fibrinolysis as detected by viscoelastic hemostatic assay (VHA) and explore the underlying mechanisms of this subtype. BACKGROUND:Hyperfibrinolysis is a central component of acute traumatic coagulopathy but a group of patients present with low levels of VHA-detected fibrinolysis. There is ... Read more >>

Ann. Surg. (Annals of surgery)
[2019, 269(6):1184-1191]

Cited: 1 time

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Notes from the Field: Acute Hepatitis A Virus Infection Among Previously Vaccinated Persons with HIV Infection - Tennessee, 2018.

Julia Brennan, Kelly Moore, Lindsey Sizemore, Samantha A Mathieson, Carolyn Wester, John R Dunn, William Schaffner, Timothy F Jones,

MMWR Morb. Mortal. Wkly. Rep. (MMWR. Morbidity and mortality weekly report)
[2019, 68(14):328-329]

Cited: 0 times

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Global variation in anastomosis and end colostomy formation following left-sided colorectal resection.

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Background:End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods:This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies ... Read more >>

BJS Open (BJS open)
[2019, 3(3):403-414]

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Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy.

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BACKGROUND:The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality ... Read more >>

Br J Surg (The British journal of surgery)
[2019, 106(2):e103-e112]

Cited: 5 times

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Notes from the Field: Multiple Modes of Transmission During a Thanksgiving Day Norovirus Outbreak - Tennessee, 2017.

Julia Brennan, Steffany J Cavallo, Katie Garman, Kailey Lewis, D J Irving, Christina Moore, Linda Thomas, Jeffrey Hill, Raquel Villegas, Joe F Norman, John R Dunn, William Schaffner, Timothy F Jones,

MMWR Morb. Mortal. Wkly. Rep. (MMWR. Morbidity and mortality weekly report)
[2018, 67(46):1300-1301]

Cited: 0 times

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Educational Disabilities Among Children Born With Neonatal Abstinence Syndrome.

Mary-Margaret A Fill, Angela M Miller, Rachel H Wilkinson, Michael D Warren, John R Dunn, William Schaffner, Timothy F Jones,

BACKGROUND:Neonatal abstinence syndrome (NAS) is a postnatal drug withdrawal syndrome that can occur after intrauterine opioid exposure. Adverse neurobehavioral outcomes have been documented in infants with NAS; however, educational outcomes have not been thoroughly examined. We analyzed Tennessee data to understand the need for special educational services among infants who ... Read more >>

Pediatrics (Pediatrics)
[2018, 142(3):]

Cited: 5 times

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MicroRNAs in Acute Kidney Injury.

Timothy F Jones, Soliana Bekele, Michael J O'Dwyer, John R Prowle,

BACKGROUND:It is increasingly recognised that improved diagnosis, prognosis and treatment of acute kidney injury (AKI) requires an understanding of distinct underling cellular and molecular mechanisms (endotypes) that may distinguish overtly similar clinical AKI presentations. One important avenue of research is the post-transcriptional regulation of gene expression in response to kidney ... Read more >>

Nephron (Nephron)
[2018, 140(2):124-128]

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Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.

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BACKGROUND:Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) ... Read more >>

Surg Endosc (Surgical endoscopy)
[2018, 32(8):3450-3466]

Cited: 5 times

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Genetic Susceptibility to Postdiarrheal Hemolytic-Uremic Syndrome After Shiga Toxin-Producing Escherichia coli Infection: A Centers for Disease Control and Prevention FoodNet Study.

Asha R Kallianpur, Yuki Bradford, Rajal K Mody, Katie N Garman, Nicole Comstock, Sarah L Lathrop, Carol Lyons, Amy Saupe, Katie Wymore, Jeffrey A Canter, Lana M Olson, Amanda Palmer, Timothy F Jones,

Background:Postdiarrheal hemolytic-uremic syndrome (D+HUS) following Shiga toxin-producing Escherichia coli (STEC) infection is a serious condition lacking specific treatment. Host immune dysregulation and genetic susceptibility to complement hyperactivation are implicated in non-STEC-related HUS. However, genetic susceptibility to D+HUS remains largely uncharacterized. Methods:Patients with culture-confirmed STEC diarrhea, identified through the Centers for ... Read more >>

J. Infect. Dis. (The Journal of infectious diseases)
[2018, 217(6):1000-1010]

Cited: 2 times

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Foodborne Disease Outbreaks in the United States: A Historical Overview.

Timothy F Jones, Jane Yackley,

Understanding the epidemiology of foodborne disease outbreaks (FBDOs) is important for informing investigation, control, and prevention methods. We examined annual summary FBDO data in the United States from 1938 to 2015, to help understand the epidemiology of outbreaks over time. Due to changes in reporting procedures, before 1998, the mean ... Read more >>

Foodborne Pathog. Dis. (Foodborne pathogens and disease)
[2018, 15(1):11-15]

Cited: 3 times

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Notes from the Field: Multiple Cases of Seoul Virus Infection in a Household with Infected Pet Rats - Tennessee, December 2016-April 2017.

Mary-Margaret A Fill, Heather Mullins, Andrew Stephen May, Heather Henderson, Shelley M Brown, Cheng-Feng Chiang, Nishi R Patel, John D Klena, Annabelle de St Maurice, Barbara Knust, Stuart T Nichol, John R Dunn, William Schaffner, Timothy F Jones,

MMWR Morb. Mortal. Wkly. Rep. (MMWR. Morbidity and mortality weekly report)
[2017, 66(40):1081-1082]

Cited: 8 times

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Water Quality Survey of Splash Pads After A Waterborne Salmonellosis Outbreak--Tennessee, 2014.

Joshua L Clayton, Judy Manners, Susan Miller, Craig Shepherd, John R Dunn, William Schaffner, Timothy F Jones,

Waterborne outbreaks of salmonellosis are uncommon. The Tennessee Department of Health investigated a salmonellosis outbreak of 10 cases with the only common risk factor being exposure to a single splash pad. Risks included water splashed in the face at the splash pad and no free residual chlorine in the water ... Read more >>

J Environ Health (Journal of environmental health)
[2017, 79(10):8-12]

Cited: 0 times

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Evaluation of a Spotted Fever Group Rickettsia Public Health Surveillance System in Tennessee.

Mary-Margaret A Fill, Abelardo C Moncayo, Karen C Bloch, John R Dunn, William Schaffner, Timothy F Jones,

Spotted fever group (SFG) rickettsioses are endemic in Tennessee, with ∼2,500 cases reported during 2000-2012. Because of this substantial burden of disease, we performed a three-part evaluation of Tennessee's routine surveillance for SFG rickettsioses cases and deaths to assess the system's effectiveness. Tennessee Department of Health (TDH) SFG rickettsioses surveillance ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2017, 97(3):789-794]

Cited: 0 times

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Cryptosporidiosis Outbreak Associated With a Single Hotel.

Mary-Margaret A Fill, Jennifer Lloyd, Tamal Chakraverty, David Sweat, Judy Manners, Katie Garman, Michele C Hlavsa, Dawn M Roellig, John R Dunn, William Schaffner, Timothy F Jones,

We investigated a gastrointestinal illness cluster among persons who attended a baseball tournament (>200 teams) during July 2015. We interviewed representatives of 19 teams; illness was reported among only the 9 (47%) teams that stayed at Hotel A (p < .01). We identified 55 primary cases. A case-control study demonstrated ... Read more >>

J Environ Health (Journal of environmental health)
[2017, 79(9):16-22]

Cited: 2 times

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Novel Clinical and Pathologic Findings in a Heartland Virus-Associated Death.

Mary-Margaret A Fill, Margaret L Compton, Edward C McDonald, Abelardo C Moncayo, John R Dunn, William Schaffner, Julu Bhatnagar, Sherif R Zaki, Timothy F Jones, Wun-Ju Shieh,

We describe an investigation into a Heartland virus (HRTV)-associated death in Tennessee with novel clinical and pathologic findings. HRTV can cause rapidly fatal, widely disseminated infection with multisystem organ failure in patients without substantial comorbidities. We identified viral antigen in multiple organ tissues where it was not detected previously. ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2017, 64(4):510-512]

Cited: 13 times

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Population survey of attitudes and beliefs regarding organic, genetically modified, and irradiated foods.

Jane A Gwira Baumblatt, L Rand Carpenter, Caleb Wiedeman, John R Dunn, William Schaffner, Timothy F Jones,

Sales of organic foods are increasing due to public demand, while genetically modified (GM) and irradiated foods are often viewed with suspicion.The aim of this research was to examine consumer attitudes toward organic, GM and irradiated foods to direct educational efforts regarding their consumption Methods: A telephone survey of 1838 ... Read more >>

Nutr Health (Nutrition and health)
[2017, 23(1):7-11]

Cited: 0 times

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Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries.

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BACKGROUND:Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally. METHODS:Multicentre, international, prospective, cohort study. Self-selected ... Read more >>

BMJ Glob Health (BMJ global health)
[2016, 1(4):e000091]

Cited: 8 times

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Notes from the Field: Measles Outbreak of Unknown Source - Shelby County, Tennessee, April-May 2016.

Mary-Margaret A Fill, David Sweat, Helen Morrow, Alisa Haushalter, Judy C Martin, Tyler Zerwekh, Tamal Chakraverty, Jennifer Kmet, Kevin Morris, Kelly Moore, Marion Kainer, Rendi Murphree, John R Dunn, William Schaffner, Timothy F Jones,

On April 15, 2016, local public health officials in Shelby County, Tennessee, were notified of a positive measles immunoglobulin M (IgM) test for a male aged 18 months (patient A). On April 18, 2016, a second positive measles IgM test was reported for a man aged 50 years (patient B). ... Read more >>

MMWR Morb. Mortal. Wkly. Rep. (MMWR. Morbidity and mortality weekly report)
[2016, 65(38):1039-1040]

Cited: 4 times

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Characteristics of Clusters of Salmonella and Escherichia coli O157 Detected by Pulsed-Field Gel Electrophoresis that Predict Identification of Outbreaks.

Timothy F Jones, Nupur Sashti, Amanda Ingram, Quyen Phan, Hillary Booth, Joshua Rounds, Cyndy S Nicholson, Shaun Cosgrove, Kia Crocker, L Hannah Gould,

Molecular subtyping of pathogens is critical for foodborne disease outbreak detection and investigation. Many clusters initially identified by pulsed-field gel electrophoresis (PFGE) are not confirmed as point-source outbreaks. We evaluated characteristics of clusters that can help prioritize investigations to maximize effective use of limited resources.A multiagency collaboration (FoodNet) collected data ... Read more >>

Foodborne Pathog. Dis. (Foodborne pathogens and disease)
[2016, 13(12):674-678]

Cited: 3 times

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Implementation Of Prescription Drug Monitoring Programs Associated With Reductions In Opioid-Related Death Rates.

Stephen W Patrick, Carrie E Fry, Timothy F Jones, Melinda B Buntin,

Over the past two decades the number of opioid pain relievers sold in the United States rose dramatically. This rise in sales was accompanied by an increase in opioid-related overdose deaths. In response, forty-nine states (all but Missouri) created prescription drug monitoring programs to detect high-risk prescribing and patient behaviors. ... Read more >>

Health Aff (Millwood) (Health affairs (Project Hope))
[2016, 35(7):1324-1332]

Cited: 78 times

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Notes from the Field: Intoxication and Deaths Associated with Ingestion of a Racing Fuel and Carbonated Soft Drink Mixture - Tennessee, January 2016.

Mary-Margaret A Fill, Donna L Seger, John R Dunn, William Schaffner, Timothy F Jones,

In January 2016, the Tennessee Poison Center and Tennessee Department of Health learned of the deaths of two adolescents, and the nonfatal intoxication of two other adolescents, after ingestion of a mixture of racing fuel (approximately 100% methanol) and a carbonated soft drink. The Tennessee Department of Health reviewed medical ... Read more >>

MMWR Morb. Mortal. Wkly. Rep. (MMWR. Morbidity and mortality weekly report)
[2016, 65(22):585-586]

Cited: 0 times

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Challenges to Arboviral Surveillance in Tennessee: Health-Care Providers' Attitudes and Behaviors.

Julie Shaffner, Timothy F Jones, Abelardo C Moncayo,

Surveillance of arboviruses depends on health-care providers' ability to diagnose and report human cases of disease. The purposes of this study were to assess Tennessee providers' 1) self-efficacy toward diagnosis and management, 2) clinical practices, and 3) variation in these measures by provider characteristics. A survey was e-mailed to 13,851 ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2016, 94(6):1330-1335]

Cited: 0 times

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An Economic Evaluation of PulseNet: A Network for Foodborne Disease Surveillance.

Robert L Scharff, John Besser, Donald J Sharp, Timothy F Jones, Gerner-Smidt Peter, Craig W Hedberg,

The PulseNet surveillance system is a molecular subtyping network of public health and food regulatory agency laboratories designed to identify and facilitate investigation of foodborne illness outbreaks. This study estimates health and economic impacts associated with PulseNet. The staggered adoption of PulseNet across the states offers a natural experiment to ... Read more >>

Am J Prev Med (American Journal of Preventive Medicine)
[2016, 50(5 Suppl 1):S66-S73]

Cited: 27 times

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