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Author Thorsten Gehrke

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What Is the Impact of Automated Synovial Cell Counting on Different Aseptic Causes and Periprosthetic Conditions Associated with Revision THA?

Hussein Abdelaziz, Alaa Aljawabra, Markus Rossmann, Calvin Shum Tien, Mustafa Citak, Till Orla Klatte, Thorsten Gehrke,

Studies have suggested that automated synovial cell counting may overestimate the white blood cell (WBC) count, resulting in false positive tests when evaluating patients for the possibility of periprosthetic joint infection (PJI) after THA. However, associations between WBC counts high enough to mimic PJI in patients whose arthroplasties are not ... Read more >>

Clin Orthop Relat Res (Clinical orthopaedics and related research)
[2021, :]

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What Is the Mid-term Survivorship of Infected Rotating-hinge Implants Treated with One-stage-exchange?

Malte Ohlmeier, Fadi Alrustom, Mustafa Citak, Jochen Salber, Thorsten Gehrke, Jannik Frings,

<h4>Background</h4>Despite the growing number of studies reporting on periprosthetic joint infection (PJI), there is little information on one-stage exchange arthroplasty for the revision of infected rotating-hinge prostheses, which can be among the most difficult PJI presentations to treat.<h4>Questions/purposes</h4>After one-stage direct exchange revision for an infected rotating-hinge TKA prosthesis, and using ... Read more >>

Clin Orthop Relat Res (Clinical orthopaedics and related research)
[2021, 479(12):2714-2722]

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Dislocation of a McMinn-Like Prosthesis with Distinctive Metallosis and Fracture of the Os Ilium.

Peter Caspar Bünemann, Stefan Luck, Malte Ohlmeier, Thorsten Gehrke, Tobias Malte Ballhause,

Osteoarthritis of the hip joint (coxarthrosis) is the most common hip disease in adults. Since the 1960s, total hip arthroplasty (THA) has made great progress and is nowadays one of the most frequently used procedures in orthopedic surgery. Different bearing concepts exist in various implant designs. A metal-on-metal bearing can ... Read more >>

Case Rep Orthop (Case reports in orthopedics)
[2021, 2021:6151679]

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Septic Failure After One-Stage Exchange for Prosthetic Joint Infection of the Hip: Microbiological Implications.

Iman Godarzi Bakhtiari, Georges Vles, Sophia-Marlene Busch, Lars Frommelt, Thorsten Gehrke, Jochen Salber, Mustafa Citak,

<h4>Background</h4>The microbiological implications of septic failure after 1-stage exchange for prosthetic joint infection (PJI) of the hip remain unclear.<h4>Methods</h4>Information was gathered on comorbidities, previous procedures, preoperative and postoperative microbiology results, methods of detection, and antibiotic resistance patterns, for all patients, who developed septic failure after 1-stage exchange for PJI of ... Read more >>

J Arthroplasty (The Journal of arthroplasty)
[2021, :]

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Allograft Chip Incorporation in Acetabular Reconstruction: Multiscale Characterization Revealing Osteoconductive Capacity.

Sebastian Butscheidt, Simon von Kroge, Julian Stürznickel, Frank Timo Beil, Thorsten Gehrke, Klaus Püschel, Michael Amling, Michael Hahn, Tim Rolvien,

<h4>Background</h4>Impacted bone-grafting with morselized allograft chips is commonly used to reconstruct acetabular bone defects in revision total hip arthroplasty (THA). While the overall clinical outcome of this procedure is described to be excellent, the microstructural basis and histological determinants of allograft incorporation remained to be further elucidated.<h4>Methods</h4>The acetabula of 23 ... Read more >>

J Bone Joint Surg Am (The Journal of bone and joint surgery. American volume)
[2021, 103(21):1996-2005]

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Resection of the proximal femur during one-stage revision for infected hip arthroplasty : risk factors and effectiveness.

Hussein Abdelaziz, Michael Schröder, Calvin Shum Tien, Kahled Ibrahim, Thorsten Gehrke, Jochen Salber, Mustafa Citak,

<h4>Aims</h4>One-stage revision hip arthroplasty for periprosthetic joint infection (PJI) has several advantages; however, resection of the proximal femur might be necessary to achieve higher success rates. We investigated the risk factors for resection and re-revisions, and assessed complications and subsequent re-revisions.<h4>Methods</h4>In this single-centre, case-control study, 57 patients who underwent one-stage ... Read more >>

Bone Joint J (The bone & joint journal)
[2021, 103-B(11):1678-1685]

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The Clinical Outcome of Different Total Knee Arthroplasty Designs in One-Stage Revision for Periprosthetic Infection.

Malte Ohlmeier, Fadi Alrustom, Mustafa Citak, Tim Rolvien, Thorsten Gehrke, Jannik Frings,

<h4>Background</h4>Despite the growing number of studies reporting on the best surgical treatment in the management of periprosthetic joint infection, there are no robust data regarding the type of infected prosthesis before any kind of exchange arthroplasty. To overcome these shortcomings, we asked the following questions: (1) What is the survivorship ... Read more >>

J Arthroplasty (The Journal of arthroplasty)
[2021, :]

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Risk factors for mortality following one-stage septic hip arthroplasty - a case-control study.

Sophia-Marlene Busch, Mustafa Citak, Mustafa Akkaya, Felix Prange, Thorsten Gehrke, Philip Linke,

<h4>Purpose</h4>Despite good clinical outcomes and a high success rate, there is a comparatively high mortality after one stage septic exchange of total hip arthroplasty. The aim of this study was to identify risk factors for mortality in the hospitalization period after one-stage septic exchange of THA.<h4>Methods</h4>We retrospectively analyzed in our ... Read more >>

Int Orthop (International orthopaedics)
[2021, :]

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Diagnostic utility of open biopsy in patients with two culture-negative aspirations in the diagnostic work-up of periprosthetic joint infection.

Ianiv Klaber, Fabian Scholz, Mustafa Citak, Akos Zahar, Thorsten Gehrke, Carl Haasper, Nael Hawi, Christian Lausmann,

<h4>Introduction</h4>Different approaches have been proposed for bacterial identification in patients with a suspected periprosthetic joint infection (PJI). If a one-stage procedure is considered, a higher rate of preoperative bacterial identification can be achieved if biopsy is included in the diagnostic work-up. The performance of open biopsy (OB) in the context ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2021, :]

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Correction to: Short-term mortality after primary and revision total joint arthroplasty: a single-center analysis of 103,560 patients.

Felix Prange, Alina Seifert, Pongsiri Piakong, Thorsten Gehrke, Dario Guttowski, Sophia-Marlene Busch, Jochen Salber, Mustafa Citak,

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2021, 141(8):1433]

Cited: 1 time

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Tranexamic acid is safe and effective in patients with heterozygous factor V Leiden mutation during total joint arthroplasty.

Ali Levent, Ozkan Kose, Philip Linke, Thorsten Gehrke, Mustafa Citak,

<h4>Introduction</h4>Patients with an inherent hypercoagulable state are at a higher risk of venous thromboembolism (VTE) following total joint arthroplasty (TJA). Further administration of tranexamic acid (TXA) during TJA may increase the risk of VTE in these high-risk patients. There is no study that specifically analyzes the safety and efficacy of ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2021, :]

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Which International Consensus Meeting Preoperative Minor Criteria is the Most Accurate Marker for the Diagnosis of Periprosthetic Joint Infection in Hip and Knee Arthroplasty?

Ali Levent, Michael E Neufeld, Pongsiri Piakong, Christian Lausmann, Thorsten Gehrke, Mustafa Citak,

<h4>Background</h4>The accurate preoperative diagnosis of periprosthetic joint infection (PJI) is critical. The aim of this study was to evaluate the diagnostic accuracy and performance of the 2018 International Consensus Meeting (ICM) preoperative minor criteria for the diagnosis of chronic PJI in total hip and knee arthroplasty.<h4>Methods</h4>We retrospectively reviewed 260 patients ... Read more >>

J Arthroplasty (The Journal of arthroplasty)
[2021, 36(11):3728-3733]

Cited: 1 time

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Blood transfusion and venous thromboembolism trends and risk factors in primary and aseptic revision total hip and knee arthroplasties: A nationwide investigation of 736,061 cases.

Elke Jeschke, Mustafa Citak, Andreas M Halder, Karl-Dieter Heller, Fritz U Niethard, Peter Schräder, Josef Zacher, Hanna Leicht, Jürgen Malzahn, Christian Günster, Thorsten Gehrke,

<h4>Background</h4>Over the last years, new transfusion guidelines and pharmaceuticals have been introduced in primary and revision total hip and knee arthroplasty (P-THA, P-TKA, R-THA, R-TKA). In the US, a substantial decrease in transfusions has been observed in recent years. Little data exists on the subject in Europe. In this context ... Read more >>

Orthop Traumatol Surg Res (Orthopaedics & traumatology, surgery & research : OTSR)
[2021, :102987]

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[Manual addition of antibiotics to industrial bone cement mixes : Investigations of the dry mix in the cement cartridge during manual admixture to polymer-active substance mixtures].

Mustafa Citak, Stefan Luck, Philip Linke, Thorsten Gehrke, Klaus-Dieter Kühn,

<h4>Background</h4>Periprosthetic infection (PPI) is a rare but serious complication. An elementary component of the therapy of PPI is the use of bone cement with the addition of antibiotics. For targeted therapy, manual mixing of antibiotics with industrially produced bone cement mixtures is often necessary. Possible problems resulting from manual mixing have ... Read more >>

Orthopade (Der Orthopade)
[2021, :]

Cited: 1 time

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Total Hip Arthroplasty in a Patient with Mucopolysaccharidosis Type IVB.

Yannick N T van den Eeden, Niklas Unter Ecker, Holger Kleinertz, Thorsten Gehrke, Tobias M Ballhause,

<i>Introduction</i>. Morquio syndrome or mucopolysaccharidosis (MPS) type IV is a rare autosomal recessive lysosomal storage disease, characterized by abnormal metabolism of glycosaminoglycans associated with specific skeletal deformities, also known as dysostosis multiplex. <i>Case Presentation</i>. We present the case of a 23-year-old patient with advanced osteonecrosis of the femoral head (ONFH) ... Read more >>

Case Rep Orthop (Case reports in orthopedics)
[2021, 2021:5584408]

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Variability in stem taper surface topography affects the degree of corrosion and fretting in total hip arthroplasty.

Kilian Elia Stockhausen, Christoph Riedel, Alex Victoria Belinski, Dorothea Rothe, Thorsten Gehrke, Felix Klebig, Matthias Gebauer, Michael Amling, Mustafa Citak, Björn Busse,

Degradation at the modular head-neck interface in total hip arthroplasty (THA) is predominately expressed in the form of corrosion and fretting, potentially causing peri-prosthetic failure by adverse reactions to metal debris. This retrieval study aimed to quantify variations in stem taper surface topographies and to assess the influence on the ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):9348]

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Is there still room for improvement in the diagnosis, treatment and prevention of bone and joint infection?

Thomas Bauer, Eric Senneville, Thorsten Gehrke,

Orthop Traumatol Surg Res (Orthopaedics & traumatology, surgery & research : OTSR)
[2021, 107(4):102928]

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A novel radiological classification system of the distal femur.

Mustafa Citak, Ali Levent, Eduardo M Suero, Kristof Rademacher, Sophia-Marlene Busch, Thorsten Gehrke,

<h4>Introduction</h4>In our previous studies, we were able to identify anatomical differences as a predictor for aseptic loosening following primary and revision surgery with the use of rotating hinge prosthesis. This study was performed to answer following question: can a novel radiological classification system of the distal femur be identified?<h4>Materials and methods</h4>A ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2021, :]

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What to Do When Revision Procedures Fail to Prevent Recurrent Hip Dislocation in THA? A Novel Simple Technique for Selected Patients.

Hans Mau, Mustafa Citak, Thorsten Gehrke, Hussein Abdelaziz,

Failure to achieve postoperative stability is disappointing for both surgeons and patients after revision total hip arthroplasty. In particular, when available revision options have been exhausted. We describe our modification of previously reported surgical techniques without revising any component in a high-risk female patient with persistent hip dislocation despite multiple ... Read more >>

Arthroplast Today (Arthroplasty today)
[2021, 8:89-91]

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Risk Factors for Aseptic Loosening After Total Knee Arthroplasty with a Rotating-Hinge Implant: A Case-Control Study.

Ali Levent, Eduardo M Suero, Thorsten Gehrke, Mustafa Citak,

<h4>Background</h4>Successful results have been reported in association with the use of a rotating-hinge prosthesis for primary total knee arthroplasty (TKA). The objective of the present study was to identify risk factors for aseptic loosening in patients who underwent primary TKA with rotating-hinge knee prostheses.<h4>Methods</h4>The records of 1,235 patients who underwent ... Read more >>

J Bone Joint Surg Am (The Journal of bone and joint surgery. American volume)
[2021, 103(6):517-523]

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High re-revision rate following one-stage exchange for streptococcal periprosthetic joint infection of the hip.

Malte Ohlmeier, Insa Jachczik, Mustafa Citak, Thorsten Gehrke, Nael Hawi, Carl Haasper, Hussein Abdelaziz,

<h4>Introduction</h4>This study was undertaken to analyse the outcome of 1-stage exchange in the management of streptococcal periprosthetic joint infection (PJI) of the hip at a single hospital.<h4>Methods</h4>We identified 30 patients with a streptococcal PJI of the hip who had been treated by 1-stage exchange at our hospital between 2002 and ... Read more >>

Hip Int (Hip international : the journal of clinical and experimental research on hip pathology and therapy)
[2021, :1120700021991467]

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Distinct clonal lineages and within-host diversification shape invasive Staphylococcus epidermidis populations.

Anna Both, Jiabin Huang, Minyue Qi, Christian Lausmann, Samira Weißelberg, Henning Büttner, Susanne Lezius, Antonio Virgilio Failla, Martin Christner, Marc Stegger, Thorsten Gehrke, Sharmin Baig, Mustafa Citak, Malik Alawi, Martin Aepfelbacher, Holger Rohde,

S. epidermidis is a substantial component of the human skin microbiota, but also one of the major causes of nosocomial infection in the context of implanted medical devices. We here aimed to advance the understanding of S. epidermidis genotypes and phenotypes conducive to infection establishment. Furthermore, we investigate the adaptation ... Read more >>

PLoS Pathog (PLoS pathogens)
[2021, 17(2):e1009304]

Cited: 5 times

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What Is the Dislocation and Revision Rate of Dual-mobility Cups Used in Complex Revision THAs?

Niklas Unter Ecker, Hakan Kocaoğlu, Akos Zahar, Carl Haasper, Thorsten Gehrke, Mustafa Citak,

<h4>Background</h4>Dual-mobility cups have been shown to reduce the dislocation risk after THA. Although dual-mobility cups can be a useful strategy to mitigate against recurrent dislocation after revision surgery, few clinical studies have focused on the results of complex revision THAs with extensive bone and soft-tissue loss or in patients who ... Read more >>

Clin Orthop Relat Res (Clinical orthopaedics and related research)
[2021, 479(2):280-285]

Cited: 1 time

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Reply to the Letter to Editor by Aliyev et al.: Think about the distal femoral anatomy differences!

Mustafa Citak, Ali Levent, Eduardo M Suero, Kristof Rademacher, Sophia-Marlene Busch, Thorsten Gehrke,

Int Orthop (International orthopaedics)
[2021, 45(3):809-810]

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Results of the first 1,000 procedures after resumption of elective orthopedic services following COVID-19 pandemic: Experiences of a high-volume arthroplasty center.

Thorsten Gehrke, Philip Linke, Amir Sandiford, Christian Lausmann, Mustafa Citak,

<h4>Objectives</h4>This study aims to investigate the effectiveness of a screening questionnaire to identify high-risk patients for novel coronavirus-2019 (COVID-19) among those undergoing elective orthopedic surgery.<h4>Patients and methods</h4>Between May 4th, 2020 and June 11th, 2020, a total of 1,021 consecutive patients (492 males, 529 females; mean age: 62.3±15.1 years; range, 13 ... Read more >>

Jt Dis Relat Surg (Joint diseases and related surgery)
[2021, 32(1):3-9]

Cited: 1 time

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