Full Text Journal Articles by
Author Thomas Reinhard

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Acute Closed-Angle Glaucoma-an Ophthalmological Emergency.

Simone Nüssle, Thomas Reinhard, Jan Lübke,

<h4>Background</h4>Acute closed-angle glaucoma has an incidence of 2.2-4.1 cases per 100 000 persons per year in Europe. It is an ophthalmological emergency in which markedly elevated intraocular pressure can damage vision permanently. Because the acute symptoms are not always clearly referable to the eyes, patients often present to physicians who ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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A Decellularized Human Limbal Scaffold for Limbal Stem Cell Niche Reconstruction.

Naresh Polisetti, Benjamin Roschinski, Ursula Schlötzer-Schrehardt, Philip Maier, Günther Schlunck, Thomas Reinhard,

The transplantation of ex vivo expanded limbal epithelial progenitor cells (LEPCs) on amniotic membrane or fibrin gel is an established therapeutic strategy to regenerate the damaged corneal surface in patients with limbal stem cell deficiency (LSCD), but the long-term success rate is restricted. A scaffold with niche-specific structure and extracellular ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2021, 22(18):]

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Considerations When Using a Statistical Learning Model to Predict Corneal Edema Resolution-Reply.

Daniel Zander, Thomas Reinhard, Katrin Wacker,

JAMA Ophthalmol (JAMA ophthalmology)
[2021, :]

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NEGATIVE VESSEL REMODELING IN STARGARDT DISEASE QUANTIFIED WITH VOLUME-RENDERED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Michael Reich, Michelle Dreesbach, Daniel Boehringer, Julia Schottenhamml, Esteban Gehring, Hendrik P N Scholl, Nadja Inglin, Hansjuergen Agostini, Thomas Reinhard, Wolf A Lagrèze, Richard F Spaide, Clemens Lange, Peter M Maloca,

<h4>Purpose</h4>To quantify retinal vasculature changes in Stargardt disease1 (STGD1) with volume-rendered optical coherence tomography angiography.<h4>Methods</h4>Optical coherence tomography angiography volumes from healthy subjects and two subgroups of patients with STGD1 with the presence/absence of definitely decreased autofluorescence areas were compared. Optical coherence tomography angiography vessel surface area and vessel volume were ... Read more >>

Retina (Retina (Philadelphia, Pa.))
[2021, 41(9):1948-1957]

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Ectopic thyroid tissue in the iris: a case report.

Helena Wagner, Claudia Auw-Hädrich, Martin Werner, Thomas Reinhard,

<h4>Background</h4>Ectopic thyroid tissue in the iris, also known as a thyroid glandular epithelial choristoma of the iris, has only been described twice in the literature. In both cases it remained asymptomatic.<h4>Case presentation</h4>A 67-year-old female patient presented for the first time in mid-2017 with corneal endothelial decompensation, with a history of ... Read more >>

BMC Ophthalmol (BMC ophthalmology)
[2021, 21(1):314]

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Trends in Surgical Glaucoma Treatment in Germany Between 2006 and 2018.

Jan Luebke, Daniel Boehringer, Alexandra Anton, Moritz Daniel, Thomas Reinhard, Stefan Lang,

<h4>Background/aims</h4>Surgical procedures in ophthalmology underlie variations over different time periods and are strongly dependent on the technical process and the invention of innovative surgical techniques. Especially, in glaucoma surgery a lot of surgical devices and techniques have been introduced during the last years. Until now, the use of these newer ... Read more >>

Clin Epidemiol (Clinical epidemiology)
[2021, 13:581-592]

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Clinical Course of Different Types of Immune Reactions following Keratoplasty.

Philip Keye, Thabo Lapp, Daniel Böhringer, Sonja Heinzelmann, Philip Maier, Thomas Reinhard,

<h4>Background</h4>Immune-mediated corneal graft rejection (IR) is a leading cause of corneal graft failure. The endothelium, stroma, epithelium, or a combination can be affected. Little is known about the long-term outcomes of different types of IR.<h4>Methods</h4>We reviewed the medical records of all keratoplasties that had been performed at our eye centre ... Read more >>

Klin Monbl Augenheilkd (Klinische Monatsblatter fur Augenheilkunde)
[2021, :]

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Time- and Stimulus-Dependent Characteristics of Innate Immune Cells in Organ-Cultured Human Corneal Tissue.

Xinyu Zhuang, Günther Schlunck, Julian Wolf, Dennis-Dominik Rosmus, Tim Bleul, Ren Luo, Daniel Böhringer, Peter Wieghofer, Clemens Lange, Thomas Reinhard, Thabo Lapp,

<h4>Purpose</h4>The pattern of immune cells infiltrating the corneal stroma has been extensively studied in mice, but data on human tissue have been far less elaborate. To further characterize the number and differentiation state of resident immune cells in organ-cultured human corneal tissue, we employed a comprehensive bioinformatic deconvolution (xCell) of ... Read more >>

J Innate Immun (Journal of innate immunity)
[2021, :1-14]

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Impact of the SARS-CoV-2 pandemic on ophthalmic care in Germany.

Lars-Olof Hattenbach, Peter Heinz, Nicolas Feltgen, Hans Hoerauf, Thomas Kohnen, Siegfried Priglinger, Werner Bachmann, Johannes Rieks, Nicole Eter, Thomas Reinhard,

<h4>Background</h4>Survey by the commission for cross-sectoral ophthalmology, as a joint commission of the German Ophthalmological Society (DOG) and the Professional Association of German Ophthalmologists (BVA) on the effects of the SARS-CoV‑2 pandemic on ophthalmological patient care in Germany.<h4>Methods</h4>Online-based survey.<h4>Results</h4>A total of 1190 questionnaires were (partly) answered. With respect to outpatient care ... Read more >>

Ophthalmologe (Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft)
[2021, 118(Suppl 2):166-175]

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Hyperosmolar Eye Drops for Diurnal Corneal Edema in Fuchs' Endothelial Dystrophy: A Double-Masked, Randomized Controlled Trial.

Daniel B Zander, Daniel Böhringer, Marianne Fritz, Viviane Grewing, Philip C Maier, Thabo Lapp, Thomas Reinhard, Katrin Wacker,

<h4>Purpose</h4>The Eye Drops for Early Morning-Associated Swelling (EDEMAS) trial assessed the efficacy of hyperosmolar eye drops on corneal edema resolution.<h4>Design</h4>Double-masked, randomized controlled trial of hyperosmolar eye drops.<h4>Participants</h4>Participants with Fuchs' dystrophy scheduled for Descemet membrane endothelial keratoplasty.<h4>Methods</h4>One eye was randomized to hyperosmolar eye drops (treatment); the fellow eye was randomized to ... Read more >>

Ophthalmology (Ophthalmology)
[2021, :]

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[Online examination course instead of classroom teaching: adaptation of medical student teaching during the COVID-19 pandemic].

Cornelius Wiedenmann, Katrin Wacker, Daniel Böhringer, Philip Maier, Thomas Reinhard,

<h4>Background</h4>The coronavirus disease 2019 (COVID-19) pandemic restricted face-to-face interactions of medical students and teachers.<h4>Objective</h4>To develop and evaluate an online course for ophthalmology examination techniques for medical students and to determine the impact of the course on the practical objective structured clinical examination (OSCE).<h4>Material and methods</h4>The online examination course was developed ... Read more >>

Ophthalmologe (Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft)
[2021, :]

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[Crosslinking and Keratoconus].

Stefan J Lang, Philip Maier, Thomas Reinhard,

Keratoconus leads to a progressive protrusion and thinning of the cornea. In order to stop this, corneal crosslinking can be performed if the progression of the disease is proven. Crosslinking according to the "Dresden protocol" includes abrasion of the corneal epithelium, application of riboflavin eye drops and irradiation with UV-A ... Read more >>

Klin Monbl Augenheilkd (Klinische Monatsblatter fur Augenheilkunde)
[2021, 238(6):733-747]

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Vertical Scrolling Axis of Corneal Endothelial Grafts for Descemet Membrane Endothelial Keratoplasty.

Katrin Wacker, Marianne Fritz, Viviane Grewing, Philip C Maier, Thomas Reinhard,

<h4>Purpose</h4>Heterogeneity in scrolling behavior of Descemet membrane endothelial keratoplasty (DMEK) grafts complicates DMEK surgery. This prospective observational study assessed scrolling axes of DMEK grafts relative to the donor's eye.<h4>Methods</h4>The eye bank randomly marked the rim of corneoscleral donor buttons during trephination and recorded the position relative to the donor's axis. ... Read more >>

Cornea (Cornea)
[2021, 40(4):497-501]

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Predicting Edema Resolution After Descemet Membrane Endothelial Keratoplasty for Fuchs Dystrophy Using Scheimpflug Tomography.

Daniel Zander, Viviane Grewing, Andreas Glatz, Thabo Lapp, Philip C Maier, Thomas Reinhard, Katrin Wacker,

<h4>Importance</h4>Predicting the extent of corneal edema resolution after Descemet membrane endothelial keratoplasty (DMEK) may help in preoperative decision-making by identifying patients who may benefit from restoring endothelial function.<h4>Objective</h4>To develop and validate a predictive model for edema resolution after DMEK using Scheimpflug tomographic imaging.<h4>Design, setting, and participants</h4>Two prospective studies recruited participants ... Read more >>

JAMA Ophthalmol (JAMA ophthalmology)
[2021, 139(4):423-430]

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Genotype-phenotype correlation in von Hippel-Lindau disease.

Michael Reich, Sabine Jaegle, Elke Neumann-Haefelin, Jan-Helge Klingler, Charlotte Evers, Moritz Daniel, Felicitas Bucher, Franziska Ludwig, Simone Nuessle, Julia Kopp, Daniel Boehringer, Thomas Reinhard, Wolf A Lagrèze, Clemens Lange, Hansjuergen Agostini, Stefan J Lang,

<h4>Background/aims</h4>Retinal haemangioblastomas (RH) remain a major cause of visual impairment in patients with von Hippel-Lindau (VHL) disease. Identification of genotype-phenotype correlation is an important prerequisite for better management, treatment and prognosis.<h4>Methods</h4>Retrospective, single-centre cohort study of 200 VHL patients. Genetic data and date of onset of RH, central nervous system haemangioblastomas ... Read more >>

Acta Ophthalmol (Acta ophthalmologica)
[2021, :]

Cited: 1 time

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[Orbital hemorrhage during diving].

Markus Gruber, Thomas Reinhard, Philip Maier,

Ophthalmologe (Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft)
[2021, 118(3):283-284]

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Estimating the Incidence of Conjunctivitis by Comparing the Frequency of Google Search Terms With Clinical Data: Retrospective Study.

Paola Kammrath Betancor, Linda Tizek, Alexander Zink, Thomas Reinhard, Daniel Böhringer,

<h4>Background</h4>Infectious conjunctivitis is contagious and may lead to an outbreak. Prevention systems can help to avoid an outbreak.<h4>Objective</h4>We aimed to evaluate if Google search data on conjunctivitis and associated terms can be used to estimate the incidence and if the data can provide an estimation for outbreaks.<h4>Methods</h4>We obtained Google search ... Read more >>

JMIR Public Health Surveill (JMIR public health and surveillance)
[2021, 7(3):e22645]

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Rotational alignment of corneal endothelial grafts and risk of graft detachment after Descemet membrane endothelial keratoplasty: a double-masked pseudo-randomized study.

Marianne Fritz, Viviane Grewing, Markus Gruber, Helena Wagner, Daniel Zander, Thabo Lapp, Stefan J Lang, Sonja Heinzelmann-Mink, Philip C Maier, Thomas Reinhard, Katrin Wacker,

<h4>Purpose</h4>The posterior cornea is rotationally asymmetric, and Descemet membrane endothelial keratoplasty (DMEK) grafts preferentially scroll vertically. This prospective study assessed whether graft attachment after DMEK differed depending on the rotational alignment of the donor graft in the recipient eye.<h4>Methods</h4>Pseudo-randomization and blinding of the graft orientation in the recipient's eye were ... Read more >>

Acta Ophthalmol (Acta ophthalmologica)
[2021, :]

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A decellularized human corneal scaffold for anterior corneal surface reconstruction.

Naresh Polisetti, Anke Schmid, Ursula Schlötzer-Schrehardt, Philip Maier, Stefan J Lang, Thorsten Steinberg, Günther Schlunck, Thomas Reinhard,

Allogenic transplants of the cornea are prone to rejection, especially in repetitive transplantation and in scarred or highly vascularized recipient sites. Patients with these ailments would particularly benefit from the possibility to use non-immunogenic decellularized tissue scaffolds for transplantation, which may be repopulated by host cells in situ or in ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):2992]

Cited: 1 time

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Ophthalmological Interventions Not Covered.

Daniel Böhringer, Markus Gruber, Thomas Reinhard,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(5):68]

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[Orbital trauma by ocular prostheses during scuba diving].

Markus Gruber, Thomas Reinhard, Philip Maier,

Ophthalmologe (Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft)
[2021, 118(3):287]

Cited: 1 time

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Survey of Rejection Prophylaxis Following Suture Removal in Penetrating Keratoplasty in Germany.

Sonja Heinzelmann, Daniel Böhringer, Philip Christian Maier, Berthold Seitz, Claus Cursiefen, Anna-Karina B Maier, Tina Dietrich-Ntoukas, Gerd Geerling, Arne Viestenz, Norbert Pfeiffer, Thomas Reinhard,

<h4>Background</h4>Penetrating keratoplasty (PK) gets more and more reserved to cases of increasing complexity. In such cases, ocular comorbidities may limit graft survival following PK. A major cause for graft failure is endothelial graft rejection. Suture removal is a known risk factor for graft rejection. Nevertheless, there is no evidence-based regimen ... Read more >>

Klin Monbl Augenheilkd (Klinische Monatsblatter fur Augenheilkunde)
[2021, 238(5):591-597]

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[Subepithelial Opacities in the Corneal Stroma after Foreign Body Removal].

Laurenz Johannes Bernhard Pauleikhoff, Thomas Reinhard, Philip Christian Maier,

Klin Monbl Augenheilkd (Klinische Monatsblatter fur Augenheilkunde)
[2021, :]

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Influence of Pulse Wave Velocity on Atherosclerosis and Blood Flow Reversal in the Aorta: A 4-Dimensional Flow Magnetic Resonance Imaging Study in Acute Stroke Patients and Matched Controls.

Thomas Wehrum, Iulius Dragonu, Christoph Strecker, Anja Hennemuth, Jürgen Hennig, Thomas Reinhard, Andreas Harloff,

<h4>Background</h4>Aortic stiffness is associated with a higher incidence of cardiovascular events including stroke. The primary aim of this study was to evaluate whether increased pulse wave velocity (PWV), a marker of stiffness, is an independent predictor of aortic atheroma. The secondary aim was to test whether increased PWV reinforces retrograde ... Read more >>

J Thorac Imaging (Journal of thoracic imaging)
[2021, :]

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[Chronification of malignant glaucoma after cataract surgery].

Cornelius Wiedenmann, Stefaniya Boneva, Alexandra Anton, Thomas Reinhard, Jan Lübke,

The occurrence of malignant glaucoma several years after cataract surgery is a very rare delayed complication. An increasing myopic shift can be an early hint for the formation. A surgical intervention is often inevitable; however, intraocular pressure can also be successfully managed with conservative treatment as in the case described. Therefore, treatment ... Read more >>

Ophthalmologe (Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft)
[2021, 118(2):175-179]

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