Full Text Journal Articles by
Author Thomas Loew

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Successful weight loss reduces endothelial activation in individuals with severe obesity participating in a multimodal weight loss program.

Sabine J M Sag, Christina Strack, Judith Zeller, Margareta Mohr, Thomas Loew, Claas Lahmann, Lars S Maier, Marcus Fischer, Andrea Baessler,

<h4>Introduction</h4>Endothelial dysfunction is a very common finding in obesity and metabolic syndrome. The aim of our study was to investigate if longterm weight reduction (WR) success may reverse endothelial activation in individuals with severe obesity participating in a multimodal WR program.<h4>Methods</h4>Participants with obesity (øBMI 40.3 ±7.5 kg/m<sup>2</sup>) underwent a standardized ... Read more >>

Obes Res Clin Pract (Obesity research & clinical practice)
[2021, 15(3):249-255]

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A Multimodal Stress-Prevention Program Supplemented by Telephone-Coaching Sessions to Reduce Perceived Stress among German Farmers: Results from a Randomized Controlled Trial.

Marita Stier-Jarmer, Cornelia Oberhauser, Dieter Frisch, Götz Berberich, Thomas Loew, Carina Schels-Klemens, Birgit Braun, Angela Schuh,

This study compared the effectiveness of a 12-day stress-prevention program (SGS) supplemented by individualized, structured, four-session telephone-coaching to that of an SGS without telephone-coaching in entrepreneurs from the green professions presenting with increased stress levels. All participants went through the SGS before being randomized either to the telephone-coaching group (TC) ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(24):]

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L-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond-Blackfan Anemia Registry.

Adrianna Vlachos, Evangelia Atsidaftos, Mohammad Lutfi Lababidi, Ellen Muir, Zora R Rogers, Waseem Alhushki, Jonathan Bernstein, Bertil Glader, Barbara Gruner, Helge Hartung, Christine Knoll, Thomas Loew, Grzegorz Nalepa, Anupama Narla, Arun R Panigrahi, Colin A Sieff, Kelly Walkovich, Jason E Farrar, Jeffrey M Lipton,

<h4>Background</h4>Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure syndrome characterized by anemia, short stature, congenital anomalies, and cancer predisposition. Most cases are due to mutations in genes encoding ribosomal proteins (RP) leading to RP haploinsufficiency. Effective treatments for the anemia of DBA include chronic red cell transfusions, long-term corticosteroid ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2020, 67(12):e28748]

Cited: 1 time

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SNP dependent modulation of circulating miRNAs from the miR25/93/106 cluster in patients undergoing weight loss.

Stephanie Müller, Stefan Wallner, Gerd Schmitz, Thomas Loew, Thomas Stempfl, Christoph Möhle, Christina Strack, Sabine Sag, Andrea Baessler, Marcus Fischer,

BACKGROUND:Diet induced weight loss represents an intervention for obesity to prevent associated diseases. However there is considerable inter-individual variation. Single nucleotide polymorphisms (SNPs) and plasma miRNA might be contributing factors. We therefore hypothesized that changes in the miRNA pattern during weight loss depend on the SNP genotype. METHODS:Plasma miRNA profiles ... Read more >>

Gene (Gene)
[2020, 753:144787]

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[Inpatient psychosomatics in times of the coronavirus].

Thomas H Loew, Maximilian Krinninger, Christian Kettler,

The current coronavirus 2019 (COVID-19) pandemic presents psychosomatic clinics with new challenges. In order that psychotherapists in private practice can also obtain a picture for their patients, this article deals with the core aspects of hygiene. There are three fundamental patterns of care and provisions by the institutions that can ... Read more >>

Psychotherapeut (Berl) (Psychotherapeut)
[2020, :1-6]

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Why are some cases not on track? An item analysis of the Assessment for Signal Cases during inpatient psychotherapy.

Thomas Probst, Maria Kleinstäuber, Michael J Lambert, Karin Tritt, Christoph Pieh, Thomas H Loew, Reiner W Dahlbender, Jaime Delgadillo,

Within the Routine Outcome Monitoring system "OQ-Analyst," the questionnaire "Assessment for Signal Cases" (ASC) supports therapists in detecting potential reasons for not-on-track trajectories. Factor analysis and a machine learning algorithm (LASSO with 10-fold cross-validation) were applied, and potential predictors of not-on-track classifications were tested using logistic multilevel modeling methods. The ... Read more >>

Clin Psychol Psychother (Clinical psychology & psychotherapy)
[2020, 27(4):559-566]

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[The "popular saint" Therese of Konnersreuth and her stigmata : An historical example for the interaction of psyche and religiosity].

Birgit Braun, Joachim Demling, Thomas H Loew,

<h4>Background</h4>In present times, we see ourselves confronted by the challenge of engaging increasingly diverse views of the world, god and healing in a constructive dialogue. Consequently, it is important to research into the contrary effects of religiosity on the human psyche.<h4>Methods</h4>Original- and literary medical historian research RESULTS: Gottfried Ewald (1888-1963), a psychiatric ... Read more >>

Nervenarzt (Der Nervenarzt)
[2020, 91(1):64-72]

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Placebo Economics: A Systematic Review About the Economic Potential of Utilizing the Placebo Effect.

Jens Hamberger, Karin Meissner, Thilo Hinterberger, Thomas Loew, Katja Weimer,

Background: Recent research shows that placebo mechanisms can be utilized in ethical and legal ways such as in open-label conditions, when patients know that they receive placebos, and through psychological interventions aiming to optimize patients' expectations. Showing that placebo interventions are also cost-efficient could improve their acceptability. Objective: To review ... Read more >>

Front Psychiatry (Frontiers in psychiatry)
[2019, 10:653]

Cited: 2 times

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The brain's resonance with breathing-decelerated breathing synchronizes heart rate and slow cortical potentials.

Thilo Hinterberger, Nike Walter, Christopher Doliwa, Thomas Loew,

Numerous methods for enhancing consciousness and well-being emphasize the role of breathing. For the first time, we have investigated the link between body rhythms and slow cortical brain dynamics during paced breathing. We present physiological data from 37 participants who performed paced breathing sessions with respiration rates (RRs) from 6 ... Read more >>

J Breath Res (Journal of breath research)
[2019, 13(4):046003]

Cited: 2 times

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The adipo-fibrokine activin A is associated with metabolic abnormalities and left ventricular diastolic dysfunction in obese patients.

Judith Zeller, Carolin Krüger, Valeria Lamounier-Zepter, Sabine Sag, Christina Strack, Margareta Mohr, Thomas Loew, Gerd Schmitz, Lars Maier, Marcus Fischer, Andrea Baessler,

<h4>Aims</h4>Left ventricular diastolic dysfunction (LVDD) is common in obese subjects, and a relationship between epicardial adipose tissue (EAT), increased adipocytokines, and cardiovascular diseases has been reported. This study sought to examine as to whether the adipo-fibrokine activin A is a link between increased EAT, the metabolic syndrome (MetS), and LVDD ... Read more >>

ESC Heart Fail (ESC heart failure)
[2019, 6(2):362-370]

Cited: 6 times

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[500 Years of Reformation: The History of Martin Luther's Pathography and its Ethical Implications].

Birgit Braun, Thomas Loew,

<b>Introduction</b> In the context of the 500th anniversary of the Reformation, it is time to take a survey of the history of Martin Luther's (1483-1546) pathography and to deduce possible conclusions from it for psychiatric practice. <b>Results</b> In a 1035-page work written in German between 1937 and 1941, the Dane ... Read more >>

Fortschr Neurol Psychiatr (Fortschritte der Neurologie-Psychiatrie)
[2017, 85(10):592-604]

Cited: 0 times

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Relation Between Obesity, Metabolic Syndrome, Successful Long-Term Weight Reduction, and Right Ventricular Function.

Judith Zeller, Christina Strack, Sabine Fenk, Margareta Mohr, Thomas Loew, Gerd Schmitz, Lars Maier, Marcus Fischer, Andrea Baessler,

This study sought to examine the relationships between right ventricular (RV) function and geometry, morbid obesity with and without the metabolic syndrome, and the effect of long-term weight loss. Obese (n = 153, BMI 41.2 ± 8.7 kg/m(2)) and healthy non-obese control subjects (n = 38, BMI 25.5 ± 3.3 ... Read more >>

Int Heart J (International heart journal)
[2016, 57(4):441-448]

Cited: 8 times

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Depressed Mood Differentially Mediates the Relationship between Pain Intensity and Pain Disability Depending on Pain Duration: A Moderated Mediation Analysis in Chronic Pain Patients.

Thomas Probst, Susanne Neumeier, Jürgen Altmeppen, Michael Angerer, Thomas Loew, Christoph Pieh,

Research has shown that pain is associated with disability and that depressed mood mediates the relationship between pain and disability. The question of whether duration of pain moderates these effects was addressed in this cross-sectional study with 356 chronic pain patients. A simple mediation model replicated the notion that depressed ... Read more >>

Pain Res Manag (Pain research & management)
[2016, 2016:3204914]

Cited: 4 times

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Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis.

Zhongbo Yang, Thomas Loew, Richard D Hammer,

Haematopoietic abnormalities associated with tacrolimus are relatively rare with reversible pure red cell aplasia being the most common. We report for the first time, to our best knowledge, tacrolimus therapy associated with bone marrow fibrosis, abnormal megakaryocytosis, and dyserythopoiesis in a 17-year-old male treated with tacrolimus for nephrotic syndrome. ... Read more >>

Clin Case Rep (Clinical case reports)
[2015, 3(7):664-668]

Cited: 1 time

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[The ICD-10 Symptom Rating (ISR): validation of the depression scale in a clinical sample].

Wolfram Alexis Brandt, Thomas Loew, Friedrich von Heymann, Godehard Stadtmüller, Alexander Georgi, Michael Tischinger, Frederik Strom, Friederike Mutschler, Karin Tritt,

The ICD-10 Symptom Rating (ISR) 1 measures the severity of psychiatric disorders with 29 items on 5 subscales as comprehensively as possible. The following syndromes are measured: Depressive syndrome, anxiety syndrome, obsessive-compulsive syndrome, Somatoform syndrome, eating disorder syndrome as well as additional items that cover various mental syndromes, and an ... Read more >>

Psychother Psychosom Med Psychol (Psychotherapie, Psychosomatik, medizinische Psychologie)
[2015, 65(6):234-237]

Cited: 1 time

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Successful weight reduction improves left ventricular diastolic function and physical performance in severe obesity.

Sabine Fenk, Marcus Fischer, Christina Strack, Gerd Schmitz, Thomas Loew, Claas Lahmann, Andrea Baessler,

Obesity and the metabolic syndrome (MetS) are risk factors for left ventricular diastolic dysfunction (LVDD). However, little is known about the impact of successful weight reduction (WR) on diastolic function and physical performance.Obese subjects (øBMI 40.2 ± 8.6 kg/m(2)) underwent a 1-year WR program comprising diet and lifestyle components. Echocardiography ... Read more >>

Int Heart J (International heart journal)
[2015, 56(2):196-202]

Cited: 11 times

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Significant variation in salivation by short-term suggestive intervention: a randomized controlled cross-over clinical study.

Maximilian Satzl, Albrecht Schmierer, Florian Zeman, Gottfried Schmalz, Thomas Loew,

<h4>Introduction</h4>Most dental procedures require a dry working environment. Although many evaporative drying methods are available, an additional reduction of salivary flow would often be helpful.<h4>Methods</h4>This prospective randomized cross-over study compares salivary production in 31 volunteers during direct, indirect, and non-suggestive (control group) intervention. Overall, each volunteer underwent four salivation measurements, ... Read more >>

Head Face Med (Head & face medicine)
[2014, 10:49]

Cited: 1 time

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Extreme deviations from expected recovery curves and their associations with therapeutic alliance, social support, motivation, and life events in psychosomatic in-patient therapy.

Thomas Probst, Michael J Lambert, Thomas H Loew, Reiner W Dahlbender, Karin Tritt,

<h4>Objectives</h4>Within the clinical support tools (CST) of the OQ-Analyst, the "Assessment for Signal Cases" (ASC) evaluates the therapeutic alliance, social support, motivation, and life events. We investigated whether the ASC covers domains of importance in treatment weeks with extreme deviations from expected recovery curves (ERCs).<h4>Methods</h4>Psychosomatic in-patients were monitored weekly with ... Read more >>

Psychother Res (Psychotherapy research : journal of the Society for Psychotherapy Research)
[2015, 25(6):714-723]

Cited: 9 times

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[Non-completion of insurance-funded outpatient psychotherapy: frequency, risk factors, outcome].

Uwe Altmann, Werner W Wittmann, Andrés Steffanowski, Friedrich von Heymann, Ellen Bruckmayer, Irmgard Pfaffinger, Emma Auch, Thomas Loew, Dietmar Kramer, Andrea Fembacher, Rolf Steyer, Anna Zimmermann, Bernhard M Strauß,

<h4>Objective</h4>Because premature discontinuation of psychotherapy limits the effectiveness of the interventions, in a naturalistic design we examined the prevalence, predictors, and outcome of premature discontinuation.<h4>Methods</h4>The sample included N = 584 patients with various mental disorders. Risk factors were identified using regression analysis. As outcome Patient Health Questionnaire scales were considered. We compared ... Read more >>

Psychiatr Prax (Psychiatrische Praxis)
[2014, 41(6):305-312]

Cited: 2 times

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Evaluation of medical research performance--position paper of the Association of the Scientific Medical Societies in Germany (AWMF).

Christoph Herrmann-Lingen, Edgar Brunner, Sibylle Hildenbrand, Thomas H Loew, Tobias Raupach, Claudia Spies, Rolf-Detlef Treede, Christian-Friedrich Vahl, Hans-Jürgen Wenz,

<h4>Objective</h4>The evaluation of medical research performance is a key prerequisite for the systematic advancement of medical faculties, research foci, academic departments, and individual scientists' careers. However, it is often based on vaguely defined aims and questionable methods and can thereby lead to unwanted regulatory effects. The current paper aims at ... Read more >>

Ger Med Sci (German medical science : GMS e-journal)
[2014, 12:Doc11]

Cited: 9 times

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How does the ICD-10 symptom rating (ISR) with four items assess depression compared to the BDI-II? A validation study.

Wolfram A Brandt, Thomas Loew, Friedrich von Heymann, Godehard Stadtmüller, Michael Tischinger, Frederik Strom, Judith Molfenter, Alexander Georgi, Karin Tritt,

<h4>Objective</h4>The "ICD-10 Symptom-Rating" (ISR) is a novel 29-item self-rating questionnaire with scales for the assessment of depression, anxiety, OCD, somatisation and eating disorders and additional items. This study aims at the validation of the depression subscale.<h4>Methods</h4>Based on a sample of 1844 depressed inpatients, the ISR was correlated with the Beck-Depression-Inventory-II ... Read more >>

J Affect Disord (Journal of affective disorders)
[2015, 173:143-145]

Cited: 4 times

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Providing patient progress feedback and clinical support tools to therapists: is the therapeutic process of patients on-track to recovery enhanced in psychosomatic in-patient therapy under the conditions of routine practice?

Thomas Probst, Michael J Lambert, Reiner W Dahlbender, Thomas H Loew, Karin Tritt,

<h4>Objectives</h4>In previous studies of patients on-track to recovery (OT) involving therapists receiving only patient progress feedback without clinical support tools (CST) inconsistent results were found. Possible effects of combining patient progress feedback with CST on OT patients remain unclear.<h4>Methods</h4>At intake (t1), 252 patients of two in-patient psychosomatic clinics were randomized ... Read more >>

J Psychosom Res (Journal of psychosomatic research)
[2014, 76(6):477-484]

Cited: 8 times

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Effectiveness of a multimodal treatment program for somatoform pain disorder.

Christoph Pieh, Susanne Neumeier, Thomas Loew, Jürgen Altmeppen, Michael Angerer, Volker Busch, Claas Lahmann,

Chronic pain conditions are highly prevalent, with somatoform pain disorder accounting for a large proportion. However, the psychological forms of treatment currently used achieve only small to medium effect sizes. This retrospective study investigated the effectiveness of a 5-week multimodal pain program for patients with somatoform pain disorder. The diagnosis ... Read more >>

Pain Pract (Pain practice : the official journal of World Institute of Pain)
[2014, 14(3):E146-51]

Cited: 8 times

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Evaluation of a salutogenetic concept for inpatient psychosomatic treatment.

Thilo Hinterberger, Jochen Auer, Stephanie Schmidt, Thomas Loew,

The increase of psychosomatic disorders due to cultural changes requires enhanced therapeutic models. This study investigated a salutogenetic treatment concept for inpatient psychosomatic treatment, based on data from more than 11000 patients of a psychosomatic clinic in Germany. The clinic aims at supporting patients' health improvement by fostering values such ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2013, 2013:735731]

Cited: 1 time

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Primary Prevention Programme for Burnout-Endangered Teachers: Follow-Up Effectiveness of a Combined Group and Individual Intervention of AFA Breathing Therapy.

Katja Goetz, Thomas Loew, Regina Hornung, Laura Cojocaru, Claas Lahmann, Karin Tritt,

Background. Early retirement of teachers due to burnout is frequent in Germany. In this study short- and medium-term effects of AFA breathing therapy were evaluated. Methods. This study was designed as a longitudinal controlled intervention design with four points of measurements: before assessment (T1), after intervention (T2), three months (follow ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2013, 2013:798260]

Cited: 1 time

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