Full Text Journal Articles by
Author Thomas Lehmann

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Wound Closure After Port Implantation-a Randomized Controlled Trial Comparing Tissue Adhesive and Intracutaneous Suturing.

Saskia Witting, Maja Ingwersen, Thomas Lehmann, René Aschenbach, Niklas Eckardt, Jürgen Zanow, René Fahrner, Stephan Lotze, Reinhard Friedel, Mark Lenz, Claudia Schmidt, Diana Miguel, Laine Ludriksone, Ulf Teichgräber,

<h4>Background</h4>Wound healing after pectoral port implantation is a major factor determining the success or failure of the procedure. Infection and wound dehiscence can endanger the functionality of the port system and impede chemotherapy. The cosmetic result is important for patient satisfaction as well.<h4>Methods</h4>From August 2015 to July 2017, adult patients ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Do closed waste containers lead to less air contamination than opened? A clinical case study at Jena University Hospital, Germany.

Franziskus Büchner, Marc Hoffman, Ute-Helke Dobermann, Birgit Edel, Thomas Lehmann, Frank Kipp,

Nosocomial infections are a growing challenge at hospitals. This clinical study aimed to investigate the influence of waste container construction ((open (O), closed (C), and hands-free opening (HF)) on microbial air contamination in a hospital setting. The results are intended to help develop guidelines for waste containers for the collection ... Read more >>

Waste Manag (Waste management (New York, N.Y.))
[2021, 136:11-17]

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Predictors of Treatment Requirements in Women with Gestational Diabetes: A Retrospective Analysis.

Friederike Weschenfelder, Karolin Lohse, Thomas Lehmann, Ekkehard Schleußner, Tanja Groten,

The diagnosis of gestational diabetes is usually very stressful for pregnant women, especially because they fear that insulin treatment may become necessary. Knowledge about personal risk factors predicting the probability of insulin treatment could therefore help to improve acceptance of the diagnosis and therapy adherence. The aim of this study ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(19):]

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Predictors of a successful vaginal delivery in women with type 1 diabetes: a retrospective analysis of 20 years.

Friederike Weschenfelder, Eva Herrmann, Thomas Lehmann, Ekkehard Schleußner, Christof Kloos, Wilgard Battfeld, Tanja Groten,

<h4>Purpose</h4>To evaluate the independent factors associated with the success of a trial of vaginal birth (TVB) in women with type 1 diabetes. Despite all therapeutic efforts and technological innovations, rates of caesarean sections (CS) in pregnant women with type 1 diabetes remain unchanged above 60%. Our aim was to point ... Read more >>

Arch Gynecol Obstet (Archives of gynecology and obstetrics)
[2021, :]

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The squirrel is in the detail: Anatomy and morphometry of the tail in Sciuromorpha (Rodentia, Mammalia).

Rebecca Hofmann, Thomas Lehmann, Dan L Warren, Irina Ruf,

In mammals, the caudal vertebrae are certainly among the least studied elements of their skeleton. However, the tail plays an important role in locomotion (e.g., balance, prehensility) and behavior (e.g., signaling). Previous studies largely focused on prehensile tails in Primates and Carnivora, in which certain osteological features were selected and ... Read more >>

J Morphol (Journal of morphology)
[2021, :]

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Heart Rate Variability Analyses in Parkinson's Disease: A Systematic Review and Meta-Analysis.

Konstantin G Heimrich, Thomas Lehmann, Peter Schlattmann, Tino Prell,

Recent evidence suggests that the vagus nerve and autonomic dysfunction play an important role in the pathogenesis of Parkinson's disease. Using heart rate variability analysis, the autonomic modulation of cardiac activity can be investigated. This meta-analysis aims to assess if analysis of heart rate variability may indicate decreased parasympathetic tone ... Read more >>

Brain Sci (Brain sciences)
[2021, 11(8):]

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The effect of influenza and pneumococcal vaccination in the elderly on health service utilisation and costs: a claims data-based cohort study.

Josephine Storch, Carolin Fleischmann-Struzek, Norman Rose, Thomas Lehmann, Anna Mikolajetz, Srikanth Maddela, Mathias W Pletz, Christina Forstner, Ole Wichmann, Julia Neufeind, Monique Vogel, Konrad Reinhart, Horst Christian Vollmar, Antje Freytag, ,

<h4>Background</h4>To date, cost-effectiveness of influenza and pneumococcal vaccinations was assumed in several health economic modelling studies, but confirmation by real-world data is sparse. The aim of this study is to assess the effects on health care utilisation and costs in the elderly using real-world data on both, outpatient and inpatient ... Read more >>

Eur J Health Econ (The European journal of health economics : HEPAC : health economics in prevention and care)
[2021, :]

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Role of Concomitant Coronary Artery Bypass Grafting in Valve Surgery for Infective Endocarditis.

Mahmoud Diab, Thomas Lehmann, Carolyn Weber, Georgi Petrov, Maximilian Luehr, Payam Akhyari, Sems-Malte Tugtekin, P Christian Schulze, Marcus Franz, Martin Misfeld, Michael A Borger, Klaus Matschke, Thorsten Wahlers, Artur Lichtenberg, Christian Hagl, Torsten Doenst,

<h4>Background</h4>It is current practice to perform concomitant coronary artery bypass grafting (CABG) in patients with infective endocarditis (IE) who have relevant coronary artery disease (CAD). However, CABG may add complexity to the operation. We aimed to investigate the impact of concomitant CABG on perioperative outcomes in patients undergoing surgery for ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(13):]

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Effectiveness of two types of palliative home care in cancer and non-cancer patients: A retrospective population-based study using claims data.

Markus Krause, Bianka Ditscheid, Thomas Lehmann, Maximiliane Jansky, Ursula Marschall, Winfried Meißner, Friedemann Nauck, Ulrich Wedding, Antje Freytag,

<h4>Background</h4>Comparative effectiveness of different types of palliative homecare is sparsely researched internationally-despite its potential to inform necessary decisions in palliative care infrastructure development. In Germany, specialized palliative homecare delivered by multi-professional teams has increased in recent years and factors beyond medical need seem to drive its involvement and affect the ... Read more >>

Palliat Med (Palliative medicine)
[2021, 35(6):1158-1169]

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Is there an HbA1c Threshold for Symptoms of Chronic Hyperglycemia?

Nicolle Müller, Thomas Lehmann, Ulrich Alfons Müller, Christof Kloos,

<h4>Aims of the study</h4>The minimum therapeutic goal regarding metabolic control for people with diabetes mellitus is the "absence of symptoms of hyperglycemia." However, it is uncertain whether a level of HbA1c can be defined that guarantees the absence of these symptoms. The aim was to define an HbA1c threshold above ... Read more >>

Exp Clin Endocrinol Diabetes (Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association)
[2021, :]

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Ivacaftor Reduces Inflammatory Mediators in Upper Airway Lining Fluid From Cystic Fibrosis Patients With a G551D Mutation: Serial Non-Invasive Home-Based Collection of Upper Airway Lining Fluid.

Jochen G Mainz, Christin Arnold, Kara Wittstock, Uta-Christina Hipler, Thomas Lehmann, Carlos Zagoya, Franziska Duckstein, Helmut Ellemunter, Julia Hentschel,

In cystic fibrosis (CF) therapy, the recent approval of CF-transmembrane conductance regulator (CFTR) channel modulators is considered to be the major breakthrough. However, the current first-line approach based mainly on pulmonary function to measure effects of the novel therapy, tested by forced expiratory volumes in one second (FEV<sub>1</sub>), provides restricted ... Read more >>

Front Immunol (Frontiers in immunology)
[2021, 12:642180]

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Microglia-mediated phagocytosis of apoptotic nuclei is impaired in the adult murine hippocampus after stroke.

Max Rudolph, Christian W Schmeer, Madlen Günther, Florus Woitke, Carolin Kathner-Schaffert, Lina Karapetow, Julia Lindner, Thomas Lehmann, Gustav Jirikowski, Otto W Witte, Christoph Redecker, Silke Keiner,

Following stroke, neuronal death takes place both in the infarct region and in brain areas distal to the lesion site including the hippocampus. The hippocampus is critically involved in learning and memory processes and continuously generates new neurons. Dysregulation of adult neurogenesis may be associated with cognitive decline after a ... Read more >>

Glia (Glia)
[2021, 69(8):2006-2022]

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Trajectories of depression in sepsis survivors: an observational cohort study.

Monique Boede, Jochen S Gensichen, James C Jackson, Fiene Eißler, Thomas Lehmann, Sven Schulz, Juliana J Petersen, Florian P Wolf, Tobias Dreischulte, Konrad F R Schmidt,

<h4>Background</h4>Advances in critical care medicine have led to a growing number of critical illness survivors. A considerable part of them suffers from long-term sequelae, also known as post-intensive care syndrome. Among these, depressive symptoms are frequently observed. Depressive symptom trajectories and associated factors of critical illness survivors have rarely been ... Read more >>

Crit Care (Critical care (London, England))
[2021, 25(1):161]

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Circadian rhythm and gestational diabetes: working conditions, sleeping habits and lifestyle influence insulin dependency during pregnancy.

Friederike Weschenfelder, Karolin Lohse, Thomas Lehmann, Ekkehard Schleußner, Tanja Groten,

<h4>Objective</h4>Management of gestational diabetes (GDM) is currently changing toward a more personalized approach. There  is a growing number of GDM patients requiring only a single dose of basal insulin at night to achieve glucose control. Well-known risk factors like obesity, parity and family history have been associated with GDM treatment ... Read more >>

Acta Diabetol (Acta diabetologica)
[2021, 58(9):1177-1186]

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Impact of assessing patient-reported outcomes with mobile apps on patient-provider interaction.

Yomei Shaw, Delphine S Courvoisier, Almut Scherer, Adrian Ciurea, Thomas Lehmann, Veronika K Jaeger, Ulrich A Walker, Axel Finckh,

<h4>Objective</h4>To explore the effect of apps measuring patient-reported outcomes (PROs) on patient-provider interaction in the rheumatic diseases in an observational setting.<h4>Methods</h4>Patients in the Swiss Clinical Quality Management in Rheumatic Diseases Registry were offered mobile apps (iDialog and COmPASS) to track disease status between rheumatology visits using validated PROs (Rheumatoid Arthritis ... Read more >>

RMD Open (RMD open)
[2021, 7(1):]

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Clinical and economic outcomes of a collaborative cardiology care program.

Felix Sebastian Wicke, Bianka Ditscheid, Thorben Breitkreuz, Anastasiya Glushan, Thomas Lehmann, Kateryna Karimova, Olga Anastasia Sawicki, Monique Vogel, Antje Freytag, Martin Beyer,

<h4>Objectives</h4>We evaluated a collaborative care program aimed at improving cooperation among general practitioners (GPs) and cardiologists in Baden-Wuerttemberg, Germany. The program focused on improving care for patients with chronic cardiac conditions.<h4>Study design</h4>We conducted a retrospective cohort study. The observation period was 2 years.<h4>Methods</h4>The study was based on claims data and ... Read more >>

Am J Manag Care (The American journal of managed care)
[2021, 27(4):e114-e122]

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Self-Reported Nonadherence to Medication Is Not Associated with Health-Related Quality of Life in Parkinson's Disease.

Hannah M Zipprich, Sarah Mendorf, Thomas Lehmann, Tino Prell,

Nonadherence is a growing issue in the treatment of Parkinson's disease (PD). Many factors are known to influence nonadherence, but little is known about the influence of quality of life (QoL). Detailed clinical data were obtained from 164 patients with PD using the Parkinson's Disease Questionnaire-39 (PDQ-39) and the German ... Read more >>

Brain Sci (Brain sciences)
[2021, 11(2):]

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'Desire for more analgesic treatment': pain and patient-reported outcome after paediatric tonsillectomy and appendectomy.

Ulrike M Stamer, Kyra Bernhart, Thomas Lehmann, Maria Setzer, Frank Stüber, Marcus Komann, Winfried Meissner,

<h4>Background</h4>Insufficiently treated pain after paediatric appendectomy and tonsillectomy is frequent. We aimed to identify variables associated with poor patient-reported outcomes.<h4>Methods</h4>This analysis derives from the European PAIN OUT infant registry providing information on perioperative pharmacological data and patient-reported outcomes 24 h after surgery. Variables associated with the endpoint 'desire for more ... Read more >>

Br J Anaesth (British journal of anaesthesia)
[2021, 126(6):1182-1191]

Cited: 3 times

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Monitoring of the Progression of the Perioperative Serum Lactate Concentration Improves the Accuracy of the Prediction of Acute Mesenteric Ischemia Development After Cardiovascular Surgery.

Henning Mothes, Jana Wickel, Christoph Sponholz, Thomas Lehmann, Mirko Kaluza, Juergen Zanow, Torsten Doenst,

<h4>Objectives</h4>To examine the sensitivity and specificity of perioperative lactate gradients for the prediction of subsequent acute mesenteric ischemia development in patients undergoing cardiovascular surgery.<h4>Design</h4>Retrospective, single-center, case-control study.<h4>Setting</h4>University hospital.<h4>Participants</h4>The study comprised 108 (1.15%) patients with acute mesenteric ischemia who were selected from 9,385 patients who underwent cardiovascular surgery and were matched ... Read more >>

J Cardiothorac Vasc Anesth (Journal of cardiothoracic and vascular anesthesia)
[2021, 35(6):1792-1799]

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Endogenous indole-3-acetamide levels contribute to the crosstalk between auxin and abscisic acid, and trigger plant stress responses in Arabidopsis.

Marta-Marina Pérez-Alonso, Paloma Ortiz-García, José Moya-Cuevas, Thomas Lehmann, Beatriz Sánchez-Parra, Robert G Björk, Sazzad Karim, Mohammad R Amirjani, Henrik Aronsson, Mark D Wilkinson, Stephan Pollmann,

The evolutionary success of plants relies to a large extent on their extraordinary ability to adapt to changes in their environment. These adaptations require that plants balance their growth with their stress responses. Plant hormones are crucial mediators orchestrating the underlying adaptive processes. However, whether and how the growth-related hormone ... Read more >>

J Exp Bot (Journal of experimental botany)
[2021, 72(2):459-475]

Cited: 2 times

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Phenotyping in the era of genomics: MaTrics – a digital character matrix to document mammalian phenotypic traits coded numerically

Clara Stefen, Franziska Wagner, Marika Asztalos, Peter Giere, Peter Grobe, Michael Hiller, Rebecca Hofmann, Maria Jähde, Ulla Lächele, Thomas Lehmann, Sylvia Ortmann, Benjamin Peters, Irina Ruf, Christian Schiffmann, Nadja Thier, Gabi Unterhitzenberger, Lars Vogt, Matthias Rudolf, Peggy Wehner, Heiko Stuckas,

A new and uniquely structured matrix of mammalian phenotypes, MaTrics ( Ma mmalian Tr aits for Comparative Genom ics ) is presented in a digital form. By focussing on mammalian species for which genome assemblies are available, MaTrics provides an interface between mammalogy and comparative genomics. MaTrics was developed as ... Read more >>

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Preventive effects of influenza and pneumococcal vaccination in the elderly - results from a population-based retrospective cohort study.

Norman Rose, Josephine Storch, Anna Mikolajetz, Thomas Lehmann, Konrad Reinhart, Mathias W Pletz, Christina Forstner, Horst Christian Vollmar, Antje Freytag, Carolin Fleischmann-Struzek,

Influenza and pneumococcal vaccinations are recommended in the elderly to reduce life-threatening complications like sepsis. Protection may be reduced with increasing age. We aimed to assess the effectiveness of both vaccines in the elderly by performing a retrospective cohort study of 138,877 individuals aged ≥60 y in Germany, who were insured ... Read more >>

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2021, 17(6):1844-1852]

Cited: 1 time

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Contributing Factors to Perinatal Outcome in Pregnancies with Gestational Diabetes-What Matters Most? A Retrospective Analysis.

Friederike Weschenfelder, Friederike Hein, Thomas Lehmann, Ekkehard Schleußner, Tanja Groten,

The aim of diabetes care of pregnant women with gestational diabetes mellitus (GDM) is to attain pregnancy outcomes including rates of large-for-gestational-age (LGA) newborns, pre-eclampsia, C-sections (CS) and other neonatal outcomes similar to those of the non-GDM pregnant population. Obesity and excessive weight gain during pregnancy have been shown to ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(2):]

Cited: 1 time

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Image quality and safety of automated carbon dioxide digital subtraction angiography in femoropopliteal lesions: Results from a randomized single-center study.

F Bürckenmeyer, A Schmidt, I Diamantis, Thomas Lehmann, A Malouhi, T Franiel, J Zanow, U K M Teichgräber, R Aschenbach,

<h4>Purpose</h4>To evaluate the image quality and the safety of automated carbon dioxide (CO<sub>2</sub>) digital subtraction angiography (DSA).<h4>Materials and methods</h4>Fifty patients receiving DSA for femoropopliteal peripheral arterial disease (PAD) were enrolled in this single-center prospective study. All patients received iodinated contrast media (ICM) and CO<sub>2</sub> as a contrast agent in the ... Read more >>

Eur J Radiol (European journal of radiology)
[2021, 135:109476]

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Exploring the ontogenetic development of the inner ear in Aardvarks.

Emilie Berlioz, Raphaël Cornette, Nicolas Lenoir, Mathieu D Santin, Thomas Lehmann,

The aardvark is the last living Tubulidentata, an order of afrotherian mammals. Afrotheria is supported strongly by molecular analyses, yet sparingly by morphological characters. Moreover, the biology of the aardvark remains incompletely known. The inner ear, and its ontogeny in particular, has not been studied in details yet, though it ... Read more >>

J Anat (Journal of anatomy)
[2021, 238(5):1128-1142]

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