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Author Tharakeswara K Bathala

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Freehand Versus Grid-Based Transperineal Prostate Biopsy: A Comparison of Anatomic Region Yield and Complications.

Ahmet Urkmez, Cihan Demirel, Muammer Altok, Tharakeswara K Bathala, Daniel D Shapiro, John W Davis,

<h4>Purpose</h4>The freehand (FH) technique of transperineal (TP) prostate biopsy using commercialized needle access systems facilitates a reduction in anesthesia requirements from general to local or local/sedation. We sought to compare the efficacy and complication rates of the FH method with those of the standard grid-based (GB) method.<h4>Materials and methods</h4>The GB ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001902]

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Efficacy and Safety of Bevacizumab Plus Erlotinib in Patients with Renal Medullary Carcinoma.

Andrew J Wiele, Devaki Shilpa Surasi, Priya Rao, Kanishka Sircar, Xiaoping Su, Tharakeswara K Bathala, Amishi Y Shah, Eric Jonasch, Vince D Cataldo, Giannicola Genovese, Jose A Karam, Christopher G Wood, Nizar M Tannir, Pavlos Msaouel,

<h4>Purpose</h4>To assess the efficacy and safety of bevacizumab plus erlotinib in patients with RMC.<h4>Methods</h4>We retrospectively reviewed the records of patients with RMC treated with bevacizumab plus erlotinib at our institution.<h4>Results</h4>Ten patients were included in the study. Two patients achieved a partial response (20%) and seven patients achieved stable disease (70%). ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(9):]

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The impact and collateral damage of COVID-19 on prostate MRI and guided biopsy operations: Society of Abdominal Radiology Prostate Cancer Disease-Focused Panel survey analysis.

Devaki Shilpa S Surasi, Xuemei Wang, Tharakeswara K Bathala, Hyunsoo Hwang, Sandeep Arora, Antonio C Westphalen, Silvia D Chang, Baris Turkbey,

The Coronavirus disease 2019 (COVID-19) pandemic has significantly affected health care systems throughout the world. A Qualtrics survey was targeted for radiologists around the world to study its effect on the operations of prostate MRI studies and biopsies. Descriptive statistics were reported. A total of 60 complete responses from five ... Read more >>

Abdom Radiol (NY) (Abdominal radiology (New York))
[2021, :]

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Lenvatinib with or Without Everolimus in Patients with Metastatic Renal Cell Carcinoma After Immune Checkpoint Inhibitors and Vascular Endothelial Growth Factor Receptor-Tyrosine Kinase Inhibitor Therapies.

Andrew J Wiele, Tharakeswara K Bathala, Andrew W Hahn, Lianchun Xiao, Munevver Duran, Jeremy A Ross, Eric Jonasch, Amishi Y Shah, Matthew T Campbell, Pavlos Msaouel, Nizar M Tannir,

<h4>Introduction</h4>Lenvatinib (Len) plus everolimus (Eve) is an approved therapy for metastatic renal cell carcinoma (mRCC) after first-line vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFR-TKIs), but limited data exist on the efficacy of Len ± Eve after progression on immune checkpoint inhibitors (ICIs) and VEGFR-TKIs.<h4>Methods</h4>We retrospectively reviewed the records of ... Read more >>

Oncologist (The oncologist)
[2021, 26(6):476-482]

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Outcomes of patients with metastatic renal cell carcinoma with sarcomatoid dedifferentiation to immune checkpoint inhibitors.

Jad Chahoud, Pavlos Msaouel, Jeremy A Ross, Barrett Z McCormick, Tharakeswara K Bathala, Jianjun Gao, Robert Horn, Lianchun Xiao, Kanishka Sircar, Matthew T Campbell, Amishi Y Shah, Sangeeta Goswami, Amado J Zurita, Eric Jonasch, Surena F Matin, Christopher G Wood, Jose A Karam, Padmanee Sharma, Nizar M Tannir,

<h4>Introduction</h4>Metastatic renal cell carcinoma with sarcomatoid dedifferentiation (sRCC) is associated with poor survival outcomes. We aimed to analyze the efficacy and safety of immune checkpoint inhibitors (ICI) in patients with sRCC comparing clear-cell (sccRCC) to non-clear cell epithelial histology (snccRCC).<h4>Methods</h4>We performed retrospective analysis of sRCC patients who received ICI at ... Read more >>

Urol Oncol (Urologic oncology)
[2021, 39(2):134.e9-134.e16]

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Predictors of urinary toxicity with MRI-assisted radiosurgery for low-dose-rate prostate brachytherapy.

David Boyce-Fappiano, Tharakeswara K Bathala, Rong Ye, Dario Pasalic, Olsi Gjyshi, Todd A Pezzi, Sonal S Noticewala, Gwendolyn J McGinnis, Sean Maroongroge, Deborah A Kuban, Quynh-Nhu Nguyen, Sean E McGuire, Karen E Hoffman, Seungtaek Choi, Chad Tang, Rajat J Kudchadker, Steven J Frank,

<h4>Purpose</h4>MRI-assisted radiosurgery (MARS) is a modern technique for prostate brachytherapy that provides superior soft tissue contrast. The purpose of this analysis was to evaluate treatment planning factors associated with urinary toxicity, particularly damage to the membranous urethra (MUL) and external urethral sphincter (EUS), after MARS.<h4>Material and methods</h4>We retrospectively reviewed 227 ... Read more >>

Brachytherapy (Brachytherapy)
[2020, 19(5):574-583]

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Quality comparison between three-dimensional T2-weighted SPACE and two-dimensional T2-weighted turbo spin echo magnetic resonance images for the brachytherapy planning evaluation of prostate and periprostatic anatomy.

Tharakeswara K Bathala, Aradhana M Venkatesan, Jingfei Ma, Priyadarshini Bhosale, Wei Wei, Rajat J Kudchadker, Jihong Wang, Mitchell S Anscher, Chad Tang, Teresa L Bruno, Steven J Frank, Janio Szklaruk,

<h4>Purpose</h4>The purpose of this study was to compare an isotropic three-dimensional (3D) T2-weighted sequence sampling perfection with application-optimized contrasts by using flip angle evolution (SPACE) with an axial two-dimensional T2-weighted turbo spin echo (TSE) sequence with regard to overall image quality and the delineation of normal prostate and periprostatic anatomy ... Read more >>

Brachytherapy (Brachytherapy)
[2020, 19(4):484-490]

Cited: 1 time

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Comparison of Diagnostic Utility of Fluciclovine PET/CT Versus Pelvic Multiparametric MRI for Prostate Cancer in the Pelvis in the Setting of Rising PSA After Initial Treatment.

Bo Chen, Tharakeswara K Bathala, Guofang Xu, Ajalaya Teyateeti, Brian F Chapin, Chad Tang, Shi-Ming Tu, Homer A Macapinlac, Yang Lu,

<h4>Purpose</h4>The aim of this study was to investigate the imaging diagnostic performance of F-fluciclovine PET/CT and pelvic multiparametric MRI (mpMRI) for prostate cancer in the setting of rising PSA after initial treatment, with a focus on detection of recurrent and metastatic prostate cancer in the pelvis.<h4>Methods</h4>Patients with prostate cancer who ... Read more >>

Clin Nucl Med (Clinical nuclear medicine)
[2020, 45(5):349-355]

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Patterns of metastases of prostatic ductal adenocarcinoma.

Weranja K B Ranasinghe, Nathan A Brooks, Mohamed A Elsheshtawi, John W Davis, Tharakeswara K Bathala, Chad Tang, Patricia Troncoso, Ana Aparicio, Shi-Ming Tu, Louis L Pisters, Brian F Chapin,

<h4>Background</h4>The current study was conducted to investigate the patterns of metastases in men with metastatic prostatic ductal adenocarcinoma (DAC) and recurrence patterns after therapy.<h4>Methods</h4>All patients with a new diagnosis of DAC with de novo metastases and those with localized disease who developed metastases after treatment and were treated at the ... Read more >>

Cancer (Cancer)
[2020, 126(16):3667-3673]

Cited: 2 times

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Increased Frequency of Mesorectal and Perirectal LN Involvement in T4 Prostate Cancers.

Ibrahim Abu-Gheida, Tharakeswara K Bathala, J Alberto Maldonado, Mishal Khan, Mitchell S Anscher, Steven Jay Frank, Seungtaek Choi, Quynh-Nhu Nguyen, Karen E Hoffman, Sean Eric McGuire, Minsoo Kim, Deborah A Kuban, Ana Aparicio, Brian Francis Chapin, Chad Tang,

<h4>Purpose</h4>Patients with prostate cancer presenting with advanced T stage, mainly T4, might have a unique pattern of nodal failure and disease involvement that is not typically covered when local therapy is offered. We attempted to identify common sites of nodal disease presentation and failure for patients presenting with cT4 prostate ... Read more >>

Int J Radiat Oncol Biol Phys (International journal of radiation oncology, biology, physics)
[2020, 107(5):982-985]

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Variability of the Positive Predictive Value of PI-RADS for Prostate MRI across 26 Centers: Experience of the Society of Abdominal Radiology Prostate Cancer Disease-focused Panel.

Antonio C Westphalen, Charles E McCulloch, Jordan M Anaokar, Sandeep Arora, Nimrod S Barashi, Jelle O Barentsz, Tharakeswara K Bathala, Leonardo K Bittencourt, Michael T Booker, Vaughn G Braxton, Peter R Carroll, David D Casalino, Silvia D Chang, Fergus V Coakley, Ravjot Dhatt, Steven C Eberhardt, Bryan R Foster, Adam T Froemming, Jurgen J Fütterer, Dhakshina M Ganeshan, Mark R Gertner, Lori Mankowski Gettle, Sangeet Ghai, Rajan T Gupta, Michael E Hahn, Roozbeh Houshyar, Candice Kim, Chan Kyo Kim, Chandana Lall, Daniel J A Margolis, Stephen E McRae, Aytekin Oto, Rosaleen B Parsons, Nayana U Patel, Peter A Pinto, Thomas J Polascik, Benjamin Spilseth, Juliana B Starcevich, Varaha S Tammisetti, Samir S Taneja, Baris Turkbey, Sadhna Verma, John F Ward, Christopher A Warlick, Andrew R Weinberger, Jinxing Yu, Ronald J Zagoria, Andrew B Rosenkrantz,

Background Prostate MRI is used widely in clinical care for guiding tissue sampling, active surveillance, and staging. The Prostate Imaging Reporting and Data System (PI-RADS) helps provide a standardized probabilistic approach for identifying clinically significant prostate cancer. Despite widespread use, the variability in performance of prostate MRI across practices remains ... Read more >>

Radiology (Radiology)
[2020, 296(1):76-84]

Cited: 7 times

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Collaborative Learning in Radiology: From Peer Review to Peer Learning and Peer Coaching.

Alison L Chetlen, Jonelle Petscavage-Thomas, Rekha A Cherian, Adam Ulano, Sadhna B Nandwana, Nicole E Curci, Robert T Swanson, Rick Artrip, Tharakeswara K Bathala, Lori Mankowski Gettle, L Alexandre Frigini,

BACKGROUND:A Radiology Research Alliance Task Force was assembled in 2018 to review the literature on peer review and report on best practices for peer learning and peer coaching. FINDINGS:This report provides a historical perspective on peer review and the transition to peer collaborative learning and peer coaching. Most forms of ... Read more >>

Acad Radiol (Academic radiology)
[2020, 27(9):1261-1267]

Cited: 1 time

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Impact of preoperative prostate magnetic resonance imaging on the surgical management of high-risk prostate cancer.

Janet Baack Kukreja, Tharakeswara K Bathala, Chad A Reichard, Patricia Troncoso, Scott Delacroix, Benjamin Davies, Scott Eggener, Marc Smaldone, Mohummad Minhaj Siddiqui, Matthew Tollefson, Brian F Chapin,

<h4>Objective</h4>To evaluate the effect of adding multiparametric magnetic resonance imaging (mpMRI) to pre-surgical planning on surgical decision making for the management of high-risk prostate cancer (HRPC).<h4>Patients and methods</h4>A survey was designed to query multiple centers on surgical decisions of 41 consecutive HRPC cases seen from 2012 to 2015. HRPC was ... Read more >>

Prostate Cancer Prostatic Dis (Prostate cancer and prostatic diseases)
[2020, 23(1):172-178]

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Comparison of Abdominal Computed Tomographic Enhancement and Organ Lesion Depiction Between Weight-Based Scanner Software Contrast Dosing and a Fixed-Dose Protocol in a Tertiary Care Oncologic Center.

Corey T Jensen, Katherine J Blair, Nicolaus A Wagner-Bartak, Lan N Vu, Brett W Carter, Jia Sun, Tharakeswara K Bathala, Shiva Gupta,

<h4>Objective</h4>This study aimed to evaluate the quality of enhancement and solid-organ lesion depiction using weight-based intravenous (IV) contrast dosing calculated by injector software versus fixed IV contrast dose in oncologic abdominal computed tomographic (CT) examinations.<h4>Methods</h4>This institutional review board-exempt retrospective cohort study included 134 patients who underwent single-phase abdominal CT before ... Read more >>

J Comput Assist Tomogr (Journal of computer assisted tomography)
[2019, 43(1):155-162]

Cited: 1 time

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Acute Acalculous Cholecystitis in Hospitalized Patients With Hematologic Malignancies and Prognostic Importance of Gallbladder Ultrasound Findings.

Rajesh Thampy, Ahmad Khan, Islam H Zaki, Wei Wei, Brinda Rao Korivi, Greg Staerkel, Tharakeswara K Bathala,

OBJECTIVES:Patients with hematologic malignancies, especially those with acute disease or those receiving intense chemotherapy, are known to develop acute acalculous cholecystitis (AAC). The aim of this study was to evaluate the diagnostic and prognostic value of the established ultrasound (US) diagnostic criteria for AAC in patients with acute hematologic malignancies ... Read more >>

J Ultrasound Med (Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine)
[2019, 38(1):51-61]

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Pulse sequence considerations for simulation and postimplant dosimetry of prostate brachytherapy.

Jingfei Ma, Marinus A Moerland, Aradhana M Venkatesan, Tharakeswara K Bathala, Rajat J Kudchadker, Kristy K Brock, Steven J Frank,

<h4>Purpose</h4>The purpose of this work is to present a brief review of MRI physics principles pertinent to prostate brachytherapy, and a summary of our experience in optimizing protocols for prostate brachytherapy applications.<h4>Methods and materials</h4>We summarized essential MR imaging characteristics and their interplays that need to be considered for prostate brachytherapy ... Read more >>

Brachytherapy (Brachytherapy)
[2017, 16(4):743-753]

Cited: 4 times

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Radiogenomics of clear cell renal cell carcinoma: preliminary findings of The Cancer Genome Atlas-Renal Cell Carcinoma (TCGA-RCC) Imaging Research Group.

Atul B Shinagare, Raghu Vikram, Carl Jaffe, Oguz Akin, Justin Kirby, Erich Huang, John Freymann, Nisha I Sainani, Cheryl A Sadow, Tharakeswara K Bathala, Daniel L Rubin, Aytekin Oto, Matthew T Heller, Venkateswar R Surabhi, Venkat Katabathina, Stuart G Silverman,

<h4>Purpose</h4>To investigate associations between imaging features and mutational status of clear cell renal cell carcinoma (ccRCC).<h4>Materials and methods</h4>This multi-institutional, multi-reader study included 103 patients (77 men; median age 59 years, range 34-79) with ccRCC examined with CT in 81 patients, MRI in 19, and both CT and MRI in three; ... Read more >>

Abdom Imaging (Abdominal imaging)
[2015, 40(6):1684-1692]

Cited: 37 times

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Intraoperative sonography during open partial nephrectomy for renal cell cancer: does it alter surgical management?

Priya R Bhosale, Wei Wei, Randy D Ernst, Tharakeswara K Bathala, Rhoda M Reading, Christopher G Wood, Deepak G Bedi,

<h4>Objective</h4>The purpose of this study is to evaluate whether intraoperative ultrasound (IOUS) during open partial nephrectomy alters the surgical management for renal cell cancer (RCC).<h4>Materials and methods</h4>One hundred ninety-eight consecutive patients undergoing IOUS during open partial nephrectomy for RCC were selected for retrospective review of clinical and imaging data. Patient ... Read more >>

AJR Am J Roentgenol (AJR. American journal of roentgenology)
[2014, 203(4):822-827]

Cited: 9 times

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A rare presentation of lymphoma of the cervix with cross-sectional imaging correlation.

Brinda Rao Korivi, Corey T Jensen, Madhavi Patnana, Keyur P Patel, Tharakeswara K Bathala,

Non-Hodgkin's lymphoma of the cervix is an extremely uncommon entity, with no standard established treatment protocol. A 43-year-old asymptomatic female with a history of dual hit blastic B-cell lymphoma/leukemia in complete remission presented with an incidental cervical mass, which was initially felt to represent a cervical fibroid on computed tomography ... Read more >>

Case Rep Radiol (Case reports in radiology)
[2014, 2014:157268]

Cited: 3 times

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