Full Text Journal Articles by
Author Takashi Inoue

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Immunohistochemical study of dental pulp cells with 3D collagen type I gel in demineralized dentin tubules in vivo.

Sultan Zeb Khan, Sana Mirza, Samina Karim, Takashi Inoue, Mohammed S Bin-Shuwaish, Laila Al Deeb, Khold Al Ahdal, Rana S Al-Hamdan, Ahmed M Maawadh, Fahim Vohra, Tariq Abduljabbar,

Dental pulp cells (DPCs) represent good candidates for the regeneration of dental tissue. This study aimed to evaluate the growth and differentiation potential of DPCs cultured inside demineralized dentin tubules in vivo. Six green fluorescent protein-transgenic rats (body weight 100 g each) and thirty-two Sprague-Dawley (SD) male rats (body weight ... Read more >>

Bosn J Basic Med Sci (Bosnian journal of basic medical sciences)
[2020, 20(4):438-444]

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Functional benefits of corticosteroid and IVIG combination therapy in a coronary artery endothelial cell model of Kawasaki disease.

Takashi Inoue, Shokei Murakami, Kenji Matsumoto, Akio Matsuda,

BACKGROUND:Kawasaki disease (KD) is the most common pediatric systemic vasculitides of unknown etiology. Recent clinical studies led to reappraisal of the usefulness of initial combination therapy of intravenous immunoglobulin (IVIG) plus a corticosteroid for patients with severe KD. However, the molecular mechanisms underlying the clinical benefits of that combination therapy ... Read more >>

Pediatr Rheumatol Online J (Pediatric rheumatology online journal)
[2020, 18(1):76]

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Inflammatory Risk Factors for Early Recurrence of Non-Small Cell Lung Cancer Within One Year Following Curative Resection.

Satoru Kobayashi, Yoko Karube, Yuji Matsumura, Morimichi Nishihira, Takashi Inoue, Osamu Araki, Sumiko Maeda, Masayuki Chida,

BACKGROUND:Several inflammation-based scoring systems and nutritional indicators have been shown to have relevance to survival of patients with non-small cell lung cancer (NSCLC).The present study examined preoperative and pathological factors in patients who underwent curative resection for non-small cell lung cancer, with the aim to elucidate risk factors for early ... Read more >>

World J Surg (World journal of surgery)
[2020, 44(10):3510-3521]

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Color standardization and optimization in whole slide imaging.

Takashi Inoue, Yukako Yagi,

Whole slide imaging (WSI) has various uses, including the development of decision support systems, image analysis, education, conferences, and remote diagnostics. It is also used to develop artificial intelligence using machine learning methods. In the clinical setting, however, many issues have hindered the implementation of WSI. These issues are becoming ... Read more >>

Clin Diagn Pathol (Clinical and diagnostic pathology)
[2020, 4(1):]

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Clinical characteristics of 345 patients with coronavirus disease 2019 in Japan: A multicenter retrospective study.

Makoto Ishii, Hideki Terai, Hiroki Kabata, Katsunori Masaki, Shotaro Chubachi, Hiroki Tateno, Morio Nakamura, Kazumi Nishio, Hidefumi Koh, Risa Watanabe, Soichiro Ueda, Takeshi Terashima, Yusuke Suzuki, Kazuma Yagi, Naoki Miyao, Naoto Minematsu, Takashi Inoue, Ichiro Nakachi, Ho Namkoong, Satoshi Okamori, Shinnosuke Ikemura, Hirofumi Kamata, Hiroyuki Yasuda, Ichiro Kawada, Naoki Hasegawa, Koichi Fukunaga, ,

J. Infect. (The Journal of infection)
[2020, :]

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A non-human primate model of familial Alzheimer’s disease

Kenya Sato, Hiroki Sasaguri, Wakako Kumita, Takashi Inoue, Yoko Kurotaki, Kenichi Nagata, Naomi Mihira, Kaori Sato, Tetsushi Sakuma, Takashi Yamamoto, Michihira Tagami, Riichiroh Manabe, Kokoro Ozaki, Yasushi Okazaki, Takaomi Saido, Erika Sasaki,

Summary Alzheimer’s disease (AD) is a major cause of dementia, with the number of patients with this condition anticipated to exceed 50 million worldwide in the near future. Despite extensive research efforts, no effective measures are available to facilitate the prevention or treatment of AD, which is due in part ... Read more >>

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Detection and assessment of capsular invasion, vascular invasion and lymph node metastasis volume in thyroid carcinoma using microCT scanning of paraffin tissue blocks (3D whole block imaging): a proof of concept.

Bin Xu, Alexei Teplov, Kareem Ibrahim, Takashi Inoue, Ben Stueben, Nora Katabi, Meera Hameed, Yukako Yagi, Ronald Ghossein,

In the modern era, detailed pathologic characteristics of a thyroid tumor are crucial to achieve accurate diagnosis and guide treatment. The presence of capsular invasion (CI) is diagnostic for carcinoma, whereas vascular invasion (VI) and nodal metastasis (NM) are included in risk stratification. However, the very definition of CI and ... Read more >>

Mod. Pathol. (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2020, :]

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A detailed comparison between the endoscopic images using blue laser imaging and three-dimensional reconstructed pathological images of colonic lesions.

Takeshi Ueda, Kohei Morita, Fumikazu Koyama, Yuichi Teramura, Tadashi Nakagawa, Shinji Nakamura, Yayoi Matsumoto, Takashi Inoue, Takayuki Nakamoto, Yoshiyuki Sasaki, Hiroyuki Kuge, Maiko Takeda, Chiho Ohbayashi, Hisao Fujii, Masayuki Sho,

Blue laser/light imaging (BLI) is an image-enhanced endoscopy (IEE) technique that can provide an accurate diagnosis by closely observing the surface structure of various colonic lesions. However, complete correspondence between endoscopic images and pathological images has not been demonstrated. The aim of this study was to accurately compare endoscopic images ... Read more >>

PLoS One (PloS one)
[2020, 15(6):e0235279]

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A prospective study of oral 5-aminolevulinic acid to prevent adverse events in patients with localized prostate cancer undergoing low-dose-rate brachytherapy: Protocol of the AMBER study.

Makito Miyake, Nobumichi Tanaka, Isao Asakawa, Kaori Yamaki, Takashi Inoue, Shota Suzuki, Shunta Hori, Yasushi Nakai, Satoshi Anai, Kazumasa Torimoto, Michihiro Toritsuka, Hitoshi Nakagawa, Shinji Tsukamoto, Tomomi Fujii, Chiho Ohbayashi, Masatoshi Hasegawa, Masato Kasahara, Kiyohide Fujimoto,

Background:Radiotherapy is one of the most frequently selected treatment options for patients with prostate cancer. However, adverse effects related to the irradiated surrounding normal organs are significant clinical concerns. Specifically, genitourinary and gastrointestinal toxicities can lead to a dramatically reduced quality of life. The aim of this clinical trial is ... Read more >>

Contemp Clin Trials Commun (Contemporary clinical trials communications)
[2020, 19:100593]

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Intractable Hiccups as the Primary Symptom of a Perimedullary Arteriovenous Fistula at the Craniocervical Junction.

Keisuke Sasaki, Tomoo Inoue, Takashi Inoue, Yasuo Nishijima, Toshiki Endo, Masayuki Ezura, Hiroshi Uenohara, Kuniyasu Niizuma, Teiji Tominaga,

BACKGROUND:Hiccups are a well-known short-term phenomenon in daily life. If they persist or become intractable, they may be a primary symptom of a disease. Recent studies identified the medulla oblongata as the neuroanatomic center of the hiccup reflex arc. In previous cases, an isolated lesion at the dorsal side of ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 141:64-68]

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Functional benefits of corticosteroid and IVIG combination therapy in a coronary artery endothelial cell model of Kawasaki disease

Takashi Inoue, Shokei Murakami, Kenji Matsumoto, Akio Matsuda,

Abstract Background Kawasaki disease (KD) is the most common pediatric systemic vasculitides of unknown etiology. Recent clinical studies led to reappraisal of the usefulness of initial combination therapy of intravenous immunoglobulin (IVIG) plus a corticosteroid for patients with severe KD. However, the molecular mechanisms underlying the clinical benefits of that ... Read more >>

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Energy adjustment pulse shaping algorithm part II: realization of a spectral intensity design.

Koyo Watanabe, Takashi Inoue,

An accurately controlled arbitrary temporal waveform is required for many applications. To realize accurate pulse shaping, many optimization algorithms have been proposed to design spectral phase modulation patterns. However, as far as the authors know, no intensity optimization algorithm has been proposed. Therefore, in this paper, an algorithm is proposed ... Read more >>

Opt Express (Optics express)
[2020, 28(10):14815-14823]

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Management of Renal Arteries in Conjunction with Thoracic Endovascular Aortic Repair for Complicated Stanford Type B Aortic Dissection: The Japanese Multicenter Study (J-Predictive Study).

Shinichi Iwakoshi, Michael D Dake, Yoshihito Irie, Yoshiaki Katada, Shoji Sakaguchi, Norio Hongo, Katsuki Oji, Tetsuya Fukuda, Hitoshi Matsuda, Ryota Kawasaki, Takanori Taniguchi, Manabu Motoki, Makiyo Hagihara, Yoshihiko Kurimoto, Noriyasu Morikage, Hiroshi Nishimaki, Eijun Sueyoshi, Kyozo Inoue, Hideyuki Shimizu, Ichiro Ideta, Takatoshi Higashigawa, Osamu Ikeda, Naokazu Miyamoto, Motoki Nakai, Takahiro Nakai, Shigeo Ichihashi, Takeshi Inoue, Takashi Inoue, Masato Yamaguchi, Ryoichi Tanaka, Kimihiko Kichikawa,

Radiology (Radiology)
[2020, 295(2):E5]

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Energy adjustment pulse shaping algorithm part I: accuracy improvement of phase retrieval IFTA.

Koyo Watanabe, Takashi Inoue,

Techniques to generate a targeted temporal waveform with high accuracy are desirable to extend the application range for pulse shapers. In this study, a target energy adjustment mechanism is applied to the input-output iterative Fourier transform algorithm (IFTA). It is numerically demonstrated that, considering multi-pulse temporal waveforms, the developed algorithm ... Read more >>

Opt Express (Optics express)
[2020, 28(10):14807-14814]

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IL-1β and IL-17A are involved in IVIG resistance through activation of C/EBPβ and δ in a coronary artery model of Kawasaki disease.

Takashi Inoue, Masaki Miyashita, Shokei Murakami, Arisa Igarashi, Kenichiro Motomura, Jun Abe, Kenji Matsumoto, Akio Matsuda,

Allergy (Allergy)
[2020, 75(8):2102-2105]

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An improved de novo genome assembly of the common marmoset genome yields improved contiguity and increased mapping rates of sequence data.

Vasanthan Jayakumar, Hiromi Ishii, Misato Seki, Wakako Kumita, Takashi Inoue, Sumitaka Hase, Kengo Sato, Hideyuki Okano, Erika Sasaki, Yasubumi Sakakibara,

BACKGROUND:The common marmoset (Callithrix jacchus) is one of the most studied primate model organisms. However, the marmoset genomes available in the public databases are highly fragmented and filled with sequence gaps, hindering research advances related to marmoset genomics and transcriptomics. RESULTS:Here we utilize single-molecule, long-read sequence data to improve and ... Read more >>

BMC Genomics (BMC genomics)
[2020, 21(Suppl 3):243]

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Serum soluble interleukin-2 receptor level is a predictive marker for EBUS-TBNA-based diagnosis of sarcoidosis.

Jun Miyata, Takunori Ogawa, Yoichi Tagami, Takashi Sato, Mikie Nagayama, Toshiyuki Hirano, Naofumi Kameyama, Koichi Fukunaga, Akihiko Kawana, Takashi Inoue,

Background:Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a widely available diagnostic tool for suspected stage I/II sarcoidosis. Combination of EBUS-TBNA and transbronchial lung biopsy (TBLB) has been proposed as diagnostic procedure in clinical settings. Objectives:The aim of this study was to assess the diagnostic yield of combined EBUS-TBNA and TBLB ... Read more >>

Sarcoidosis Vasc Diffuse Lung Dis (Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG)
[2020, 37(1):8-16]

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Novel gastrointestinal disease in common marmosets characterised by duodenal dilation: a clinical and pathological study.

Takayuki Mineshige, Takashi Inoue, Masahiko Yasuda, Terumi Yurimoto, Kenji Kawai, Erika Sasaki,

Common marmosets (Callithrix jacchus) are frequently used for biomedical research but gastrointestinal diseases have been major health problems to maintain captive marmosets. We have diagnosed a novel gastrointestinal disease in marmosets, as which we propose to call 'marmoset duodenal dilation syndrome'; this disease is characterised by proximal duodenal obstruction and ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):3793]

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Anorectal Cancer in Crohn's Disease Has a Poor Prognosis Due to its Advanced Stage and Aggressive Histological Features: a Systematic Literature Review of Japanese Patients.

Takeshi Ueda, Takashi Inoue, Takayuki Nakamoto, Naoto Nishigori, Hiroyuki Kuge, Yoshiyuki Sasaki, Hisao Fujii, Fumikazu Koyama,

BACKGROUND:Patients with Crohn's disease (CD) are generally known to be at an increased risk of cancer. The anorectal area is the most frequent cancer site in Japanese CD patients. However, the risks are not well defined. The aim of this study was to clarify the clinicopathological characteristics of Japanese CD-associated ... Read more >>

J Gastrointest Cancer (Journal of gastrointestinal cancer)
[2020, 51(1):1-9]

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Usefulness of contrast-enhanced CT in the evaluation of depth of invasion in oral tongue squamous cell carcinoma: comparison with MRI.

Akira Baba, Hiroya Ojiri, Satoru Ogane, Kazuhiko Hashimoto, Takashi Inoue, Mutsumi Takagiwa, Tazuko K Goto,

OBJECTIVES:There is currently no standardized approach for assessing the depth of invasion (DOI) of oral tongue squamous cell carcinoma via diagnostic imaging. We investigated the usefulness of contrast-enhanced computed tomography (CECT) for estimating the pathological DOI of oral tongue squamous cell carcinoma by evaluating the correlation of pathological DOI with ... Read more >>

Oral Radiol (Oral radiology)
[2020, :]

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Effect of a Calcium-Enriched Lemon Beverage on Bone Metabolism and Bone Mineral Density in Postmenopausal Women: A Double-Blind, 11-Month, Intervention Study

Hiromi Ikeda, Tadayuki Iida, Masanori Hiramitsu, Takashi Inoue, Satomi Aoi, Miho Kanazashi, Fumiko Ishizaki, Toshihide Harada,

Abstract Background Key approaches to preventing the onset of osteoporosis are to maximize peak bone mass (PBM) in early adulthood and to minimize the inevitable loss of bone mineral density (BMD) after menopause. Consequently, osteoporosis attracts a great deal of social as well as medical attention in Japan, a country ... Read more >>

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Serum anti-recoverin antibodies is found in elderly patients with retinitis pigmentosa and cancer.

Taimu Sato, Koji M Nishiguchi, Kosuke Fujita, Fuyuki Miya, Takashi Inoue, Erika Sasaki, Toshifumi Asano, Satoru Tsuda, Yukihiro Shiga, Hiroshi Kunikata, Mitsuru Nakazawa, Toru Nakazawa,

PURPOSE:To screen for anti-recoverin antibodies in elderly patients with retinitis pigmentosa (RP) with or without cancer and cross-sectionally characterize the seropositive patients clinically. METHODS:Serum from 75 RP patients who had been tested for mutations in a panel of 83 RP genes and 73 normal controls, all aged 50-80 years, were screened ... Read more >>

Acta Ophthalmol (Acta ophthalmologica)
[2020, 98(6):e722-e729]

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Measurement of baseline locomotion and other behavioral traits in a common marmoset model of Parkinson's disease established by a single administration regimen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: providing reference data for efficacious preclinical evaluations.

Kiyoshi Ando, Takashi Inoue, Keigo Hikishima, Yuji Komaki, Kenji Kawai, Ryo Inoue, Chiyoko Nishime, Eiko Nishinaka, Koji Urano, Hideyuki Okano,

Baseline locomotion and behavioral traits in the common marmoset Parkinson's disease model were examined to provide basic information for preclinical evaluations of medical treatments. A single regimen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine at a cumulative dose of 5 mg/kg as the free base over three consecutive days was administered subcutaneously to 10 marmosets. ... Read more >>

Behav Pharmacol (Behavioural pharmacology)
[2020, 31(1):45-60]

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Optimal Timing of Extracranial-Intracranial Bypass with Microsurgical Trapping for Ruptured Blister Aneurysms of the Internal Carotid Artery.

Hidenori Endo, Miki Fujimura, Hiroaki Shimizu, Toshiki Endo, Shunsuke Omodaka, Takashi Inoue, Kenichi Sato, Kuniyasu Niizuma, Teiji Tominaga,

OBJECTIVE:Ruptured blister aneurysms of the internal carotid artery are challenging to treat because of their difficult diagnosis and the fragility of the wall structure. Here, we sought to clarify the efficacy of extracranial-intracranial bypass followed by trapping (bypass/trapping) for ruptured blister aneurysms. METHODS:A retrospective study identified 45 patients with ruptured ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 136:e567-e577]

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Thoracic Dural Arteriovenous Fistula Presenting with Isolated Pseudobulbar Palsy Mimicking Brainstem Lesion.

Keisuke Sasaki, Tomoo Inoue, Yasuo Nishijima, Takashi Inoue, Shinsuke Suzuki, Toshiki Endo, Masayuki Ezura, Hiroshi Uenohara, Teiji Tominaga,

BACKGROUND:Spinal dural arteriovenous fistulas (DAVFs) are usually associated with neurologic dysfunction adjacent to the shunt point; however, the symptoms are uncommon far from the site of the fistula. To our knowledge, this is the first report of a patient with rapidly progressive isolated pseudobulbar palsy because of thoracic DAVF. CASE ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 136:157-160]

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