Full Text Journal Articles by
Author Syed Muhammad Ali Shah

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Therapeutic Efficacy of Urinile Against Gouty Arthritis.

Saeed Ahmad, Ejaz Mohiuddin, Syed Muhammad Ali Shah, Muhammad Akram, Muhammad Amjad, Jaweria Nisar, Muhammad Riaz, Naveed Munir, Ghulam Rasool,

Gout is arthritis caused due to Monosodium urate (MSU) crystals deposition occurring particularly in patients with associated comorbidities limiting the use of conventional therapies. This study was planned to evaluate the therapeutic efficacy of urinile (a herbal drug) for the treatment of gouty arthritis. Allopurinol was used as standard drug ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2020, 18(4):1559325820946934]

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Hantavirus diseases pathophysiology, their diagnostic strategies and therapeutic approaches: A review.

Naveed Munir, Muhammad Jahangeer, Shoukat Hussain, Zahed Mahmood, Mehvish Ashiq, Fatima Ehsan, Muhammad Akram, Syed Muhammad Ali Shah, Muhammad Riaz, Aneezah Sana,

Hantaviruses are enveloped negative (-) single-stranded RNA viruses belongs to Hantaviridae family, hosted by small rodents and entering into the human body through inhalation, causing haemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) also known as hantavirus cardiopulmonary syndrome (HCPS). Hantaviruses infect approximately more than 200 000 people ... Read more >>

Clin Exp Pharmacol Physiol (Clinical and experimental pharmacology & physiology)
[2020, :]

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Antihypertensive and Antihyperlipidemic Activity of Aqueous Methanolic Extract of Rauwolfia Serpentina in Albino Rats.

Syed Muhammad Ali Shah, Syed Ali Raza Naqvi, Naveed Munir, Sohaib Zafar, Muhammad Akram, Jaweria Nisar,

Rauwolfia serpentina has a wide range of therapeutic effects so this study was planned to explore the antihypertensive and antihyperlipidemic therapeutic responses of R serpentina doses using albino rats by measuring the blood pressure, biochemical parameters, and histological architecture of liver and kidney tissues. Thirty albino rats were divided into ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2020, 18(3):1559325820942077]

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A Novel Strategy Facilitates Reference Gene Selection by RT-qPCR Analysis in Kidney Yang Deficiency Syndrome Mice Infected with the Influenza A (H1N1) Virus.

Yepei Fu, Jia Yang, Shanshan Fan, Shaozhe Zhao, Syed Muhammad Ali Shah, Muhammad Akram, Rong Rong, Yong Yang,

In reverse transcription-quantitative polymerase chain reaction (RT-qPCR) studies, endogenous reference genes are routinely used to normalize the expression of target gene studies. In order to precisely evaluate the relative expression of genes in the cells of mice suffering from Kidney Yang Deficiency Syndrome (KYDS) in response to influenza A virus ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:9075165]

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Progress and prospects in the management of bacterial infections and developments in Phytotherapeutic modalities.

Muhammad Akram, Muhammad Riaz, Naveed Munir, Akhtar Rasul, Muhammad Daniyal, Muhammad Daniyal, Syed Muhammad Ali Shah, Mohammad Ali Shariati, Ghazala Shaheen, Naheed Akhtar, Farzana Parveen, Naheed Akhter, Aymen Owais Ghauri, Abdul Wadood Chishti, Muhammad Usman Sarwar, Fahad Said Khan,

The advent of antibiotics revolutionized medical care resulting in significantly reduced mortality and morbidity caused by infectious diseases. However, excessive use of antibiotics has led to the development of antibiotic resistance and indeed, the incidence of multidrug-resistant pathogens is considered as a major disadvantage in medication strategy, which has led ... Read more >>

Clin Exp Pharmacol Physiol (Clinical and experimental pharmacology & physiology)
[2020, 47(7):1107-1119]

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Antimicrobial and Antihypercholesterolemic Activities of Pulicaria gnaphalodes.

Syed Ali Raza Naqvi, Syed Muhammad Ali Shah, Laiba Kanwal, Muhammad Saeed, Atta-Ul-Haq, Jaweria Nisar, Zonaira Nisar, Muhammad Akram,

Multidrug resistance has increased globally in the communities. Bacterial infections associated with health care have weakened the existing antimicrobial therapy and demand the search for alternative therapies. In the present investigation, the medicinal plant Pulicaria gnaphalodes from Quetta, Pakistan, has been screened for antimicrobial potential. In vitro antimicrobial efficacy of ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2020, 18(1):1559325820904858]

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Naegleria fowleri: Sources of infection, pathophysiology, diagnosis, and management; a review.

Muhammad Jahangeer, Zahed Mahmood, Naveed Munir, Umm-E-Amara Waraich, Imtiaz Mahmood Tahir, Muhammad Akram, Syed Muhammad Ali Shah, Syed Muhammad Ali Shah, Ayesha Zulfqar, Rida Zainab,

Naegleria fowleri, a thermophilic flagellate amoeba known as a "brain-eating" amoeba, is the aetiological agent of a perilous and devastating waterborne disease known as primary amoebic meningoencephalitis (PAM), both in humans as well as in animals. PAM is a rare but fatal disease affecting young adults all around the world, ... Read more >>

Clin. Exp. Pharmacol. Physiol. (Clinical and experimental pharmacology & physiology)
[2020, 47(2):199-212]

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Ex-vivo antihypertensive and calcium channel blocking activity of Androsace foliosa n-hexane leaves fraction on isolated rabbit aorta.

Jawad Zaheer, Abida Kausar, Hina Kanwal, Noreen Akhtar, Aisha Ilyas, Zil-I-Huma Nazlli, Ayesha Riaz, Syed Muhammad Ali Shah, Muhammad Akram, Muhammad Usman Sarwar, Abdul Hamid Khan, Fahad Said Khan, Farhan Asad, Hina Anwar, Madeeha Anwar,

Hypertension is persistent elevation in blood pressure for 3-4 weeks. Estimated global prevalence of hypertension suggested that by the Year 2025 (29%) of adult worldwide are suffering from hypertension (1.56 billion). Hypertension complications are hemorrhage, atherosclerosis, renal artery stenosis, angina pectoris end organ damage, cardiomyopathy, myocardial infarction and retinopathy. Along ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(6(Supplementary)):2893-2898]

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Assessment of Cucumber Genotypes for Salt Tolerance Based on Germination and Physiological Indices.

Asma Marium, Abida Kausar, Syed Muhammad Ali Shah, Syed Muhammad Ali Shah, Muhammad Yasin Ashraf, Noreen Akhtar, Muhammad Akram, Muhammad Riaz,

Soil salinity is one of the primary problem for agricultural crops which causes a great loss in crop production in Pakistan and worldwide. Various approaches have been implemented to overcome salinity problem. Assembly of crops for the enhancement of salt tolerance is a good strategy to achieve cost-effective yields. Cucumber ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2019, 17(4):1559325819889809]

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Ex-vivo abortifacient activity of Androsace foliosa n-hexane leaves extract on isolated rabbit uterus.

Jawad Zaheer, Qazi Najam-Us-Saqib, Asif Mehmmod Hashmi, Muhammad Mukhtiar, Sadia Zafar, Muhammad Riaz, Ghulam Rasool, Muhammad Akram, Syed Muhammad-Ali Shah, Saher Rahat, Faid Said Khan,

Androsace foliosa is a medicinal herb utilized in different areas of Pakistan for abortifacient, diabetic and liver complications. In the current research, the possible action of the n-hexane leaves extract of the Androsace foliosa on isolated rabbit uterus was examined. Abortifacient activity was examined in the existence of standard antagonist ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(5(Supplementary)):2333-2339]

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Correlates of diabetic retinopathy: A case study.

Muhammad Aftab, Alina Ramzan, Sajjad Haider Bhatti, Tanvir Ahmad, Muhammad Ali Raza, Syed Muhammad Ali Shah, Muhammad Akram,

Prevalence of diabetes mellitus is increasing worldwide particularly in developing countries as according to International Diabetes Federation, globally a rise from 451 million diabetic people in 2017 to 693 million in 2045 is expected. Diabetic retinopathy is one of the major consequences of diabetes mellitus, so knowing its risk factors ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(4(Supplementary)):1909-1912]

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Hexose monophosphate shunt, the role of its metabolites and associated disorders: A review.

Muhammad Akram, Syed Muhammad Ali Shah, Naveed Munir, Muhammad Daniyal, Imtiaz Mahmood Tahir, Zahed Mahmood, Muhammad Irshad, Muhammad Akhlaq, Sabira Sultana, Rida Zainab,

The hexose monophosphate (HMP) shunt acts as an essential component of cellular metabolism in maintaining carbon homeostasis. The HMP shunt comprises two phases viz. oxidative and nonoxidative, which provide different intermediates for the synthesis of biomolecules like nucleotides, DNA, RNA, amino acids, and so forth; reducing molecules for anabolism and detoxifying the reactive oxygen species ... Read more >>

J. Cell. Physiol. (Journal of cellular physiology)
[2019, :]

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Therapeutic potential of medicinal plants for the management of urinary tract infection: A systematic review.

Ghazala Shaheen, Muhammad Akram, Farhat Jabeen, Syed Muhammad Ali Shah, Naveed Munir, Muhammad Daniyal, Muhammad Riaz, Imtiaz Mahmood Tahir, Aymen Owais Ghauri, Sabira Sultana, Rida Zainab, Muslim Khan,

Urinary tract infection (UTI) is one of the most severe public health problem affecting both sexes but females are more susceptible due to the differences in urogenital and reproductive anatomy, physiology and lifestyle. As in UTI, different parts of the urinary tract are affected and morbidity due to UTI is ... Read more >>

Clin Exp Pharmacol Physiol (Clinical and experimental pharmacology & physiology)
[2019, 46(7):613-624]

Cited: 1 time

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Cardioprotective Potential of Plant-Derived Molecules: A Scientific and Medicinal Approach.

Syed Muhammad Ali Shah, Muhammad Akram, Muhammad Riaz, Naveed Munir, Ghulam Rasool,

Since the beginning of human civilization, plants have been used in alleviating the human distress and it was recorded for about thousands of years ago that the plants are being used for medicinal purposes. Natural bioactive compounds called phytochemicals are obtained from medicinal plants, vegetables, and fruits, which functions to ... Read more >>

(Dose-response : a publication of International Hormesis Society)
[2019, 17(2):1559325819852243]

Cited: 3 times

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Progress and prospects in the management of psoriasis and developments in phyto-therapeutic modalities.

Muhammad Daniyal, Muhammad Akram, Rida Zainab, Naveed Munir, Syed Muhammad Ali Shah, Bin Liu, Wei Wang, Muhammad Riaz, Farhat Jabeen,

The aim of this study is to review the efficacy of herbal and allopathic drugs used to manage and treat psoriasis. The review has been compiled using reference materials from major databases, Online Journals, Science Direct, Scopus, Open J Gate, Google Scholar and PubMed. Psoriasis is a common skin disease ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2019, 32(3):e12866]

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Phytochemical screening and antipyretic effects of hydroalcoholic extracts of selected medicinal plants of Rawalakot, Azad Jammu and Kashmir in albino rats.

Mahvish Ajaz, Muhammad Akram, Hafiz Muhammad Asif, Abid Hussain, Syed Muhammad Ali Shah, Imtiaz Mahmood Tahir, Muhammad Daniyal, Fahad Said Khan,

Pyrexia occurs due to infection, malignancy and other diseases. Majority of the antipyretic drugs are synthetic in nature which exerts side effects such as gastric ulcer, hepatic necrosis and renal damage. The antipyretic potential of the hydro-alcoholic extracts of Achillea millefolium, Taraxacum officinale, Salix alba and Trigonella foenum were investigated ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(2):581-592]

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Determination of oil contents from eight varieties of olea europaea (Olive) grown in Pakistan.

Abdul Khaliq, Syed Muhammad Ali Shah, Muhammad Akram, Naveed Munir, Muhammad Daniyal, Muhammad Irshad, Saeed Ahmad,

The olive (Olea europaea L.) is a worldwide famous tree crop having valuable commercial role due to nutritional as well as therapeutic benefits obtained from its edible oil. Eight varieties of Olea europaea L. fruits were obtained from three Agricultural research institutes located in different areas of Pakistan including Quetta, ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, 34(13):1951-1955]

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Daclatasvir plus Sofosbuvir with or without ribavirin in patients with chronic Hepatitis C genotype 3a in Pakistani population - A real world experience.

Zamir Butt, Syed Muhammad Ali Shah,

Background and Objectives:Pakistan is among leading countries of world in prevalence of chronic hepatitis C Daclatasvir plus sofosbuvir is recommended for treatment of CHC. The purpose of study was to determine the sustained virological response in patients with chronic viral hepatitis C genotype 3a irrespective of previous treatment experience or ... Read more >>

(Pakistan journal of medical sciences)
[2019, 35(2):409-413]

Cited: 1 time

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Phytochemical analysis and hepatoprotective effect of polyherbal formulation on CCl4 induced hepatotoxicity in mice.

Fahad Said Khan, Muhammad Akram, Nosheen Aslam, Jawad Zaheer, Sodah Bint Mustafa, Shamaila Kausar, Abdul Hamid Khan, Iftikhar Ahmad Khan, Naveed Munir, Syed Muhammad Ali Shah, Imtiaz Mahmood Tahir, Aamir Sharif,

The potent phytotherapeutic modalities against the hepatotoxicity have motivated us to explore numerous plants and polyherbal preparations because conventional drug discovery is more expensive and tedious. So, this study was conducted to evaluate the hepatoprotective potential of a polyherbal formulation (PHF), comprising of Solanum nigrum, Silybum marianum, Atrmesia absinthium, Achillea ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(6 (Supplementary):2719-2723]

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Prevalence and current therapy in chronic liver disorders.

Muhammad Daniyal, Muhammad Akram, Rida Zainab, Naveed Munir, Aamir Sharif, Syed Muhammad Ali Shah, Bin Liu, Wei Wang,

BACKGROUND:Herbal medicine plays an important role in health, particularly in remote parts of developing areas with few health facilities. According to WHO estimates, about three-quarters of the world's population currently use herbs or traditional medicines to treat various ailments, including liver diseases. Several studies have found that the use of ... Read more >>

Inflammopharmacology (Inflammopharmacology)
[2019, 27(2):213-231]

Cited: 1 time

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Acute and sub acute toxicity study and randomized clinical trial of polyherbal coded drug candicure in the management of acute vulvo-vaginal candidiasis.

Sabira Sultana, Tasneem Qureshi, Hafiz Muhammad Asif, Muhammad Akram, Sultan Ayaz, Syed Muhammad Ali Shah,

Vulvo-Vaginal Candidiasis is common gynecological disorder. Clinical trials are designed to evaluate the effect of medical intervention with allopathic and herbal medicine to treat vulvo-vaginal candidiasis. The toxicity index and the safety profile of test drug were assessed on animals' model. Toxicity study of polyherbal formulation was done in order ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(1(Supplementary)):315-322]

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Prevalence and co-infection of Malaria and Typhoid in the local population of Faisalabad, Pakistan.

Hasan Abdaal Jalani, Syed Muhammad Ali Shah, Fozia Anjum, Samreen Gul Khan, Naheed Akhter, Muslim Khan, Muhammad Akram, Imtiaz Mahmood Tahir, Naveed Munir,

Malaria and typhoid fever are among the major infectious diseases which impose significant health and socioeconomic burden on affected populations. Further, co-infection and resembling symptomatology in both infections, mostly leads to misdiagnosis and mistreatment. So co-infection of malaria and typhoid fever is becoming a major issue in tropical and subtropical ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(1(Supplementary)):323-326]

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The evaluation ofefficacy and safety of Cough (EMA) granules used for upper respiratory disorders.

Muhammad Faizan Khan, Muhammad Akram, Naheed Akhter, Muhammad Mukhtiar, Rabia Zahid, Fahad Said Khan, Muhammad Daniyal, Imtiaz Mahmood Tahir, Khalil Ahmed, Aamir Sharif, Shamaila Kausar, Syed Muhammad Ali Shah, Khan Usmanghani,

Ivy leaf is used for the treatment of respiratory diseases with the intensive mucus formation, respiratory infections, and irritating cough coming from the common cold. Conferring to clinical trials, the efficacy, and tolerability of ivy leaf is good. The main compounds accountable for biological activity are triterpene and saponins. Ivy ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(6 (Supplementary):2617-2622]

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Effects of methanolic and aqueous extracts of Ipomoea batatas L on mineral contents level (calcium and magnesium) in alloxan-induced diabetic rats.

Imtiaz Mahmood Tahir, Naheed Akhter, Abida Parveen, Huma Mehboob, Sadaf Saleem, Naveed Munir, Syed Muhammad-Ali Shah, Jawad Zaheer, Fahad Said Khan, Sabira Sultana, Muhammad Akram,

In diabetic patients, electrolyte disorders frequently occur with the characteristic changes in minerals like calcium and magnesium etc. Several medicines are used to manage diabetes mellitus but they exert adverse effects. Plants are a valuable alternative to synthetic medicines because they are easily available, economical and have fewer side effects. ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(5(Supplementary)):2077-2083]

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Anti-diabetic activity of aqueous extract of Ipomoea batatas L. in alloxan induced diabetic Wistar rats and its effects on biochemical parameters in diabetic rats.

Shagufta Kamal, Naheed Akhter, Samreen Gul Khan, Shumaila Kiran, Tahir Farooq, Muhammad Akram, Syed Muhammad Ali Shah, Imtiaz Mahmood Tahir, Muhammad Akhlaq, Fahad Said, Jawad Zaheer,

Diabetes is a condition where the fasting blood glucose level elevated above the normal range (80-120mg/dL). This increase in blood glucose level may be due to the insulin deficiency i.e. insulin dependent diabetes mellitus (IDDM or type I) or due to insulin resistance i.e. non-insulin dependent diabetes mellitus (NIDDM or ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(4(Supplementary)):1539-1548]

Cited: 1 time

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