Full Text Journal Articles by
Author Suteeraporn Pinyakorn

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Brief Report: Syphilis Incidence and Effect on Viral Load, CD4, and CD4/CD8 Ratio in a Thai Cohort of Predominantly Men Who Have Sex With Men Living With HIV.

Camilla Muccini, Trevor A Crowell, Suteeraporn Pinyakorn, Eugène Kroon, Carlo Sacdalan, Jintanat Ananworanich, Sandhya Vasan, Nittaya Phanuphak, Donn J Colby, ,

<h4>Background</h4>Syphilis has been increasing in the past years, especially among men who have sex with men (MSM). The aim of the study was to assess syphilis prevalence and incidence and changes in CD4 count and viremia in the RV254 cohort of persons living with HIV who initiated antiretroviral therapy during ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, 86(2):219-223]

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Longitudinal Analysis of Peripheral and Colonic CD161+ CD4+ T Cell Dysfunction in Acute HIV-1 Infection and Effects of Early Treatment Initiation.

Kerri G Lal, Yuwadee Phuang-Ngern, Suchada Suhkumvittaya, Edwin Leeansyah, Aljawharah Alrubayyi, Joana Dias, Adam Waickman, Dohoon Kim, Eugène Kroon, Suteeraporn Pinyakorn, Leigh Anne Eller, Milton Maciel, Rungsun Rerknimitr, Nitiya Chomchey, Nittaya Phanuphak, Mark S S de Souza, Sorachai Nitayaphan, Julie A Ake, Sandhya Vasan, Merlin L Robb, Jintanat Ananworanich, Johan K Sandberg, Alexandra Schuetz, Michael A Eller, Dominic Paquin-Proulx,

CD161 expression on CD4<sup>+</sup> T cells is associated with a Th17 functional phenotype, as well as with an innate capacity to respond to interleukin (IL)-12 and IL-18 without T cell receptor (TCR) stimulation. Chronic HIV-1 infection is associated with loss of the CD161<sup>+</sup> CD4 T cell population, and non-human primate ... Read more >>

Viruses (Viruses)
[2020, 12(12):]

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Minimal detection of cerebrospinal fluid escape after initiation of antiretroviral therapy in acute HIV-1 infection.

Ryan Handoko, Phillip Chan, Linda Jagodzinski, Suteeraporn Pinyakorn, Sasiwimol Ubolyam, Nittaya Phanuphak, Carlo Sacdalan, Eugene Kroon, Netsiri Dumrongpisutikul, Robert Paul, Victor Valcour, Jintanat Ananworanich, Sandhya Vasan, Serena Spudich, ,

<h4>Objective</h4>Despite suppression of HIV-1 replication in the periphery by antiretroviral therapy (ART), up to 10% of treated individuals have quantifiable HIV-1 in the CSF, termed CSF escape. CSF escape may be asymptomatic but has also been linked to progressive neurological disease, and may indicate persistence of HIV in the central ... Read more >>

AIDS (AIDS (London, England))
[2020, :]

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Inflammatory Biomarkers Do Not Differ Between Persistently Seronegative vs Seropositive People With HIV After Treatment in Early Acute HIV Infection.

Catherine W Cai, Suteeraporn Pinyakorn, Eugène Kroon, Mark de Souza, Donn J Colby, Tippawan Pankam, Supanit Pattanachaiwit, Sasiwimol Ubolyam, Adam Rupert, Perrine Lallemand, Robin Dewar, Helene C Highbarger, Jintanat Ananworanich, Sandhya Vasan, Irini Sereti,

Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dimer, soluble cluster of differentiation 14, C-reactive protein, and interleukin-6, indicating that seronegativity does not affect chronic ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(9):ofaa383]

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Corrigendum to: Impact of Acute HIV Infection and Early Antiretroviral Therapy on the Human Gut Microbiome.

Ornella Sortino, Nittaya Phanuphak, Alexandra Schuetz, Alexandra M Ortiz, Nitiya Chomchey, Yasmine Belkaid, Jacquice Davis, Harry A Mystakelis, Mariam Quiñones, Claire Deleage, Brian Ingram, Rungsun Rerknimitr, Suteeraporn Pinyakorn, Adam Rupert, Merlin L Robb, Jintanat Ananworanich, Jason Brenchley, Irini Sereti,

[This corrects the article DOI: 10.1093/ofid/ofz367.]. ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(9):ofaa381]

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Brief Report: Group Sex and Methamphetamine Use Fuel an Explosive Epidemic of Hepatitis C Among HIV-Infected Men Who Have Sex With Men in Bangkok, Thailand.

Tanyaporn Wansom, Suteeraporn Pinyakorn, Christy J Kolsteeg, Eugene Kroon, Carlo P Sacdalan, Nitiya Chomchey, Jintanat Ananworanich, Sandhya Vasan, Nittaya Phanuphak, Donn J Colby,

BACKGROUND:Increased rates of hepatitis C virus (HCV) infection among HIV-infected men who have sex with men (MSM) and who deny injecting drugs have been reported in resource-rich settings. SETTING:We measured HCV prevalence and incidence in a predominantly MSM cohort with acute HIV infection in Bangkok, Thailand. METHODS:In 2009-2018, participants with ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2020, 84(4):331-335]

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Inflammatory Biomarkers Do Not Differ Between Persistently Seronegative vs Seropositive People With HIV After Treatment in Early Acute HIV Infection

Catherine W Cai, Suteeraporn Pinyakorn, Eugène Kroon, Mark de Souza, Donn J Colby, Tippawan Pankam, Supanit Pattanachaiwit, Sasiwimol Ubolyam, Adam Rupert, Perrine Lallemand, Robin Dewar, Helene C Highbarger, Jintanat Ananworanich, Sandhya Vasan, Irini Sereti,

Abstract Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dimer, soluble cluster of differentiation 14, C-reactive protein, and interleukin-6, indicating that seronegativity does not affect ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(9):]

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A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection.

Eugène D M B Kroon, Jintanat Ananworanich, Amélie Pagliuzza, Ajantha Rhodes, Nittaya Phanuphak, Lydie Trautmann, Julie L Mitchell, Michelle Chintanaphol, Jintana Intasan, Suteeraporn Pinyakorn, Khuntalee Benjapornpong, J Judy Chang, Donn J Colby, Nitiya Chomchey, James L K Fletcher, Keith Eubanks, Hua Yang, John Kapson, Ashanti Dantanarayana, Surekha Tennakoon, Robert J Gorelick, Frank Maldarelli, Merlin L Robb, Jerome H Kim, Serena Spudich, Nicolas Chomont, Praphan Phanuphak, Sharon R Lewin, Mark S de Souza, ,

<h4>Objective and design</h4>A randomized, open-label pilot study in individuals treated with antiretroviral therapy (ART) since acute HIV infection (AHI) with a regimen including a histone deacetylase inhibitor to induce HIV from latency and control HIV replication during subsequent treatment interruption (TI).<h4>Methods</h4>Fifteen participants who initiated ART at AHI were randomized to ... Read more >>

J Virus Erad (Journal of virus eradication)
[2020, 6(3):100004]

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Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound.

Evan M Cale, Hongjun Bai, Meera Bose, Michael A Messina, Donn J Colby, Eric Sanders-Buell, Bethany Dearlove, Yifan Li, Emily Engeman, Daniel Silas, Anne Marie O'Sullivan, Brendan Mann, Suteeraporn Pinyakorn, Jintana Intasan, Khunthalee Benjapornpong, Carlo Sacdalan, Eugène Kroon, Nittaya Phanuphak, Robert Gramzinski, Sandhya Vasan, Merlin L Robb, Nelson L Michael, Rebecca M Lynch, Robert T Bailer, Amélie Pagliuzza, Nicolas Chomont, Amarendra Pegu, Nicole A Doria-Rose, Lydie Trautmann, Trevor A Crowell, John R Mascola, Jintanat Ananworanich, Sodsai Tovanabutra, Morgane Rolland, ,

Infusion of the broadly neutralizing antibody VRC01 has been evaluated in individuals chronically infected with HIV-1. Here, we studied how VRC01 infusions affected viral rebound after cessation of antiretroviral therapy (ART) in 18 acutely treated and durably suppressed individuals. Viral rebound occurred in all individuals, yet VRC01 infusions modestly delayed ... Read more >>

J Clin Invest (The Journal of clinical investigation)
[2020, 130(6):3299-3304]

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Plasmacytoid dendritic cells sense HIV replication before detectable viremia following treatment interruption.

Julie L Mitchell, Hiroshi Takata, Roshell Muir, Donn J Colby, Eugène Kroon, Trevor A Crowell, Carlo Sacdalan, Suteeraporn Pinyakorn, Suwanna Puttamaswin, Khunthalee Benjapornpong, Rapee Trichavaroj, Randall L Tressler, Lawrence Fox, Victoria R Polonis, Diane L Bolton, Frank Maldarelli, Sharon R Lewin, Elias K Haddad, Praphan Phanuphak, Merlin L Robb, Nelson L Michael, Mark de Souza, Nittaya Phanuphak, Jintanat Ananworanich, Lydie Trautmann, ,

Plasmacytoid dendritic cells (pDCs) are robust producers of IFNα and one of the first immune cells to respond to SIV infection. To elucidate responses to early HIV-1 replication, we studied blood pDCs in 29 HIV-infected participants who initiated antiretroviral therapy during acute infection and underwent analytic treatment interruption (ATI). We ... Read more >>

J Clin Invest (The Journal of clinical investigation)
[2020, 130(6):2845-2858]

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Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption.

Donn J Colby, Michal Sarnecki, Dan H Barouch, Somporn Tipsuk, Daniel J Stieh, Eugène Kroon, Alexandra Schuetz, Jintana Intasan, Carlo Sacdalan, Suteeraporn Pinyakorn, Pornsuk Grandin, Hongshuo Song, Sodsai Tovanabutra, Zhanna Shubin, Dohoon Kim, Dominic Paquin-Proulx, Michael A Eller, Rasmi Thomas, Mark de Souza, Lindsay Wieczorek, Victoria R Polonis, Amélie Pagliuzza, Nicolas Chomont, Lauren Peter, Joseph P Nkolola, Johan Vingerhoets, Carla Truyers, Maria G Pau, Hanneke Schuitemaker, Nittaya Phanuphak, Nelson Michael, Merlin L Robb, Frank L Tomaka, Jintanat Ananworanich,

We administered Ad26, modified vaccinia Ankara vectors containing mosaic HIV-1 antigens or placebo in 26 individuals who initiated antiretroviral therapy during acute human immunodeficiency virus infection as an exploratory study to determine the safety and duration of viremic control after treatment interruption. The vaccine was safe and generated robust immune ... Read more >>

Nat Med (Nature medicine)
[2020, 26(4):498-501]

Cited: 1 time

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Feasibility and safety of research sigmoid colon biopsy in a cohort of Thai men who have sex with men with acute HIV-1.

Michelle Chintanaphol, Carlo Sacdalan, Suteeraporn Pinyakorn, Rungsun Rerknimitr, Wiriyaporn Ridtitid, Piyapan Prueksapanich, Irini Sereti, Alexandra Schuetz, Trevor A Crowell, Donn J Colby, Merlin L Robb, Nittaya Phanuphak, Jintanat Ananworanich, Serena S Spudich, Eugène Kroon,

Background:The gut-associated lymphoid tissue (GALT) is a major reservoir of HIV-1 established early in acute HIV-1 infection (AHI). Sampling tissue from GALT can provide information about viral reservoirs and immune responses but may be complicated during AHI for reasons such as high viral replication, CD4 T cell depletion and immune ... Read more >>

J Virus Erad (Journal of virus eradication)
[2020, 6(1):7-10]

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Neuropsychiatric outcomes before and after switching to dolutegravir-based therapy in an acute HIV cohort.

Phillip Chan, Orlanda Goh, Eugène Kroon, Donn Colby, Carlo Sacdalan, Suteeraporn Pinyakorn, Peeriya Prueksakaew, Peter Reiss, Jintanat Ananworanich, Victor Valcour, Serena Spudich, Robert Paul, ,

<h4>Introduction</h4>Dolutegravir (DTG)-based antiretroviral therapy (ART) is currently the first-line treatment for people living with HIV. Neuropsychiatric adverse events (NP-AEs) have been reported with DTG but neuropsychiatric symptoms have not been systemically quantified using structured scales. This study examined mood and cognitive parameters before and after a planned transition from non-DTG ... Read more >>

AIDS Res Ther (AIDS research and therapy)
[2020, 17(1):1]

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Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection.

Michael J Peluso, Donn J Colby, Suteeraporn Pinyakorn, Sasiwimol Ubolyam, Jintana Intasan, Rapee Trichavaroj, Nitiya Chomchey, Peeriya Prueksakaew, Bonnie M Slike, Shelly J Krebs, Ningbo Jian, Merlin L Robb, Praphan Phanuphak, Nittaya Phanuphak, Serena Spudich, Jintanat Ananworanich, Eugène Kroon, ,

<h4>Introduction</h4>Liver disease is a common cause of non-AIDS morbidity and mortality in people living with HIV (PLHIV), but the prevalence and significance of liver function test (LFT) abnormalities in early HIV infection is unknown. This study aimed to characterize LFTs in a large cohort of participants with acute HIV infection ... Read more >>

J Int AIDS Soc (Journal of the International AIDS Society)
[2020, 23(1):e25444]

Cited: 1 time

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Impact of Acute HIV Infection and Early Antiretroviral Therapy on the Human Gut Microbiome.

Ornella Sortino, Nittaya Phanuphak, Alexandra Schuetz, Alexandra M Ortiz, Nitiya Chomchey, Yasmine Belkaid, Jacquice Davis, Harry A Mystakelis, Mariam Quiñones, Claire Deleage, Brian Ingram, Rungsun Rerknimitr, Suteeraporn Pinyakorn, Adam Rupert, Merlin L Robb, Jintanat Ananworanich, Jason Brenchley, Irini Sereti, ,

<h4>Background</h4>Intestinal microbial dysbiosis is evident in chronic HIV-infected individuals and may underlie inflammation that persists even during antiretroviral therapy (ART). It remains unclear, however, how early after HIV infection gut dysbiosis emerges and how it is affected by early ART.<h4>Methods</h4>Fecal microbiota were studied by 16s rDNA sequencing in 52 Thai ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(12):ofz367]

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Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection.

Sodsai Tovanabutra, Rujipas Sirijatuphat, Phuc T Pham, Lydia Bonar, Elizabeth A Harbolick, Meera Bose, Hongshuo Song, David Chang, Celina Oropeza, Anne Marie O'Sullivan, Joyce Balinang, Eugene Kroon, Donn J Colby, Carlo Sacdalan, Joanna Hellmuth, Phillip Chan, Peeriya Prueksakaew, Suteeraporn Pinyakorn, Linda L Jagodzinski, Duanghathai Sutthichom, Suwanna Pattamaswin, Mark de Souza, Robert A Gramzinski, Jerome H Kim, Nelson L Michael, Merlin L Robb, Nittaya Phanuphak, Jintanat Ananworanich, Victor Valcour, Gustavo H Kijak, Eric Sanders-Buell, Serena Spudich, , ,

HIV-1 disseminates to a broad range of tissue compartments during acute HIV-1 infection (AHI). The central nervous system (CNS) can serve as an early and persistent site of viral replication, which poses a potential challenge for HIV-1 remission strategies that target the HIV reservoir. CNS compartmentalization is a key feature ... Read more >>

Cells (Cells)
[2019, 8(8):]

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Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial.

Trevor A Crowell, Donn J Colby, Suteeraporn Pinyakorn, Carlo Sacdalan, Amélie Pagliuzza, Jintana Intasan, Khunthalee Benjapornpong, Kamonkan Tangnaree, Nitiya Chomchey, Eugène Kroon, Mark S de Souza, Sodsai Tovanabutra, Morgane Rolland, Michael A Eller, Dominic Paquin-Proulx, Diane L Bolton, Andrey Tokarev, Rasmi Thomas, Hiroshi Takata, Lydie Trautmann, Shelly J Krebs, Kayvon Modjarrad, Adrian B McDermott, Robert T Bailer, Nicole Doria-Rose, Bijal Patel, Robert J Gorelick, Brandie A Fullmer, Alexandra Schuetz, Pornsuk V Grandin, Robert J O'Connell, Julie E Ledgerwood, Barney S Graham, Randall Tressler, John R Mascola, Nicolas Chomont, Nelson L Michael, Merlin L Robb, Nittaya Phanuphak, Jintanat Ananworanich, ,

<h4>Background</h4>HIV-1-specific broadly neutralising antibodies such as VRC01 could promote HIV remission by halting viral replication and clearing infected cells. We investigated whether VRC01 could promote sustained viral control off antiretroviral therapy (ART) in adults who initiated ART during acute HIV infection.<h4>Methods</h4>We did a randomised, double-blind, placebo-controlled trial at the Thai ... Read more >>

Lancet HIV (The lancet. HIV)
[2019, 6(5):e297-e306]

Cited: 12 times

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Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities.

Michelle L D'Antoni, Mary Margaret Byron, Phillip Chan, Napapon Sailasuta, Carlo Sacdalan, Pasiri Sithinamsuwan, Somporn Tipsuk, Suteeraporn Pinyakorn, Eugene Kroon, Bonnie M Slike, Shelly J Krebs, Vedbar S Khadka, Thep Chalermchai, Kalpana J Kallianpur, Merlin Robb, Serena Spudich, Victor Valcour, Jintanat Ananworanich, Lishomwa C Ndhlovu, ,

<h4>Background</h4>Myeloid activation contributes to cognitive impairment in chronic human immunodeficiency virus (HIV) infection. We explored whether combination antiretroviral therapy (cART) initiation during acute HIV infection impacts CD163 shedding, a myeloid activation marker, and in turn, implications on the central nervous system (CNS).<h4>Methods</h4>We measured soluble CD163 (sCD163) levels in plasma and ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2018, 218(9):1453-1463]

Cited: 8 times

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Molecular epidemiology of a primarily MSM acute HIV-1 cohort in Bangkok, Thailand and connections within networks of transmission in Asia.

David Chang, Eric Sanders-Buell, Meera Bose, Anne Marie O'Sullivan, Phuc Pham, Eugene Kroon, Donn J Colby, Rujipas Sirijatuphat, Erik Billings, Suteeraporn Pinyakorn, Nitiya Chomchey, Wiriya Rutvisuttinunt, Gustavo Kijak, Mark de Souza, Jean-Louis Excler, Praphan Phanuphak, Nittaya Phanuphak, Robert J O'Connell, Jerome H Kim, Merlin L Robb, Nelson L Michael, Jintanat Ananworanich, Sodsai Tovanabutra, ,

<h4>Introduction</h4>Thailand plays a substantial role in global HIV-1 transmission of CRF01_AE. Worldwide, men who have sex with men (MSM) are at elevated risk for HIV-1 infection. Hence, understanding HIV-1 diversity in a primarily Thai MSM cohort with acute infection, and its connections to the broader HIV-1 transmission network in Asia ... Read more >>

J Int AIDS Soc (Journal of the International AIDS Society)
[2018, 21(11):e25204]

Cited: 1 time

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Brief Report: Safety and Tolerability of Inguinal Lymph Node Biopsy in Individuals With Acute HIV Infection in Thailand.

Michelle Chintanaphol, Carlo Sacdalan, Suthat Chottanapund, Suteeraporn Pinyakorn, Supranee Buranapraditkun, Trevor A Crowell, Eugene Kroon, Sopark Manasnayakorn, Jeffrey G Chipman, Timothy W Schacker, Nelson Michael, Nittaya Phanuphak, Serena S Spudich, Donn J Colby, Jintanat Ananworanich,

<h4>Introduction</h4>Latent HIV reservoirs are rapidly established in lymphoid tissues during acute HIV infection (AHI). Sampling these tissues provides important information about HIV pathogenesis. This period is associated with viral replication and immune activation that may affect procedure-related adverse events (AEs). We examined the safety and tolerability of inguinal lymph node ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2018, 79(2):244-248]

Cited: 3 times

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Transmission dynamics among participants initiating antiretroviral therapy upon diagnosis of early acute HIV-1 infection in Thailand.

Eugène Kroon, Phuc T Pham, Sunee Sirivichayakul, Rapee Trichavaroj, Donn J Colby, Suteeraporn Pinyakorn, Nittaya Phanuphak, Eric Sanders-Buell, Frits van Griensven, Gustavo H Kijak, Jerome H Kim, Nelson L Michael, Merlin L Robb, Jintanat Ananworanich, Mark S De Souza, Sodsai Tovanabutra, ,

<h4>Objective</h4>To assess transmission characteristics in a predominantly MSM cohort initiating antiretroviral therapy (ART) immediately following diagnosis of acute HIV-1infection (AHI).<h4>Methods</h4>A longitudinal study (2009-2017) was performed in participants with AHI (n = 439) attending a single clinic in Bangkok. Plasma samples obtained prior to ART were used to obtain HIV-1 pol sequences and ... Read more >>

AIDS (AIDS (London, England))
[2018, 32(16):2373-2381]

Cited: 2 times

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Distribution of Human Immunodeficiency Virus (HIV) Ribonucleic Acid in Cerebrospinal Fluid and Blood Is Linked to CD4/CD8 Ratio During Acute HIV.

Phillip Chan, Payal Patel, Joanna Hellmuth, Donn J Colby, Eugène Kroon, Carlo Sacdalan, Suteeraporn Pinyakorn, Linda Jagodzinski, Shelly Krebs, Jintanat Ananworanich, Victor Valcour, Serena Spudich, ,

Background:Human immunodeficiency virus (HIV) ribonucleic acid (RNA) levels in the plasma and cerebrospinal fluid (CSF) are correlated in chronic HIV infection, but their dynamics have not been characterized during acute infection. Methods:This study analyzed predictors of CSF HIV RNA and relative degree of CNS viral transmigration expressed as plasma minus ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2018, 218(6):937-945]

Cited: 1 time

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Acute Retroviral Syndrome Is Associated With High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments.

Trevor A Crowell, Donn J Colby, Suteeraporn Pinyakorn, James L K Fletcher, Eugène Kroon, Alexandra Schuetz, Shelly J Krebs, Bonnie M Slike, Louise Leyre, Nicolas Chomont, Linda L Jagodzinski, Irini Sereti, Netanya S Utay, Robin Dewar, Rungsun Rerknimitr, Nitiya Chomchey, Rapee Trichavaroj, Victor G Valcour, Serena Spudich, Nelson L Michael, Merlin L Robb, Nittaya Phanuphak, Jintanat Ananworanich, ,

Background:Many individuals with acute human immunodeficiency virus infection (AHI) experience acute retroviral syndrome (ARS), which is associated with adverse long-term clinical outcomes. Methods:Participants presenting for voluntary human immunodeficiency virus (HIV) testing were enrolled during AHI in Bangkok, Thailand. ARS was defined by ≥3 qualifying signs/symptoms. HIV burden, immunophenotypes, and biomarkers ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2018, 66(10):1540-1549]

Cited: 5 times

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Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir size.

Jeffrey E Teigler, Louise Leyre, Nicolas Chomont, Bonnie Slike, Ningbo Jian, Michael A Eller, Nittaya Phanuphak, Eugène Kroon, Suteeraporn Pinyakorn, Leigh Anne Eller, Merlin L Robb, Jintanat Ananworanich, Nelson L Michael, Hendrik Streeck, Shelly J Krebs, ,

Estimating the size of the viral reservoir is critical for HIV cure strategies. Biomarkers in peripheral circulation may give insights into the establishment of the viral reservoir in compartments not easily accessible. We therefore measured systemic levels of 84 soluble biomarkers belonging to a broad array of immune pathways in ... Read more >>

JCI Insight (JCI insight)
[2018, 3(10):]

Cited: 9 times

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Depression and Anxiety are Common in Acute HIV Infection and Associate with Plasma Immune Activation.

Joanna Hellmuth, Donn Colby, Victor Valcour, Duanghathai Suttichom, Serena Spudich, Jintanat Ananworanich, Peeriya Prueksakaew, Napapon Sailasuta, Isabel Allen, Linda L Jagodzinski, Bonnie Slike, Derek Ochi, Robert Paul, ,

This observational study of 123 Thai participants sought to determine the rate and severity of affective symptoms during acute HIV infection (AHI) and possible associations to disease mechanisms. At diagnosis, just prior to starting combination antiretroviral therapy (cART), AHI participants completed assessments of depression and anxiety symptoms that were repeated ... Read more >>

AIDS Behav (AIDS and behavior)
[2017, 21(11):3238-3246]

Cited: 6 times

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