Full Text Journal Articles by
Author Susanna Esposito

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An Unusual Dysphagia for Solids in a 17-Year-Old Girl Due To a Lusoria Artery: A Case Report and Review of the Literature.

Umberto Fanelli, Rosanna Iannarella, Aniello Meoli, Pierpacifico Gismondi, Simone Cella, Francesca Vincenzi, Susanna Esposito,

Background: Dysphagia is a condition that can have many underlying causes, often different between adults and children and its early diagnosis is crucial especially during childhood and adolescence, given the importance of proper nutritional intake to ensure adequate growth and development. Case report: We described the case of a 17-year-old ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(10):]

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Lack of viral transmission to preterm newborn from a COVID-19 positive breastfeeding mother at 11 days postpartum.

Serafina Perrone, Maurizio Giordano, Antonello Meoli, Michela Deolmi, Francesca Marinelli, Giulia Messina, Paola Lugani, Sabrina Moretti, Susanna Esposito,

In December 2019, novel coronavirus 2019 has appeared in China. On 11 February 2020, the World Health Organization officially names the disease as COVID-19.1 The new coronavirus is highly contagious. The rapid spread of SARS-CoV-2 lead to declare the pandemic on the 11th March 2020. On 10 May 2020 the ... Read more >>

J. Med. Virol. (Journal of medical virology)
[2020, :]

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School Closure During the Coronavirus Disease 2019 (COVID-19) Pandemic: An Effective Intervention at the Global Level?

Susanna Esposito, Nicola Principi,

JAMA Pediatr (JAMA pediatrics)
[2020, :]

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Immunogenicity and Safety of an MF59-adjuvanted Quadrivalent Seasonal Influenza Vaccine in Young Children at High Risk of Influenza-associated Complications: A Phase III, Randomized, Observer-blind, Multicenter Clinical Trial.

Susanna Esposito, John Fling, Kulkanya Chokephaibulkit, Marianne de Bruijn, Janine Oberye, Bin Zhang, Jeanique Vossen, Esther Heijnen, Igor Smolenov,

BACKGROUND:Vaccination against seasonal influenza is recommended for all children with a history of medical conditions placing them at increased risk of influenza-associated complications. The immunogenicity and efficacy of conventional influenza vaccines among young children are suboptimal; one strategy to enhance these is adjuvantation. We present immunogenicity and safety data for ... Read more >>

Pediatr. Infect. Dis. J. (The Pediatric infectious disease journal)
[2020, :]

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Report of a series of healthy term newborns from convalescent mothers with COVID-19.

Serafina Perrone, Michela Deolmi, Maurizio Giordano, Tiziana D'Alvano, Lucia Gambini, Mara Corradi, Tiziana Frusca, Tullio Ghi, Susanna Esposito,

BACKGROUND:The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmittable virus associated with a significantly increased risk of complications among the infected population. Few data are available for the outcome of pregnancy complicated by serious respiratory disease due to SARS-CoV-2 infection. AIM:We herein report a series of ... Read more >>

Acta Biomed (Acta bio-medica : Atenei Parmensis)
[2020, 91(2):251-255]

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Silent Sinus Syndrome and Williams Syndrome: Two Rare Diseases Found in a Pediatric Patient.

Maddalena Petraroli, Sara Riscassi, Arianna Panigari, Marilena Maltese, Susanna Esposito,

Silent sinus syndrome (SSS) is a rare disease process characterized by progressive enophthalmos and hypoglobus due to ipsilateral maxillary sinus hypoplasia and orbital floor resorption. Patients may also present with eye asymmetry, unilateral ptosis, or diplopia. Most reported cases in the literature describe its occurrence in adults, but it can ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:211]

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Recording Risk Factors of Physical Abuse in Children Younger Than 36 Months With Bone Fractures: A 12-Years Retrospective Study in an Italian General Hospital Emergency Room.

Miriam Castagnino, Alessandra Paglino, Carla Berardi, Sara Riccioni, Susanna Esposito,

Skeletal fractures (SFs) are very common in pediatrics. In some cases, they are secondary to child abuse. Differentiation of accidental from non-accidental fractures (NAFs) is essential as in abused children risk of further injuries leading to severe clinical problems and death is significant. Main objectives of this study were to ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:183]

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Paediatric Recurrent Ear, Nose and Throat Infections and Complications: Can We Do More?

Ricardo Marengo, José A Ortega Martell, Susanna Esposito,

Recurrent respiratory tract infections (rRTIs), of which there are three main groups-otitis media, tonsillitis and sinusopathies-are very common in paediatric populations and are associated with significant morbidity and mortality due to complications. These infections substantially reduce quality of life for paediatric patients and their families and are a significant personal, ... Read more >>

Infect Dis Ther (Infectious diseases and therapy)
[2020, 9(2):275-290]

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Chloroquine or hydroxychloroquine for prophylaxis of COVID-19.

Nicola Principi, Susanna Esposito,

Lancet Infect Dis (The Lancet. Infectious diseases)
[2020, :]

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Updated Management Guidelines for Clostridioides difficile in Paediatrics.

Margherita Gnocchi, Martina Gagliardi, Pierpacifico Gismondi, Federica Gaiani, Gian Luigi De' Angelis, Susanna Esposito,

Clostridioides difficile, formerly known as Clostridium difficile, causes infections (CDI) varying from self-limited diarrhoea to severe conditions, including toxic megacolon and bowel perforation. For this reason, a prompt diagnosis is fundamental to early treatment and the prevention of transmission. The aim of this article is to review diagnostic laboratory methods ... Read more >>

Pathogens (Pathogens (Basel, Switzerland))
[2020, 9(4):]

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Unsolved problems and new medical approaches to otitis media.

Nicola Principi, Susanna Esposito,

Introduction: Otitis media (OM) is a spectrum of infectious and inflammatory diseases that involve the middle ear. It includes acute otitis media (AOM), otitis media with effusion (OME) and chronic suppurative otitis media (CSOM).Areas covered: This manuscript discusses some of the emerging and unsolved problems regarding OM, and some of ... Read more >>

Expert Opin Biol Ther (Expert opinion on biological therapy)
[2020, :1-9]

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Meropenem vs standard of care for treatment of neonatal late onset sepsis (NeoMero1): A randomised controlled trial.

Irja Lutsar, Corine Chazallon, Ursula Trafojer, Vincent Meiffredy de Cabre, Cinzia Auriti, Chiara Bertaina, Francesca Ippolita Calo Carducci, Fuat Emre Canpolat, Susanna Esposito, Isabelle Fournier, Maarja Hallik, Paul T Heath, Mari-Liis Ilmoja, Elias Iosifidis, Jelena Kuznetsova, Laurence Meyer, Tuuli Metsvaht, George Mitsiakos, Zoi Dorothea Pana, Fabio Mosca, Lorenza Pugni, Emmanuel Roilides, Paolo Rossi, Kosmas Sarafidis, Laura Sanchez, Michael Sharland, Vytautas Usonis, Adilia Warris, Jean-Pierre Aboulker, Carlo Giaquinto, ,

BACKGROUND:The early use of broad-spectrum antibiotics remains the cornerstone for the treatment of neonatal late onset sepsis (LOS). However, which antibiotics should be used is still debatable, as relevant studies were conducted more than 20 years ago, recruited in single centres or countries, evaluated antibiotics not in clinical use anymore ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0229380]

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The Dose Makes the Poison: A Case Report of Acquired Methemoglobinemia.

Giulia Cannata, Luciana Abate, Chiara Scarabello, Monica Rubini, Alessandra Giacometti, Nicola Principi, Susanna Esposito, Icilio Dodi,

Background: Methemoglobinemia (MET) should be suspected in cases where cyanosis is not associated with signs and symptoms of lung and/or heart disease, or in a cyanotic child exhibiting discrepancies in the partial pressure of oxygen in the arterial blood, the blood oxygen saturation, and the clinical assessment. Case presentation: A ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(6):]

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First Case of Typhoid Fever due to Extensively Drug-resistant Salmonella enterica serovar Typhi in Italy.

Michela Procaccianti, Alice Motta, Stefano Giordani, Sara Riscassi, Battista Guidi, Monica Ruffini, Valentina Maffini, Susanna Esposito, Icilio Dodi,

Typhoid fever is a potentially severe and occasionally life-threatening bacteraemic illness caused by Salmonella enterica serovar Typhi (S. Typhi). In Pakistan, an outbreak of extensively drug-resistant (XDR) S. Typhi cases began in November 2016. We report on a five-year-old boy who contracted enteric fever while travelling in Pakistan and was ... Read more >>

Pathogens (Pathogens (Basel, Switzerland))
[2020, 9(2):]

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Updated incidence and costs of hip fractures in elderly Italian population.

Prisco Piscitelli, Cosimo Neglia, Maurizio Feola, Emanuele Rizzo, Alberto Argentiero, Mario Ascolese, Matteo Rivezzi, Cecilia Rao, Alessandro Miani, Alessandro Distante, Susanna Esposito, Giovanni Iolascon, Umberto Tarantino,

PURPOSE:We aimed at updating our previous researches about the burden of hip fractures in elderly Italian population. METHODS:We analyzed national hospitalizations records from 2000 to 2014 to compute age- and sex-specific standardized rates. RESULTS:1,335,375 hospitalizations were recorded in people ≥ 65 (1,031,816 women: 77.27% and 303,559 men: 22.73%) over 15 years, passing from ... Read more >>

Aging Clin Exp Res (Aging clinical and experimental research)
[2020, :]

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5TH ESCMID Conference on Vaccines in Bilbao, Spain. Vaccines against respiratory infections: new insights and new vaccines.

Susanna Esposito,

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2020, 16(4):899]

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Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study.

Adilia Warris, Zoi-Dorothea Pana, Andrea Oletto, Rebecca Lundin, Elio Castagnola, Thomas Lehrnbecher, Andreas H Groll, Emmanuel Roilides, Cecilie T Andersen, Maiken C Arendrup, Valentina Arsic Arsenijevic, Sonia Bianchini, Ulrich von Both, Martin Chmelnik, Tiziana Controzzi, Marieke Emonts, Susanna Esposito, Laura Ferreras-Antolin, Stefanie Henriet, Elias Iosifidis, Adam Irwin, John Kopsidas, Katrien Lagrou, Hermione Lyall, Angela Manzanares Casteleiro, Alessio Mesini, Peter Olbrich, Stephane Paulus, Karen Rokkedal Lausch, Pere Soler-Palacin, Nikos Spyridis, Volker Strenger, Martha Theodoraki, Tom Wolfs, , ,

BACKGROUND:Data on Candida bloodstream infections in pediatric patients in Europe are limited. We performed a retrospective multicenter European study of the epidemiology and outcome of neonatal and pediatric candidemia. MATERIAL AND METHODS:All first positive blood cultures from patients ≤ 18 years of age with candidemia were registered. Patients' demographic and ... Read more >>

Pediatr. Infect. Dis. J. (The Pediatric infectious disease journal)
[2020, 39(2):114-120]

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Prevalence and Clinical Outcomes of Poor Immune Response Despite Virologically Suppressive Antiretroviral Therapy Among Children and Adolescents With Human Immunodeficiency Virus in Europe and Thailand: Cohort Study.

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BACKGROUND:In human immunodeficiency virus (HIV)-positive adults, low CD4 cell counts despite fully suppressed HIV-1 RNA on antiretroviral therapy (ART) have been associated with increased risk of morbidity and mortality. We assessed the prevalence and outcomes of poor immune response (PIR) in children receiving suppressive ART. METHODS:Sixteen cohorts from the European ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(3):404-415]

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A Peculiar Case of Pneumonia due to Mycoplasma pneumoniae in a Child with Cystic Fibrosis and Sensibilization to Aspergillus fumigatus.

Laura Peccini, Serena Pennoni, Valeria Mencarini, Marco Saponara, Nicola Palladino, Nicola Principi, Guido Pennoni, Susanna Esposito,

Aspergillus fumigatus plays a major role in pulmonary exacerbations in patients with cystic fibrosis. The most common A. fumigatus diseases are those based on immune-mediated response to A. fumigatus antigens; including allergic bronchopulmonary aspergillosis (ABPA). In this condition; the presence of A. fumigatus in the lower respiratory tract triggers an ... Read more >>

Pathogens (Pathogens (Basel, Switzerland))
[2019, 9(1):]

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Pharmacy-based interventions to increase vaccine uptake: report of a multidisciplinary stakeholders meeting.

Fiona Ecarnot, Gaetano Crepaldi, Philippe Juvin, John Grabenstein, Giuseppe Del Giudice, Litjen Tan, Susan O'Dwyer, Susanna Esposito, Xavier Bosch, Gaetan Gavazzi, John Papastergiou, Jacques Gaillat, Robert Johnson, Marco Fonzo, Andrea Rossanese, Caterina Suitner, Jane Barratt, Alberta di Pasquale, Stefania Maggi, Jean-Pierre Michel,

BACKGROUND:Despite the existence of efficacious vaccines, the burden of vaccine-preventable diseases remains high and the potential health benefits of paediatric, adolescent and adult vaccination are not being achieved due to suboptimal vaccine coverage rates. Based on emerging evidence that pharmacy-based vaccine interventions are feasible and effective, the European Interdisciplinary Council ... Read more >>

BMC Public Health (BMC public health)
[2019, 19(1):1698]

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New insights into pediatric community-acquired pneumonia gained from untargeted metabolomics: A preliminary study.

Giovanni Del Borrello, Matteo Stocchero, Giuseppe Giordano, Paola Pirillo, Stefania Zanconato, Liviana Da Dalt, Silvia Carraro, Susanna Esposito, Eugenio Baraldi,

BACKGROUND:Available diagnostics often fail to distinguish viral from bacterial causes of pediatric community-acquired pneumonia (pCAP). Metabolomics, which aims at characterizing diseases based on their metabolic signatures, has been applied to expand pathophysiological understanding of many diseases. In this exploratory study, we used the untargeted metabolomic analysis to shed new light ... Read more >>

Pediatr. Pulmonol. (Pediatric pulmonology)
[2020, 55(2):418-425]

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Adjunctive therapy to treat neonatal sepsis.

Susanna Esposito, Nicola Principi,

Introduction: Neonatal sepsis (NS) is a very severe condition that causes significant morbidity and mortality.Areas covered: To overcome the limits of antibiotic therapy and improve NS outcomes, measures chosen among those theoretically able to improve host defenses or positively interfere with deleterious immune responses could be suggested. This paper discusses ... Read more >>

Expert Rev Clin Pharmacol (Expert review of clinical pharmacology)
[2020, 13(1):65-73]

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Bacterial meningitis: new treatment options to reduce the risk of brain damage.

Nicola Principi, Susanna Esposito,

Introduction: Bacterial meningitis (BM) is a medical emergency and its etiology varies according to the age group and geographic area. Studies have shown that brain damage, sequelae and neuropsychological deficits depend not only on the direct deleterious action of the pathogens, but also on the host defenses themselves.Areas covered: Corticosteroids ... Read more >>

Expert Opin Pharmacother (Expert opinion on pharmacotherapy)
[2020, 21(1):97-105]

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Vaccination against Paediatric Respiratory Pathogens.

Sonia Bianchini, Alberto Argentiero, Barbara Camilloni, Ettore Silvestri, Anna Alunno, Susanna Esposito,

Acute respiratory infections (ARIs) are extremely common in children, especially those under 5 years old. They can lead to complications, super-infection, respiratory failure, and even compromised respiratory function in adulthood. For some of the responsible pathogens, vaccines are available. This review reports current issues about vaccines against the main respiratory ... Read more >>

Vaccines (Basel) (Vaccines)
[2019, 7(4):]

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Antibiotic prescriptions in Italian hospitalised children after serial point prevalence surveys (or pointless prevalence surveys): has anything actually changed over the years?

Chiara Tersigni, Carlotta Montagnani, Patrizia D'Argenio, Marzia Duse, Susanna Esposito, Yingfen Hsia, Mike Sharland, Luisa Galli,

BACKGROUND:Point prevalence surveys have been used in several studies to provide immediate and easily comparable information about antibiotic use and showed that about one third of hospitalised children had on ongoing antimicrobial prescription during their hospital admission. The aim of this study, as part of the Global Antimicrobial Resistance, Prescribing ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2019, 45(1):127]

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