Full Text Journal Articles by
Author Suong N T Ngo

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Identifying the core concepts of pharmacology education.

Paul J White, Elizabeth A Davis, Marina Santiago, Tom Angelo, Alison Shield, Anna-Marie Babey, Barbara Kemp-Harper, Gregg Maynard, Hesham S Al-Sallami, Ian F Musgrave, Lynette B Fernandes, Suong N T Ngo, Tina Hinton,

Pharmacology education currently lacks an agreed knowledge curriculum. Evidence from physics and biology education indicates that core concepts are useful and effective structures around which such a curriculum can be designed to facilitate student learning. Building on previous work, we developed a novel, criterion-based method to identify the core concepts ... Read more >>

Pharmacol Res Perspect (Pharmacology research & perspectives)
[2021, 9(4):e00836]

Cited: 0 times

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Protective Effect of Isothiocyanates from Cruciferous Vegetables on Breast Cancer: Epidemiological and Preclinical Perspectives.

Suong N T Ngo, Desmond B Williams,

<h4>Background</h4>The effect of cruciferous vegetable intake on breast cancer survival is controversial at present. Glucosinolates are the naturally occurring constituents found across the cruciferous vegetables. Isothiocyanates are produced from the hydrolysis of glucosinolates and this reaction is catalysed by the plant-derived enzyme myrosinase. The main Isothiocyanates (ITCs) from cruciferous vegetables ... Read more >>

Anticancer Agents Med Chem (Anti-cancer agents in medicinal chemistry)
[2021, 21(11):1413-1430]

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PPAR-alpha cloning, expression, and characterization.

Suong N T Ngo, Ross A McKinnon,

Peroxisome proliferator-activated receptor α (PPARα) is a member of the nuclear/steroid receptor gene superfamily that also comprises β, δ, and γ isoforms. PPARα is a ligand-activated transcription factor that plays an important role in the regulation of many genes involved in key metabolic processes. Today, PPARα has been cloned from ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2013, 952:7-34]

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Generic substitution in the treatment of epilepsy: patient attitudes and perceptions.

Suong N T Ngo, Ieva Stupans, Ross A McKinnon,

There have been considerable debates about bioequivalence and generic substitution of certain critical care drugs. We aimed to understand patient attitudes and perceptions about generic substitution in the treatment of epilepsy. In this pilot study, a self-administered anonymous survey was completed by 47 patients with epilepsy. The response rate by ... Read more >>

Epilepsy Behav (Epilepsy & behavior : E&B)
[2013, 26(1):64-66]

Cited: 8 times

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Cytochrome P450 CYP3A in marsupials: cloning and identification of the first CYP3A subfamily member, isoform 3A70 from Eastern gray kangaroo (Macropus giganteus).

Adaweyah El-Merhibi, Suong N T Ngo, Ceilidh L Marchant, Tamara A Height, Ieva Stupans, Ross A McKinnon,

Australian marsupials are unique fauna that have evolved and adapted to unique environments and thus it is likely that their detoxification systems differ considerably from those of well-studied eutherian mammals. Knowledge of these processes in marsupials is therefore vital to understanding the consequences of exposure to xenobiotics. Cytochromes P450 (CYPs) ... Read more >>

Gene (Gene)
[2012, 506(2):423-428]

Cited: 2 times

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WITHDRAWN: Cytochrome P450 CYP3A in marsupials: Characterisation of the first identified CYP3A subfamily member, isoform 3A70 from Eastern grey kangaroo (Macropus giganteus).

Adaweyah El-Merhibi, Suong N T Ngo, Ceilidh L Marchant, Tamara A Height, Ieva Stupans, Ross A McKinnon,

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ... Read more >>

Gene (Gene)
[2011, :]

Cited: 0 times

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Rosemary and cancer prevention: preclinical perspectives.

Suong N T Ngo, Desmond B Williams, Richard J Head,

Colorectal cancer is the second leading cause of cancer death in Australia. Nutrition, particularly intake of vegetables and certain plant components, has been reported to have a major role in cancer risk reduction. Recently, there has been a growing research interest in rosemary, a common household plant grown in many ... Read more >>

Crit Rev Food Sci Nutr (Critical reviews in food science and nutrition)
[2011, 51(10):946-954]

Cited: 50 times

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Cytochrome P450 CYP3A in marsupials: cloning and characterisation of the second identified CYP3A subfamily member, isoform 3A78 from koala (Phascolarctos cinereus).

Adaweyah El-Merhibi, Suong N T Ngo, Tamara A Crittenden, Ceilidh L Marchant, Ieva Stupans, Ross A McKinnon,

Cytochromes P450 (CYPs) are critically important in the oxidative metabolism of a diverse array of xenobiotics and endogenous substrates. Previously, we cloned and characterised the CYP2C, CYP4A, and CYP4B gene subfamilies from marsupials and demonstrated important species-differences in both activity and tissue expression of these CYP enzymes. Recently, we isolated ... Read more >>

Comp Biochem Physiol C Toxicol Pharmacol (Comparative biochemistry and physiology. Toxicology & pharmacology : CBP)
[2011, 154(4):367-376]

Cited: 2 times

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Pulmonary cytochrome P450 enzymes belonging to the CYP4B subfamily from an Australian marsupial, the tammar wallaby (Macropus eugenii).

Natalie L Milic, Suong N T Ngo, Ceilidh L Marchant, Tamara A Height, Ross A McKinnon,

Cytochromes P450 (CYPs) are critically important in the oxidative metabolism of a diverse array of xenobiotics and endogenous substrates. We have previously reported the cloning and characterisation of the koala CYP4A15, the first reported member of the CYP4 family from marsupials, and have demonstrated important species differences in CYP4A activity ... Read more >>

Comp Biochem Physiol C Toxicol Pharmacol (Comparative biochemistry and physiology. Toxicology & pharmacology : CBP)
[2011, 153(1):60-66]

Cited: 1 time

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Is there variability in drug release and physical characteristics of amiodarone chloride from different commercially available tablets? Possible therapeutic implications.

Suong N T Ngo, Timothy Barnes,

<h4>Objectives</h4>Amiodarone is a low-solubility, high-permeability drug with a narrow therapeutic index and reported bioavailability problems associated with switching formulations. The aim of this study was to identify whether there is variability in drug release and physical characteristics of different commercially available amiodarone hydrochloride formulations in Australia.<h4>Methods</h4>Four available formulations (innovator Cordarone ... Read more >>

Int J Pharm Pract (The International journal of pharmacy practice)
[2010, 18(4):245-248]

Cited: 1 time

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Cloning and expression of koala (Phascolarctos cinereus) liver cytochrome P450 reductase.

Sandra Kong, Suong N T Ngo, Ross A McKinnon, Ieva Stupans,

The cloning, expression and characterization of hepatic NADPH-cytochrome P450 reductase (CPR) from koala (Phascolarctos cinereus) is described. Two 2059 bp koala liver CPR cDNAs, designated CPR1 and CPR2, were cloned by reverse transcription-polymerase chain reaction and rapid amplification of cDNA ends. The koala CPR cDNAs encode proteins of 678 amino ... Read more >>

Comp Biochem Physiol C Toxicol Pharmacol (Comparative biochemistry and physiology. Toxicology & pharmacology : CBP)
[2009, 150(1):1-9]

Cited: 4 times

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Appropriate use of non-prescription ibuprofen: a survey of patients' perceptions and understanding.

Suong N T Ngo, Ieva Stupans, Wei Sin Leong, Marwa Osman,

<h4>Objectives</h4>The aim was to investigate patients' perceptions and understanding on the appropriate use of non-prescription ibuprofen.<h4>Methods</h4>In this pilot study, a self-administered anonymous survey was completed by 183 patients presenting at one of the eight selected community pharmacy premises in South Australia and the Northern Territory during the study. The questionnaire ... Read more >>

Int J Pharm Pract (The International journal of pharmacy practice)
[2010, 18(1):63-65]

Cited: 14 times

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Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver.

Jasmina Turkanovic, Suong N T Ngo, Robert W Milne,

<h4>Objectives</h4>This study examined the effects of St John's wort (Hypericum perforatum) on the disposition of fexofenadine, a substrate of P-glycoprotein/organic anion transporting polypeptide, in the isolated perfused rat liver.<h4>Methods</h4>Male Sprague-Dawley rats were given St John's wort, 1000 mg/kg, by intragastric gavage once daily for 14 days. On day 15, livers ... Read more >>

J Pharm Pharmacol (The Journal of pharmacy and pharmacology)
[2009, 61(8):1037-1042]

Cited: 2 times

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Hepatic cytochrome P450 enzymes belonging to the CYP2C subfamily from an Australian marsupial, the koala (Phascolarctos cinereus).

Brett R Jones, Adaweyah El-Merhibi, Suong N T Ngo, Ieva Stupans, Ross A McKinnon,

Cytochromes P450 (CYPs) are critically important in the oxidative metabolism of a diverse array of xenobiotics and endogenous substrates. We have previously reported that the obligate Eucalyptus feeder koala (Phascolarctos cinereus) exhibits a higher hepatic CYP2C activity as compared to non-Eucalyptus feeders human or rat, with stimulation of CYP2C activity ... Read more >>

Comp Biochem Physiol C Toxicol Pharmacol (Comparative biochemistry and physiology. Toxicology & pharmacology : CBP)
[2008, 148(3):230-237]

Cited: 6 times

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Does garlic reduce risk of colorectal cancer? A systematic review.

Suong N T Ngo, Desmond B Williams, Lynne Cobiac, Richard J Head,

Colorectal cancer (CRC) is the 3rd leading cause of cancer death in the United States and the 2nd leading cause of cancer death in Australia. Environmental factors play important roles in the multiple-stage process of CRC and nutritional intervention has been identified as playing a major role in its prevention. ... Read more >>

J Nutr (The Journal of nutrition)
[2007, 137(10):2264-2269]

Cited: 37 times

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Alteration of fexofenadine disposition in the rat isolated perfused liver following injection of bacterial lipopolysaccharide.

Yen Tong, Ruhong Zhang, Suong N T Ngo, Andrew K Davey,

1. The aim of the present study was to examine the effect of bacterial lipopolysaccharide (LPS) on the disposition of an organic anion transporting polypeptide and P-glycoprotein substrate in the rat isolated perfused liver. 2. Male Sprague-Dawley rats were divided into four groups. Three of the groups received 1, 2.5 ... Read more >>

Clin Exp Pharmacol Physiol (Clinical and experimental pharmacology & physiology)
[2006, 33(8):685-689]

Cited: 7 times

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