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First Case of Bacteremia Caused by Coprobacillus catenaformis.

Won Young Heo, Jong Kwon Lee, Yoo Na Chung, In Young Yoo, On-Kyun Kang, Duk Hyun Sung, Sun Young Cho, Hee Jae Huh, Nam Yong Lee,

Ann Lab Med (Annals of laboratory medicine)
[2020, 40(5):421-423]

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Mean Platelet Volume in Patients with Increased Lipoprotein(a) Levels.

You La Jeon, Young Jin Kim, Sun Young Cho,

Clin. Lab. (Clinical laboratory)
[2020, 66(5):]

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A case of gonococcal meningitis caused by Neisseria gonorrhoeae MLST ST7363 in a healthy young adult.

Suhyun Oh, Si-Ho Kim, Jin Yang Baek, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Hee Jae Huh, Nam Yong Lee, Kyong Ran Peck,

A 37-year-old healthy man was admitted with fever, skin rash, migratory arthralgia, and headache without preceding urogenital symptoms. Sexual contact history and positive CSF culture for Neisseria gonorrhoeae using BacT/Alert blood culture bottles were diagnostic for gonococcal meningitis. Multilocus sequence typing of this isolate showed sequence type (ST) 7363, the ... Read more >>

J. Infect. Chemother. (Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy)
[2020, :]

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Weight-based vancomycin loading strategy may not improve achievement of optimal vancomycin concentration in patients with preserved renal function.

Si-Ho Kim, Cheol-In Kang, Soo-Hyun Lee, Joon-Sik Choi, Kyungmin Huh, Sun Young Cho, Doo Ryeon Chung, Hyo Jung Park, Soo-Youn Lee, Yae-Jean Kim, Kyong Ran Peck,

We performed a retrospective study to evaluate clinical effectiveness of vancomycin loading strategy and factors associated with achieving optimal Cmin. Patients administered vancomycin for ≥72 h from January to June 2018 were enrolled. Patients were divided into two groups: loading (LD) and non-loading (NLD). LD was defined as initial vancomycin dose ... Read more >>

J Chemother (Journal of chemotherapy (Florence, Italy))
[2020, :1-6]

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Severe Thrombocytopenia in a Patient with COVID-19.

Eliel Nham, Jae Hoon Ko, Byeong Ho Jeong, Kyungmin Huh, Sun Young Cho, Cheol In Kang, Doo Ryeon Chung, Kyong Ran Peck,

Coronavirus disease 2019 (COVID-19) outbreak is spreading rapidly all over the world, being a major threat to public health. Since clinical feature of COVID-19 has not been fully evaluated yet, empirical antibacterial agents are frequently combined for the treatment of COVID-19 in addition to antiviral agents, concerning co-existing bacterial pathogens. ... Read more >>

Infect Chemother (Infection & chemotherapy)
[2020, :]

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Risk factors for development and mortality of invasive pulmonary Aspergillosis in kidney transplantation recipients.

Hyeri Seok, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Woo Seong Huh, Jae Berm Park, Kyong Ran Peck,

Invasive pulmonary aspergillosis (IPA) is a high mortality opportunistic infection among kidney transplant recipients. This study assessed the risk factors and outcomes of IPA after KT. A retrospective study was conducted at a tertiary-care referral hospital in Korea. Electronic medical records of patients diagnosed with IPA after KT between February ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Comparison between two Rapid Urine Antigen Tests for Streptococcus pneumoniae: Immunochromatographic Test and Fluorescent-based Immunoassay.

Jae Joon Lee, Sun Young Cho, Young Jin Kim,

Clin. Lab. (Clinical laboratory)
[2020, 66(4):]

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Clinical factors influencing the performance of bacterial multiplex polymerase chain reaction in patients with community-onset pneumonia.

Ga Eun Park, Kyong Ran Peck, Jae-Hoon Ko, Cheol-In Kang, Sun Young Cho, Doo Ryeon Chung, Nam Yong Lee,

The etiologic diagnostic yield of community-onset pneumonia (COP) using conventional methods is low. Bacterial multiplex polymerase chain reaction (mPCR) has been shown to be more sensitive than conventional methods. This study assessed the clinical factors influencing bacterial mPCR results in patients with COP. Patients with COP admitted to a tertiary ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Emergence of vancomycin-resistant Enterococcus faecium ST1421 lacking the pstS gene in Korea.

Hye Mee Kim, Doo Ryeon Chung, Sun Young Cho, Kyungmin Huh, Cheol-In Kang, Kyong Ran Peck,

Although multilocus sequence typing (MLST) has been used to study molecular epidemiology and to explore the population structure of Enterococcus faecium, vancomycin-resistant E. faecium (VREF) strains lacking the pstS gene that were non-typable using conventional MLST methods were reported recently. We found nationwide emergence of VREF isolates lacking pstS in ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Characteristics and Clinical Outcomes of Extended-Spectrum beta-lactamase-producing Klebsiella pneumoniae Bacteremia in Cancer Patients.

Eliel Nham, Kyungmin Huh, Sun Young Cho, Doo Ryeon Chung, Kyong Ran Peck, Nam Yong Lee, Cheol In Kang,

Cancer patients can be at a higher risk of infection due to drug-resistant bacteria than the general population for various reasons. We performed a retrospective study to evaluate possible risk factors and outcomes of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-KP) bacteremia in cancer patients. Cases were divided into two groups based ... Read more >>

Infect Chemother (Infection & chemotherapy)
[2020, 52(1):59-69]

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Hepcidin and Neutrophil Gelatinase-Associated Lipocalin as a Biomarker for Acute Kidney Injury Linked Iron Metabolism.

Sun Young Cho, Mina Hur,

Ann Lab Med (Annals of laboratory medicine)
[2020, 40(2):97-98]

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Impact of difficult-to-treat resistance in gram-negative bacteremia on mortality: retrospective analysis of nationwide surveillance data.

Kyungmin Huh, Doo Ryeon Chung, Young Eun Ha, Jae-Hoon Ko, Si-Ho Kim, Min-Ji Kim, Hee Jae Huh, Nam Yong Lee, Sun Young Cho, Cheol-In Kang, Kyong Ran Peck, Jae-Hoon Song, ,

BACKGROUND:Clinically relevant categorization of antimicrobial resistance is critical to mitigating the threat it poses. Difficult-to-treat resistance (DTR) is a recently proposed category defined as non-susceptibility to all first-line antibiotic agents. METHODS:A retrospective study was conducted with non-duplicate cases of gram-negative bloodstream infection (GNBSI) caused by four major taxa (Escherichia coli, ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Comparison of 16S Ribosomal RNA Targeted Sequencing and Culture for Bacterial Identification in Normally Sterile Body Fluid Samples: Report of a 10-Year Clinical Laboratory Review.

In Young Yoo, On Kyun Kang, Myoung Keun Lee, Yae Jean Kim, Sun Young Cho, Kyungmin Huh, Cheol In Kang, Doo Ryeon Chung, Kyong Ran Peck, Hee Jae Huh, Nam Yong Lee,

As 16S ribosomal RNA (rRNA)-targeted sequencing can detect DNA from non-viable bacteria, it can be used to identify pathogens from clinical samples even in patients pretreated with antibiotics. We compared the results of 16S rRNA-targeted sequencing and culture for identifying bacterial species in normally sterile body fluid (NSBF): cerebrospinal, pericardial, ... Read more >>

Ann Lab Med (Annals of laboratory medicine)
[2020, 40(1):63-67]

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Antifungal prophylaxis with posaconazole tablet and oral suspension in patients with haematologic malignancy: Therapeutic drug monitoring, efficacy and risk factors for the suboptimal level.

Jihyu Oh, Cheol-In Kang, Si-Ho Kim, Kyungmin Huh, Sun Young Cho, Doo Ryeon Chung, Soo-Youn Lee, Chul Won Jung, Kyong Ran Peck,

BACKGROUND:Posaconazole is used to prevent invasive fungal infections (IFIs) in patients with haematologic malignancy. In this study, we compared plasma posaconazole concentrations (PPCs) and the incidence of breakthrough IFIs between patients with haematologic malignancy receiving posaconazole oral suspension vs tablet. METHODS:We retrospectively collected data on adult patients with haematologic malignancies ... Read more >>

Mycoses (Mycoses)
[2020, 63(1):89-94]

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1701. Differences in Diagnostic Performance of β-d-Glucan Testing in Patients with Varying Degrees of Susceptibility to Invasive Fungal Infections.

Eliel Nham, Si-Ho Kim, Hyunjoo Lee, Jae-Hoon Ko, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck,

AbstractBackgroundUsefulness of β-d-glucan (BDG) testing in high-risk patients for invasive fungal infection (IFI) diagnosis has been well demonstrated. However, data on its usefulness in patients without risk factors are limited. We evaluated differences in the diagnostic performance of BDG testing in patients with varying degrees of susceptibility to IFI.MethodsFrom April ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S623-S623]

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228. Early Recurrent Postoperative Bloodstream infections in Living-Donor Liver Transplant Recipients.

Si-Ho Kim, Seokjun Mun, Hyunjoo Lee, Eliel Nam, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck,

AbstractBackgroundBloodstream infections (BSIs) represent a poor prognosis in living-donor liver transplant recipients (LDLT-Rs). Some patients develop recurrent BSIs. We evaluated the impacts of ER-BSIs on outcomes in LDLT-Rs.MethodsAll LDLT-Rs with follow-up data between January 2008 and December 2016 were included. Early BSIs (E-BSIs) defined as BSI events within 2 months ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S132-S132]

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Clinical effectiveness of oral antimicrobial therapy for acute pyelonephritis caused by extended-spectrum β-lactamase-producing Enterobacteriales.

Si-Ho Kim, Kyoung Ree Lim, Hyunju Lee, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck,

Infections caused by extended-spectrum β-lactamase-producing Enterobacteriales (ESBL-PE) are commonly treated with intravenous antibiotics. This study investigated whether oral antimicrobial therapy (OAT) is as effective as intravenous antimicrobial therapy (IVT) for acute pyelonephritis (APN) caused by ESBL-PE. A retrospective cohort of patients with APN caused by ESBL-PE was studied at a ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, 39(1):159-167]

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Evaluating the optimal dose of teicoplanin with therapeutic drug monitoring: not too high for adverse event, not too low for treatment efficacy.

Si-Ho Kim, Cheol-In Kang, Kyungmin Huh, Sun Young Cho, Doo Ryeon Chung, Soo-Youn Lee, Yae-Jean Kim, Kyong Ran Peck,

Therapeutic drug monitoring (TDM) of teicoplanin is aimed at minimizing the clinical impact of pharmacokinetic variability; however, its benefits are still being defined. We performed a retrospective study of teicoplanin TDM focusing on the dose-serum concentration relationship and clinical outcomes in a clinical setting. From January 2017 to December 2018, ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2019, 38(11):2113-2120]

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Effects of environmental disinfection on the isolation of vancomycin-resistant Enterococcus after a hospital-associated outbreak of Middle East respiratory syndrome.

Jae-Hoon Ko, Si-Ho Kim, Nam Yong Lee, Yae-Jin Kim, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck,

Environmental disinfection with sodium hypochlorite and hydrogen peroxide vapor was performed after a hospital-associated outbreak of Middle East respiratory syndrome. Although only 11% of total beds were disinfected, the isolation and vancomycin-resistance rates of Enterococcus spp significantly decreased for 2 months, whereas other multidrug-resistant organisms did not. ... Read more >>

Am J Infect Control (American journal of infection control)
[2019, 47(12):1516-1518]

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Treatment of community-onset pneumonia in neutropenic cancer patients: β-lactam monotherapy versus combination antibiotic regimens.

Hyeri Seok, Jae-Hoon Ko, Kyong Ran Peck, Ji-Yeon Kim, Ji Hye Lee, Ga Eun Park, Sun Young Cho, Cheol-In Kang, Nam Yong Lee, Doo Ryeon Chung,

Background:Although β-lactam monotherapy may be sufficient in non-critically ill patients with community-acquired pneumonia, the value of combination antibiotic regimens in community-onset neutropenic pneumonia remains unclear. Methods:A retrospective cohort study was conducted to compare the effects of combination antibiotic regimens to those of β-lactam monotherapy in cancer patients with community-onset neutropenic ... Read more >>

Pneumonia (Nathan) (Pneumonia (Nathan Qld.))
[2019, 11:2]

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Expanded Impacts of Platelet Functions: Beyond Hemostasis and Thrombosis.

Sun Young Cho, Mina Hur,

Ann Lab Med (Annals of laboratory medicine)
[2019, 39(4):343-344]

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Poor prognosis of Candida tropicalis among non-albicans candidemia: a retrospective multicenter cohort study, Korea.

Jae-Hoon Ko, Dong Sik Jung, Ji Yeon Lee, Hyun Ah Kim, Seong Yeol Ryu, Sook-In Jung, Eun-Jeong Joo, Shinhye Cheon, Yeon-Sook Kim, Shin-Woo Kim, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Nam Yong Lee, Kyong Ran Peck,

To evaluate clinical features and prognostic factors of non-albicans candidemia, we conducted a retrospective multicenter cohort study at 7 university hospitals in Korea from January 2010 to February 2016. A total of 721 patients with non-albicans candidemia were included in the analysis. C. tropicalis was most commonly identified (36.5%), followed ... Read more >>

Diagn. Microbiol. Infect. Dis. (Diagnostic microbiology and infectious disease)
[2019, 95(2):195-200]

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Plasmid analysis of Escherichia coli isolates from South Korea co-producing NDM-5 and OXA-181 carbapenemases.

Jin Yang Baek, Sun Young Cho, So Hyun Kim, Cheol-In Kang, Kyong Ran Peck, Jae-Hoon Song, Doo Ryeon Chung, Kwan Soo Ko,

Recently, Escherichia coli isolates co-producing New Delhi metallo-β-lactamase (NDM)-5 and oxacillinase (OXA)-181 were identified in a tertiary-care hospital of South Korea. Isolate CC1702-1 was collected from urine in January 2017 and isolate CC1706-1 was recovered from a transtracheal aspirate of a hospitalized patient in May 2017. Carbapenemase genes were identified ... Read more >>

Plasmid (Plasmid)
[2019, 104:102417]

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Staphylococcal scarlet fever associated with staphylococcal enterotoxin M in an elderly patient.

Seok Jun Mun, Si-Ho Kim, Jin Yang Baek, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck,

Staphylococcal scarlet fever (SSF) is characterized by an exanthem without enanthem, bullae, or exfoliation, and is known to be related to Staphylococcus aureus toxins, especially superantigens. It has been reported in children and young adults. Herein, we report the first case of an elderly patient with SSF caused by staphylococcal ... Read more >>

Int. J. Infect. Dis. (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2019, 85:7-9]

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Preoperative Mean Platelet Volume in Thyroid Cancer.

Jae Joon Lee, Anbok Lee, Sun Young Cho,

Clin. Lab. (Clinical laboratory)
[2019, 65(5):]

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