Full Text Journal Articles by
Author Sujit Pujhari

Advertisement

Find full text journal articles








Mice with humanized-lungs and immune system - an idealized model for COVID-19 and other respiratory illness.

Sujit Pujhari, Jason L Rasgon,

Lack of an appropriate animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent responsible for COVID-19 pandemic disease, represents a significant hurdle in the process of understanding disease biology and evaluating therapeutic and preventive candidates. It is time for public health agencies to revisit regulation ... Read more >>

Virulence (Virulence)
[2020, 11(1):486-488]

Cited: 0 times

View full text PDF listing >>



Cas9-Mediated Gene-Editing in the Malaria Mosquito Anopheles stephensi by ReMOT Control.

Vanessa M Macias, Sage McKeand, Duverney Chaverra-Rodriguez, Grant L Hughes, Aniko Fazekas, Sujit Pujhari, Nijole Jasinskiene, Anthony A James, Jason L Rasgon,

Innovative tools are essential for advancing malaria control and depend on an understanding of molecular mechanisms governing transmission of malaria parasites by Anopheles mosquitoes. CRISPR/Cas9-based gene disruption is a powerful method to uncover underlying biology of vector-pathogen interactions and can itself form the basis of mosquito control strategies. However, embryo ... Read more >>

G3 (Bethesda) (G3 (Bethesda, Md.))
[2020, 10(4):1353-1360]

Cited: 0 times

View full text PDF listing >>



Advertisement

Cas9-mediated gene-editing in the malaria mosquito Anopheles stephensi by ReMOT Control

Vanessa Macias, Sage McKeand, Duverney Chaverra-Rodriguez, Grant Hughes, Aniko Fazekas, Sujit Pujhari, Nijole Jasinskiene, Anthony James, Jason Rasgon,

Abstract Innovative tool development is essential for continued advancement in malaria control and depends on a deeper understanding of the molecular mechanisms that govern transmission of malaria parasites by Anopheles mosquitoes. Targeted disruption of genes in mosquito vectors is a powerful method to uncover the underlying biology of vector-pathogen interactions, ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing.

Duverney Chaverra-Rodriguez, Vanessa M Macias, Grant L Hughes, Sujit Pujhari, Yasutsugu Suzuki, David R Peterson, Donghun Kim, Sage McKeand, Jason L Rasgon,

Cas9-mediated gene editing is a powerful tool for addressing research questions in arthropods. Current approaches rely upon delivering Cas9 ribonucleoprotein (RNP) complex by embryonic microinjection, which is challenging, is limited to a small number of species, and is inefficient even in optimized taxa. Here we develop a technology termed Receptor-Mediated ... Read more >>

Nat Commun (Nature communications)
[2018, 9(1):3008]

Cited: 6 times

View full text PDF listing >>



Anopheles Mosquitoes May Drive Invasion and Transmission of Mayaro Virus across Geographically Diverse Regions

Marco Brustolin, Sujit Pujhari, Cory Henderson, Jason Rasgon,

Abstract The Togavirus (Alphavirus) Mayaro virus (MAYV) was initially described in 1954 from Mayaro County (Trinidad) and has been responsible for outbreaks in South America and the Caribbean. Imported MAYV cases are on the rise, leading to invasion concerns similar to Chikungunya and Zika viruses. Little is known about the ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Anti-apoptosis in porcine respiratory and reproductive syndrome virus.

Sujit Pujhari, Jason L Rasgon, Alexander N Zakhartchouk,

Virulence (Virulence)
[2016, 7(5):610-611]

Cited: 1 time

View full text PDF listing >>



Zika virus: A newly emergent vector-borne public health threat in the Americas

Sujit Pujhari, Jason Rasgon,

Zika virus is a newly emergent mosquito-borne flavivirus. Once almost ignored epidemiologically, recent major outbreaks and links to neurological birth defects have focused attention on this neglected pathogen. We review the discovery, biology and symptomatology of Zika virus, what is known and not known about the mosquitoes that transmit the ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Role of phosphatidylinositol-3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) signalling pathways in porcine reproductive and respiratory syndrome virus (PRRSV) replication.

Sujit Pujhari, Marko Kryworuchko, Alexander N Zakhartchouk,

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is a positive sense, single-stranded RNA genome virus that has become a major infection in swine, exerting huge economic losses to the industry worldwide. Detailed knowledge concerning the molecular mechanisms by which the virus manipulates the host cell signals transduction machinery is not ... Read more >>

Virus Res. (Virus research)
[2014, 194:138-144]

Cited: 9 times

View full text PDF listing >>



Clinical applicability of various dengue diagnostic tests in resource-limited endemic settings.

Baijayantimala Mishra, Puneet K Gupta, Vandana Dhiman, Sujit K Pujhari, Mirnalini Sharma, Radha K Ratho,

INTRODUCTION: Dengue is one of the most important arboviral infections caused by one of the four dengue serotypes, 1-4. OBJECTIVE: To study the applicability of different diagnostic methods in diagnosis of dengue viral infection. MATERIALS AND METHODS: A total of 2101 blood samples were collected for confirmation of dengue viral ... Read more >>

J Glob Infect Dis (Journal of global infectious diseases)
[2014, 6(3):109-113]

Cited: 6 times

View full text PDF listing >>



Th1 immune response takeover among patients with severe Japanese encephalitis infection.

Sujit Kumar Pujhari, Sudesh Prabhakar, Radhakanta Ratho, Baijayantimala Mishra, Manish Modi, Sandeep Sharma, Paramjeet Singh,

The present study was intended to explore the dynamics of viral and host factors determining the outcome of Japanese encephalitis viral infection. 223 patients with acute encephalitic syndrome, 126 with febrile illness suspected of JE and 79 apparently healthy individuals as control were enrolled. Elevated levels of TNF-α and IL-6 ... Read more >>

J. Neuroimmunol. (Journal of neuroimmunology)
[2013, 263(1-2):133-138]

Cited: 3 times

View full text PDF listing >>



Genotyping and subtyping of mumps virus isolates from the Indian subcontinent.

Baijayantimala Mishra, Sujit Kumar Pujhari, Vandana Dhiman, P Mahalakshmi, Abhinav Bharadwaj, Sandeep Pokhrel, Deepak Sharma, Mirnalini Sharma, Deepak Bhatia, Radha Kanta Ratho,

Mumps is a vaccine-preventable disease that usually occurs as a self-limiting parotitis, but it can also lead to several life-threatening complications, including pancreatitis, meningitis, and encephalitis. The molecular epidemiology of the virus is poorly understood. The present study describes an outbreak of mumps virus infection in Punjab, India. The etiology ... Read more >>

Arch. Virol. (Archives of virology)
[2013, 158(11):2359-2363]

Cited: 9 times

View full text PDF listing >>



Hepatitis E virus antigen detection as an early diagnostic marker: report from India.

Manasi Majumdar, Mini P Singh, Sujit Kumar Pujhari, Deepak Bhatia, Y Chawla, R K Ratho,

Hepatitis E virus (HEV) is implicated in many outbreaks of viral hepatitis in the Indian subcontinent. The conventional diagnosis of such outbreaks rests on the detection of anti-HEV IgM antibodies. However, IgM antibodies develop after 4-5 days of infection. An early-diagnostic marker is imperative for timely diagnosis of the outbreak ... Read more >>

J. Med. Virol. (Journal of medical virology)
[2013, 85(5):823-827]

Cited: 13 times

View full text PDF listing >>



Development of a DNA-launched replicon as a vaccine for porcine reproductive and respiratory syndrome virus.

Sujit Pujhari, Tayyba T Baig, Satynder Hansra, Alexander N Zakhartchouk,

Though a modified live attenuated vaccine (MLV) is available against porcine reproductive and respiratory syndrome virus (PRRSV), its limitations in protective efficacy, safety and few others warrant the development of newer vaccines. In this study, we have constructed a propagation-defective DNA-launched PRRSV replicon as a vaccine candidate and evaluated its ... Read more >>

Virus Res. (Virus research)
[2013, 173(2):321-326]

Cited: 2 times

View full text PDF listing >>



Molecular detection and sequence analysis of hepatitis E virus in patients with viral hepatitis from North India.

Subrat Kumar, Sujit Kumar Pujhari, Yogesh Kumar Chawla, Anuradha Chakraborti, Radha Kanta Ratho,

Viral hepatitis is a major cause of mortality and morbidity in developing countries. Hepatitis E virus (HEV) is responsible for both sporadic and epidemic outbreaks of viral hepatitis in India. Here a total of 843 samples were collected: 685 from patients with acute viral hepatitis (AVH), 70 from patients with ... Read more >>

Diagn. Microbiol. Infect. Dis. (Diagnostic microbiology and infectious disease)
[2011, 71(2):110-117]

Cited: 7 times

View full text PDF listing >>



Utility of multiplex reverse transcriptase-polymerase chain reaction for diagnosis and serotypic characterization of dengue and chikungunya viruses in clinical samples.

Baijayantimala Mishra, Mirnalini Sharma, Sujit Kumar Pujhari, Radha Kanta Ratho, Dvr Sai Gopal, Cvm Naresh Kumar, Gita Sarangi, Nirupama Chayani, Subhash C Varma,

The reemergence of chikungunya virus (CHIKV) has compounded the already existing dengue problem because of clinical similarities and common vector, demanding the need for a rapid and specific diagnosis. Thus, dengue chikungunya multiplex reverse transcriptase-polymerase chain reaction (DCmRT-PCR) was developed and validated for simultaneous detection of dengue and chikungunya viral ... Read more >>

Diagn. Microbiol. Infect. Dis. (Diagnostic microbiology and infectious disease)
[2011, 71(2):118-125]

Cited: 11 times

View full text PDF listing >>



Clinical applicability of single-tube multiplex reverse-transcriptase PCR in dengue virus diagnosis and serotyping.

Bajayantimala Mishra, Mirnalini Sharma, Sujit Kumar Pujhari, Suma B Appannanavar, Radha Kanta Ratho,

This study has evaluated the clinical applicability of a single-tube multiplex RT-PCR as compared with a two-step nested RT-PCR for the diagnosis as well as serotyping of dengue virus in patient's samples. Seventy-six acute phase blood samples collected from clinically suspected dengue patients during the 2008 outbreak were subjected to ... Read more >>

J. Clin. Lab. Anal. (Journal of clinical laboratory analysis)
[2011, 25(2):76-78]

Cited: 5 times

View full text PDF listing >>



Phylogenetic analysis and subtyping of acute and fulminant strains of hepatitis E virus isolates of North India with reference to disease severity.

Sujit Kumar Pujhari, Subrat Kumar, Radha Kanta Ratho, Yogesh Kumar Chawla, Anuradha Chakraborti,

Hepatitis E is endemic to the Indian subcontinent, with a seroprevalence of 4-20%, and more than 25% of acute viral hepatitis is due to HEV. The northern parts of India have been experiencing outbreaks and sporadic cases of HEV since 1955. In a total of sixteen HEV sequences, ten acute ... Read more >>

Arch. Virol. (Archives of virology)
[2010, 155(9):1483-1486]

Cited: 9 times

View full text PDF listing >>





Advertisement

Disclaimer
0.7867 s