Full Text Journal Articles by
Author Sue A Shapses

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Perspective: US Documentation and Regulation of Human Nutrition Randomized Controlled Trials.

Connie M Weaver, Naomi K Fukagawa, DeAnn Liska, Richard D Mattes, Gregory Matuszek, Jeri W Nieves, Sue A Shapses, Linda G Snetselaar,

Training to ensure good documentation practices and adherence to regulatory requirements in human nutrition randomized controlled trials has not been given sufficient attention. Furthermore, it is difficult to find this information conveniently organized or in a form relevant to nutrition protocols. Current gaps in training and research surveillance exist in ... Read more >>

Adv Nutr (Advances in nutrition (Bethesda, Md.))
[2021, 12(1):21-45]

Cited: 4 times

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Low-vitamin-D diet lowers cerebral serotonin concentration in mature female mice.

Yang Wang, Joshua W Miller, Nicholas T Bello, Sue A Shapses,

Low circulating 25-hydroxyvitamin D (25OHD) is commonly found in obese individuals and is often attributed to a volume dilution effect of adipose tissue. However, low vitamin D (LD) intake may contribute to the obesity itself. In this study, we examine whether low vitamin D status contributes to increased food intake ... Read more >>

Nutr Res (Nutrition research (New York, N.Y.))
[2020, 81:71-80]

Cited: 1 time

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Vitamin D deficiency is associated with reduced mobility after hip fracture surgery: a prospective study.

Lihong Hao, Jeffrey L Carson, Yvette Schlussel, Helaine Noveck, Sue A Shapses,

<h4>Background</h4>Hip fractures are associated with a high rate of morbidity and mortality, and successful ambulation after surgery is an important outcome in this patient population.<h4>Objective</h4>This study aims to determine whether 25-hydroxyvitamin D [25(OH)D] concentration or the Geriatric Nutritional Risk Index (GNRI) is associated with mortality or rates of walking in ... Read more >>

Am J Clin Nutr (The American journal of clinical nutrition)
[2020, 112(3):613-618]

Cited: 6 times

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Serum Klotho levels in primary hyperparathyroidism patients before and after parathyroidectomy.

Chi Su, Lingqiong Meng, Stanley Z Trooskin, Sue A Shapses, Yuling He, Aseel Al-Dayyeni, Xiangbing Wang,

<h4>Purpose</h4>To investigate Klotho level and its association with biochemical indices of primary hyperparathyroidism (PHPT).<h4>Methods</h4>Fifty PHPT patients and fifty-two age- and body mass index-(BMI) matched healthy control subjects were recruited. In addition, twenty-five PHPT patients underwent parathyroidectomy (PTX) and had 4-month follow-up visits. Intact parathyroid hormone (iPTH), 25-hydroxyvitamin D [25(OH)D], calcium, ... Read more >>

Endocrine (Endocrine)
[2020, 70(2):421-425]

Cited: 1 time

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Administration of Denosumab Preserves Bone Mineral Density at the Knee in Persons With Subacute Spinal Cord Injury: Findings From a Randomized Clinical Trial.

Christopher M Cirnigliaro, Michael F La Fountaine, J Scott Parrott, Steven C Kirshblum, Cristin McKenna, Susan J Sauer, Sue A Shapses, Lihong Hao, Isa A McClure, Joshua C Hobson, Ann M Spungen, William A Bauman,

Persons with neurologically motor-complete spinal cord injury (SCI) have a marked loss of bone mineral density (BMD) of the long bones of the lower extremities, predisposing them to fragility fractures, especially at the knee. Denosumab, a commercially available human monoclonal IgG antibody to receptor activator of nuclear factor-κB ligand (RANKL), ... Read more >>

JBMR Plus (JBMR plus)
[2020, 4(8):e10375]

Cited: 1 time

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MON-388 Total and Free 1,25dihydroxyvitamin D Levels in Postmenopausal Patients with Primary Hyperparathyroidism

Lingqiong Meng, Sue A Shapses, Xiangbing Wang,

Abstract Background: Vitamin D3 is metabolized to 25-hydroxyvitamin D [25(OH)D] in liver, and only after it goes to kidney is it converted to its biologically active form, 1,25-dihydroxyvitamin D [1,25(OH)2D]. Also, the majority of both total 25(OH)D and 1,25(OH)2D are tightly bound to vitamin D bind protein (DBP) and only ... Read more >>

J Endocr Soc (Journal of the Endocrine Society)
[2020, 4(Suppl 1):]

Cited: 0 times

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Do We Need to Be Concerned about Bone Mineral Density in Vegetarians and Vegans?

Sue A Shapses,

J Nutr (The Journal of nutrition)
[2020, 150(5):983-984]

Cited: 2 times

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Three Doses of Vitamin D and Cognitive Outcomes in Older Women: A Double-Blind Randomized Controlled Trial.

Monica Castle, Nancy Fiedler, Lilliana Claudia Pop, Stephen J Schneider, Yvette Schlussel, Deeptha Sukumar, Lihong Hao, Sue A Shapses,

Vitamin D may affect cognitive performance, but previous studies are either short term or observational. We conducted a randomized controlled trial of vitamin D supplementation on domain-specific cognitive measures in postmenopausal women. Overweight/obese women with serum 25-hydroxyvitamin D (25OHD) levels less than 30 ng/mL were recruited. Vitamin D3 supplementation (600, ... Read more >>

J Gerontol A Biol Sci Med Sci (The journals of gerontology. Series A, Biological sciences and medical sciences)
[2020, 75(5):835-842]

Cited: 5 times

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Lower total 25-hydroxyvitamin D but no difference in calculated or measured free 25-hydroxyvitamin D serum levels in patients with primary hyperparathyroidism.

Lingqiong Meng, Chi Su, Sue A Shapses, Aseel Al-Dayyeni, Yuling He, Xiangbing Wang,

To evaluate the measured free 25-hydroxyvitamin D [25(OH)D] levels in patients with hyperparathyroidism (PHPT) and healthy controls. Eighty patients with PHPT(n = 40) and age and BMI matched controls (n = 40) were examined. Serum levels of total or free 25(OH)D, vitamin D binding protein (DBP), intact parathyroid hormone (iPTH) ... Read more >>

J Steroid Biochem Mol Biol (The Journal of steroid biochemistry and molecular biology)
[2020, 199:105616]

Cited: 1 time

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LOW FREE (BUT NOT TOTAL) 25-HYDROXYVITAMIN D LEVELS IN SUBJECTS WITH NORMOCALCEMIC HYPERPARATHYROIDISM.

Xiangbing Wang, Lingqiong Meng, Chi Su, Sue A Shapses,

<b><i>Objective:</i></b> Normocalcemic primary hyperparathyroidism (NPHPT) is characterized by elevated parathyroid hormone (PTH) levels with persistently normal calcium levels. The diagnosis of NPHPT assumes the absence of secondary causes of elevated PTH levels. The objective of the current study was to examine levels of free 25-hydroxyvitamin D (25[OH]D) in NPHPT subjects ... Read more >>

Endocr Pract (Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists)
[2020, 26(2):174-178]

Cited: 7 times

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Effect of Weight Change Following Intentional Weight Loss on Bone Health in Older Adults with Obesity.

Daniel E Kammire, Michael P Walkup, Walter T Ambrosius, Leon Lenchik, Sue A Shapses, Barbara J Nicklas, Denise K Houston, Anthony P Marsh, W Jack Rejeski, Kristen M Beavers,

OBJECTIVE:This study aimed to examine change in bone mineral density (BMD) and trabecular bone score among older adult weight regainers (WR) and weight maintainers (WM). METHODS:Observational data come from 77 older adults (mean age: 67 [SD 5] years; 69% women; 70% white) with obesity (mean BMI: 33.6 [SD  3.7] kg/m2 ) who lost ... Read more >>

Obesity (Silver Spring) (Obesity (Silver Spring, Md.))
[2019, 27(11):1839-1845]

Cited: 6 times

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Fruits, vegetables, and health: A comprehensive narrative, umbrella review of the science and recommendations for enhanced public policy to improve intake.

Taylor C Wallace, Regan L Bailey, Jeffrey B Blumberg, Britt Burton-Freeman, C-Y Oliver Chen, Kristi M Crowe-White, Adam Drewnowski, Shirin Hooshmand, Elizabeth Johnson, Richard Lewis, Robert Murray, Sue A Shapses, Ding Ding Wang,

Fruit and vegetables (F&V) have been a cornerstone of healthy dietary recommendations; the 2015-2020 U.S. Dietary Guidelines for Americans recommend that F&V constitute one-half of the plate at each meal. F&V include a diverse collection of plant foods that vary in their energy, nutrient, and dietary bioactive contents. F&V have potential ... Read more >>

Crit Rev Food Sci Nutr (Critical reviews in food science and nutrition)
[2020, 60(13):2174-2211]

Cited: 36 times

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Urinary mycoestrogens and age and height at menarche in New Jersey girls.

Zorimar Rivera-Núñez, Emily S Barrett, Elizabeth A Szamreta, Sue A Shapses, Bo Qin, Yong Lin, Helmut Zarbl, Brian Buckley, Elisa V Bandera,

<h4>Background</h4>Despite evidence of the endocrine disrupting properties of zearalenone (ZEN) and alpha-zearalanol (zeranol, α-ZAL), they have been minimally studied in human populations. In previous cross-sectional analyses, we demonstrated that 9-10 years old girls with detectable urinary ZEN were of shorter stature and less likely to have reached the onset of breast ... Read more >>

Environ Health (Environmental health : a global access science source)
[2019, 18(1):24]

Cited: 4 times

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25-Hydroxyvitamin D and Vitamin D Binding Protein Levels in Patients With Primary Hyperparathyroidism Before and After Parathyroidectomy.

Xiangbing Wang, Zhifeng Sheng, Lingqiong Meng, Chi Su, Stanley Trooskin, Sue A Shapses,

<b>Objective:</b> To evaluate vitamin D binding protein and free 25-hydroxyvitamin D [25(OH)D] levels in healthy controls compared to primary hyperparathyroidism (PHPT) patients, and to examine PHPT before and after surgery. <b>Methods:</b> Seventy-five PHPT patients and 75 healthy age, gender, and body mass index (BMI) -matched control subjects were examined. In ... Read more >>

Front Endocrinol (Lausanne) (Frontiers in endocrinology)
[2019, 10:171]

Cited: 1 time

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Effect of a hypocaloric, nutritionally complete, higher-protein meal plan on bone density and quality in older adults with obesity: a randomized trial.

Ashley A Weaver, Denise K Houston, Sue A Shapses, Mary F Lyles, Rebecca M Henderson, Daniel P Beavers, Arlynn C Baker, Kristen M Beavers,

<h4>Background</h4>Dietary protein and micronutrients are important to the maintenance of bone health and may be an effective countermeasure to weight-loss-associated bone loss.<h4>Objectives</h4>We aimed to determine the effect of a 6-mo hypocaloric, nutritionally complete, higher-protein meal plan on change in bone density and quality as compared with weight stability in older ... Read more >>

Am J Clin Nutr (The American journal of clinical nutrition)
[2019, 109(2):478-486]

Cited: 8 times

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Expression of vitamin D hydroxylases and bone quality in obese mice consuming saturated or monounsaturated enriched high-fat diets.

Yang Wang, Patricia Buckendahl, Kajal Sharma, Joshua W Miller, Sue A Shapses,

Obesity induced by high-fat diets (HFDs) is inversely associated with vitamin D status and bone health. However, the associations and effects of excessive fat intake on hepatic and renal vitamin D metabolism have not been addressed. The primary objective was to determine if excessive energy and fat intake, or the ... Read more >>

Nutr Res (Nutrition research (New York, N.Y.))
[2018, 60:106-115]

Cited: 1 time

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Effect of Exercise Modality During Weight Loss on Bone Health in Older Adults With Obesity and Cardiovascular Disease or Metabolic Syndrome: A Randomized Controlled Trial.

Kristen M Beavers, Michael P Walkup, Ashley A Weaver, Leon Lenchik, Stephen B Kritchevsky, Barbara J Nicklas, Walter T Ambrosius, Joel D Stitzel, Thomas C Register, Sue A Shapses, Anthony P Marsh, W Jack Rejeski,

The objective of this study was to determine the ability of either aerobic or resistance training to counter weight-loss-associated bone loss in older adults. There were 187 older adults (67 years, 70% women, 64% white) with obesity (BMI = 34.5 ± 3.7 kg/m<sup>2</sup> ) and cardiovascular disease and/or metabolic syndrome who were randomized to participate ... Read more >>

J Bone Miner Res (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research)
[2018, 33(12):2140-2149]

Cited: 13 times

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Animal versus plant protein and adult bone health: A systematic review and meta-analysis from the National Osteoporosis Foundation.

Marissa M Shams-White, Mei Chung, Zhuxuan Fu, Karl L Insogna, Micaela C Karlsen, Meryl S LeBoff, Sue A Shapses, Joachim Sackey, Jian Shi, Taylor C Wallace, Connie M Weaver,

<h4>Background</h4>Protein may have both beneficial and detrimental effects on bone health depending on a variety of factors, including protein source.<h4>Objective</h4>The aim was to conduct a systematic review and meta-analysis evaluating the effects of animal versus plant protein intake on bone mineral density (BMD), bone mineral content (BMC) and select bone ... Read more >>

PLoS One (PloS one)
[2018, 13(2):e0192459]

Cited: 19 times

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Effects of ovariectomy and exercise training intensity on energy substrate and hepatic lipid metabolism, and spontaneous physical activity in mice.

Marc A Tuazon, Sara C Campbell, Dylan J Klein, Sue A Shapses, Keith R Anacker, Tracy G Anthony, Mehmet Uzumcu, Gregory C Henderson,

BACKGROUND:Menopause is associated with fatty liver, glucose dysregulation, increased body fat, and impaired bone quality. Previously, it was demonstrated that single sessions of high-intensity interval exercise (HIIE) are more effective than distance- and duration-matched continuous exercise (CE) on altering hepatic triglyceride (TG) metabolism and very-low density lipoprotein-TG (VLDL-TG) secretion. METHODS:Six ... Read more >>

Metabolism (Metabolism: clinical and experimental)
[2018, 83:234-244]

Cited: 6 times

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Effect of alternate day fasting on markers of bone metabolism: An exploratory analysis of a 6-month randomized controlled trial.

Adrienne Barnosky, Cynthia M Kroeger, John F Trepanowski, Monica C Klempel, Surabhi Bhutani, Kristin K Hoddy, Kelsey Gabel, Sue A Shapses, Krista A Varady,

BACKGROUND:Alternate day fasting (ADF) is a novel diet therapy that reduces body weight, but its effect on bone health remains unknown. OBJECTIVE:This study examined the impact of ADF versus traditional daily calorie restriction (CR) on markers of bone metabolism in a 6-month randomized controlled trial. METHODS:Overweight and obese subjects (n = 100) ... Read more >>

Nutr Healthy Aging (Nutrition and healthy aging)
[2017, 4(3):255-263]

Cited: 7 times

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Change in Bone Mineral Density During Weight Loss with Resistance Versus Aerobic Exercise Training in Older Adults.

Kristen M Beavers, Daniel P Beavers, Sarah B Martin, Anthony P Marsh, Mary F Lyles, Leon Lenchik, Sue A Shapses, Barbara J Nicklas,

<h4>Background</h4>To examine the effect of exercise modality during weight loss on hip and spine bone mineral density (BMD) in overweight and obese, older adults.<h4>Methods</h4>This analysis compared data from two 5-month, randomized controlled trials of caloric restriction (CR; inducing 5-10% weight loss) with either resistance training (RT) or aerobic training (AT) ... Read more >>

J Gerontol A Biol Sci Med Sci (The journals of gerontology. Series A, Biological sciences and medical sciences)
[2017, 72(11):1582-1585]

Cited: 13 times

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Appetite and Gut Hormones Response to a Putative α-Glucosidase Inhibitor, Salacia Chinensis, in Overweight/Obese Adults: A Double Blind Randomized Controlled Trial.

Lihong Hao, Yvette Schlussel, Krista Fieselmann, Stephen H Schneider, Sue A Shapses,

Animal studies indicate <i>Salacia</i> reduces body weight, possibly due to its α-glucosidase inhibitor (α-GI) properties, but this has not been examined previously. In this study, a randomized, placebo-controlled, three-way cross-over design was used to evaluate whether <i>Salacia Chinensis</i> (SC) reduces appetite in healthy overweight/obese individuals (body mass index 28.8 ±3.6 ... Read more >>

Nutrients (Nutrients)
[2017, 9(8):]

Cited: 3 times

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Dietary protein and bone health: a systematic review and meta-analysis from the National Osteoporosis Foundation.

Marissa M Shams-White, Mei Chung, Mengxi Du, Zhuxuan Fu, Karl L Insogna, Micaela C Karlsen, Meryl S LeBoff, Sue A Shapses, Joachim Sackey, Taylor C Wallace, Connie M Weaver,

<b>Background</b>: Considerable attention has recently focused on dietary protein's role in the mature skeleton, prompted partly by an interest in nonpharmacologic approaches to maintain skeletal health in adult life.<b>Objective:</b> The aim was to conduct a systematic review and meta-analysis evaluating the effects of dietary protein intake alone and with calcium ... Read more >>

Am J Clin Nutr (The American journal of clinical nutrition)
[2017, 105(6):1528-1543]

Cited: 58 times

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Obesity is a concern for bone health with aging.

Sue A Shapses, L Claudia Pop, Yang Wang,

Accumulating evidence supports a complex relationship between adiposity and osteoporosis in overweight/obese individuals, with local interactions and endocrine regulation by adipose tissue on bone metabolism and fracture risk in elderly populations. This review was conducted to summarize existing evidence to test the hypothesis that obesity is a risk factor for ... Read more >>

Nutr Res (Nutrition research (New York, N.Y.))
[2017, 39:1-13]

Cited: 30 times

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FREE AND BIOAVAILABLE 25-HYDROXYVITAMIN D LEVELS IN PATIENTS WITH PRIMARY HYPERPARATHYROIDISM.

Xiangbing Wang, Sue A Shapses, Haidar Al-Hraishawi,

<h4>Objective</h4>To evaluate free and bioavailable 25-hydroxyvitamin D (25[OH]D) levels in primary hyperparathyroidism (PHPT) patients.<h4>Methods</h4>Fifty PHPT patients and 50 healthy age-, gender-, and body mass index (BMI)-matched control subjects were enrolled. Levels of 25(OH)D were determined by a radioimmunoassay and vitamin D-binding protein (DBP) were determined by an enzyme-linked immunosorbent assay. ... Read more >>

Endocr Pract (Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists)
[2017, 23(1):66-71]

Cited: 14 times

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