Full Text Journal Articles by
Author Stephen J LeBlanc

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The effect of pegbovigrastim on early-lactation disease, production, and reproduction in dairy cows.

Sabrina J Van Schyndel, Jocelyn Dubuc, Osvaldo Bogado Pascottini, Jérôme Carrier, David F Kelton, Todd F Duffield, Stephen J LeBlanc,

The objective of this randomized, double-blind, controlled trial was to evaluate the effect of pegbovigrastim (pegylated recombinant bovine granulocyte colony-stimulating factor) on early-lactation disease, milk yield, and reproduction on commercial dairy farms. A total of 1,607 Holstein cows from 6 farms in Ontario and Québec, Canada, were randomly assigned to ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, :]

Cited: 0 times

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A Focus Group Study of Canadian Dairy Farmers' Attitudes and Social Referents on Antimicrobial Use and Antimicrobial Resistance.

Claudia Cobo-Angel, Stephen J LeBlanc, Steven M Roche, Caroline Ritter,

As part of broader actions to combat antimicrobial resistance (AMR), health authorities have promoted the reduction of antimicrobial use (AMU) in food animals. Farmers' attitudes and receptivity to reduction of AMU appear to be variable and context specific. Our research objectives were to gain insight into Canadian dairy farmers' attitudes ... Read more >>

Front Vet Sci (Frontiers in veterinary science)
[2021, 8:645221]

Cited: 0 times

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Controlled trial of the effect of negative dietary cation-anion difference prepartum diets on milk production, reproductive performance, and culling of dairy cows.

Rita Couto Serrenho, Tony C Bruinjé, Emma I Morrison, Trevor J DeVries, Todd F Duffield, Stephen J LeBlanc,

Our objective was to assess the effects of feeding negative dietary cation-anion difference (DCAD) prepartum diets on milk production, reproductive performance, and culling. Cows from 4 commercial farms in Ontario, Canada were enrolled in a pen-level controlled trial from November 2017 to April 2019. Close-up pens (1 per farm) with ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, 104(6):6919-6928]

Cited: 0 times

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Controlled trial of the effect of negative dietary cation-anion difference on postpartum health of dairy cows.

Rita Couto Serrenho, Tony C Bruinjé, Emma I Morrison, Trevor J DeVries, Todd F Duffield, Stephen J LeBlanc,

The objective of this study was to assess the effects of feeding negative dietary cation-anion difference (DCAD) dry cow diets on postpartum health. Cows from 4 commercial dairy farms in Ontario, Canada, were enrolled in a pen-level controlled trial from November 2017 to April 2019. Close-up pens (1 per farm), ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, 104(6):6929-6943]

Cited: 0 times

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Graduate Student Literature Review: What do we know about the effects of clinical and subclinical hypocalcemia on health and performance of dairy cows?

Rita Couto Serrenho, Trevor J DeVries, Todd F Duffield, Stephen J LeBlanc,

This narrative literature review summarizes findings regarding the associations of clinical and subclinical hypocalcemia with postpartum health, reproduction, and milk production. To better understand the effects of hypocalcemia, we reviewed clinical and subclinical presentations of the condition and the dynamics of blood Ca concentration in the early postpartum period. We ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, 104(5):6304-6326]

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The effect of prepartum negative dietary cation-anion difference and serum calcium concentration on blood neutrophil function in the transition period of healthy dairy cows.

Rita Couto Serrenho, Emma I Morrison, Osvaldo Bogado Pascottini, Trevor J DeVries, Todd F Duffield, Stephen J LeBlanc,

Our objectives were to assess the effects of a diet with a negative dietary cation-anion difference (DCAD) before calving on phagocytosis (Pc) and oxidative burst (OB) function of circulating neutrophils, and to determine the associations of serum ionized (iCa) and total calcium (tCa) concentrations with Pc and OB in transition ... Read more >>

J Dairy Sci (Journal of dairy science)
[2020, 103(7):6200-6208]

Cited: 0 times

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Modulation of immune function in the bovine uterus peripartum.

Osvaldo Bogado Pascottini, Stephen J LeBlanc,

There is a high risk of clinical or subclinical reproductive tract disease in the postpartum period in dairy cows. An integrated process of adaptive events should occur synchronously, including a robust but well-regulated immune response in the uterus. Failure of this process may result in reproductive tract inflammatory disease. Up ... Read more >>

Theriogenology (Theriogenology)
[2020, 150:193-200]

Cited: 7 times

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Invited review: Completeness of reporting of experiments: REFLECTing on a year of animal trials in the Journal of Dairy Science.

Charlotte B Winder, Katheryn J Churchill, Jan M Sargeant, Stephen J LeBlanc, Annette M O'Connor, David L Renaud,

Reproducibility is an essential element of the scientific process, and it requires clear and complete reporting of study design, conduct, and analysis. In the human and animal health literature, incomplete reporting is associated with biased effect estimates. Moreover, incomplete reporting precludes knowledge synthesis and undervalues the resources allocated to the ... Read more >>

J Dairy Sci (Journal of dairy science)
[2019, 102(6):4759-4771]

Cited: 0 times

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The impact of ecbolic therapy in the early postpartum period on uterine involution and reproductive health in dairy cows.

Cyril P Stephen, Walter H Johnson, Stephen J Leblanc, Robert A Foster, Tracey S Chenier,

Postpartum uterine disease due to poor uterine involution continues to be a significant factor that contributes to poor reproductive efficiency in dairy cattle. Therapy that increases the frequency, duration and strength of uterine contractions in the postpartum period might enhance uterine involution, resulting in improved reproductive performance. The objective of ... Read more >>

J Vet Med Sci (The Journal of veterinary medical science)
[2019, 81(3):491-498]

Cited: 2 times

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Pilot Study to Evaluate the Association Between the Length of the Luteal Phase and Estrous Activity Detected by Automated Activity Monitoring in Dairy Cows.

Jose Denis-Robichaud, Stephen J LeBlanc, Andria Jones-Bitton, Bruna F Silper, Ronaldo L Aoki Cerri,

The ability of automated activity monitoring (AAM) systems to detect estrus is influenced by multiple variables. The luteal phase (LP) preceding estrus has been shown to be important for hormones release, and behavior during estrus in ruminants, but its impact on activity as measured by AAM systems has not been ... Read more >>

Front Vet Sci (Frontiers in veterinary science)
[2018, 5:210]

Cited: 1 time

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Short communication: The effect of calcium supplementation at calving on neutrophil function.

Cynthia L Miltenburg, Todd F Duffield, Dorothee Bienzle, Elizabeth L Scholtz, Stephen J LeBlanc,

Low total blood calcium concentration after calving has been demonstrated to be a risk factor for reduced neutrophil function. The objective of this study was to evaluate whether administration of an injectable calcium supplement product soon after calving increased neutrophil oxidative burst or phagocytosis capacity. Cows (n = 27) from ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(10):9505-9509]

Cited: 0 times

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The effect of pegbovigrastim on circulating neutrophil count in dairy cattle: A randomized controlled trial.

Sabrina J Van Schyndel, Jérôme Carrier, Osvaldo Bogado Pascottini, Stephen J LeBlanc,

Previous research in various species has shown that granulocyte-colony stimulating factor stimulates the production and release of neutrophils from bone marrow. The objective of this study was to characterize the effects of polyethylene glycol-bound bovine granulocyte colony-stimulating factor (pegbovigrastim; Imrestor, Elanco) on circulating leukocyte counts. Thirty-four Holstein cows were randomly ... Read more >>

PLoS One (PloS one)
[2018, 13(6):e0198701]

Cited: 5 times

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Effect of age of introduction to an automated milk feeder on calf learning and performance and labor requirements.

Catalina Medrano-Galarza, Stephen J LeBlanc, Trevor J DeVries, Andria Jones-Bitton, Jeffrey Rushen, Anne Marie de Passillé, Marcia I Endres, Derek B Haley,

Group housing of dairy calves with automated milk feeders (AMF) is increasingly being used, but the effect of introducing calves to the AMF at a very young age (<24 h) on calf performance, health, and welfare, as well as farm personnel labor requirements are unknown. The objective of this controlled ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(10):9371-9384]

Cited: 0 times

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Cost of retained fetal membranes for dairy herds in the United States.

Khaled Gohary, Stephen J LeBlanc,

OBJECTIVE To estimate the cost of a case of retained fetal membranes (RFM) for dairy herds in the United States. DESIGN Deterministic computer-based spreadsheet analysis. SAMPLE Inputs from published studies and reports. PROCEDURES Economic losses attributable to RFM were direct (reduction in milk yield and longer interval until pregnancy) and ... Read more >>

J Am Vet Med Assoc (Journal of the American Veterinary Medical Association)
[2018, 252(12):1485-1489]

Cited: 0 times

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The effect of prepartum feeding and lying space on metabolic health and immune function.

Cynthia L Miltenburg, Todd F Duffield, Dorothee Bienzle, Elizabeth L Scholtz, Stephen J LeBlanc,

The determinants of metabolic and reproductive health disorders in the peripartum period and the degree to which feeding and lying space and management can influence health are only partially understood. The objective of this randomized controlled study was to determine whether providing noncompetitive feeding and lying access in the close-up ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(6):5294-5306]

Cited: 4 times

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Effects of local anesthetic or systemic analgesia on pain associated with cautery disbudding in calves: A systematic review and meta-analysis.

Charlotte B Winder, Cynthia L Miltenburg, Jan M Sargeant, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

Disbudding is a common management procedure performed on dairy farms and, when done without pain mitigation, is viewed as a key welfare issue. Use of pain control has increased in recent years, but full adoption of anesthesia and analgesia by veterinarians or dairy producers has not been achieved. This may ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(6):5411-5427]

Cited: 8 times

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Effect of stall design on dairy calf transition to voluntary feeding on an automatic milk feeder after introduction to group housing.

Tanya R Wilson, Stephen J LeBlanc, Trevor J DeVries, Derek B Haley,

Automatic milk feeders (AMF) for young dairy calves are widely used in the dairy industry. These feeders are thought to have benefits for calf health and welfare and may reduce labor required for feeding; however, little is known about how calves adapt to feeding with AMF. The objective of this ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(6):5307-5316]

Cited: 0 times

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Cow- and herd-level factors associated with lameness in small-scale grazing dairy herds in Brazil.

José A Bran, Rolnei R Daros, Marina A G von Keyserlingk, Stephen J LeBlanc, Maria José Hötzel,

This cross-sectional study aimed to assess lameness occurrence and to identify the associated risk factors in small-scale grazing dairy herds. Forty four farms (mean lactating herd size was 42 cows, SD = 11.2, range: 28-74) located in the south of Brazil were visited twice, approximately 4 months apart, in 2015. Locomotion was ... Read more >>

Prev Vet Med (Preventive veterinary medicine)
[2018, 151:79-86]

Cited: 6 times

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Associations between management practices and within-pen prevalence of calf diarrhea and respiratory disease on dairy farms using automated milk feeders.

Catalina Medrano-Galarza, Stephen J LeBlanc, Andria Jones-Bitton, Trevor J DeVries, Jeffrey Rushen, Anne Marie de Passillé, Marcia I Endres, Derek B Haley,

Data on management practices used with automated milk feeders (AMF) are needed to identify factors associated with calf health in these systems. The objectives of this observational, longitudinal, cross-sectional study were to estimate the prevalence of calf diarrhea (CD) and bovine respiratory disease (BRD), and to identify factors associated with ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(3):2293-2308]

Cited: 7 times

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Corrigendum to "A survey of dairy calf management practices among farms using manual and automated milk feeding systems in Canada" (J. Dairy Sci. 100:6872-6884).

Catalina Medrano-Galarza, Stephen J LeBlanc, Trevor J DeVries, Andria Jones-Bitton, Jeffrey Rushen, Anne Marie de Passillé, Derek B Haley,

J Dairy Sci (Journal of dairy science)
[2017, 100(11):9477]

Cited: 0 times

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Comparison of online, hands-on, and a combined approach for teaching cautery disbudding technique to dairy producers.

Charlotte B Winder, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

The use of pain control for disbudding and dehorning is important from both an animal and industry perspective. Best practices include the use of local anesthetic, commonly given as a cornual nerve block (CNB), and a nonsteroidal anti-inflammatory drug. The proportion is decreasing, but many dairy producers do not use ... Read more >>

J Dairy Sci (Journal of dairy science)
[2018, 101(1):840-849]

Cited: 2 times

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Clinical trial of local anesthetic protocols for acute pain associated with caustic paste disbudding in dairy calves.

Charlotte B Winder, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

Caustic paste disbudding is becoming more commonplace in North America. A large body of work has examined pain control for cautery disbudding and surgical dehorning, but fewer studies have evaluated pain control for caustic paste disbudding, and results conflict regarding benefits of local anesthesia. In humans, the pain associated with ... Read more >>

J Dairy Sci (Journal of dairy science)
[2017, 100(8):6429-6441]

Cited: 6 times

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Comparison of an online learning module to hands-on training in teaching a cautery disbudding technique for dairy calves including cornual nerve block application.

Charlotte B Winder, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield,

Disbudding and dehorning are common procedures on dairy farms. In a recent survey of Ontario dairy producers, 38% reported not using local anesthetic for these procedures. Use of pain control is important for both calf welfare and industry sustainability. Use of local anesthetic requires technical training, typically provided by a ... Read more >>

Can Vet J (The Canadian veterinary journal = La revue veterinaire canadienne)
[2017, 58(7):735-740]

Cited: 3 times

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Prevalence and risk factors for transition period diseases in grazing dairy cows in Brazil.

Rolnei R Daros, Maria J Hötzel, Jose A Bran, Stephen J LeBlanc, Marina A G von Keyserlingk,

The aim of this cross-sectional study was to describe the incidence risk of dystocia, retained placenta (RP), pathological recumbence (down cow), the prevalence of metritis and subclinical ketosis (SCK), and the risk factors for SCK, metritis, and RP in grazing dairy herds in Southern Brazil. Fifty-three herds were visited 2-6 ... Read more >>

Prev Vet Med (Preventive veterinary medicine)
[2017, 145:16-22]

Cited: 4 times

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A survey of dairy calf management practices among farms using manual and automated milk feeding systems in Canada.

Catalina Medrano-Galarza, Stephen J LeBlanc, Trevor J DeVries, Andria Jones-Bitton, Jeffrey Rushen, Anne Marie de Passillé, Derek B Haley,

Dairy calves in North America traditionally are housed individually and fed by manual milk feeding (MMF) systems with buckets or bottles. Automated milk feeders (AMF) allow for more natural milk feeding frequencies and volumes, and calves are usually housed in groups. The objectives of this study were to (1) determine ... Read more >>

J Dairy Sci (Journal of dairy science)
[2017, 100(8):6872-6884]

Cited: 8 times

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