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A Controlled Trial of Rivaroxaban after Transcatheter Aortic-Valve Replacement.

George D Dangas, Jan G P Tijssen, Jochen Wöhrle, Lars Søndergaard, Martine Gilard, Helge Möllmann, Raj R Makkar, Howard C Herrmann, Gennaro Giustino, Stephan Baldus, Ole De Backer, Ana H C Guimarães, Lars Gullestad, Annapoorna Kini, Dirk von Lewinski, Michael Mack, Raúl Moreno, Ulrich Schäfer, Julia Seeger, Didier Tchétché, Karen Thomitzek, Marco Valgimigli, Pascal Vranckx, Robert C Welsh, Peter Wildgoose, Albert A Volkl, Ana Zazula, Ronald G M van Amsterdam, Roxana Mehran, Stephan Windecker, ,

BACKGROUND:Whether the direct factor Xa inhibitor rivaroxaban can prevent thromboembolic events after transcatheter aortic-valve replacement (TAVR) is unclear. METHODS:We randomly assigned 1644 patients without an established indication for oral anticoagulation after successful TAVR to receive rivaroxaban at a dose of 10 mg daily (with aspirin at a dose of 75 ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2019, :]

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Reduced Leaflet Motion after Transcatheter Aortic-Valve Replacement.

Ole De Backer, George D Dangas, Hasan Jilaihawi, Jonathon A Leipsic, Christian J Terkelsen, Raj Makkar, Annapoorna S Kini, Karsten T Veien, Mohamed Abdel-Wahab, Won-Keun Kim, Prakash Balan, Nicolas Van Mieghem, Ole N Mathiassen, Raban V Jeger, Martin Arnold, Roxana Mehran, Ana H C Guimarães, Bjarne L Nørgaard, Klaus F Kofoed, Philipp Blanke, Stephan Windecker, Lars Søndergaard, ,

BACKGROUND:Subclinical leaflet thickening and reduced leaflet motion of bioprosthetic aortic valves have been documented by four-dimensional computed tomography (CT). Whether anticoagulation can reduce these phenomena after transcatheter aortic-valve replacement (TAVR) is not known. METHODS:In a substudy of a large randomized trial, we randomly assigned patients who had undergone successful TAVR ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2019, :]

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Ticagrelor Alone Versus Dual Antiplatelet Therapy From 1 Month After Drug-Eluting Coronary Stenting.

Anna Franzone, Eugène McFadden, Sergio Leonardi, Raffaele Piccolo, Pascal Vranckx, Patrick W Serruys, Edouard Benit, Christoph Liebetrau, Luc Janssens, Maurizio Ferrario, Aleksander Zurakowski, Roberto Diletti, Marcello Dominici, Kurt Huber, Ton Slagboom, Paweł Buszman, Leonardo Bolognese, Carlo Tumscitz, Krzysztof Bryniarski, Adel Aminian, Mathias Vrolix, Ivo Petrov, Scot Garg, Christoph Naber, Janusz Prokopczuk, Christian Hamm, Philippe Gabriel Steg, Dik Heg, Peter Jüni, Stephan Windecker, Marco Valgimigli, ,

BACKGROUND:The GLOBAL LEADERS (GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation) study randomly assigned 15,991 patients undergoing percutaneous coronary intervention to 1-month dual antiplatelet therapy (DAPT) followed by 23-month ticagrelor monotherapy or conventional 12-month DAPT followed by 12-month aspirin. Apart from Q-wave myocardial infarction ... Read more >>

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, 74(18):2223-2234]

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Stent Thrombosis in Patients with Atrial Fibrillation Undergoing Coronary Stenting in the AUGUSTUS Trial.

Renato D Lopes, Sergio Leonardi, Daniel M Wojdyla, Amit N Vora, Laine Thomas, Robert F Storey, Dragos Vinereanu, Christopher B Granger, Shaun G Goodman, Ronald Aronson, Stephan Windecker, Holger Thiele, Marco Valgimigli, Roxana Mehran, John H Alexander,

We describe the incidence, timing, and characteristics of stent thrombosis and its consequences in patients with atrial fibrillation (AF) in the AUGUSTUS trial1 who received a coronary stent during their qualifying admission (acute coronary syndrome [ACS] or elective percutaneous coronary intervention [PCI]) and the randomized treatment effects of low-dose aspirin ... Read more >>

Circulation (Circulation)
[2019, :]

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Diabetes and baseline glucose are associated with inflammation, left ventricular function and short- and long-term outcome in acute coronary syndromes: role of the novel biomarker Cyr 61.

Patric Winzap, Allan Davies, Roland Klingenberg, Slayman Obeid, Marco Roffi, François Mach, Lorenz Räber, Stephan Windecker, Christian Templin, Fabian Nietlispach, David Nanchen, Baris Gencer, Olivier Muller, Christian M Matter, Arnold von Eckardstein, Thomas F Lüscher,

BACKGROUND:Hyperglycemia in the setting of an acute coronary syndrome (ACS) impacts short term outcomes, but little is known about longer term effects. We therefore designed this study to firstly determine the association between hyperglycemia and short term and longer term outcomes in patients presenting with ACS and secondly evaluate the ... Read more >>

Cardiovasc Diabetol (Cardiovascular diabetology)
[2019, 18(1):142]

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Five-Year Outcomes in Patients With Diabetes Mellitus Treated With Biodegradable Polymer Sirolimus-Eluting Stents Versus Durable Polymer Everolimus-Eluting Stents.

Juan F Iglesias, Dik Heg, Marco Roffi, David Tüller, Jonas Lanz, Fabio Rigamonti, Olivier Muller, Igal Moarof, Stéphane Cook, Daniel Weilenmann, Christoph Kaiser, Florim Cuculi, Marco Valgimigli, Peter Jüni, Stephan Windecker, Thomas Pilgrim,

Background The choice of optimal drug-eluting stent therapy for patients with diabetes mellitus (DM) undergoing percutaneous coronary intervention remains uncertain. We aimed to assess the long-term clinical outcomes after percutaneous coronary intervention with biodegradable polymer sirolimus-eluting stents (BP-SES) versus durable polymer everolimus-eluting stents (DP-EES) in patients with DM. Methods and ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2019, 8(22):e013607]

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Association of Sex With Outcomes in Patients Undergoing Percutaneous Coronary Intervention: A Subgroup Analysis of the GLOBAL LEADERS Randomized Clinical Trial.

Ply Chichareon, Rodrigo Modolo, Laura Kerkmeijer, Mariusz Tomaniak, Norihiro Kogame, Kuniaki Takahashi, Chun-Chin Chang, Hidenori Komiyama, Tiziano Moccetti, Suneel Talwar, Antonio Colombo, Luc Maillard, Peter Barlis, Joanna Wykrzykowska, Jan J Piek, Scot Garg, Christian Hamm, Philippe Gabriel Steg, Peter Jüni, Marco Valgimigli, Stephan Windecker, Yoshinobu Onuma, Roxana Mehran, Patrick W Serruys,

Importance:Women experience worse ischemic and bleeding outcomes after percutaneous coronary intervention (PCI). Objectives:To assess the association of sex with patient outcomes at 2 years after contemporary PCI and with the efficacy and safety of 2 antiplatelet strategies. Design, Setting, and Analysis:This study is a prespecified subgroup analysis of the investigator-initiated, ... Read more >>

JAMA Cardiol (JAMA cardiology)
[2019, :1-10]

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Comparison of clinical outcomes between Magmaris and Orsiro drug eluting stent at 12 months: Pooled patient level analysis from BIOSOLVE II-III and BIOFLOW II trials.

Alexandre Hideo-Kajita, Hector M Garcia-Garcia, Paul Kolm, Viana Azizi, Yuichi Ozaki, Kazuhiro Dan, Hüseyin Ince, Stephan Kische, Alexandre Abizaid, Ralph Töelg, Pedro Alves Lemos, Nicolas M Van Mieghem, Stefan Verheye, Clemens von Birgelen, Evald Høj Christiansen, William Wijns, Thierry Lefèvre, Stephan Windecker, Ron Waksman, Michael Haude, ,

BACKGROUND:The aim of this study was to compare the 12-month clinical outcomes of patients treated with Magmaris or Orsiro. Second generation drug-eluting absorbable metal scaffold Magmaris (Dreams 2G) has proved to be safe and effective in the BIOSOLVE-II study. Similarly, biodegradable polymer sirolimus-eluting stent, Orsiro has shown notable clinical results ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2019, :]

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Reply: SYNERGY Early Stent Thrombosis.

Christian Zanchin, Yasushi Ueki, Stephan Windecker, Lorenz Räber,

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2019, 12(21):2228]

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Initial European experience with transcaval transcatheter aortic valve implantation.

Giulia Costa, Ole De Backer, Thomas Pilgrim, Markus Kasel, Simon Redwood, Adel Aminian, Jonas Lanz, Jonathan Michel, Tiffany Patterson, Stephan Windecker, Bernard Prendergast, Adam B Greenbaum, Lars Søndergaard,

AIMS:A transfemoral transarterial approach is considered the preferable access route for transcatheter aortic valve implantation (TAVI), followed by a transaxillary/subclavian TAVI approach. However, these approaches may not be an option in all patients. This study aimed to report the initial European experience with transfemoral transcaval TAVI. METHODS AND RESULTS:Data on ... Read more >>

EuroIntervention (EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology)
[2019, :]

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Long-term clinical outcomes of Amplatzer cardiac plug versus Amulet occluders for left atrial appendage closure.

Caroline Kleinecke, Mohammad Cheikh-Ibrahim, Steffen Schnupp, Mate Fankhauser, Fabian Nietlispach, Jai-Wun Park, Johannes Brachmann, Stephan Windecker, Bernhard Meier, Steffen Gloekler,

OBJECTIVES:To compare long-term clinical outcomes after left atrial appendage closure with the Amplatzer Cardiac Plug (ACP) and Amulet. BACKGROUND:The Amulet was designed to improve clinical outcomes of first-generation ACP. METHODS:Three Amplatzer registries (Bern, Coburg, Zurich), with enrollment of patients from 2009 to 2018, were retrospectively analyzed. The primary safety endpoint ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2019, :]

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Control of cardiovascular risk factors and health behaviors in patients post acute coronary syndromes eligible for protein convertase subtilisin/kexin-9 inhibitors.

Audrey Butty, Baris Gencer, Konstantinos C Koskinas, David Carballo, Lorenz Räber, Roland Klingenberg, Christian M Matter, Thomas F Lüscher, Stephan Windecker, Olivier Muller, Nicolas Rodondi, François Mach, David Nanchen,

BACKGROUND:We aimed to examine cardiovascular risk factors and health behaviors in patients with acute coronary syndromes (ACS) according to potential extension of eligibility criteria for protein convertase subtilisin/kexin-9 inhibitors (PCSK9i) to all patients with low-density lipoprotein cholesterol (LDL-c) equal or above 1.8 mmol/l. METHODS:In this prospective cross-sectional study, patients with ACS ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2019, :]

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Efficacy and Safety of Ticagrelor Monotherapy in Patients Undergoing Multivessel PCI.

Kuniaki Takahashi, Patrick W Serruys, Ply Chichareon, Chun Chin Chang, Mariusz Tomaniak, Rodrigo Modolo, Norihiro Kogame, Michael Magro, Saqib Chowdhary, Ingo Eitel, Robert Zweiker, Paul Ong, Michael Mundt Ottesen, Jan G P Tijssen, Joanna J Wykrzykowska, Robbert J de Winter, Scot Garg, Hans-Peter Stoll, Christian Hamm, Philippe Gabriel Steg, Yoshinobu Onuma, Marco Valgimigli, Pascal Vranckx, Didier Carrie, Stephan Windecker,

BACKGROUND:Data on optimal antiplatelet treatment regimens in patients who undergo multivessel percutaneous coronary intervention (PCI) are sparse. OBJECTIVES:This post hoc study investigated the impact of an experimental strategy (1-month dual antiplatelet therapy [DAPT] followed by 23-month ticagrelor monotherapy) versus a reference regimen (12-month DAPT followed by 12-month aspirin monotherapy) according ... Read more >>

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, 74(16):2015-2027]

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Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of symptomatic severe aortic stenosis: an updated meta-analysis.

George C M Siontis, Pavel Overtchouk, Thomas J Cahill, Thomas Modine, Bernard Prendergast, Fabien Praz, Thomas Pilgrim, Tatjana Petrinic, Adriani Nikolakopoulou, Georgia Salanti, Lars Søndergaard, Subodh Verma, Peter Jüni, Stephan Windecker,

AIMS :Owing to new evidence from randomized controlled trials (RCTs) in low-risk patients with severe aortic stenosis, we compared the collective safety and efficacy of transcatheter aortic valve implantation (TAVI) vs. surgical aortic valve replacement (SAVR) across the entire spectrum of surgical risk patients. METHODS AND RESULTS :The meta-analysis is registered with ... Read more >>

Eur. Heart J. (European heart journal)
[2019, 40(38):3143-3153]

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Benefit and Risks of Aspirin in Addition to Ticagrelor in Acute Coronary Syndromes: A Post Hoc Analysis of the Randomized GLOBAL LEADERS Trial.

Mariusz Tomaniak, Ply Chichareon, Yoshinobu Onuma, Efthymios N Deliargyris, Kuniaki Takahashi, Norihiro Kogame, Rodrigo Modolo, Chun Ching Chang, Tessa Rademaker-Havinga, Robert F Storey, George D Dangas, Deepak L Bhatt, Dominick J Angiolillo, Christian Hamm, Marco Valgimigli, Stephan Windecker, Philippe Gabriel Steg, Pascal Vranckx, Patrick W Serruys, ,

Importance:The role of aspirin as part of antiplatelet regimens in acute coronary syndromes (ACS) needs to be clarified in the context of newer potent P2Y12 antagonists. Objective:To evaluate the benefit and risks of aspirin in addition to ticagrelor among patients with ACS beyond 1 month after percutaneous coronary intervention (PCI). ... Read more >>

JAMA Cardiol (JAMA cardiology)
[2019, :]

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Antithrombotic Therapy in Patients with Atrial Fibrillation and Acute Coronary Syndrome Treated Medically or with Percutaneous Coronary Intervention or Undergoing Elective Percutaneous Coronary Intervention: Insights from the AUGUSTUS Trial.

Stephan Windecker, Renato D Lopes, Tyler Massaro, Charlotte Jones-Burton, Christopher B Granger, Ronald Aronson, Gretchen Heizer, Shaun G Goodman, Harald Darius, W Schuyler Jones, Michael Aschermann, David Brieger, Fernando Cura, Thomas Engstrøm, Viliam Fridrich, Sigrun Halvorsen, Kurt Huber, Hyun-Jae Kang, Jose L Leiva-Pons, Basil S Lewis, German Malaga, Nicolas Meneveau, Bela Merkely, Davor Milicic, João Morais, Tatjana S Potpara, Dimitar Raev, Manel Sabaté, Suzanne de Waha-Thiele, Robert C Welsh, Denis Xavier, Roxana Mehran, John H Alexander, ,

Background: The safety and efficacy of antithrombotic regimens may differ between patients with atrial fibrillation (AF) who have acute coronary syndromes (ACS), treated medically or with percutaneous coronary intervention (PCI), and those undergoing elective PCI. Methods: Using a 2×2 factorial design we compared apixaban with vitamin K antagonists (VKA) and ... Read more >>

Circulation (Circulation)
[2019, :]

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Hospitalization among Patients with Atrial Fibrillation and a Recent Acute Coronary Syndrome or Percutaneous Coronary Intervention Treated with Apixaban or Aspirin: Insights from the AUGUSTUS Trial.

Amit N Vora, John H Alexander, Daniel Wojdyla, Ronald Aronson, Christopher B Granger, Harald Darius, Stephan Windecker, Roxana Mehran, Oleg Averkov, Andrzej J Budaj, David F Kong, Zhanna Kobalava, Rajendra H Mehta, Zulfiqar Mirza, Patricia Oliveira Guimaraes, Alexander Parkhomenko, Alexandre Quadros, Holger Thiele, Shaun G Goodman, Renato D Lopes,

The optimal antithrombotic therapy among patients with atrial fibrillation (AF) who present with acute coronary syndrome (ACS) or require percutaneous coronary intervention (PCI) can be challenging, with combination therapy including both dual antiplatelet therapy (DAPT) and oral anticoagulation (OAC) markedly increasing bleeding risk.1 Recent trials with rivaroxaban2 and dabigatran3 have ... Read more >>

Circulation (Circulation)
[2019, :]

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Transcatheter versus medical treatment of symptomatic severe tricuspid regurgitation.

Maurizio Taramasso, Giovanni Benfari, Pieter van der Bijl, Hannes Alessandrini, Adrian Attinger-Toller, Luigi Biasco, Philipp Lurz, Daniel Braun, Eric Brochet, Kim A Connelly, Sabine de Bruijn, Paolo Denti, Florian Deuschl, Rodrigo Estevez-Loureiro, Neil Fam, Christian Frerker, Mara Gavazzoni, Jo Rg Hausleiter, Edwin Ho, Jean-Michel Juliard, Ryan Kaple, Christian Besler, Susheel Kodali, Felix Kreidel, Karl-Heinz Kuck, Azeem Latib, Alexander Lauten, Vanessa Monivas, Michael Mehr, Guillem Muntané-Carol, Tamin Nazif, Georg Nickening, Giovanni Pedrazzini, François Philippon, Alberto Pozzoli, Fabien Praz, Rishi Puri, Josep Rodés-Cabau, Ulrich Scha Fer, Joachim Schofer, Horst Sievert, Gilbert H L Tang, Holger Thiele, Yan Topilsky, Karl-Philipp Rommel, Victoria Delgado, Alec Vahanian, Ralph Stephan Von Bardeleben, John G Webb, Marcel Weber, Stephan Windecker, Mirjam Winkel, Michel Zuber, Martin B Leon, Rebecca T Hahn, Jeroen J Bax, Maurice Enriquez-Sarano, Francesco Maisano,

BACKGROUND:Tricuspid Regurgitation (TR) is associated with increased rates of heart failure (HF) and mortality. Transcatheter tricuspid valve interventions (TTVI) are promising, but the clinical benefit is unknown. OBJECTIVES:To investigate the potential benefit of TTVI over medical therapy in a propensity score matched population. METHODS:The TriValve (Transcatheter Tricuspid Valve Therapies) registry ... Read more >>

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, :]

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Prosthesis-Patient Mismatch Following Transcatheter Aortic Valve Replacement With Supra-Annular and Intra-Annular Prostheses.

Taishi Okuno, Faisal Khan, Masahiko Asami, Fabien Praz, Dik Heg, Mirjam Gauri Winkel, Jonas Lanz, Adrian Huber, Christoph Gräni, Lorenz Räber, Stefan Stortecky, Marco Valgimigli, Stephan Windecker, Thomas Pilgrim,

OBJECTIVES:This study sought to compare the frequency of prosthesis-patient mismatch (PPM) with self-expandable valves (SEV) to balloon-expandable valves (BEV). BACKGROUND:PPM has been associated with increased mortality after transcatheter aortic valve replacement. Data on the frequency of PPM as a function of supra-annular or intra-annular position of transcatheter heart valves are ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2019, 12(21):2173-2182]

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Percutaneous Mitral Edge-to-Edge Repair: State of the Art and a Glimpse to the Future.

Faisal Khan, Mirjam Winkel, Geraldine Ong, Nicolas Brugger, Thomas Pilgrim, Stephan Windecker, Fabien Praz, Neil Fam,

Patients with severe symptomatic mitral regurgitation have a poor prognosis if left untreated. In those patients who are not eligible for mitral valve surgery, percutaneous edge-to-edge repair may improve clinical outcomes. Recent clinical trials have added to our knowledge and provide interesting insights into the management of such patients. With ... Read more >>

Front Cardiovasc Med (Frontiers in cardiovascular medicine)
[2019, 6:122]

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Femoral Access With or Without Vascular Closure Device or Radial Access in Acute Coronary Syndrome.

Felice Gragnano, Negar Manavifar, Giuseppe Gargiulo, Mikael Sunnåker, Roberto Galea, Enrico Frigoli, Paolo Calabrò, Stephan Windecker, Marco Valgimigli,

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2019, 12(20):2116-2118]

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Impact of Periprocedural Myocardial Biomarker Elevation on Mortality Following Elective Percutaneous Coronary Intervention.

Hector M Garcia-Garcia, Eugène P McFadden, Clemens von Birgelen, Tessa Rademaker-Havinga, Ernest Spitzer, Neal S Kleiman, David J Cohen, Kevin F Kennedy, Edoardo Camenzind, Laura Mauri, Philippe Gabriel Steg, William Wijns, Sigmund Silber, Gerrit-Anne van Es, Patrick W Serruys, Stephan Windecker, Donald Cutlip, Pascal Vranckx,

OBJECTIVES:This study sought to explore the association between biomarker elevation, with creatine kinase-myocardial band (CK-MB) or cardiac troponin (cTn), following percutaneous coronary intervention (PCI) and mortality in patients undergoing PCI for stable angina with normal baseline values. BACKGROUND:Several studies have shown a strong association between post-PCI CK-MB elevation and subsequent ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2019, 12(19):1954-1962]

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Ascertainment of Silent Myocardial Infarction in Patients Undergoing Percutaneous Coronary Intervention (from the GLOBAL LEADERS Trial).

Chun Chin Chang, Ernest Spitzer, Ply Chichareon, Kuniaki Takahashi, Rodrigo Modolo, Norihiro Kogame, Mariusz Tomaniak, Hidenori Komiyama, Sing-Chien Yap, Stephen P Hoole, Tommaso Gori, Azfar Zaman, Bernhard Frey, Rui Cruz Ferreira, Olivier F Bertrand, Tian Hai Koh, Amanda Sousa, Aris Moschovitis, Robert-Jan van Geuns, Philippe Gabriel Steg, Christian Hamm, Peter Jüni, Pascal Vranckx, Marco Valgimigli, Stephan Windecker, Patrick W Serruys, Osama Soliman, Yoshinobu Onuma,

Q-wave myocardial infarction (QWMI) comprises 2 entities. First, a clinically evident MI, which can occur spontaneously or be related to a coronary procedure. Second, silent MI which is incidentally detected on serial electrocardiographic (ECG) assessment. The prevalence of silent MI after percutaneous coronary intervention (PCI) in the drug-eluting stent era ... Read more >>

Am. J. Cardiol. (The American journal of cardiology)
[2019, :]

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Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement in patients with symptomatic severe aortic stenosis: a randomised non-inferiority trial.

Jonas Lanz, Won-Keun Kim, Thomas Walther, Christof Burgdorf, Helge Möllmann, Axel Linke, Simon Redwood, Christian Thilo, Michael Hilker, Michael Joner, Holger Thiele, Lars Conzelmann, Lenard Conradi, Sebastian Kerber, Gerhard Schymik, Bernard Prendergast, Oliver Husser, Stefan Stortecky, Dik Heg, Peter Jüni, Stephan Windecker, Thomas Pilgrim, ,

BACKGROUND:Transcatheter aortic valve replacement (TAVR) is the preferred treatment option for older patients with symptomatic severe aortic stenosis. Differences in the properties of available TAVR systems can affect clinical outcomes. Among patients undergoing TAVR, we compared the self-expanding ACURATE neo TAVR system with the balloon-expandable SAPIEN 3 TAVR system with ... Read more >>

Lancet (Lancet (London, England))
[2019, 394(10209):1619-1628]

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Contemporary Presentation and Management of Valvular Heart Disease: The EURObservational Research Programme Valvular Heart Disease II Survey.

Bernard Iung, Victoria Delgado, Raphael Rosenhek, Susanna Price, Bernard Prendergast, Olaf Wendler, Michele De Bonis, Christophe Tribouilloy, Arturo Evangelista, Alexander Bogachev-Prokophiev, Astrid Apor, Hüseyin Ince, Cécile Laroche, Bogdan A Popescu, Luc Piérard, Michael Haude, Gerhard Hindricks, Frank Ruschitzka, Stephan Windecker, Jeroen J Bax, Aldo Maggioni, Alec Vahanian, ,

Background: Valvular heart disease (VHD) is an important cause of mortality and morbidity and has been subject to important changes in management. The VHD II survey was designed by the EURObservational Research Programme of the European Society of Cardiology (ESC) to analyze actual management of VHD and compare practice with ... Read more >>

Circulation (Circulation)
[2019, :]

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