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Author Stefano Uccella

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Author's reply to: Comments on the utilization of Mann-Whitney U test and Kaplan-Meier method.

Marcello Ceccaroni, Giovanni Roviglione, Simone Garzon, Francesco Bruni, Stefano Uccella,

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(3):e54]

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Asherman's Syndrome after Uterine Artery Embolization. A case of embolic spheres displacement inside the uterine cavity.

Giampietro Gubbini, Giulia Bertapelle, Mariachiara Bosco, Pier Carlo Zorzato, Stefano Uccella, Alessandro Favilli,

J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2021, :]

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OHIA syndrome: Stop before it is too late!

Alessandro Favilli, Ivan Mazzon, Pier Carlo Zorzato, Stefano Uccella, Sandro Gerli,

Taiwan J Obstet Gynecol (Taiwanese journal of obstetrics & gynecology)
[2021, 60(2):385-386]

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Regarding "Trends and Risk Factors for Vaginal Cuff Dehiscence after Laparoscopic Hysterectomy".

Stefano Uccella, Pier Carlo Zorzato, Alessandro Favilli, Mariachiara Bosco, Massimo P Franchi, Simone Garzon,

J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2021, 28(4):913]

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Incidence and Prevention of Vaginal Cuff Dehiscence after Laparoscopic and Robotic Hysterectomy: A Systematic Review and Meta-analysis.

Stefano Uccella, Pier Carlo Zorzato, Rosanne M Kho,

<h4>Objective</h4>Vaginal cuff dehiscence, a severe and potentially detrimental complication, has significantly increased after the introduction of endoscopic hysterectomy. The aim of this systematic review and meta-analysis of the available literature was to identify the incidence of, and possible strategies to prevent, this complication after total laparoscopic hysterectomy and total robotic ... Read more >>

J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2021, 28(3):710-720]

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Aromatase inhibitors for the treatment of endometriosis: a systematic review about efficacy, safety and early clinical development.

Simone Garzon, Antonio Simone Laganà, Fabio Barra, Jvan Casarin, Antonella Cromi, Ricciarda Raffaelli, Stefano Uccella, Massimo Franchi, Fabio Ghezzi, Simone Ferrero,

<h4>Introduction</h4>Pharmacotherapy has a key role in endometriosis treatment and management, however, a significant proportion of patients have only intermittent or limited benefits with current treatment options. Therefore, novel therapeutic approaches are necessary.<h4>Areas covered</h4>This systematic review provides an overview of the efficacy and safety of aromatase inhibitors (AIs) as monotherapies and ... Read more >>

Expert Opin Investig Drugs (Expert opinion on investigational drugs)
[2020, 29(12):1377-1388]

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Total laparoscopic vs. conventional open abdominal nerve-sparing radical hysterectomy: clinical, surgical, oncological and functional outcomes in 301 patients with cervical cancer.

Marcello Ceccaroni, Giovanni Roviglione, Mario Malzoni, Francesco Cosentino, Emanuela Spagnolo, Roberto Clarizia, Paolo Casadio, Renato Seracchioli, Fabio Ghezzi, Daniele Mautone, Francesco Bruni, Stefano Uccella,

<h4>Objective</h4>Total laparoscopic nerve-sparing radical hysterectomy (TL-NSRH) has been considered a promising approach, however, surgical, clinical, oncological and functional outcomes have not been systematically addressed. We present a large retrospective multi-center experience comparing TL-NSRH vs. open abdominal NSRH (OA-NSRH) for early and locally-advanced cervical cancer, with particular emphasis on post-surgical pelvic ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(1):e10]

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Fertility-sparing management for endometrial cancer: review of the literature.

Simone Garzon, Stefano Uccella, Pier Carlo Zorzato, Mariachiara Bosco, Massimo P Franchi, Vladimir Student, Andrea Mariani,

<h4>Introduction</h4>Primary surgery is effective in low-risk endometrial cancer (EC). However, in young women, this approach compromises fertility. Therefore, fertility-sparing management in the case of atypical endometrial hyperplasia, or grade 1 EC limited to the endometrium can be considered.<h4>Evidence acquisition</h4>We performed a literature review to identify studies involving women with EC ... Read more >>

Minerva Med (Minerva medica)
[2021, 112(1):55-69]

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Sentinel lymph node for endometrial cancer treatment: review of the literature.

Pier C Zorzato, Mariachiara Bosco, Massimo P Franchi, Andrea Mariani, Stefano Cianci, Simone Garzon, Stefano Uccella,

<h4>Introduction</h4>Endometrial cancer is the most common gynecologic malignancy and in two thirds of patients it is apparently uterine confined at presentation. Lymph nodal status represents one of the main prognostic factors. Nodal evaluation with sentinel lymph node (SLN) mapping has gained more ground in clinical practice after the publication of ... Read more >>

Minerva Med (Minerva medica)
[2021, 112(1):70-80]

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Uterine manipulator in endometrial cancer: we are still far from the answer.

Stefano Uccella, Stefano Cianci, Salvatore Gueli Alletti,

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2021, 224(3):332]

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Novel drug delivery methods for improving efficacy of endometriosis treatments.

Simone Garzon, Antonio Simone Laganà, Fabio Barra, Jvan Casarin, Antonella Cromi, Ricciarda Raffaelli, Stefano Uccella, Massimo Franchi, Fabio Ghezzi, Simone Ferrero,

<h4>Introduction</h4>Pharmacotherapy has a key role in the management of endometriosis. However, a significant proportion of patients gains only intermittent or limited benefits. In this regard, alternative and novel drug delivery methods are of paramount importance to improve efficacy and compliance of available treatments and develop alternative medical approaches.<h4>Areas covered</h4>This review ... Read more >>

Expert Opin Drug Deliv (Expert opinion on drug delivery)
[2020, :1-13]

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Quality of life and sexual functioning of patient affected by endometrial cancer.

Stefano Cianci, Andrea Rosati, Vito A Capozzi, Mattia Tarascio, Stefano Uccella, Marco Palumbo, Salvatore Caruso,

<h4>Introduction</h4>Thanks to timely diagnosis and medical advancement the number of endometrial cancer (EC) patients achieving long term survival is constantly increasing and here comes the necessity to move forward with the understanding of post-treatment sexual adjustment and with the strategies to enhance sexual functioning (SF) and quality of life (QoL) ... Read more >>

Minerva Med (Minerva medica)
[2021, 112(1):81-95]

Cited: 1 time

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Primary site disease and recurrence location in ovarian cancer patients undergoing primary debulking surgery vs. interval debulking surgery.

Capozzi Vito Andrea, Stefano Uccella, Giulio Sozzi, Marcello Ceccaroni, Daniele Mautone, Giulia Armano, Massimo Franchi, Vito Chiantera, Roberto Berretta,

<h4>Introduction</h4>The natural history and patterns of ovarian cancer (OC) relapse are still unclear. Recurrent disease can be peritoneal, parenchymal, or nodal. This study aims to analyze the location and pattern of OC recurrence according to the primary site of disease and to the type of surgical approach used.<h4>Material and methods</h4>All ... Read more >>

Eur J Surg Oncol (European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology)
[2020, :]

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The Case of a Serous Borderline Ovarian Tumor in a 15-Year Old Pregnant Adolescent: Sonographic Characteristics and Surgical Management.

Stefano Uccella, Manuela Rosa, Elena Biletta, Raffaele Tinelli, Pier C Zorzato, Chiara Botto-Poala, Gabriele Lanzo, Davide Gallina, Massimo P Franchi, Paolo Manzoni,

<h4>Objective</h4>This study aimed to describe a rare case of a serous borderline ovarian tumor (BOT) diagnosed during pregnancy in a 15-year old adolescent.<h4>Results</h4>The suspect of BOT was raised at a transvaginal ultrasound scan in early first trimester (at 5 weeks of amenorrhea), due to the presence of a moderately vascularized ... Read more >>

Am J Perinatol (American journal of perinatology)
[2020, 37(S 02):S61-S65]

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Percutaneous-Assisted versus Laparoscopic Hysterectomy: A Prospective Comparison.

Emanuele Perrone, Cristiano Rossitto, Francesco Fanfani, Stefano Cianci, Anna Fagotti, Stefano Uccella, Giuseppe Vizzielli, Carmine Vascone, Stefano Restaino, Camilla Fedele, Farrah Layla Saleh, Giovanni Scambia, Salvatore Gueli Alletti,

<h4>Objective</h4>To evaluate the feasibility of percutaneous approach, we prospectively compared our experience in percutaneous-assisted hysterectomy (PSS-H) with that in a series of laparoscopic hysterectomies (LPS-Hs).<h4>Methods</h4>In this multicentric cohort study, from May 2015 to October 2017, 160 patients affected by benign and malignant gynecological conditions were considered eligible for minimally invasive ... Read more >>

Gynecol Obstet Invest (Gynecologic and obstetric investigation)
[2020, 85(4):318-326]

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Vaginal Birth after Two Previous Cesarean Sections versus Elective Repeated Cesarean: A Retrospective Study.

Rossella De Leo, Domenico Antonio La Gamba, Paolo Manzoni, Raffaella De Lorenzi, Sonia Torresan, Massimo Franchi, Stefano Uccella,

<h4>Objective</h4>Trial of labor after cesarean delivery (TOLAC) is a common practice worldwide but the evidence is still scant regarding this practice in women who underwent 2 previous cesareans. The purpose of this study is to retrospectively review our experience with vaginal birth after two previous cesarean sections (VBA2C), with specific ... Read more >>

Am J Perinatol (American journal of perinatology)
[2020, 37(S 02):S84-S88]

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Laparoscopic sentinel node mapping with intracervical indocyanine green injection for endometrial cancer: the SENTIFAIL study - a multicentric analysis of predictors of failed mapping.

Giulio Sozzi, Francesco Fanfani, Roberto Berretta, Vito Andrea Capozzi, Stefano Uccella, Natalina Buono, Vincenzo Giallombardo, Mariano Catello Di Donna, Giorgia Monterossi, Stefano Restaino, Ilaria Capasso, Giorgia Dinoi, Giovanni Scambia, Vito Chiantera,

<h4>Objectives</h4>Laparoscopy is commonly used for endometrial cancer treatment, and sentinel lymph node (SLN) mapping has become the standard procedure for nodal assessment. Despite the standardization of the technique, there is no definitive data regarding its failure rate. The objective of this study is to identify factors associated with unsuccessful SLN ... Read more >>

Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2020, 30(11):1713-1718]

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Laparotomy vs. minimally invasive surgery for ovarian cancer recurrence: a systematic review.

Stefano Uccella, Massimo P Franchi, Stefano Cianci, Pier Carlo Zorzato, Francesca Bertoli, Salvatore Gueli Alletti, Fabio Ghezzi, Giovanni Scambia,

The objective of the present review is to thoroughly investigate the role of minimally invasive surgery (MIS) in the setting of secondary cytoreduction for ovarian cancer recurrence, comparing this approach to traditional open surgery. PubMed, ClinicalTrials.gov, Scopus and Web of Science databases (between 1st January 1989 and 1st January 2020), ... Read more >>

Gland Surg (Gland surgery)
[2020, 9(4):1130-1139]

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Role of ultrasound in the detection of recurrent ovarian cancer: a review of the literature.

Andrea Rosati, Salvatore Gueli Alletti, Vito Andrea Capozzi, Mariateresa Mirandola, Virginia Vargiu, Camilla Fedele, Stefano Uccella, Carmine Vascone,

Nowadays, no standard approaches for follow up in ovarian cancer (OC) patients exist. While the role of ultrasound (US) is well defined in primary diagnosis of OC, it is still controversial during follow-up of surgically treated OC. The aim of this narrative review is to evaluate the role described in ... Read more >>

Gland Surg (Gland surgery)
[2020, 9(4):1092-1101]

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Obturator nerve injury in a chemo and radio-resistant patient with a locally-advanced cervical cancer after two previous uterine artery embolizations for severe vaginal bleeding: Case report and review of literature.

Raffaele Tinelli, Stefano Uccella, Luigi Nappi, Giuseppe D'Amato, Ettore Cicinelli, Stefano Angioni,

Chemo and radiotherapy are actually the gold standard of treatment for locally-advanced cervical cancer. We report a case report showing a repaired (video 1) right obturator nerve after an incidental injury during a right internal iliac artery closure with 10 mm titanium clip for severe pelvic bleeding in a patient ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2020, 252:355-358]

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Surgery-related complications and long-term functional morbidity after segmental colo-rectal resection for deep infiltrating endometriosis (ENDO-RESECT morb).

Luigi Carlo Turco, Lucia Tortorella, Attilio Tuscano, Marco Antonio Palumbo, Anna Fagotti, Stefano Uccella, Francesco Fanfani, Gabriella Ferrandina, Nicola Nicolotti, Virginia Vargiu, Claudio Lodoli, Franco Scaldaferri, Giovanni Scambia, Francesco Cosentino,

<h4>Purpose</h4>Segmental resection has been generally associated with increased peri-operative risk of major complications. While major complications are widely acknowledged, minor complications, such as slight, to moderate infections, peripheral sensory disturbances, bladder voiding dysfunction, postoperative urinary obstruction, and sexual disorders are less reported. The aim of this study is to investigate ... Read more >>

Arch Gynecol Obstet (Archives of gynecology and obstetrics)
[2020, 302(4):983-993]

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Psychological Impact of a Pandemic Widespread in Healthcare Workers: The Italian and Swiss Perspective Early After of CoVid-19 Outbreak

Laura Uccella, Pietro Majno-Hurst, Sara Uccella, Luca Jacopo Pavan, Stefano Uccella, Cesare Zoia, Francesco Mongelli,

<h4>Background: </h4> We investigated the COVID19-related psychological impact in healthcare workers three weeks after its onset in Italy and in Italian-speaking regions of Switzerland. All professional groups of public hospitals in Italy and Switzerland were asked to complete a 38 questions online survey investigating demographic, marital and working status, presence ... Read more >>

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Novel preoperative predictive score to evaluate lymphovascular space involvement in endometrial cancer: an aid to the sentinel lymph node algorithm.

Vito Andrea Capozzi, Giulio Sozzi, Stefano Uccella, Valentina Ceni, Alessandra Cianciolo, Giulia Gambino, Giulia Armano, Martina Pugliese, Giovanni Scambia, Vito Chiantera, Roberto Berretta,

INTRODUCTION:Sentinel lymph node (SLN) dissection has been recognized as a valid tool for staging in patients with endometrial cancer. Several factors are predictors of recurrence and survival in endometrial cancer, including positive lymphovascular space invasion. The aim of this study is to formulate a pre-operative score that, in the event ... Read more >>

Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2020, 30(6):806-812]

Cited: 1 time

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Laparoscopic treatment of ovarian granulosa cells tumor developed in the pelvic anterior preperitoneal space 20 years after laparotomic salpingo-oophorectomy: case report and review of literature.

Raffaele Tinelli, Massimo Stomati, Giuseppe Trojano, Stefano Uccella, Francesco Cosentino, Ettore Cicinelli, Stefano Angioni,

Granulosa cells (GC) tumors are rare tumors which account for approximately 2-3% of all ovarian malignancies with a favorable prognosis. We report a case of a 54-year-old postmenopausal woman who developed an ovarian GC tumor in the pelvic anterior preperitoneal space 20 years after laparotomic salpingo-oophorectomy due to small part of ... Read more >>

Gynecol Endocrinol (Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology)
[2020, 36(10):926-928]

Cited: 1 time

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Feasibility and perioperative outcomes of percutaneous-assisted laparoscopic hysterectomy: A multicentric Italian experience.

Salvatore Gueli Alletti, Emanuele Perrone, Antonio Cretì, Stefano Cianci, Stefano Uccella, Camilla Fedele, Francesco Fanfani, Stefano Palmieri, Anna Fagotti, Giovanni Scambia, Cristiano Rossitto,

OBJECTIVE:This multicentric prospective phase II study aimed to investigate the feasibility, safety, and efficacy of percutaneous-assisted laparoscopic hysterectomy in terms of perioperative outcomes, feasibility, VAS score, and cosmetic outcomes. STUDY DESIGN:Between May 2015 and October 2017, 382 patients were considered eligible for minimally invasive percutaneous-assisted laparoscopic hysterectomy using Percuvance™, Percutaneous ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2020, 245:181-185]

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