Emanuele Perrone, Ilaria Capasso, Tina Pasciuto, Alessandro Gioè, Salvatore Gueli Alletti, Stefano Restaino, Giovanni Scambia, Francesco Fanfani,
<h4>Objective</h4>The aim of this study is to analyze and draw the potential differences between the robotic-assisted surgery (RS) and the laparoscopy (LPS) in endometrial cancer staging.<h4>Methods</h4>In this single-institution retrospective study we enrolled 1,221 consecutive clinical stage I-III endometrial cancer patients undergone minimally invasive surgical staging. We compared patients treated by ... Read more >>
J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(3):e45]
Cited: 0 times
Lucia Tortorella, Stefano Restaino, Gian Franco Zannoni, Giuseppe Vizzielli, Vito Chiantera, Serena Cappuccio, Alessandro Gioè, Eleonora La Fera, Giorgia Dinoi, Giuseppe Angelico, Giovanni Scambia, Francesco Fanfani,
<h4>Objective</h4>The aim of this study is to analyze the prognostic role of lymph-vascular space invasion (LVSI), evaluated in a semi-quantitative fashion on prognosis of early stage, low risk endometrial cancer (EC).<h4>Methods</h4>We enrolled patients who underwent surgery for endometrial cancer between 2003 and 2018 in two referral cancer center. All patients ... Read more >>
J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e11]
Cited: 1 time
Silvia Pelligra, Giuseppe Scaletta, Stefano Cianci, Salvatore Gueli Alletti, Stefano Restaino, Anna Fagotti, Giovanni Scambia, Francesco Fanfani,
In most cancers, lymph node status is the most critical factor impacting the evolution of the disease and the overall survival. Identifying potential nodal metastasis allows the oncologist to adjust the stage and, consequently, the patient's treatment. For this reason, a precise evaluation of the regional nodes is mandatory. In ... Read more >>
Minerva Ginecol (Minerva ginecologica)
[2020, 72(6):404-412]
Cited: 0 times
Stefano Restaino, Lucia Tortorella, Giorgia Dinoi, Gian-Franco Zannoni, Alessandro Baroni, Ilaria Capasso, Ettore Distefano, Giulio Sozzi, Vito Chiantera, Giovanni Scambia, Francesco Fanfani,
<h4>Objectives</h4>The interpretation of lymph-vascular space invasion (LVSI) is usually qualitative, as presence or absence. The aim of this study is to investigate the prognostic role of LVSI in patients affected by endometrial cancer, when evaluated with a semiquantitative analysis.<h4>Methods</h4>This retrospective multicentre study enrolled patients who received a histologically confirmed diagnosis ... Read more >>
Eur J Cancer (European journal of cancer (Oxford, England : 1990))
[2021, 142:29-37]
Cited: 0 times
Emanuele Perrone, Cristiano Rossitto, Francesco Fanfani, Stefano Cianci, Anna Fagotti, Stefano Uccella, Giuseppe Vizzielli, Carmine Vascone, Stefano Restaino, Camilla Fedele, Farrah Layla Saleh, Giovanni Scambia, Salvatore Gueli Alletti,
<h4>Objective</h4>To evaluate the feasibility of percutaneous approach, we prospectively compared our experience in percutaneous-assisted hysterectomy (PSS-H) with that in a series of laparoscopic hysterectomies (LPS-Hs).<h4>Methods</h4>In this multicentric cohort study, from May 2015 to October 2017, 160 patients affected by benign and malignant gynecological conditions were considered eligible for minimally invasive ... Read more >>
Gynecol Obstet Invest (Gynecologic and obstetric investigation)
[2020, 85(4):318-326]
Cited: 0 times
Giulio Sozzi, Francesco Fanfani, Roberto Berretta, Vito Andrea Capozzi, Stefano Uccella, Natalina Buono, Vincenzo Giallombardo, Mariano Catello Di Donna, Giorgia Monterossi, Stefano Restaino, Ilaria Capasso, Giorgia Dinoi, Giovanni Scambia, Vito Chiantera,
<h4>Objectives</h4>Laparoscopy is commonly used for endometrial cancer treatment, and sentinel lymph node (SLN) mapping has become the standard procedure for nodal assessment. Despite the standardization of the technique, there is no definitive data regarding its failure rate. The objective of this study is to identify factors associated with unsuccessful SLN ... Read more >>
Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2020, 30(11):1713-1718]
Cited: 0 times
Lorenzo Vacca, Alessandro Lucidi, Giovanni Panico, Giuseppe Campagna, Stefano Restaino, Alfredo Ercoli, Giovanni Scambia, Francesco Fanfani,
<h4>Objective</h4>In this series we investigate the safety, feasibility and efficacy of our laparoscopic modified Shull technique describing the fundamental aspects of this surgical procedure in order to add a new feasible abdominal approach for apex resuspension.<h4>Study design</h4>A retrospective case series of 10 patients referring to our Urogynecological department for symptomatic ... Read more >>
Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2020, 253:83-89]
Cited: 0 times
Stefano Restaino, Liliana Mereu, Angelo Finelli, Maria Roberta Spina, Giulia Marini, Ursula Catena, Luigi Carlo Turco, Rossana Moroni, Michela Milani, Vito Cela, Giovanni Scambia, Francesco Fanfani,
Endometriosis is one of the most common medical conditions affecting the women. The study aimed to evaluate the safety and efficacy of robotic-assisted laparoscopic surgery (RAS) versus conventional laparoscopic surgery (LPS) in the treatment of endometriosis. PubMed, Embase, Cochrane and CINAHL databases were searched from January 1995 to March 2019. According to ... Read more >>
J Robot Surg (Journal of robotic surgery)
[2020, 14(5):687-694]
Cited: 0 times
Francesco Fanfani, Giorgia Monterossi, Maria Letizia Di Meo, Eleonora La Fera, Federica Dell'Orto, Alessandro Gioè, Maria Lamanna, Debora Ferrari, Elena De Ponti, Patrizia Perego, Stefano Restaino, Ronsini Carlo, Gian Franco Zannoni, Fabio Landoni, Giovanni Scambia, Alessandro Buda,
INTRODUCTION:The objective of this study was to compared standard ultra-staging (SU) with one-step nucleic acid amplification (OSNA) for the detection of sentinel lymph node (SLN) metastasis in women with apparent uterine-confined endometrial cancer. METHODS:All women underwent SLN identification with complete surgical staging. All SLNs were cut perpendicular to the long ... Read more >>
Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2020, 30(3):372-377]
Cited: 0 times
Francesco Legge, Stefano Restaino, Luca Leone, Vito Carone, Carlo Ronsini, Giacomo Lorenzo Maria Di Fiore, Tina Pasciuto, Silvia Pelligra, Francesca Ciccarone, Giovanni Scambia, Francesco Fanfani,
<h4>Introduction</h4>Recurrence of endometrial cancer is an important clinical challenge, with median survival rarely exceeding 12 months. The aim of this study was to analyze patterns of endometrial cancer recurrence and associations of these patterns with clinical outcome.<h4>Methods</h4>The study included patients with endometrial cancer who underwent primary surgical treatment with or ... Read more >>
Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2020, 30(2):193-200]
Cited: 0 times
Salvatore Gueli Alletti, Stefano Restaino, Angelo Finelli, Carlo Ronsini, Alessandro Lucidi, Giovanni Scambia, Francesco Fanfani,
<h4>Study objective</h4>To reveal principles and the feasibility of a total laparoscopic hysterectomy (TLH) with uterine artery ligation at the origin.<h4>Design</h4>Step-by-step demonstration and explanation of technique using videos from patients.<h4>Setting</h4>Gynecologic oncology unit at a university hospital.<h4>Patient</h4>A 54-year-old woman with uterine fibromatosis and metrorrhagia.<h4>Intervention</h4>TLH has 7 common components. First, round ligaments are ... Read more >>
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2020, 27(1):22-23]
Cited: 1 time
Stefano Restaino, Alessandro Lucidi, Angelo Finelli, Carlo Ronsini, Antonia Iacovelli, Francesco Fanfani,
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2019, 26(2):371-372]
Cited: 0 times
Alessandro Buda, Stefano Restaino, Giampaolo Di Martino, Elena De Ponti, Giorgia Monterossi, Giorgia Dinoi, Sonia Magni, Lorena Quagliozzi, Federica Dell'Orto, Francesca Ciccarone, Maria Lamanna, Giovanni Scambia, Fabio Landoni, Francesco Fanfani,
<h4>Objectives</h4>The majority of endometrial cancers (EC) are discovered while the disease is confined to the uterine body. The presence of lymph nodes metastases impairs the prognosis. In this study, we evaluated the possible impact on survival of sentinel lymph node (SLN) mapping algorithm and selective lymphadenectomy (LD) in early stage ... Read more >>
Eur J Surg Oncol (European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology)
[2018, 44(10):1562-1567]
Cited: 2 times
Stefano Restaino, Carlo Ronsini, Angelo Finelli, Alessandro Santarelli, Giovanni Scambia, Francesco Fanfani,
STUDY OBJECTIVE:To prove the feasibility of the Shull technique by a laparoscopic approach in a patient affected by pelvic organ prolapse (POP) with apical loss of support. DESIGN:A step-by-step video demonstration (Canadian Task Force classification III). SETTING:University hospital. Ethics Committee ruled that approval was not required for this study. PATIENT:A ... Read more >>
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2018, 25(6):954]
Cited: 0 times
Stefano Restaino, Francesco Fanfani, Matteo Vittori, Alessandro D'Addessi, Giovanni Scambia, Barbara Costantini,
We present the first reported case of a patient with a forgotten ureteral stent. A 68-year-old woman had undergone radical hysterectomy for cervical cancer in 1997, at which time bilateral ureteral stents were placed. She was admitted to our hospital with stranguria, dysuria, and lower back pain of 10 days ... Read more >>
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2018, 25(5):920-922]
Cited: 0 times
Stefano Restaino, Carlo Ronsini, Angelo Finelli, Emanuele Perrone, Giovanni Scambia, Francesco Fanfani,
Background:Sentinel Lymphonode analysis has become a barely new and innovative way to treat early stages of endometrial cancer (Ballester et al., Lancet Oncol 469-476, 2011; Buda et al., Ann Surg Oncol 2975-81, 2016). Indocyanine green cervical injection is considered gold standard for mapping nodes' drainage. Blue dye is used as ... Read more >>
Gynecol Surg (Gynecological surgery)
[2017, 14(1):23]
Cited: 3 times
Alessandro Buda, Giampaolo Di Martino, Stefano Restaino, Elena De Ponti, Giorgia Monterossi, Daniela Giuliani, Alfredo Ercoli, Federica Dell'Orto, Giorgia Dinoi, Tommaso Grassi, Giovanni Scambia, Francesco Fanfani,
The role of lymphadenectomy in endometrial cancer is still uncertain. We aimed to evaluate the survival outcomes of two different strategies in apparent uterine confined disease by comparing sentinel lymph node (SLN) mapping and selective lymphadenectomy (LD).We retrospectively reviewed women with preoperative stage I endometrial cancer underwent surgical staging with ... Read more >>
Gynecol Oncol (Gynecologic oncology)
[2017, 147(3):528-534]
Cited: 5 times
Francesco Fanfani, Stefano Restaino, Stefania Cicogna, Marco Petrillo, Marcella Montico, Emanuele Perrone, Oriano Radillo, Rossella De Leo, Matteo Ceccarello, Giovanni Scambia, Giuseppe Ricci,
<h4>Objective</h4>The aim of the study was to evaluate the prognostic value of human epididymis protein 4 (HE4) and cancer antigen 125 markers with pathological prognostic factor to complete the preoperative clinical panel and help the treatment planning.<h4>Methods</h4>This prospective multicenter study was conducted in 2 gynecologic oncology centers between 2012 and ... Read more >>
Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2017, 27(6):1200-1205]
Cited: 1 time
Giorgia Monterossi, Fabio Ghezzi, Enrico Vizza, Gian Franco Zannoni, Stefano Uccella, Giacomo Corrado, Stefano Restaino, Lorena Quagliozzi, Jvan Casarin, Giorgia Dinoi, Giovanni Scambia, Francesco Fanfani,
<h4>Study objective</h4>To compare perioperative and survival outcomes in patients with type II endometrial cancer surgically staged by a minimally invasive surgery (MIS) approach and those surgically staged by laparotomy.<h4>Design</h4>Retrospective cohort study (Canadian Task Force classification II-2).<h4>Setting</h4>Catholic University of the Sacred Heart of Rome, University of Insubria, Varese and "Regina Elena" ... Read more >>
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2017, 24(3):438-445]
Cited: 5 times
Francesco Fanfani, Stefano Restaino, Cristiano Rossitto, Salvatore Gueli Alletti, Barbara Costantini, Giorgia Monterossi, Serena Cappuccio, Emanuele Perrone, Giovanni Scambia,
<h4>Study objective</h4>To compare the feasibility and safety of the TELELAP ALF-X system and standard laparoscopy for total hysterectomy to treat patients with benign and early malignant gynecologic disease.<h4>Design</h4>Single-institution retrospective case-control study (Canadian Task Force classification II-2).<h4>Setting</h4>Catholic University of the Sacred Heart, Rome, Italy.<h4>Patients</h4>Between October 2013 and May 2015, 203 women ... Read more >>
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2016, 23(6):933-938]
Cited: 12 times
Francesco Fanfani, Cristiano Rossitto, Stefano Restaino, Alfredo Ercoli, Vito Chiantera, Giorgia Monterossi, Giulia Barbati, Giovanni Scambia,
This randomized clinical trial (Canadian Task Force classification I) aimed to compare 2-dimension (2-D) versus 3-dimensional (3-D) laparoscopic hysterectomy and pelvic lymphadenectomy in endometrial and cervical cancer patients. Between December 2014 and March 2015, 90 patients were enrolled: 29 (32.2%) with early or locally advanced cervical cancer after neoadjuvant treatment ... Read more >>
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2016, 23(5):810-817]
Cited: 2 times
Francesco Fanfani, Stefano Restaino, Alfredo Ercoli, Vito Chiantera, Anna Fagotti, Valerio Gallotta, Giorgia Monterossi, Serena Cappuccio, Giovanni Scambia,
This review of the literature aims at assessing the safety and effectiveness of robotic versus laparoscopic surgery in benign and malignant gynecological diseases. Robotic-assisted laparoscopy is already widely used in the United States and Europe for the main gynecological procedure - hysterectomy - and has proved feasible and comfortable for ... Read more >>
Minerva Ginecol (Minerva ginecologica)
[2016, 68(4):423-430]
Cited: 1 time
Salvatore Gueli Alletti, Cristiano Rossitto, Stefano Cianci, Stefano Restaino, Barbara Costantini, Francesco Fanfani, Anna Fagotti, Francesco Cosentino, Giovanni Scambia,
<h4>Study objective</h4>To compare the surgical and clinical outcomes of patients affected by early-stage endometrial cancer treated using the Telelap ALF-X platform versus conventional laparoscopic surgery.<h4>Design</h4>Single institution retrospective cohort study (Canadian Task Force classification II-2).<h4>Setting</h4>Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Catholic University of the Sacred Heart, Rome, Italy.<h4>Patients</h4>The ... Read more >>
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2016, 23(3):378-383]
Cited: 11 times
Francesco Fanfani, Anna Fagotti, Alfredo Ercoli, Valerio Gallotta, Vito Chiantera, Stefano Restaino, Giorgia Monterossi, Giovanni Scambia,
<h4>Background</h4>The aim of the present study was to evaluate the efficacy of tertiary and quaternary cytoreduction in recurrent ovarian cancer patients.<h4>Patients and methods</h4>Between January 1997 and December 2014, 53 patients were submitted to cytoreductive surgery for second and third ovarian cancer recurrence at our Unit.<h4>Results</h4>Median age at first diagnosis was ... Read more >>
Anticancer Res (Anticancer research)
[2015, 35(12):6951-6955]
Cited: 3 times
Francesco Fanfani, Stefano Restaino, Salvatore Gueli Alletti, Anna Fagotti, Giorgia Monterossi, Cristiano Rossitto, Barbara Costantini, Giovanni Scambia,
<h4>Study objective</h4>To show the safety, feasibility, and perioperative outcomes of total TELELAP ALF-X hysterectomy (SOFAR S.p.A., ALF-X Surgical Robotics Department, Trezzano Rosa, Milan, Italy).<h4>Design</h4>Phase II study (Canadian Task Force II-2).<h4>Setting</h4>Catholic University of the Sacred Heart, Rome, Italy.<h4>Patients</h4>From October 2013 to May 2014, 80 women underwent total TELELAP ALF-X hysterectomy. The ... Read more >>
J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2015, 22(6):1011-1017]
Cited: 11 times