Full Text Journal Articles by
Author Stefan D Anker

Advertisement

Find full text journal articles






Advanced cancer is also a heart failure syndrome - an hypothesis.

Markus S Anker, Ana Pardo Sanz, José L Zamorano, Mandeep R Mehra, Javed Butler, Hanno Riess, Andrew J S Coats, Stefan D Anker,

We present the hypothesis that advanced stage cancer is also a heart failure syndrome. It can develop independently of or in addition to cardiotoxic effects of anti-cancer therapies. This includes an increased risk of ventricular arrhythmias. We suggest the pathophysiologic link for these developments includes generalized muscle wasting (i.e. sarcopenia) ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Effects of empagliflozin on first and recurrent clinical events in patients with type 2 diabetes and atherosclerotic cardiovascular disease: a secondary analysis of the EMPA-REG OUTCOME trial.

Darren K McGuire, Bernard Zinman, Silvio E Inzucchi, Christoph Wanner, David Fitchett, Stefan D Anker, Stuart Pocock, Stefan Kaspers, Jyothis T George, Maximilian von Eynatten, Odd Erik Johansen, Waheed Jamal, Michaela Mattheus, Ulrich Elsasser, Stefan Hantel, Søren S Lund,

BACKGROUND:Patients with type 2 diabetes and atherosclerotic cardiovascular disease are at high clinical risk. We assessed the effect of the sodium-glucose co-transporter-2 inhibitor, empagliflozin, on total cardiovascular events and admissions to hospital in the EMPA-REG OUTCOME trial. METHODS:The EMPA-REG OUTCOME trial was a randomised, double-blind, non-inferiority trial of patients (aged ... Read more >>

Lancet Diabetes Endocrinol (The lancet. Diabetes & endocrinology)
[2020, 8(12):949-959]

Cited: 0 times

View full text PDF listing >>



Advertisement

Ventricular tachycardia, premature ventricular contractions, and mortality in unselected patients with lung, colon, or pancreatic cancer: a prospective study.

Markus S Anker, Stephan von Haehling, Andrew Js Coats, Hanno Riess, Jan Eucker, Jan Porthun, Javed Butler, Mahir Karakas, Wilhelm Haverkamp, Ulf Landmesser, Stefan D Anker,

AIMS:Many cancer patients die due to cardiovascular disease and sudden death, but data on ventricular arrhythmia prevalence and prognostic importance are not known. METHODS AND RESULTS:Between 2005 and 2010, we prospectively enrolled 120 unselected patients with lung, colon, or pancreatic cancer due to one of three diagnoses: colorectal (n=33), pancreatic ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Discontinuation and non-publication of heart failure randomized controlled trials: a call to publish all trial results.

Muhammad Shahzeb Khan, Izza Shahid, Nava Asad, Stephen J Greene, Safi U Khan, Rami Doukky, Marco Metra, Stefan D Anker, Gerasimos S Filippatos, Gregg C Fonarow, Javed Butler,

AIMS:Discontinuation or non-publication of trials may hinder scientific progress and violates the commitment made to research participants. We sought to identify the prevalence of discontinuation and non-publication of heart failure (HF) clinical trials. METHODS AND RESULTS:We conducted a cross-sectional search of ClinicalTrials.gov to identify all completed and discontinued HF clinical ... Read more >>

ESC Heart Fail (ESC heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Finerenone and Cardiovascular Outcomes in Patients with Chronic Kidney Disease and Type 2 Diabetes.

Gerasimos Filippatos, Stefan D Anker, Rajiv Agarwal, Bertram Pitt, Luis M Ruilope, Peter Rossing, Peter Kolkhof, Patrick Schloemer, Ingo Tornus, Amer Joseph, George L Bakris, ,

Background: The FIDELIO-DKD trial evaluated the effect of the nonsteroidal, selective mineralocorticoid receptor antagonist finerenone on kidney and cardiovascular (CV) outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) with optimized renin-angiotensin system blockade. Compared with placebo, finerenone reduced the composite kidney and CV outcomes. We ... Read more >>

Circulation (Circulation)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial.

Piotr Ponikowski, Bridget-Anne Kirwan, Stefan D Anker, Theresa McDonagh, Maria Dorobantu, Jarosław Drozdz, Vincent Fabien, Gerasimos Filippatos, Udo Michael Göhring, Andre Keren, Irakli Khintibidze, Hans Kragten, Felipe A Martinez, Marco Metra, Davor Milicic, José C Nicolau, Marcus Ohlsson, Alexander Parkhomenko, Domingo A Pascual-Figal, Frank Ruschitzka, David Sim, Hadi Skouri, Peter van der Meer, Basil S Lewis, Josep Comin-Colet, Stephan von Haehling, Alain Cohen-Solal, Nicolas Danchin, Wolfram Doehner, Henry J Dargie, Michael Motro, Javed Butler, Tim Friede, Klaus H Jensen, Stuart Pocock, Ewa A Jankowska, ,

BACKGROUND:Intravenous ferric carboxymaltose has been shown to improve symptoms and quality of life in patients with chronic heart failure and iron deficiency. We aimed to evaluate the effect of ferric carboxymaltose, compared with placebo, on outcomes in patients who were stabilised after an episode of acute heart failure. METHODS:AFFIRM-AHF was ... Read more >>

Lancet (Lancet (London, England))
[2020, :]

Cited: 0 times

View full text PDF listing >>



Effect of Empagliflozin on Cardiovascular and Renal Outcomes in Patients With Heart Failure by Baseline Diabetes Status - Results from the EMPEROR-Reduced Trial.

Stefan D Anker, Javed Butler, Gerasimos Filippatos, Muhammad Shahzeb Khan, Nikolaus Marx, Carolyn S P Lam, Sven Schnaidt, Anne Pernille Ofstad, Martina Brueckmann, Waheed Jamal, Edimar Bocchi, Piotr Ponikowski, Sergio V Perrone, James L Januzzi, Subodh Verma, Michael Böhm, João Pedro Ferreira, Stuart J Pocock, Faiez Zannad, Milton Packer, ,

Background: Sodium-glucose cotransporter 2 (SGLT2) inhibitors improve outcomes in patients with heart failure with reduced ejection fraction, but additional information is needed about whether glycemic status influences the magnitude of their benefits on heart failure and renal events. Methods: Patients with class II-IV heart failure and a left ventricular ejection ... Read more >>

Circulation (Circulation)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Preserved Skeletal Muscle Mitochondrial Function, Redox State, Inflammation and Mass in Obese Mice with Chronic Heart Failure.

Gianluca Gortan Cappellari, Aneta Aleksova, Matteo Dal Ferro, Antonio Cannatà, Annamaria Semolic, Michela Zanetti, Jochen Springer, Stefan D Anker, Mauro Giacca, Gianfranco Sinagra, Rocco Barazzoni,

Background: Skeletal muscle (SM) mitochondrial dysfunction, oxidative stress, inflammation and muscle mass loss may worsen prognosis in chronic heart failure (CHF). Diet-induced obesity may also cause SM mitochondrial dysfunction as well as oxidative stress and inflammation, but obesity per se may be paradoxically associated with high SM mass and mitochondrial ... Read more >>

Nutrients (Nutrients)
[2020, 12(11):]

Cited: 0 times

View full text PDF listing >>



Standardized Definitions for Evaluation of Heart Failure Therapies: Scientific Expert Panel From the Heart Failure Collaboratory and Academic Research Consortium.

William T Abraham, Mitchell A Psotka, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Roxana Mehran, Amrut V Ambardekar, Peter E Carson, Richard Jacob, James L Januzzi, Marvin A Konstam, Mitchell W Krucoff, Eldrin F Lewis, Jonathan P Piccini, Scott D Solomon, Norman Stockbridge, John R Teerlink, Ellis F Unger, Emily P Zeitler, Stefan D Anker, Christopher M O'Connor,

The Heart Failure Academic Research Consortium is a partnership between the Heart Failure Collaboratory (HFC) and Academic Research Consortium (ARC), comprised of leading heart failure (HF) academic research investigators, patients, United States (US) Food and Drug Administration representatives, and industry members from the US and Europe. A series of meetings were convened ... Read more >>

JACC Heart Fail (JACC. Heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Correction to: The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure.

Bernadet T Santema, Michelle M Y Chan, Jasper Tromp, Martin Dokter, Haye H van der Wal, Johanna E Emmens, Janny Takens, Nilesh J Samani, Leong L Ng, Chim C Lang, Peter van der Meer, Jozine M Ter Maaten, Kevin Damman, Kenneth Dickstein, John G Cleland, Faiez Zannad, Stefan D Anker, Marco Metra, Pim van der Harst, Rudolf A de Boer, Dirk J van Veldhuisen, Michiel Rienstra, Carolyn S P Lam, Adriaan A Voors,

The original article can be found online. ... Read more >>

Clin Res Cardiol (Clinical research in cardiology : official journal of the German Cardiac Society)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.

Mitchell A Psotka, William T Abraham, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Tariq Ahmad, Ankeet S Bhatt, Peter E Carson, John G F Cleland, G Michael Felker, James L Januzzi, Dalane W Kitzman, Eric S Leifer, Eldrin F Lewis, John J V McMurray, Robert J Mentz, Scott D Solomon, Norman Stockbridge, John R Teerlink, Muthiah Vaduganathan, Orly Vardeny, David J Whellan, Janet Wittes, Stefan D Anker, Christopher M O'Connor,

The coronavirus disease-2019 (COVID-19) pandemic has profoundly changed clinical care and research, including the conduct of clinical trials, and the clinical research ecosystem will need to adapt to this transformed environment. The Heart Failure Academic Research Consortium is a partnership between the Heart Failure Collaboratory and the Academic Research Consortium, composed of ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2020, 76(20):2368-2378]

Cited: 0 times

View full text PDF listing >>



High Soluble Transferrin Receptor in Patients With Heart Failure: a Measure of Iron Deficiency And a Strong Predictor of Mortality.

Radoslaw Sierpinski, Krystian Josiak, Tomasz Suchocki, Katarzyna Wojtas-Polc, Grzegorz Mazur, Aleksandra Butrym, Piotr Rozentryt, Peter van der Meer, Josep Comin-Colet, Stephan von Haehling, Wojciech Kosmala, Monika Przewlocka-Kosmala, Waldemar Banasiak, Jolanta Nowak, Adriaan A Voors, Stefan D Anker, John Gf Cleland, Piotr Ponikowski, Ewa A Jankowska,

BACKGROUND:Iron deficiency (ID) is frequent in heart failure (HF), linked with exercise intolerance and poor prognosis. Intravenous iron repletion improves clinical status in HF patients with LVEF≤45%. However, uncertainty exists about the accuracy of serum biomarkers in diagnosing ID. STUDY AIMS:1) to identify the iron biomarker with the greatest accuracy ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



A current and future outlook on upcoming technologies in remote monitoring of patients with heart failure.

Tarek Bekfani, Marat Fudim, John G F Cleland, Ana Jorbenadze, Stephan von Haehling, Avraham Lorber, Alexander M K Rothman, Kenneth Stein, William T Abraham, Horst Sievert, Stefan D Anker,

Heart failure is a major health and economic challenge in both developing and developed countries. Despite advances in pharmacological and device therapies for patients with a reduced left ventricular ejection fraction (LVEF) and heart failure, their quality of life and exercise capacity are often persistently impaired, morbidity and mortality remain ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).

Rudolf A de Boer, Jean-Sébastien Hulot, Carlo Gabriele Tocchetti, Joseph Pierre Aboumsallem, Pietro Ameri, Stefan D Anker, Johann Bauersachs, Edoardo Bertero, Andrew J S Coats, Jelena Čelutkienė, Ovidiu Chioncel, Pierre Dodion, Thomas Eschenhagen, Dimitrios Farmakis, Antoni Bayes-Genis, Dirk Jäger, Ewa A Jankowska, Richard N Kitsis, Suma H Konety, James Larkin, Lorenz Lehmann, Daniel J Lenihan, Christoph Maack, Javid J Moslehi, Oliver J Müller, Patrycja Nowak-Sliwinska, Massimo Francesco Piepoli, Piotr Ponikowski, Radek Pudil, Peter P Rainer, Frank Ruschitzka, Douglas Sawyer, Petar M Seferovic, Thomas Suter, Thomas Thum, Peter van der Meer, Linda W Van Laake, Stephan von Haehling, Stephane Heymans, Alexander R Lyon, Johannes Backs,

The co-occurrence of cancer and heart failure (HF) represents a significant clinical drawback as each disease interferes with the treatment of the other. In addition to shared risk factors, a growing body of experimental and clinical evidence reveals numerous commonalities in the biology underlying both pathologies. Inflammation emerges as a ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Cardiac and Kidney Benefits of Empagliflozin in Heart Failure Across the Spectrum of Kidney Function: Insights from the EMPEROR-Reduced Trial.

Faiez Zannad, João Pedro Ferreira, Stuart J Pocock, Cordula Zeller, Stefan D Anker, Javed Butler, Gerasimos Filippatos, Sibylle Jenny Hauske, Martina Brueckmann, Egon Pfarr, Janet Schnee, Christoph Wanner, Milton Packer,

Background: In EMPEROR-Reduced, empagliflozin reduced cardiovascular death or HF hospitalization, total HF hospitalizations, and slowed the progressive decline in kidney function in patients with HF and a reduced ejection fraction (HFrEF), with and without diabetes. We aim to study the effect of empagliflozin on cardiovascular and kidney outcomes across the ... Read more >>

Circulation (Circulation)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Telemonitoring in patients with chronic heart failure and moderate depressed symptoms: results of the Telemedical Interventional Monitoring in Heart Failure (TIM-HF) study.

Johanna Koehler, Andreas Stengel, Tobias Hofmann, Karl Wegscheider, Kerstin Koehler, Susanne Sehner, Matthias Rose, Oliver Deckwart, Stefan D Anker, Friedrich Koehler, Ulrich Laufs,

AIMS:Depression is a frequent comorbidity in patients with chronic heart failure (CHF). Telemonitoring has emerged as a novel option in CHF care. However, patients with depression have been excluded in most telemedicine studies. This pre-specified subgroup analysis of the Telemedical Interventional Monitoring in Heart Failure (TIM-HF) trial investigates the effect ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Effect of Empagliflozin on the Clinical Stability of Patients with Heart Failure and a Reduced Ejection Fraction: The EMPEROR-Reduced Trial.

Milton Packer, Stefan D Anker, Javed Butler, Gerasimos S Filippatos, João Pedro Ferreira, Stuart Pocock, Peter E Carson, Inder S Anand, Wolfram Doehner, Markus Haass, Michel Komajda, Alan B Miller, Steen Pehrson, John R Teerlink, Martina Brueckmann, Waheed Jamal, Cordula Zeller, Sven Schnaidt, Faiez Zannad, ,

Background: Empagliflozin reduces the risk of cardiovascular death or hospitalization for heart failure in patients with heart failure and a reduced ejection fraction, with or without diabetes, but additional data are needed about the effect of the drug on inpatient and outpatient events that reflect worsening heart failure. Methods: We ... Read more >>

Circulation (Circulation)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Heart Failure Association of the European Society of Cardiology update on sodium-glucose co-transporter 2 inhibitors in heart failure (an update on the sodium-glucose co-transporter 2 inhibitors in heart failure: beyond glycaemic control. A position paper of the Heart Failure Association of the European Society of Cardiology).

Petar M Seferović, Gabriele Fragasso, Mark Petrie, Wilfried Mullens, Roberto Ferrari, Thomas Thum, Johann Bauersachs, Stefan D Anker, Robin Ray, Yuksel Çavuşoğlu, Marija Polovina, Marco Metra, Giuseppe Ambrosio, Krishna Prasad, Jelena Seferović, Pardeep S Jhund, Giuseppe Dattilo, Jelena Čelutkiene, Massimo Piepoli, Brenda Moura, Ovidiu Chioncel, Tuvia Ben Gal, Stephane Heymans, Tiny Jaarsma, Loreena Hill, Yuri Lopatin, Alexander R Lyon, Piotr Ponikowski, Mitja Lainščak, Ewa Jankowska, Christian Mueller, Francesco Cosentino, Lars H Lund, Gerasimos S Filippatos, Frank Ruschitzka, Andrew J S Coats, Giuseppe M C Rosano,

The Heart Failure Association (HFA) of the European Society of Cardiology (ESC) has recently issued a position paper on the role of sodium-glucose co-transporter 2 (SGLT2) inhibitors in heart failure (HF). The present document provides an update of the position paper, based of new clinical trial evidence. Accordingly, the following ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Differences in biomarkers and molecular pathways according to age for patients with HFrEF.

João Pedro Ferreira, Wouter Ouwerkerk, Bernadet T Santema, Dirk J van Veldhuisen, Chim C Lang, Leong L Ng, Stefan D Anker, Kenneth Dickstein, Marco Metra, John G F Cleland, Samani J Nilesh, Gerasimos Filippatos, Joseph-Pierre Aboumsallem, Rudolf A de Boer, Sylwia Figarska, Iziah E Sama, Adriaan A Voors, Faiez Zannad,

AIMS:Elderly patients with heart failure with reduced ejection fraction (HFrEF) have worse prognosis and less often receive guideline-recommended therapies. We aim to better understand the underlying pathophysiological processes associated with aging in HFrEF potentially leading to targeted therapies in this vulnerable population. METHODS AND RESULTS:From a panel of 363 cardiovascular ... Read more >>

Cardiovasc Res (Cardiovascular research)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Standardized definitions for evaluation of heart failure therapies: scientific expert panel from the Heart Failure Collaboratory and Academic Research Consortium.

William T Abraham, Mitchell A Psotka, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Roxana Mehran, Amrut V Ambardekar, Peter E Carson, Richard Jacob, James L Januzzi, Marvin A Konstam, Mitchell W Krucoff, Eldrin F Lewis, Jonathan P Piccini, Scott D Solomon, Norman Stockbridge, John R Teerlink, Ellis F Unger, Emily P Zeitler, Stefan D Anker, Christopher M O'Connor,

The Heart Failure Academic Research Consortium is a partnership between the Heart Failure Collaboratory (HFC) and Academic Research Consortium (ARC), comprised of leading heart failure (HF) academic research investigators, patients, United States (US) Food and Drug Administration representatives, and industry members from the US and Europe. A series of meetings ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Glucagon-Like Peptide 1 Receptor Agonists and Heart Failure: The Need for Further Evidence Generation and Practice Guidelines Optimization.

Muhammad Shahzeb Khan, Gregg C Fonarow, Darren K McGuire, Adrian F Hernandez, Muthiah Vaduganathan, Julio Rosenstock, Yehuda Handelsman, Subodh Verma, Stefan D Anker, John J V McMurray, Mikhail N Kosiborod, Javed Butler,

With worsening epidemiological trends for both the incidence and prevalence of type 2 diabetes mellitus (T2DM) and heart failure (HF) worldwide, it is critical to implement optimal prevention and treatment strategies for patients with these comorbidities, either alone or concomitantly. Several guidelines and consensus statements have recommended glucagon-like peptide-1 receptor ... Read more >>

Circulation (Circulation)
[2020, 142(12):1205-1218]

Cited: 0 times

View full text PDF listing >>



Ten lessons from the EMPEROR-Reduced trial.

Javed Butler, Faiez Zannad, Gerasimos Filippatos, Stefan D Anker, Milton Packer,

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Plasma D-dimer concentrations predicting stroke risk and rivaroxaban benefit in patients with heart failure and sinus rhythm: an analysis from the COMMANDER-HF trial.

João Pedro Ferreira, Carolyn S P Lam, Stefan D Anker, Mandeep R Mehra, Dirk J van Veldhuisen, William M Byra, David A La Police, John G F Cleland, Barry Greenberg, Faiez Zannad,

AIMS:D-dimer is a marker of fibrin degradation that reflects intravascular coagulation. Therefore, plasma concentrations of D-dimer might predict thromboembolic risk and rivaroxaban treatment effect. The aims of this study were to investigate the association between D-dimer levels and the risk of stroke and other thrombotic, bleeding and fatal events, and ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT): a randomised, double-blind, controlled trial.

Toby Richards, Ravishankar Rao Baikady, Ben Clevenger, Anna Butcher, Sandy Abeysiri, Marisa Chau, Iain C Macdougall, Gavin Murphy, Rebecca Swinson, Tim Collier, Laura Van Dyck, John Browne, Andrew Bradbury, Matthew Dodd, Richard Evans, David Brealey, Stefan D Anker, Andrew Klein,

BACKGROUND:Preoperative anaemia affects a high proportion of patients undergoing major elective surgery and is associated with poor outcomes. We aimed to test the hypothesis that intravenous iron given to anaemic patients before major open elective abdominal surgery would correct anaemia, reduce the need for blood transfusions, and improve patient outcomes. ... Read more >>

Lancet (Lancet (London, England))
[2020, :]

Cited: 0 times

View full text PDF listing >>



Liraglutide for Adolescents with Obesity.

Markus S Anker, Javed Butler, Stefan D Anker,

N Engl J Med (The New England journal of medicine)
[2020, 383(12):1192]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.3776 s