Full Text Journal Articles by
Author Stavros I Iliadis


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Cohort profile: the Biology, Affect, Stress, Imaging and Cognition (BASIC) study on perinatal depression in a population-based Swedish cohort.

Cathrine Axfors, Emma Bränn, Hanna E Henriksson, Charlotte Hellgren, Theodora Kunovac Kallak, Emma Fransson, Susanne Lager, Stavros I Iliadis, Sara Sylvén, Fotios C Papadopoulos, Lisa Ekselius, Inger Sundström-Poromaa, Alkistis Skalkidou,

PURPOSE:With the population-based, prospective Biology, Affect, Stress, Imaging and Cognition (BASIC) cohort, we aim to investigate the biopsychosocial aetiological processes involved in perinatal depression (PND) and to pinpoint its predictors in order to improve early detection. PARTICIPANTS:From September 2009 to November 2018, the BASIC study at Uppsala University Hospital, Sweden, ... Read more >>

BMJ Open (BMJ open)
[2019, 9(10):e031514]

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Blood plasma metabolic profiling of pregnant women with antenatal depressive symptoms.

Hanna E Henriksson, Christina Malavaki, Emma Bränn, Vasilis Drainas, Susanne Lager, Stavros I Iliadis, Fotios C Papadopoulos, Inger Sundström Poromaa, George P Chrousos, Maria I Klapa, Alkistis Skalkidou,

Antenatal depression affects ~9-19% of pregnant women and can exert persistent adverse effects on both mother and child. There is a need for a deeper understanding of antenatal depression mechanisms and the development of tools for reliable diagnosis and early identification of women at high risk. As the use of ... Read more >>

Transl Psychiatry (Translational psychiatry)
[2019, 9(1):204]

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Characteristics of women with different perinatal depression trajectories.

Anna Wikman, Cathrine Axfors, Stavros I Iliadis, John Cox, Emma Fransson, Alkistis Skalkidou,

Maternal perinatal depression (PND), a common mental disorder with a prevalence of over 10%, is associated with long-term health risks for both mothers and offspring. This study aimed at describing characteristics related to background and lifestyle, pregnancy, delivery, and postpartum of different PND trajectories defined according to the onset of ... Read more >>

J. Neurosci. Res. (Journal of neuroscience research)
[2019, :]

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Stress-related genetic polymorphisms in association with peripartum depression symptoms and stress hormones: A longitudinal population-based study.

Alkistis Skalkidou, Inger Sundström Poromaa, Stavros I Iliadis, Anja C Huizink, Charlotte Hellgren, Eva Freyhult, Erika Comasco,

Individual differences in the response of the stress system to hormonal changes during pregnancy and the postpartum period render some women susceptible to developing depression. The present study sought to investigate peripartum depression and stress hormones in relation to stress-related genotypes. The Edinburgh Postnatal Depression Scale was used to assess ... Read more >>

Psychoneuroendocrinology (Psychoneuroendocrinology)
[2019, 103:296-305]

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Women with prolonged nausea in pregnancy have increased risk for depressive symptoms postpartum.

Stavros I Iliadis, Cathrine Axfors, Sara Johansson, Alkistis Skalkidou, Ajlana Mulic-Lutvica,

The aim of this population-based, longitudinal study was to assess the association between nausea and vomiting in pregnancy (NVP) and perinatal depressive symptoms. Pregnant women (N = 4239) undergoing routine ultrasound at gestational week (GW) 17 self-reported on NVP and were divided into those without nausea (G0), early (≤17 GW) nausea without medication ... Read more >>

Sci Rep (Scientific reports)
[2018, 8(1):15796]

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Self-Harm Thoughts Postpartum as a Marker for Long-Term Morbidity.

Stavros I Iliadis, Alkistis Skalkidou, Hanna Ranstrand, Marios K Georgakis, Cathrine Axfors, Fotios C Papadopoulos,

Postpartum depression predisposes to maternal affective and somatic disorders. It is important to identify which women are at an increased risk of subsequent morbidity and would benefit from an intensified follow-up. Self-harm thoughts (SHTs), with or without other depressive symptomatology, might have prognostic value for maternal health beyond the postpartum ... Read more >>

Front Public Health (Frontiers in public health)
[2018, 6:34]

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Stavros I Iliadis, Sara Sylvén, Charlotte Hellgren, Jocelien D Olivier, Dick Schijven, Erika Comasco, George P Chrousos, Inger Sundström Poromaa, Alkistis Skalkidou,

Peripartum depression is a common cause of pregnancy- and postpartum-related morbidity. The production of corticotropin-releasing hormone (CRH) from the placenta alters the profile of hypothalamus-pituitary-adrenal axis hormones and may be associated with postpartum depression. The purpose of this study was to assess, in nondepressed pregnant women, the possible association between ... Read more >>

Depress Anxiety (Depression and anxiety)
[2016, 33(11):1023-1030]

Cited: 4 times

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Prenatal and Postpartum Evening Salivary Cortisol Levels in Association with Peripartum Depressive Symptoms.

Stavros I Iliadis, Erika Comasco, Sara Sylvén, Charlotte Hellgren, Inger Sundström Poromaa, Alkistis Skalkidou,

The biology of peripartum depression remains unclear, with altered stress and the Hypothalamus-Pituitary-Adrenal axis response having been implicated in its pathophysiology.The current study was undertaken as a part of the BASIC project (Biology, Affect, Stress, Imaging, Cognition), a population-based longitudinal study of psychological wellbeing during pregnancy and the postpartum period ... Read more >>

PLoS ONE (PloS one)
[2015, 10(8):e0135471]

Cited: 18 times

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Adipocytokines levels at delivery, functional variation of TFAP2β, and maternal and neonatal anthropometric parameters.

Erika Comasco, Stavros I Iliadis, Anders Larsson, Matts Olovsson, Lars Oreland, Inger Sundström-Poromaa, Alkistis Skalkidou,

OBJECTIVE: Adipocytokines participate in the regulation of glucose metabolism and fetal development. The transcription factor activating protein 2B (TFAP2β) has been associated with adipocytokine regulation, and gene variations with type 2 diabetes and obesity. This study investigated associations between maternal TFAP2B variation, adipocytokine levels, and maternal and neonatal anthropometric characteristics. ... Read more >>

Obesity (Silver Spring) (Obesity (Silver Spring, Md.))
[2013, 21(10):2130-2137]

Cited: 2 times

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