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Author Sripriya Sundararajan

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Short-term facilitation of breathing upon cessation of hypoxic challenge is impaired in male but not female endothelial NOS knock-out mice.

Paulina M Getsy, Sripriya Sundararajan, Walter J May, Graham C von Schill, Dylan K McLaughlin, Lisa A Palmer, Stephen J Lewis,

Decreases in arterial blood oxygen stimulate increases in minute ventilation via activation of peripheral and central respiratory structures. This study evaluates the role of endothelial nitric oxide synthase (eNOS) in the expression of the ventilatory responses during and following a hypoxic gas challenge (HXC, 10% O<sub>2</sub>, 90% N<sub>2</sub>) in freely ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18346]

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Ventilatory responses during and following hypercapnic gas challenge are impaired in male but not female endothelial NOS knock-out mice.

Paulina M Getsy, Sripriya Sundararajan, Walter J May, Graham C von Schill, Dylan K McLaughlin, Lisa A Palmer, Stephen J Lewis,

The roles of endothelial nitric oxide synthase (eNOS) in the ventilatory responses during and after a hypercapnic gas challenge (HCC, 5% CO2, 21% O2, 74% N2) were assessed in freely-moving female and male wild-type (WT) C57BL6 mice and eNOS knock-out (eNOS-/-) mice of C57BL6 background using whole body plethysmography. HCC ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):20557]

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Ideal blood inoculant volume for neonatal sepsis evaluation: an alternative approach.

Sripriya Sundararajan,

Pediatr Res (Pediatric research)
[2021, :]

Cited: 0 times

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Carotid sinus nerve transection abolishes the facilitation of breathing that occurs upon cessation of a hypercapnic gas challenge in male mice.

Paulina M Getsy, Sripriya Sundararajan, Stephen J Lewis,

Arterial pCO<sub>2</sub> elevations increase minute ventilation via activation of chemosensors within the carotid body (CB) and brainstem. Although the roles of CB chemoafferents in the hypercapnic (HC) ventilatory response have been investigated, there are no studies reporting the role of these chemoafferents in the ventilatory responses to a HC challenge ... Read more >>

J Appl Physiol (1985) (Journal of applied physiology (Bethesda, Md. : 1985))
[2021, 131(2):821-835]

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Ventilatory Responses During and Following Hypercapnic Gas Challenge are Impaired in Male but Not Female Endothelial NOS Knock-out Mice

Paulina Getsy, Sripriya Sundararajan, Walter May, Graham vonSchill, Dylan McLaughlin, Lisa Palmer, Stephen Lewis,

The roles of endothelial nitric oxide synthase (eNOS) in the ventilatory responses during and after a hypercapnic gas challenge (HCC, 5% CO 2 , 21% O 2 , 74% N 2 ) were assessed in freely moving female and male wild-type (WT) C57BL6 mice and eNOS knock-out (eNOS-/-) mice of ... Read more >>

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An initiative to evaluate the safety of maternal bonding in patients with SARS-CoV-2 infection.

Liviu Cojocaru, Sarah Crimmins, Sripriya Sundararajan, Katherine Goetzinger, Emad Elsamadicy, Allison Lankford, Ozhan M Turan, Sifa Turan,

<h4>Background</h4>In the last two decades, the world faced three epidemics caused by novel coronaviruses, namely, SARS-CoV in 2002, MERS-CoV in 2012, and the ongoing SARS-CoV-2 that started in late 2019. Despite a growing understanding of SARS-CoV-2 virology, epidemiology, and clinical management strategies, other aspects, such as mode of delivery, vertical ... Read more >>

J Matern Fetal Neonatal Med (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2020, :1-7]

Cited: 2 times

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Prevention of iron deficiency anemia in infants and toddlers.

Sripriya Sundararajan, Heike Rabe,

Anemia, defined as a low blood hemoglobin concentration, is a major global public health problem. Identification of anemia is crucial to public health interventions. It is estimated globally that 273 million children under 5 years of age were anemic in 2011, and about ~50% of those cases were attributable to ... Read more >>

Pediatr Res (Pediatric research)
[2021, 89(1):63-73]

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Case 3: Sudden Unexpected Collapse in a Full-term Infant.

Abigail Aghion, Alison J Falck, Sripriya Sundararajan,

Neoreviews (NeoReviews)
[2019, 20(12):e744-e747]

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Fetal exposure to mercury and lead from intrauterine blood transfusions.

Alison J Falck, Sripriya Sundararajan, Faeq Al-Mudares, Stephen A Contag, Cynthia F Bearer,

<h4>Background</h4>Mercury (Hg) and lead (Pb) exposure during childhood is associated with irreversible neurodevelopmental effects. Fetal exposure to Hg and Pb from intrauterine blood transfusion (IUBT) has not been reported.<h4>Methods</h4>Fetal exposure was estimated based on transfusion volume and metal concentration in donor packed red blood cell (PRBCs). As biomarkers to quantify ... Read more >>

Pediatr Res (Pediatric research)
[2019, 86(4):510-514]

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Impact of red blood cell transfusions on intestinal barrier function in preterm infants.

O O Ajayi, N L Davis, B Saleem, S Kapoor, A C Okogbule-Wonodi, R M Viscardi, Sripriya Sundararajan,

<h4>Objective</h4>To determine the relationships of red blood cell (RBC) transfusion and enteral feeding to changes in intestinal permeability (IP) measured by the relative intestinal uptake of lactulose (La) and rhamnose (Rh) in preterm infants <33 wk gestation.<h4>Design/methods</h4>Infants 240-326wk gestation received La/Rh solution enterally on study days 1, 8 and 15.Urinary La/Rh ... Read more >>

J Neonatal Perinatal Med (Journal of neonatal-perinatal medicine)
[2019, 12(1):95-101]

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Neonatal Gabapentin Withdrawal Syndrome.

Melisa Carrasco, Sanjai C Rao, Cynthia F Bearer, Sripriya Sundararajan,

<h4>Introduction</h4>Gabapentin, an anticonvulsant, neuroleptic, and pain medication, is widely used in both adults and children for management of epilepsy, bipolar illness, and neuropathic pain. Gabapentin use has also been recommended for hyperemesis gravidarum and restless leg syndrome in pregnant mothers.<h4>Objective</h4>Although gabapentin use is deemed safe during pregnancy, no clinical reports ... Read more >>

Pediatr Neurol (Pediatric neurology)
[2015, 53(5):445-447]

Cited: 10 times

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The cytokines of pulmonary fibrosis: Much learned, much more to learn.

Irina G Luzina, Nevins W Todd, Sripriya Sundararajan, Sergei P Atamas,

Organ fibrosis, the result of exaggerated, persistent, and often irreversible accumulation of extracellular matrix, complicates numerous diseases in all organs and tissues and has particularly serious consequences in the lungs. Abnormally accumulating scar tissue both replaces normally functioning parenchyma and distorts the architecture of unaffected tissue. In the lungs, the ... Read more >>

Cytokine (Cytokine)
[2015, 74(1):88-100]

Cited: 36 times

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Effects of non-leukocyte-reduced and leukocyte-reduced packed red blood cell transfusions on oxygenation of rat spinotrapezius muscle.

Sripriya Sundararajan, Sami C Dodhy, Roland N Pittman, Stephen J Lewis,

Leukoreduction of blood used for transfusion alleviates febrile transfusion reactions, graft versus host disease and alloimmunization to leukocyte antigen. However, the actual clinical benefit of leukoreduction in terms of microcirculatory tissue O2 delivery after packed red blood cell (pRBC) transfusion has not been investigated. As such, the aim of this ... Read more >>

Microvasc Res (Microvascular research)
[2014, 91:30-36]

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Sickle cell disease does not decrease pulmonary nitric oxide.

Sripriya Sundararajan, Benjamin Gaston,

J Pediatr (The Journal of pediatrics)
[2012, 160(1):6-7]

Cited: 1 time

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