Full Text Journal Articles by
Author Soichiro Ishihara

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Systemic single administration of anti-inflammatory microRNA 146a-5p loaded in polymeric nanomedicines with active targetability attenuates neointimal hyperplasia by controlling inflammation in injured arteries in a rat model.

Masaya Sano, Daisuke Akagi, Mitsuru Naito, Katsuyuki Hoshina, Kanjiro Miyata, Kazunori Kataoka, Soichiro Ishihara,

Neointimal hyperplasia (NIH) after revascularization is a key unsolved clinical problem. Various studies have shown that attenuation of the acute inflammatory response on the vascular wall can prevent NIH. MicroRNA146a-5p (miR146a-5p) has been reported to show anti-inflammatory effects by inhibiting the NF-κB pathway, a well-known key player of inflammation of ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2022, 36(9):e22486]

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Diverting ileostomy is a risk factor for renal impairment during CAPOX therapy.

Kazuaki Okamoto, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Soichiro Ishihara,

<h4>Purpose</h4>Temporary ileostomy is sometimes created after colorectal surgery and may cause renal impairment. However, the impact of ileostomy on renal function during adjuvant chemotherapy for colorectal cancer (CRC) remains unknown. The aim of the present study was to examine the effects of ileostomy on renal function during adjuvant chemotherapy.<h4>Methods</h4>We examined ... Read more >>

Int J Clin Oncol (International journal of clinical oncology)
[2022, :]

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