Full Text Journal Articles by
Author Sobia Rafiq


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Sporadic Early Onset Colorectal Cancer in Pakistan: a Case- Control Analysis of Microsatellite Instability.

Sabeehuddin Siddique, Kanwal Tariq, Sobia Rafiq, Ahmed Raheem, Rashida Ahmed, Munira Shabbir-Moosajee, Kulsoom Ghias,

Early onset sporadic colorectal cancer (CRC) is a biologically and clinically distinct entity hypothesized to exhibit differences in histological features and microsatellite instability (MSI) as compared to typical onset CRC. This study compared the MSI status, mismatch repair enzyme deficiency and clinicopathological features of early onset (aged ≤45 years) with ... Read more >>

Asian Pac. J. Cancer Prev. (Asian Pacific journal of cancer prevention : APJCP)
[2016, 17(5):2587-2592]

Cited: 1 time

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Clinical features and outcome of sporadic colorectal carcinoma in young patients: a cross-sectional analysis from a developing country.

Muhammad Nauman Zahir, Eisha Mahpara Azhar, Sobia Rafiq, Kulsoom Ghias, Munira Shabbir-Moosajee,

Background. Early onset colorectal carcinoma (CRC) is rare and has been hypothesized to be a biologically and clinically distinct entity personifying aggressive disease and worse survival. Methods. Data for 131 patients was collected by retrospective chart review. Cox proportional hazard model was used to compute prevalence ratios and 95% confidence ... Read more >>

(ISRN oncology)
[2014, 2014:461570]

Cited: 11 times

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Novel and recurrent LDLR gene mutations in Pakistani hypercholesterolemia patients.

Waqas Ahmed, Muhammad Ajmal, Ahmed Sadeque, Roslyn A Whittall, Sobia Rafiq, Wendy Putt, Athar Khawaja, Fauzia Imtiaz, Nuzhat Ahmed, Maleeha Azam, Steve E Humphries, Raheel Qamar,

The majority of patients with the autosomal dominant disorder familial hypercholesterolemia (FH) carry novel mutations in the low density lipoprotein receptor (LDLR) that is involved in cholesterol regulation. In different populations the spectrum of mutations identified is quite different and to date there have been only a few reports of ... Read more >>

Mol. Biol. Rep. (Molecular biology reports)
[2012, 39(7):7365-7372]

Cited: 4 times

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