Full Text Journal Articles by
Author Smruti Ranjan Mishra

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An in vivo and in silico analysis of novel variation in TMBIM6 gene affecting cardiopulmonary traits of Indian goats.

Lipi Lekha Swain, Chinmoy Mishra, Siddhant Sekhar Sahoo, Gangadhar Nayak, Sukanta Kumar Pradhan, Smruti Ranjan Mishra, Mahesh Dige,

Transmembrane Bax Inhibitor Motif-containing 6 (TMBIM6) gene acts as calcium leak channel and negatively regulates autophagy and autophagosome formation. The TMBIM6 gene was amplified and searched for variation in three different goat populations (i.e. Black Bengal, Ganjam and Raighar) of Odisha state of the India. The result indicated two substitutions ... Read more >>

J. Therm. Biol. (Journal of thermal biology)
[2020, 88:102491]

Cited: 0 times

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Common variable immunodeficiency syndrome with chronic diarrhoea.

Mukesh Nasa, Smruti Ranjan Mishra, Lipika Lipi, Randhir Sud,

Common variable immunodeficiency syndrome (CVID) is a heterogeneous disorder characterised by diminished levels of IgG, IgA and/or IgM, and recurrent bacterial infections. Sinopulmonary infections are most commonly reported followed by gastrointestinal (GI) infections. GI tract represents the largest immune organ with abundance of lymphoid cells, its involvement can manifest variably ... Read more >>

BMJ Case Rep (BMJ case reports)
[2019, 12(3):]

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Expression and secretory profile of buffalo fetal fibroblasts and Wharton's jelly feeder layers.

Mehtab S Parmar, Smruti Ranjan Mishra, Anjali Somal, Sriti Pandey, G Sai Kumar, Mihir Sarkar, Vikash Chandra, G Taru Sharma,

The present study examined the comparative expression and secretory profile of vital signaling molecules in buffalo fetal fibroblasts (BFF) and Wharton's jelly (BWJ) feeder layers at different passages. Both feeder layers were expanded up to 8th passage. Signaling molecules viz. bone morphogenetic protein 4 (BMP4), fibroblast growth factor 2 (FGF2), ... Read more >>

Anim. Reprod. Sci. (Animal reproduction science)
[2017, 180:66-77]

Cited: 0 times

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Gastrointestinal Histoplasmosis: A Case Series.

Rashi Sharma, Lipika Lipi, Smeeta Gajendra, Ishani Mohapatra, Ruchika K Goel, Rajan Duggal, Smruti Ranjan Mishra, Dheeraj Gautam,

Histoplasmosis is an invasive mycosis caused by inhalation of the spores of dimorphic fungi Histoplasma capsulatum. The disease manifests in the lung as acute or chronic pulmonary histoplasmosis and in severe cases gets disseminated in multiple organs like skin, adrenal gland, central nervous system, lymph node, liver, spleen, bone marrow, ... Read more >>

Int. J. Surg. Pathol. (International journal of surgical pathology)
[2017, 25(7):592-598]

Cited: 3 times

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Early primary prophylaxis with beta-blockers does not prevent the growth of small esophageal varices in cirrhosis: a randomized controlled trial.

Shiv Kumar Sarin, Smruti Ranjan Mishra, Praveen Sharma, Barjesh Chander Sharma, Ashish Kumar,

The efficacy of portal pressure reduction by beta-blockers and the utility of serial hepatic venous pressure gradient (HVPG) measurements for the management of small (≤5 mm) esophageal varices in patients of cirrhosis are not clear.The study had the following aims: to study (1) the effect of propranolol on the growth of ... Read more >>

Hepatol Int (Hepatology international)
[2013, 7(1):248-256]

Cited: 14 times

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Liver and spleen stiffness in patients with extrahepatic portal vein obstruction.

Praveen Sharma, Smruti Ranjan Mishra, Manoj Kumar, Barjesh Chander Sharma, Shiv Kumar Sarin,

PURPOSE: To evaluate liver stiffness (LS) and spleen stiffness (SS) in patients with extrahepatic portal vein obstruction (EHPVO). MATERIALS AND METHODS: Institutional research board approval and informed consent were obtained. LS and SS were measured in 65 consecutive patients with EHPVO. Patients underwent endoscopy, liver biopsy, liver function tests, abdominal ... Read more >>

Radiology (Radiology)
[2012, 263(3):893-899]

Cited: 27 times

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Primary prophylaxis of gastric variceal bleeding comparing cyanoacrylate injection and beta-blockers: a randomized controlled trial.

Smruti Ranjan Mishra, Barjesh Chander Sharma, Ashish Kumar, Shiv Kumar Sarin,

BACKGROUND & AIMS: Gastric variceal bleeding is severe and is associated with high mortality. We compared the efficacy of cyanoacrylate injection and beta-blockers in primary prophylaxis of gastric variceal bleeding. METHODS: Cirrhotics with large gastroesophageal varices type 2 with eradicated esophageal varices or large isolated gastric varix type 1, who ... Read more >>

J. Hepatol. (Journal of hepatology)
[2011, 54(6):1161-1167]

Cited: 49 times

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Equal efficacy of endoscopic variceal ligation and propranolol in preventing variceal bleeding in patients with noncirrhotic portal hypertension.

Shiv Kumar Sarin, Nitin Gupta, Sanjeev Kumar Jha, Amit Agrawal, Smruti Ranjan Mishra, Barjesh Chander Sharma, Ashish Kumar,

BACKGROUND & AIMS: Variceal bleeding increases morbidity and mortality among patients with noncirrhotic portal hypertension (NCPH). Blockers of β-adrenergic receptor signaling and endoscopic variceal ligation (EVL) have been used to prevent recurrence of bleeding, based on data from cirrhotic patients. We compared the efficacy and safety of the β-blocker propranolol ... Read more >>

Gastroenterology (Gastroenterology)
[2010, 139(4):1238-1245]

Cited: 31 times

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Endoscopic cyanoacrylate injection versus beta-blocker for secondary prophylaxis of gastric variceal bleed: a randomised controlled trial.

Smruti Ranjan Mishra, Barjesh Chander Sharma, Ashish Kumar, Shiv Kumar Sarin,

BACKGROUND AND AIMS: Bleeding from gastric varices is often severe and difficult to manage. Endoscopic injection of gastric varices with cyanoacrylate is effective in prevention of rebleeding. The efficacy of beta-blockers in secondary prophylaxis of gastric variceal bleed has not been well studied. A comparison of the efficacy of beta-blocker ... Read more >>

Gut (Gut)
[2010, 59(6):729-735]

Cited: 45 times

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Clinical, laboratory, and hemodynamic parameters in portal hypertensive gastropathy: a study of 254 cirrhotics.

Ashish Kumar, Smruti Ranjan Mishra, Praveen Sharma, Barjesh Chander Sharma, Shiv Kumar Sarin,

BACKGROUND: Portal hypertensive gastropathy (PHG) is the most common gastric mucosal injury in patients with liver cirrhosis. It is a cause of both acute and chronic upper gastrointestinal bleeding even in the absence of esophageal or gastric varices. The pathogenesis of PHG is unclear. It is not known whether PHG ... Read more >>

J. Clin. Gastroenterol. (Journal of clinical gastroenterology)
[2010, 44(4):294-300]

Cited: 20 times

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