Full Text Journal Articles by
Author Siyu Gu

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Cryptic t(15;17) acute promyelocytic leukemia with a karyotype of add(11)(p15) and t(13,20)- A case report with a literature review.

Siyu Gu, Jie Zi, Jinlong Ma, Zheng Ge,

Most acute promyelocytic leukemia (APL) are characterized by reciprocal translocations t(15;17)(q22;21), which results in the fusion of PML gene at 15q22 with RARα gene at 17q21. However, several complex variant translocations also have been reported. Here we report a 62-year-old man with typical morphology and clinical features of APL with ... Read more >>

Bosn J Basic Med Sci (Bosnian journal of basic medical sciences)
[2020, :]

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Elevated TNFRSF4 gene expression is a predictor of poor prognosis in non-M3 acute myeloid leukemia.

Siyu Gu, Jie Zi, Qi Han, Chunhua Song, Zheng Ge,

Background:We used bioinformatic tools to dichotomize 157 non-M3 AML patients from the TCGA dataset based on the presence or absence of TP53 mutations, and screened out a key gene related to TP53 mutation for future analysis. Methods:DEGs were analyzed by R package "DESeq2" and then run GSEA, GO enrichment, KEGG ... Read more >>

Cancer Cell Int (Cancer cell international)
[2020, 20:146]

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Tillage practices and residue management manipulate soil bacterial and fungal assembly and co-occurrence network patterns in maize agroecosystem

Wei Yang, Yupeng Guan, Cheng Zhai, Lin Du, Yanxiang Wu, Jing Wang, Yuhang Li, Jiayu Yang, Jinxi He, Siyu Gu,

Abstract The authors have withdrawn this preprint due to author disagreement. ... Read more >>

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Response of Fungal Communities and Co-occurrence Network Patterns to Compost Amendment in Black Soil of Northeast China.

Wei Yang, Xuyuan Jing, Yupeng Guan, Cheng Zhai, Tao Wang, Dengyu Shi, Wenpeng Sun, Siyu Gu,

In agroecosystems, fungi not only attract attention as crop pathogens, but also play crucial roles in nutrient cycling as decomposers and arbuscular mycorrhizal mutualists. Consequently soil fungi strongly influence agroecosystem function, and are conspicuously influenced by agricultural practices. We examined the effects of four compost rates (0, 11.25, 22.5, and ... Read more >>

(Frontiers in microbiology)
[2019, 10:1562]

Cited: 1 time

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Loss of PDZK1 expression activates PI3K/AKT signaling via PTEN phosphorylation in gastric cancer.

Chunjuan Zhao, Tao Tao, Longyan Yang, Qiong Qin, Ying Wang, Hua Liu, Ran Song, Xiaomei Yang, Qiqi Wang, Siyu Gu, Ying Xiong, Dong Zhao, Songlin Wang, Duiping Feng, Wen G Jiang, Jun Zhang, Junqi He,

Phosphorylation of PTEN plays an important role in carcinogenesis and progression of gastric cancer. However, the underlying mechanism of PTEN phosphorylation regulation remains largely elusive. In the present study, PDZK1 was identified as a novel binding protein of PTEN by association of PTEN through its carboxyl terminus and PDZ domains ... Read more >>

Cancer Lett. (Cancer letters)
[2019, 453:107-121]

Cited: 3 times

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HPV16 E6 promotes cervical cancer cell migration and invasion by downregulation of NHERF1.

Qiqi Wang, Ran Song, Chunjuan Zhao, Hua Liu, Ying Yang, Siyu Gu, Duiping Feng, Junqi He,

HPV16 is the predominant type of HPV causing invasive cervical cancer. However, the underlying molecular mechanism of the unparalleled carcinogenic power of HPV16 compared to other types of high-risk (HR)-HPV including HPV18 remains elusive. The PDZ binding motif (PBM) of high-risk HPV E6 plays an important role in neoplasia and ... Read more >>

Int. J. Cancer (International journal of cancer)
[2019, 144(7):1619-1632]

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Mechanism and Treatment of Rituximab Resistance in Diffuse Large Bcell Lymphoma.

Linqing Zou, Guoqi Song, Siyu Gu, Lingling Kong, Shiqi Sun, Li Yang, William C Cho,

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype B non-Hodgkin lymphoma in adults. After rituximab being introduced to treat DLBCL, the current first-line treatment is R-CHOP regimen. This regimen greatly improves patient's prognosis, however, relapsed or refractory cases are commonly seen, mainly due to the resistance to rituximab. ... Read more >>

Curr Cancer Drug Targets (Current cancer drug targets)
[2019, 19(9):681-687]

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NHERF1 inhibits beta-catenin-mediated proliferation of cervical cancer cells through suppression of alpha-actinin-4 expression.

Qiqi Wang, Qiong Qin, Ran Song, Chunjuan Zhao, Hua Liu, Ying Yang, Siyu Gu, Deshan Zhou, Junqi He,

Cervical cancer is one of the most lethal types of cancer in female. Aberrant activation of Wnt/β-catenin signaling pathway has been found to be involved in cervical cancer development and progression, whereas the underlying molecular mechanisms remain poorly understood. The present study showed that NHERF1 was a novel gene associated ... Read more >>

Cell Death Dis (Cell death & disease)
[2018, 9(6):668]

Cited: 4 times

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Long noncoding RNA identification in lymphoma.

Gu Siyu, Zou Linqing, Kong Linling, Liu Hong, Song Guoqi, William C Cho,

It has been found that long noncoding RNA (lncRNA) are abnormally expressed in lymphoma and play an important role in its pathogenesis. Through the detection and analysis of lncRNA, it was found that lncRNA could be used as an excellent biomarker for the diagnosis and prognosis of cancer. In lymphoma, ... Read more >>

Future Oncol (Future oncology (London, England))
[2017, 13(27):2479-2487]

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Compost Addition Enhanced Hyphal Growth and Sporulation of Arbuscular Mycorrhizal Fungi without Affecting Their Community Composition in the Soil.

Wei Yang, Siyu Gu, Ying Xin, Ayodeji Bello, Wenpeng Sun, Xiuhong Xu,

Arbuscular mycorrhizal (AM) fungi form symbiotic associations with most crop plant species in agricultural ecosystems, and are conspicuously influenced by various agricultural practices. To understand the impact of compost addition on AM fungi, we examined effect of four compost rates (0, 11.25, 22.5, and 45 Mg/ha) on the abundance and ... Read more >>

(Frontiers in microbiology)
[2018, 9:169]

Cited: 3 times

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Temporal variations of soil microbial community under compost addition in black soil of Northeast China

Wei Yang, Cheng Chen, Lijun Cheng, Siyu Gu, Xiaochun Wang, Xiuhong Xu, Yu Hu, Yuting Guo,

Soil microorganisms play crucial roles in regulating dynamics of organic matter in agroecosystem, and are conspicuously influenced by agricultural practices. To reveal the effect of compost addition on soil microorganisms, we examined the soil properties, soil microbial biomass, activity, diversity and communities at soybean seedling, flowering and mature stage in ... Read more >>

(Applied soil ecology : a section of Agriculture, Ecosystems & Environment)
[2017, 121:214-222]

Cited: 4 times

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The role of Capon in multiple myeloma.

Yaodong Shen, Haiyan Liu, Siyu Gu, Ziwei Wei, Hong Liu,

Capon is a ligand protein of nitric oxide synthase 1. Recently, studies have shown that Capon is involved in the development of tumors. It is independent of the regulation of nitric oxide synthase 1 in this process. At the same time, studies have found that nitric oxide synthase 1 is ... Read more >>

Tumour Biol. (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine)
[2017, 39(7):1010428317713674]

Cited: 1 time

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Global Analysis of miRNA-mRNA Interaction Network in Breast Cancer with Brain Metastasis.

Zhixin Li, Zhiqiang Peng, Siyu Gu, Junfang Zheng, Duiping Feng, Qiong Qin, Junqi He,

MicroRNAs (miRNAs) have been linked to a number of cancer types including breast cancer. The rate of brain metastases is 10-30% in patients with advanced breast cancer which is associated with poor prognosis. The potential application of miRNAs in the diagnostics and therapeutics of breast cancer with brain metastasis is ... Read more >>

Anticancer Res. (Anticancer research)
[2017, 37(8):4455-4468]

Cited: 7 times

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