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Kidney health for everyone everywhere-From prevention to detection and equitable access to care.

Philip K-T Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston W-S Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

Nephrology (Carlton) (Nephrology (Carlton, Vic.))
[2020, 25(3):195-201]

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Kidney Health for Everyone Everywhere-From Prevention to Detection and Equitable Access to Care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

The global burden of chronic kidney disease (CKD) is increasing with a projection of becoming the fifth leading cause of years of life lost globally by 2040. CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of the entire annual ... Read more >>

J Ren Care (Journal of renal care)
[2020, 46(1):4-12]

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Kidney health for everyone everywhere - from prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh,

The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of ... Read more >>

Clin. Nephrol. (Clinical nephrology)
[2020, 93(3):111-122]

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Kidney health for everyone everywhere-from prevention to detection and equitable access to care.

Philip Kam-Tao Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston Wing-Shing Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

Kidney Int. (Kidney international)
[2020, 97(2):226-232]

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Kidney health for everyone, everywhere: from prevention to detection and equitable access to care.

Philip K-T Li, Guillermo Garcia-Garcia, Siu-Fai Lui, Sharon Andreoli, Winston W-S Fung, Anne Hradsky, Latha Kumaraswami, Vassilios Liakopoulos, Ziyoda Rakhimova, Gamal Saadi, Luisa Strani, Ifeoma Ulasi, Kamyar Kalantar-Zadeh, ,

Intern Med J (Internal medicine journal)
[2020, 50(2):145-150]

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Patient experience and satisfaction with inpatient service: development of short form survey instrument measuring the core aspect of inpatient experience.

Eliza L Y Wong, Angela Coulter, Paul Hewitson, Annie W L Cheung, Carrie H K Yam, Siu Fai Lui, Wilson W S Tam, Eng-Kiong Yeoh,

Patient experience reflects quality of care from the patients' perspective; therefore, patients' experiences are important data in the evaluation of the quality of health services. The development of an abbreviated, reliable and valid instrument for measuring inpatients' experience would reflect the key aspect of inpatient care from patients' perspective as ... Read more >>

PLoS ONE (PloS one)
[2015, 10(4):e0122299]

Cited: 5 times

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Heart failure with preserved or reduced ejection fraction in patients treated with peritoneal dialysis.

Angela Yee-Moon Wang, Mei Wang, Christopher Wai-Kei Lam, Iris Hiu-Shuen Chan, Siu-Fai Lui, John E Sanderson,

BACKGROUND: Heart failure is one of the most frequent complications in dialysis patients. However, little is known of the significance of the entity "heart failure with preserved ejection fraction" (HFPEF) in this population. This study aimed to determine the prevalence, clinical profiles, and long-term outcomes of peritoneal dialysis patients with ... Read more >>

Am. J. Kidney Dis. (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2013, 61(6):975-983]

Cited: 11 times

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Rituximab use in the catastrophic antiphospholipid syndrome: descriptive analysis of the CAPS registry patients receiving rituximab.

Horacio Berman, Ignasi Rodríguez-Pintó, Ricard Cervera, Nathalie Morel, Nathalie Costedoat-Chalumeau, Doruk Erkan, Yehuda Shoenfeld, Gerard Espinosa, ,

The catastrophic variant of the antiphospholipid syndrome (APS) is characterized by thrombosis in multiple organs developing over a short period of time. First-line treatment for the catastrophic APS is the combination of anticoagulation plus corticosteroids plus plasma exchange and/or intravenous immunoglobulin. Despite this regimen, the mortality remains high and new ... Read more >>

Autoimmun Rev (Autoimmunity reviews)
[2013, 12(11):1085-1090]

Cited: 70 times

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Heart failure in long-term peritoneal dialysis patients: a 4-year prospective analysis.

Angela Yee-Moon Wang, Mei Wang, Christopher Wai-Kei Lam, Iris Hiu-Shuen Chan, Siu-Fai Lui, John E Sanderson,

BACKGROUND AND OBJECTIVES: Heart failure occurs frequently in end-stage renal disease patients. However, there are no prospective, longitudinal follow-up data on its prevalence, severity, and risk factors in long-term peritoneal dialysis (PD) patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A prospective observational study was conducted in 220 long-term PD patients followed ... Read more >>

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2011, 6(4):805-812]

Cited: 29 times

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Prognostic value of plasma myeloperoxidase in ESRD patients.

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, Iris Hiu-Shuen Chan, Mei Wang, Siu-Fai Lui, John E Sanderson,

BACKGROUND: Myeloperoxidase (MPO) has been suggested to have a role in atherosclerosis through its strong oxidative capacity. We hypothesized that MPO level may predict clinical outcomes in patients with end-stage renal disease receiving long-term peritoneal dialysis (PD) therapy. STUDY DESIGN: Prospective cohort study. SETTING & PARTICIPANTS: 236 long-term PD patients ... Read more >>

Am. J. Kidney Dis. (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2010, 56(5):937-946]

Cited: 10 times

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Sudden cardiac death in end-stage renal disease patients: a 5-year prospective analysis.

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, Iris Hiu-Shuen Chan, Mei Wang, Siu-Fai Lui, John E Sanderson,

End-stage renal disease patients experience a high incidence of sudden cardiac death. We performed a 5-year prospective study in 230 end-stage renal disease patients, aiming to determine the role of echocardiography and the additional value of serum biomarkers in predicting sudden cardiac death. During follow-up, 24% of all deaths were ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2010, 56(2):210-216]

Cited: 72 times

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Handgrip strength, but not other nutrition parameters, predicts circulatory congestion in peritoneal dialysis patients.

Angela Yee-Moon Wang, John E Sanderson, Mandy Man-Mei Sea, Mei Wang, Christopher Wai-Kei Lam, Iris Hiu-Shuen Chan, Siu-Fai Lui, Jean Woo,

BACKGROUND: Handgrip strength (HGS) is a marker of lean muscle mass. This study aims to test the hypothesis that a low HGS reflects a diseased cardiac status and predicts future risk of circulatory congestion in chronic peritoneal dialysis (PD) patients. METHODS: Two hundred and eighteen chronic PD patients were prospectively ... Read more >>

Nephrol. Dial. Transplant. (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2010, 25(10):3372-3379]

Cited: 6 times

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Catastrophic antiphospholipid syndrome (CAPS): update from the 'CAPS Registry'.

R Cervera, ,

Although less than 1% of patients with the antiphospholipid syndrome (APS) develop the catastrophic variant, its potentially lethal outcome emphasizes its importance in clinical medicine today. However, the rarity of this variant makes it extraordinarily difficult to study in any systematic way. In order to put together all of the ... Read more >>

Lupus (Lupus)
[2010, 19(4):412-418]

Cited: 36 times

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Long-term mortality and cardiovascular risk stratification of peritoneal dialysis patients using a combination of inflammation and calcification markers.

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, Iris Hiu-Shuen Chan, Mei Wang, Siu-Fai Lui, John E Sanderson,

BACKGROUND: It remains unknown whether a composite of inflammation and calcification markers provides better mortality and cardiovascular risk stratification in chronic peritoneal dialysis (PD) patients. METHODS: We performed a 4-year prospective follow-up study in 231 chronic PD patients from a single regional dialysis centre in Hong Kong. Valvular calcification was ... Read more >>

Nephrol. Dial. Transplant. (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2009, 24(12):3826-3833]

Cited: 22 times

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Diagnostic potential of serum biomarkers for left ventricular abnormalities in chronic peritoneal dialysis patients.

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, Mei Wang, Iris Hiu-Shuen Chan, Siu-Fai Lui, Yan Zhang, John E Sanderson,

BACKGROUND: N-terminal-pro-brain natriuretic peptide, cardiac troponin T (cTnT) and high sensitivity C-reactive protein (hs-CRP) have been shown to predict mortality and cardiovascular outcomes in end-stage renal disease patients. However, it is not known which biomarkers have the strongest diagnostic potential for left ventricular (LV) abnormalities in chronic peritoneal dialysis (PD) ... Read more >>

Nephrol. Dial. Transplant. (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2009, 24(6):1962-1969]

Cited: 31 times

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Energy intake and expenditure profile in chronic peritoneal dialysis patients complicated with circulatory congestion.

Angela Yee-Moon Wang, Mandy Man-Mei Sea, Nelson Tang, Christopher Wai-kei Lam, Iris Hiu-Shuen Chan, Siu-Fai Lui, John E Sanderson, Jean Woo,

BACKGROUND: Circulatory congestion is an adverse predictor of mortality in peritoneal dialysis (PD) patients. OBJECTIVE: This study evaluated the nutritional status, energy intake, and expenditure profile of PD patients with and without previous circulatory congestion. DESIGN: We conducted a cross-sectional study in 244 PD patients, of whom 92 had previous ... Read more >>

Am. J. Clin. Nutr. (The American journal of clinical nutrition)
[2009, 90(5):1179-1184]

Cited: 10 times

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Is valvular calcification a part of the missing link between residual kidney function and cardiac hypertrophy in peritoneal dialysis patients?

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, Mei Wang, Iris Hiu-Shuen Chan, Siu-Fai Lui, John E Sanderson,

BACKGROUND AND OBJECTIVES: Residual renal function (RRF) predicts survival and shows an important inverse relation with cardiac hypertrophy in peritoneal dialysis (PD) patients. We hypothesized that valvular calcification and the calcification milieu may be part of the process linking loss of RRF and cardiac hypertrophy. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: ... Read more >>

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2009, 4(10):1629-1636]

Cited: 10 times

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Catastrophic antiphospholipid syndrome (CAPS): descriptive analysis of a series of 280 patients from the "CAPS Registry".

Ricard Cervera, Silvia Bucciarelli, Miguel A Plasín, José A Gómez-Puerta, Joan Plaza, Guillermo Pons-Estel, Yehuda Shoenfeld, Miguel Ingelmo, Gerard Espinos, ,

OBJECTIVE: To describe the clinical and laboratory features, as well as the precipitating factors, treatment and outcome of patients with catastrophic antiphospholipid syndrome (APS). METHODS: We analyzed the 280 patients included until September 2008 in the website based international registry of patients with catastrophic APS ("CAPS Registry") (http://www.med.ub.es/MIMMUN/FORUM/CAPS.HTM). RESULTS: The ... Read more >>

J. Autoimmun. (Journal of autoimmunity)
[2009, 32(3-4):240-245]

Cited: 103 times

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Serum 25-hydroxyvitamin D status and cardiovascular outcomes in chronic peritoneal dialysis patients: a 3-y prospective cohort study.

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, John E Sanderson, Mei Wang, Iris Hiu-Shuen Chan, Siu-Fai Lui, Mandy Man-Mei Sea, Jean Woo,

Patients with kidney disease are at high risk of developing 25-hydroxyvitamin D [25(OH)D] deficiency.We studied the association between serum 25(OH)D status and clinical outcomes of chronic peritoneal dialysis patients.We measured serum 25(OH)D concentrations in 230 prevalent peritoneal dialysis patients and then followed these patients prospectively for 3 y or until ... Read more >>

Am. J. Clin. Nutr. (The American journal of clinical nutrition)
[2008, 87(6):1631-1638]

Cited: 72 times

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Prognostic value of cardiac troponin T is independent of inflammation, residual renal function, and cardiac hypertrophy and dysfunction in peritoneal dialysis patients.

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, Mei Wang, Iris Hiu-Shuen Chan, William B Goggins, Cheuk-Man Yu, Siu-Fai Lui, John E Sanderson,

BACKGROUND:We investigated whether cardiac troponin T (cTnT) independently predicted outcome and added prognostic value over other clinical risk predictors in chronic peritoneal dialysis (PD) with end-stage renal disease. METHODS:Baseline cTnT, echocardiography, indices of dialysis adequacy, and biochemical characteristics were assessed in 238 chronic PD patients who were followed prospectively for ... Read more >>

Clin. Chem. (Clinical chemistry)
[2007, 53(5):882-889]

Cited: 32 times

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Nutrient intake during peritoneal dialysis at the Prince of Wales Hospital in Hong Kong.

Angela Yee-Moon Wang, Mandy Man-Mei Sea, Kenway Ng, Mandy Kwan, Siu-Fai Lui, Jean Woo,

BACKGROUND: Individuals undergoing peritoneal dialysis are at increased risk of developing cardiac disease and malnutrition. STUDY DESIGN: A cross-sectional survey. SETTINGS AND PARTICIPANTS: 249 Chinese continuous ambulatory peritoneal dialysis (CAPD) patients were recruited from the Prince of Wales Hospital in Hong Kong. Another 249 age- and sex-matched controls were recruited ... Read more >>

Am. J. Kidney Dis. (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2007, 49(5):682-692]

Cited: 11 times

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Prevalence and implications of isolated microscopic hematuria in asymptomatic Chinese pregnant women.

Cheuk-Chun Szeto, Ka-Fai To, Fernand Mac-Moune Lai, Kai-Ming Chow, Wing-Hung Tam, Kwok-Yi Chung, Chi-Bon Leung, Siu-Fai Lui, Philip Kam-Tao Li, Tze-Kin Lau,

BACKGROUND: IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. However, the actual prevalence of microscopic hematuria and IgAN is unknown in the Chinese population. METHODS: We screened 7,828 consecutive pregnant women for microscopic hematuria in the antenatal clinic of a tertiary referral center. Persistent microscopic hematuria was defined ... Read more >>

Nephron Clin Pract (Nephron. Clinical practice)
[2007, 105(4):c147-52]

Cited: 2 times

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N-terminal pro-brain natriuretic peptide: an independent risk predictor of cardiovascular congestion, mortality, and adverse cardiovascular outcomes in chronic peritoneal dialysis patients.

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, Cheuk-Man Yu, Mei Wang, Iris Hiu-Shuen Chan, Yan Zhang, Siu-Fai Lui, John E Sanderson,

This study was performed to determine whether the N-terminal pro-brain natriuretic peptide (NT-pro-BNP) is a useful biomarker in predicting cardiovascular congestion, mortality, and cardiovascular death and event in chronic peritoneal dialysis (PD) patients. A prospective cohort study was conducted in 230 chronic PD patients in a dialysis unit of a ... Read more >>

J. Am. Soc. Nephrol. (Journal of the American Society of Nephrology : JASN)
[2007, 18(1):321-330]

Cited: 59 times

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Body mass index as a predictive factor for long-term renal transplant outcomes in Asians.

Kai Ming Chow, Cheuk Chun Szeto, Chi Bon Leung, Siu Fai Lui, Yuen Fan Tong, Philip Kam-Tao Li,

BACKGROUND: There is substantial evidence that renal transplant recipients with obesity or body mass index >30 kg/m(2) have increased risk of graft loss. However, few data exist for Asian population; clinicians have to rely upon indirect evidence by extrapolating the results from Caucasians to Asian recipients. STUDY: Using data from ... Read more >>

Clin Transplant (Clinical transplantation)
[2006, 20(5):582-589]

Cited: 8 times

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Circulating soluble vascular cell adhesion molecule 1: relationships with residual renal function, cardiac hypertrophy, and outcome of peritoneal dialysis patients.

Angela Yee-Moon Wang, Christopher Wai-Kei Lam, Mei Wang, Jean Woo, Iris Hiu-Shuen Chan, Siu-Fai Lui, John E Sanderson, Philip Kam-Tao Li,

BACKGROUND:Vascular cell adhesion molecule 1 (VCAM-1) is involved in leukocyte-endothelial cell interaction and has a pivotal role in inflammation. Whether it contributes to excessive mortality in dialysis patients remains uncertain. In this study, we examined circulating soluble VCAM-1 (sVCAM-1) in relation to different clinical and biochemical parameters, as well as ... Read more >>

Am. J. Kidney Dis. (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2005, 45(4):715-729]

Cited: 37 times

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