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Author Siti Syariah Mamat

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Antiulcer activity of methanol-chloroform extract of Channa striatus fillet.

Ahmad Khusairi Azemi, Mohd Hafiz Abd Rahim, Siti Syariah Mamat, Abdul Manan Mat Jais, Zainul Amiruddin Zakaria,

Channa striatus (Haruan) is Malaysian freshwater fish that is traditionally used to treat ailments related to wound and also ulcers. The aimed of the present study was to determine the mechanisms of anti-ulcer activity of chloroform: methanol extract of C. striatus fillet (CMCS) in rats. The antiulcer profile of CMCS, ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(1):143-151]

Cited: 0 times

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Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: involvement of the antioxidant mechanisms.

Zainul Amiruddin Zakaria, Farhana Yahya, Siti Syariah Mamat, Nur Diyana Mahmood, Nurhafizah Mohtarrudin, Muhammad Taher, Siti Selina Abdul Hamid, Lay Kek Teh, Mohd Zaki Salleh,

<h4>Background</h4>Methanol extract of Bauhinia purpurea L. (family Fabaceae) (MEBP) possesses high antioxidant and anti-inflammatory activities and recently reported to exert hepatoprotection against paracetamol (PCM)-induced liver injury in rats. In an attempt to identify the hepatoprotective bioactive compounds in MEBP, the extract was prepared in different partitions and subjected to the ... Read more >>

BMC Complement Altern Med (BMC complementary and alternative medicine)
[2016, 16:175]

Cited: 3 times

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Anti-ulcer activity of the aqueous extract of Melastoma malabathricum L. leaf in rats.

Wan-Noraziemah Wan Zainulddin, Zalina Zabidi, Farah Hidayah Kamisan, Farhana Yahya, Noor Aisyah Ismail, Nor Shafawati Nor Shamsahal Din, Siti Syariah Mamat, Hadijah Hassan, Norhafizah Mohtarrudin, Zainul Amiruddin Zakaria,

Melastoma malabathricum L. Smith (Melastomaceae) has been used in the Malay traditional culture to treat ulcer-based ailments.The objective of the present study was to investigate the potential anti-ulcer effect of aqueous extract of M. malabathricum leaves (AEMM) using ethanol- and indomethacin-induced gastric ulcer models in rats. Rats were divided into ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(1):35-38]

Cited: 2 times

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Gastroprotective activity of chloroform extract of Muntingia calabura and Melastoma malabathricum leaves.

Zainul Amiruddin Zakaria, Amal Syahirah Nur Zainol, Adibah Sahmat, Nurul Izzah Salleh, Azfar Hizami, Nur Diyana Mahmood, Nurliana Nasir, Siti Syariah Mamat, Farah Hidayah Kamisan, Norhafizah Mohtarrudin, Siti Selina Abdul Hamid, Siti Farah Tohid, Lay Kek Teh, Mohd Zaki Salleh,

<h4>Context</h4>Muntingia calabura L. (family Muntingiaceae) and Melastoma malabathricum L. (family Melastomaceae) are traditionally used to treat gastric ulcer.<h4>Objective</h4>The present study determines the mechanisms of gastroprotective activity of the chloroform extract of leaves obtained from both the plants using several in vitro and in vivo assays.<h4>Materials and methods</h4>Phytochemical screening, HPLC analysis, ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2016, 54(5):812-826]

Cited: 3 times

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Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves.

Zainul Amiruddin Zakaria, Tavamani Balan, Siti Syariah Mamat, Norhafizah Mohtarrudin, Teh Lay Kek, Mohd Zaki Salleh,

<h4>Background</h4>Melastoma malabathricum L. (Melastomaceae) is a small shrub with various medicinal uses. The present study was carried out to determine the gastroprotective mechanisms of methanol extract of M. malabathricum leaves (MEMM) in rats.<h4>Methods</h4>The extract's mechanisms of gastroprotection (50, 250, 500 mg/kg) were studied using the pylorus-ligation in rat model wherein volume, ... Read more >>

BMC Complement Altern Med (BMC complementary and alternative medicine)
[2015, 15:135]

Cited: 6 times

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Effect of aqueous extract of Dicranopteris linearis leaves against paracetamol and carbon tetrachloride-induced liver toxicity in rats.

Noor Aisyah Ismail, Nor Syafawati Shamsahal-Din, Siti Syariah Mamat, Zalina Zabidi, Wan-Noraziemah Wan Zainulddin, Farah Hidayah Kamisan, Farhana Yahya, Norhafizah Mohtarrudin, Mohd Nasir Mohd-Desa, Zainul Amiruddin Zakaria,

The present study aimed to determine the hepatoprotective activity of Dicranopteris linearis L. (family Gleicheniaceae) leaf aqueous extract (DLAE) using two models of liver injury in rats. Rats were divided into ten groups (n=6) and received dH2O (negative control), 200 mg/kg silymarin (positive control) or DLAE (50, 250 and 500 ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2014, 27(4):831-835]

Cited: 3 times

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Effect of methanol extract of Dicranopteris linearis against carbon tetrachloride-induced acute liver injury in rats.

Farah Hidayah Kamisan, Farhana Yahya, Siti Syariah Mamat, Mohamad Fauzi Fahmi Kamarolzaman, Norhafizah Mohtarrudin, Teh Lay Kek, Mohd Zaki Salleh, Mohd Khairi Hussain, Zainul Amiruddin Zakaria,

<h4>Background</h4>Dicranopteris linearis (family Gleicheniaceae) has been reported to possess anti-inflammatory and antioxidant activities but no attempt has been made to study its hepatoprotective potential. The aim of the present study was to determine the hepatoprotective effect of methanol extracts of D. linearis (MEDL) against carbon tetrachloride (CCl4)-induced acute liver injury ... Read more >>

BMC Complement Altern Med (BMC complementary and alternative medicine)
[2014, 14:123]

Cited: 14 times

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Methanol extract of Melastoma malabathricum leaves exerted antioxidant and liver protective activity in rats.

Siti Syariah Mamat, Mohamad Fauzi Fahmi Kamarolzaman, Farhana Yahya, Nur Diyana Mahmood, Muhammad Syahmi Shahril, Krystal Feredoline Jakius, Norhafizah Mohtarrudin, Siew Mooi Ching, Deny Susanti, Muhammad Taher, Zainul Amiruddin Zakaria,

<h4>Background</h4>Melastoma malabathricum L. (Melastomaceae) is a small shrub with various medicinal uses. The present study was carried out to determine the hepatoprotective activity of methanol extract of M. malabathricum leaves (MEMM) against the paracetamol-induced liver toxicity in rats model.<h4>Methods</h4>The respective chemicals and herbal solutions (10% DMSO, 200 mg/kg silymarin or ... Read more >>

BMC Complement Altern Med (BMC complementary and alternative medicine)
[2013, 13:326]

Cited: 15 times

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Hepatoprotective activity of methanol extract of Melastoma malabathricum leaf in rats.

Farah Hidayah Kamisan, Farhana Yahya, Noor Aisyah Ismail, Syafawati Shamsahal Din, Siti Syariah Mamat, Zalina Zabidi, Wan Noraziemah Wan Zainulddin, Norhafizah Mohtarrudin, Hadijah Husain, Zuraini Ahmad, Zainul Amiruddin Zakaria,

The present study aimed to determine the hepatoprotective activity of a methanol extract of Melastoma malabathricum leaves (MEMM) using two established rat models. Ten groups of rats (n=6) were given a once-daily administration of 10% dimethyl sulfoxide (negative control), 200 mg/kg silymarin (positive control), or MEMM (50, 250, or 500 ... Read more >>

J Acupunct Meridian Stud (Journal of acupuncture and meridian studies)
[2013, 6(1):52-55]

Cited: 0 times

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