Full Text Journal Articles by
Author Silvia Triarico

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Assessment and Management of Platinum-Related Ototoxicity in Children Treated for Cancer.

Alberto Romano, Michele Antonio Capozza, Stefano Mastrangelo, Palma Maurizi, Silvia Triarico, Rolando Rolesi, Giorgio Attinà, Anna Rita Fetoni, Antonio Ruggiero,

Platinum compounds are a group of chemotherapeutic agents included in many pediatric and adult oncologic treatment protocols. The main platinum compounds are cisplatin, carboplatin, and oxaliplatin. Their use in clinical practice has greatly improved long-term survival of pediatric patients, but they also cause some toxic effects: ototoxicity, myelosuppression, nephrotoxicity, and ... Read more >>

Cancers (Basel) (Cancers)
[2020, 12(5):]

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Temozolomide and oral etoposide in children with recurrent malignant brain tumors.

Antonio Ruggiero, Anna Ariano, Silvia Triarico, Michele Antonio Capozza, Alberto Romano, Palma Maurizi, Stefano Mastrangelo, Giorgio Attinà,

Despite advances in the treatment of brain tumors, the prognosis of children with recurrent malignant brain tumors remains poor. Etoposide (VP-16), an inhibitor of nuclear enzyme deoxyribonucleic acid (DNA)-topoisomerase II, has shown activity in brain tumors. Its efficacy appears schedule dependent but, to date, the most effective schedule of administration ... Read more >>

Drugs Context (Drugs in context)
[2020, 9:]

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Multifocal infantile haemangiomatosis with hepatic involvement: two cases and treatment management.

Antonio Ruggiero, Palma Maurizi, Silvia Triarico, Michele Antonio Capozza, Stefano Mastrangelo, Giorgio Attinà,

Infantile haemangiomas (IHs) are the most common benign tumours of childhood; despite the benign histology, prognosis depends on severity of visceral involvement, with a mortality rate ranging from 50 to 90%. In this paper, we describe two infants with multifocal infantile haemangiomatosis and hepatic involvement. This condition should receive appropriate ... Read more >>

Drugs Context (Drugs in context)
[2020, 9:]

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Gynecological cancer among adolescents and young adults (AYA).

Silvia Triarico, Michele Antonio Capozza, Stefano Mastrangelo, Giorgio Attinà, Palma Maurizi, Antonio Ruggiero,

Adolescents and young adults (AYA) patients with cancer show specific biological, sociodemographic and behavioral features, with lower survival rates than younger group. Gynecologic malignancies that occur among AYA requires a multidisciplinary management and a tailored model of care, in order to enhance the early diagnosis, the adherence to the treatment, ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2020, 8(6):397]

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Neonatal pharmacology and clinical implications.

Antonio Ruggiero, Anna Ariano, Silvia Triarico, Michele Antonio Capozza, Pietro Ferrara, Giorgio Attinà,

During the neonatal period, there is physiological immaturity of organs, systems and metabolic pathways that influences the pharmacokinetics and pharmacodynamics of administered drugs, the dosage of which should be constantly amended, considering the progressive increase in weight and the maturation of the elimination pathways. In this article, we analyse the ... Read more >>

Drugs Context (Drugs in context)
[2019, 8:212608]

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Intranasal therapy with opioids for children and adolescents with cancer: results from clinical studies.

Silvia Triarico, Michele Antonio Capozza, Stefano Mastrangelo, Giorgio Attinà, Palma Maurizi, Antonio Ruggiero,

Opioids are essential for the treatment of pain, which is a serious symptom for children and adolescents affected by cancer. Intranasal opioids may be very useful for the treatment of breakthrough pain in children and adolescents with cancer, for their little invasiveness, ease of administration, rapid onset of action, and ... Read more >>

Support Care Cancer (Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer)
[2019, 27(10):3639-3645]

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Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature.

Palma Maurizi, Michele Antonio Capozza, Silvia Triarico, Maria Luisa Perrotta, Vito Briganti, Antonio Ruggiero,

BACKGROUND:Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life (mostly if multifocal) and there is a lack of standardized recommendations for the pediatric age. CASE PRESENTATION:We describe the case of a 9-year-old boy with a diagnosis of PUNLMP, who underwent to cystoscopic ... Read more >>

BMC Urol (BMC urology)
[2019, 19(1):36]

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Improving the Brain Delivery of Chemotherapeutic Drugs in Childhood Brain Tumors.

Silvia Triarico, Palma Maurizi, Stefano Mastrangelo, Giorgio Attinà, Michele Antonio Capozza, Antonio Ruggiero,

The central nervous system (CNS) may be considered as a sanctuary site, protected from systemic chemotherapy by the meninges, the cerebrospinal fluid (CSF) and the blood-brain barrier (BBB). Consequently, parenchymal and CSF exposure of most antineoplastic agents following intravenous (IV) administration is lower than systemic exposure. In this review, we ... Read more >>

Cancers (Basel) (Cancers)
[2019, 11(6):]

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Undifferentiated Embryonal Sarcoma of the Liver (UESL) in Adolescents: An Unexpected Diagnosis.

Michele A Capozza, Antonio Ruggiero, Palma Maurizi, Stefano Mastrangelo, Giorgio Attinà, Silvia Triarico, Maria Vellone, Felice Giuliante,

Definitive diagnosis of pediatric liver masses can be challenging, because clinical manifestations are nonspecific, and ultimate diagnosis may be delayed. We describe 2 patients with liver masses that initially were misdiagnosed and treated as infectious hepatic lesions. Only after histologic examination the correct diagnosis of undifferentiated embryonal sarcoma of the ... Read more >>

J. Pediatr. Hematol. Oncol. (Journal of pediatric hematology/oncology)
[2019, 41(2):e132-e134]

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Correction to: Multimodal treatment of pediatric patients with Askin's tumors: our experience.

Silvia Triarico, Giorgio Attinà, Palma Maurizi, Stefano Mastrangelo, Lorenzo Nanni, Vito Briganti, Elisa Meacci, Stefano Margaritora, Mario Balducci, Antonio Ruggiero,

[This corrects the article DOI: 10.1186/S12957-018-1434-2.]. ... Read more >>

World J Surg Oncol (World journal of surgical oncology)
[2018, 16:193]

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Multimodal treatment of pediatric patients with Askin's tumors: our experience.

Silvia Triarico, Giorgio Attinà, Palma Maurizi, Stefano Mastrangelo, Lorenzo Nanni, Vito Briganti, Elisa Meacci, Stefano Margaritora, Mario Balducci, Antonio Ruggiero,

BACKGROUND:We report our experience and outcomes about the management of Askin's tumors [AT], which are rare primitive neuroectodermal tumors (PNETs) that develop within the soft tissue of the thoracopulmonary region, typically in children and adolescents. METHODS:We retrospectively analyzed the charts of 9 patients affected by AT (aged 6-15 years), treated at ... Read more >>

World J Surg Oncol (World journal of surgical oncology)
[2018, 16(1):140]

Cited: 1 time

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Acute chemotherapy-induced nausea and vomiting in children with cancer: Still waiting for a common consensus on treatment.

Antonio Ruggiero, Daniela Rizzo, Martina Catalano, Paola Coccia, Silvia Triarico, Giorgio Attiná,

Chemotherapy-induced nausea and vomiting (CINV) is one of the most common treatment side-effects, and remains a significant concern, in children undergoing chemotherapy. Although adult patients receive chemotherapy regimens combined with appropriate standardized antiemetic treatment, children can receive markedly varying antiemetic treatments. A narrative review of CINV was performed regarding CINV ... Read more >>

J. Int. Med. Res. (The Journal of international medical research)
[2018, 46(6):2149-2156]

Cited: 2 times

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Subacute Myopericarditis Without Myocardial Infarction Treated With Intravenous Immunoglobulin in a Child With Marked Elevation of Plasma Cardiac Troponin I.

Gabriella De Rosa, Antonio Gatto, Silvia Triarico, Marco Piastra, Piero Valentini, Valentina Giorgio, Ilaria Lazzareschi, Donato Rigante,

Pediatr Emerg Care (Pediatric emergency care)
[2016, 32(8):11-12]

Cited: 0 times

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Platinum compounds in children with cancer: toxicity and clinical management.

Antonio Ruggiero, Giovanna Trombatore, Silvia Triarico, Roberta Arena, Pietro Ferrara, Maria Scalzone, Filomena Pierri, Riccardo Riccardi,

Platinum compounds are widely used in the treatment of pediatric tumors such as neuroblastoma, germ-cell tumors, osteosarcoma, retinoblastoma, hepatoblastoma, brain tumors (low-grade gliomas and medulloblastoma/PNET), and relapsed and refractory lymphomas. The three major platinum compounds (cisplatin, carboplatin, and oxaliplatin) have a similar pharmacokinetics profile and mechanism of action, but the ... Read more >>

Anticancer Drugs (Anti-cancer drugs)
[2013, 24(10):1007-1019]

Cited: 31 times

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Incidence, clinical features and management of hypersensitivity reactions to chemotherapeutic drugs in children with cancer.

Antonio Ruggiero, Silvia Triarico, Giovanna Trombatore, Andrea Battista, Fabiola Dell'acqua, Carmelo Rizzari, Riccardo Riccardi,

Hypersensitivity reactions (HSRs) may occur in children with cancer during the use of almost all chemotherapeutic drugs. HSRs may also produce a negative impact on treatment intensity and, as a consequence, worsen patients' outcome. The aim of this review is to summarize the incidence and the clinical features of HSRs ... Read more >>

Eur. J. Clin. Pharmacol. (European journal of clinical pharmacology)
[2013, 69(10):1739-1746]

Cited: 9 times

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Sexuality, pre-conception counseling and urological management of pregnancy for young women with spina bifida.

Daniela Visconti, Giuseppe Noia, Silvia Triarico, Tomasella Quattrocchi, Marcella Pellegrino, Brigida Carducci, Marco De Santis, Alessandro Caruso,

A great number of newborns with spina bifida now survive with a growing life expectancy. Support with regard to sexual issues is essential in the management of adolescents with spina bifida, who require specific knowledge of sexual problems related to their disability. Women with spina bifida are usually fertile and ... Read more >>

Eur. J. Obstet. Gynecol. Reprod. Biol. (European journal of obstetrics, gynecology, and reproductive biology)
[2012, 163(2):129-133]

Cited: 10 times

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Determinants of bone mineral density, bone mineral content, and body composition in a cohort of healthy children: influence of sex, age, puberty, and physical activity.

Emanuele Ausili, Donato Rigante, Elio Salvaggio, Benedetta Focarelli, Claudia Rendeli, Valentina Ansuini, Valentina Paolucci, Silvia Triarico, Lucilla Martini, Paolo Caradonna,

Interventions directed to the recognition of abnormal bone mineral density, bone mineral content, and body composition in the pediatric age require the definition of factors influencing bone mass acquisition during growth. We have evaluated in a cross-sectional manner by dual-energy X-ray absorptiometry the impact of sex, age, puberty, and physical ... Read more >>

Rheumatol. Int. (Rheumatology international)
[2012, 32(9):2737-2743]

Cited: 12 times

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