Full Text Journal Articles by
Author Silke Ludwig

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Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury.

Roman Meierhans, Markus Béchir, Silke Ludwig, Jutta Sommerfeld, Giovanna Brandi, Christoph Haberthür, Reto Stocker, John F Stover,

<h4>Introduction</h4>The optimal blood glucose target following severe traumatic brain injury (TBI) must be defined. Cerebral microdialysis was used to investigate the influence of arterial blood and brain glucose on cerebral glucose, lactate, pyruvate, glutamate, and calculated indices of downstream metabolism.<h4>Methods</h4>In twenty TBI patients, microdialysis catheters inserted in the edematous frontal ... Read more >>

Crit Care (Critical care (London, England))
[2010, 14(1):R13]

Cited: 42 times

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Increasing hematocrit above 28% during early resuscitative phase is not associated with decreased mortality following severe traumatic brain injury.

Carole Flückiger, Markus Béchir, Mirko Brenni, Silke Ludwig, Jutta Sommerfeld, Silvia R Cottini, Marius Keel, Reto Stocker, John F Stover,

<h4>Background</h4>To prevent iatrogenic damage, transfusions of red blood cells should be avoided. For this, specific and reliable transfusion triggers must be defined. To date, the optimal hematocrit during the initial operating room (OR) phase is still unclear in patients with severe traumatic brain injury (TBI). We hypothesized that hematocrit values ... Read more >>

Acta Neurochir (Wien) (Acta neurochirurgica)
[2010, 152(4):627-636]

Cited: 9 times

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