Full Text Journal Articles by
Author Sidra Noor

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Drug-drug interactions associated with adverse clinical outcomes and abnormal laboratory findings in patients with malaria

Sidra Noor, Mohammad Ismail, Faiza Khadim,

Abstract Background: Hospitalized patients with malaria often present with comorbidities or associated complications for which a variety of drugs are prescribed. Multiple drug therapy often leads to drug-drug interactions (DDIs). Therefore, we investigated the prevalence, levels, risk factors, clinical relevance, and monitoring parameters/management guidelines of potential DDIs (pDDIs) among inpatients ... Read more >>

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Prevalence and significance of potential drug-drug interactions among cancer patients receiving chemotherapy.

Mohammad Ismail, Sehrash Khan, Fahadullah Khan, Sidra Noor, Hira Sajid, Shazia Yar, Irum Rasheed,

BACKGROUND:Cancer patients often receive multiple drugs to maximize their therapeutic benefit, treat co-morbidities and counter the adverse effects of chemotherapy. Concomitant administration of multiple drugs increases the risk of drug interactions leading to compromised therapeutic efficacy or safety of therapy. The purpose of this study was to identify the prevalence, ... Read more >>

BMC Cancer (BMC cancer)
[2020, 20(1):335]

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Prevalence and significance of potential drug-drug interactions among cancer patients receiving chemotherapy

Mohammad Ismail, Sehrash Khan, Fahadullah Khan, Sidra Noor, Hira Sajid, Shazia Yar, Irum Rasheed,

Abstract Background: Cancer patients often receive multiple drugs to maximize their therapeutic benefit, treat co-morbidities and counter the adverse effects of chemotherapy. Concomitant administration of multiple drugs increases the risk of drug interactions leading to compromised therapeutic efficacy or safety of therapy. The purpose of this study was to identify ... Read more >>

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Drug-drug interactions in patients with malaria: a multicenter retrospective study

Sidra Noor, Mohammad Ismail,

Abstract Background: Hospitalized patients with malaria often present with comorbidities or associated complications for which a variety of drugs are prescribed. Multiple drug therapy often leads to drug-drug interactions (DDIs). Therefore, we investigated the prevalence, levels, risk factors, clinical relevance, and monitoring parameters/management guidelines of potential DDIs (pDDIs) among inpatients ... Read more >>

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Potential Drug-Drug Interactions in Patients With Urinary Tract Infections: A Contributing Factor in Patient and Medication Safety.

Sidra Noor, Mohammad Ismail, Fahadullah Khan,

Introduction: Hospitalized patients with urinary tract infections (UTIs) often present with comorbid illnesses and are subsequently prescribed multiple medications, which increases the likelihood of drug-drug interactions. Therefore, this study aimed to explore the prevalence, levels, risk factors, and clinical relevance of potential drug-drug interactions (pDDIs) in hospitalized patients with UTIs. ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2019, 10:1032]

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Potential drug-drug interactions among pneumonia patients: do these matter in clinical perspectives?

Sidra Noor, Mohammad Ismail, Zahid Ali,

BACKGROUND:Pneumonia patients are usually hospitalized due to severe nature of the disease or for the management of comorbid illnesses or associated symptoms. Such patients are prescribed with multiple medications which increase the likelihood of potential drug-drug interactions (pDDIs). Therefore, in this study the prevalence, levels (severity and documentation), predictors (risk ... Read more >>

BMC Pharmacol Toxicol (BMC pharmacology & toxicology)
[2019, 20(1):45]

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Potential drug-drug interactions in outpatient department of a tertiary care hospital in Pakistan: a cross-sectional study.

Mohammad Ismail, Sidra Noor, Umme Harram, Inamul Haq, Iqbal Haider, Faiza Khadim, Qasim Khan, Zahid Ali, Tahir Muhammad, Muhammad Asif,

BACKGROUND:Potential drug-drug interactions (pDDIs) are one of the preventable drug related problems having the risk of serious adverse events or therapeutic failure. In developing countries like Pakistan, this issue remains poorly addressed. The objective of this study was to explore prevalence of pDDIs in the Outpatient Department (OPD) of a ... Read more >>

BMC Health Serv Res (BMC health services research)
[2018, 18(1):762]

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Drug-Drug Interactions in Hepatitis Patients: Do these Interactions Matter in Clinical Perspectives?

Sidra Noor, Mohammad Ismail, Iqbal Haider, Faiza Khadim,

INTRODUCTION AND AIM:Hepatitis patients usually present with comorbidities and polypharmacy which increases risk of potential drug-drug interactions (pDDIs). We explored frequency, levels, predictors, and clinical relevance of pDDIs in hospitalized hepatitis patients. MATERIAL AND METHODS:Retrospective cohort study was used. Clinical profiles of 413 hepatitis patients were reviewed for pDDIs using ... Read more >>

Ann Hepatol (Annals of hepatology)
[2018, 17(6):1001-1011]

Cited: 1 time

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QT interval prolongation in hospitalized patients on cardiology wards: a prospective observational study.

Qasim Khan, Mohammad Ismail, Iqbal Haider, Inam Ul Haq, Sidra Noor,

Prolonged QT interval may lead to a lethal form of arrhythmia, torsades de pointes (TdP), which is associated with cardiovascular mortality. Therefore, we aimed to identify prevalence of QT interval prolongation, compare clinical characteristics of patients with normal and prolonged QT interval, and identify predictors of QT interval prolongation.A prospective ... Read more >>

Eur. J. Clin. Pharmacol. (European journal of clinical pharmacology)
[2017, 73(11):1511-1518]

Cited: 1 time

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Potential drug-drug interactions in pediatric patients admitted to intensive care unit of Khyber Teaching Hospital, Peshawar, Pakistan: A cross-sectional study.

Mohammad Ismail, Sana Aziz, Sidra Noor, Iqbal Haider, Faryal Shams, Inamul Haq, Faiza Khadim, Qasim Khan, Fahadullah Khan, Muhammad Asif,

To investigate frequencies, levels, clinical relevance and predictors of potential drug-drug interactions (pDDIs) in pediatric intensive care unit (PICU).Case notes of 411 patients were reviewed for pDDIs through Micromedex. Frequencies, levels and clinical relevance of pDDIs were reported. Logistic regression was applied to calculate the odds-ratios for predictors of pDDIs.We ... Read more >>

J Crit Care (Journal of critical care)
[2017, 40:243-250]

Cited: 3 times

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Potential drug-drug interactions in medical intensive care unit of a tertiary care hospital in Pakistan.

Mohammad Ismail, Farmanullah Khan, Sidra Noor, Iqbal Haider, Inam-Ul Haq, Zahid Ali, Zahir Shah, Mohsin Hassam,

Background Patients admitted to intensive care unit (ICU) present with severe and life-threatening illnesses. Most of them suffer from various comorbidities. They usually receive complex pharmacotherapy with large number of medicines which increase the risk of drug-drug interactions (DDIs). Objective The present report aimed to investigate prevalence and levels of ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2016, 38(5):1052-1056]

Cited: 6 times

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