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Dynamic Surface Reconstruction of Single-Atom Bimetallic Alloy under Operando Electrochemical Conditions.

Xiaokang Liu, Chengcheng Ao, Xinyi Shen, Lan Wang, Sicong Wang, Linlin Cao, Wei Zhang, Jingjing Dong, Jun Bao, Tao Ding, Lidong Zhang, Tao Yao,

The atomic-level understanding of the dynamic evolution of the surface structure of bimetallic nanoparticles under industrially relevant operando conditions provides a key guide for improving their catalytic performance. Here, we exploit operando X-ray absorption fine structure spectroscopy to determine the dynamic surface reconstruction of Cu/Au bimetallic alloy where single-atom Cu ... Read more >>

Nano Lett (Nano letters)
[2020, :]

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The value of lymphocyte count in determining the severity of COVID-19 and estimating the time for nucleic acid test results to turn negative.

Yuanchao Li, Tuoyun Yang, Sicong Wang, Junbo Zheng, Jing Zhou, Min Jiang, Tong Zhou, Yang Cao, Hongliang Wang,

Peripheral blood lymphocyte count is shown to be decreased in patients with COVID-19 in the early stage of the disease. The degree of lymphocyte count reduction is related to COVID-19 severity and could be used as an indicator to reflect the disease severity. Our aim was to investigate the value ... Read more >>

Bosn J Basic Med Sci (Bosnian journal of basic medical sciences)
[2020, :]

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The application of 6S and PDCA management strategies in the nursing of COVID-19 patients.

Wenju Wei, Sicong Wang, Hongliang Wang, Hongjia Quan,

Crit Care (Critical care (London, England))
[2020, 24(1):443]

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The value of plasma pro-enkephalin and adrenomedullin for the prediction of sepsis-associated acute kidney injury in critically ill patients.

Ruijin Liu, Xiaoya Zheng, Hongliang Wang, Sicong Wang, Kaijiang Yu, Changsong Wang,

Crit Care (Critical care (London, England))
[2020, 24(1):162]

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COVID-19 infection epidemic: the medical management strategies in Heilongjiang Province, China.

Hongliang Wang, Sicong Wang, Kaijiang Yu,

Crit Care (Critical care (London, England))
[2020, 24(1):107]

Cited: 7 times

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Cross-talk between Bcr-abl and the Thioredoxin System in Chronic Myeloid Leukaemia: Implications for CML Treatment.

Erin Clapper, Sicong Wang, Prahlad V Raninga, Giovanna Di Trapani, Kathryn F Tonissen,

Chronic myeloid leukaemia (CML) is currently treated with inhibitors of the CML specific oncoprotein, bcr-abl. While this strategy is initially successful, drug resistance can become a problem. Therefore, new targets need to be identified to ensure the disease can be appropriately managed. The thioredoxin (Trx) system, comprised of Trx, thioredoxin ... Read more >>

Antioxidants (Basel) (Antioxidants (Basel, Switzerland))
[2020, 9(3):]

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Application of low-concentration contrast agents and low-tube-voltage computed tomography to chest enhancement examinations: A multicenter prospective study.

Donghua Meng, Xiaonan Cui, Changsen Bai, Zhongwen Yu, Lei Xin, Yufei Fu, Sicong Wang, Yu Du, Zhipeng Gao, Zhaoxiang Ye,

To evaluate the influence of low-concentration contrast agents and low-tube-voltage computed tomography on chest enhancement examinations, we conducted a multicenter prospective study. A total of 216 inpatients enrolled from 12 different hospitals were randomly divided into four groups: A: voltage, 120 kVp; iohexol, 350 mgI/mL; B: voltage, 100 kVp, iohexol, ... Read more >>

Sci Prog (Science progress)
[2020, 103(1):36850419892193]

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Lactate up-regulates the expression of PD-L1 in kidney and causes immunosuppression in septic Acute Renal Injury.

Jingjing Xu, Xiaohui Ma, Kaili Yu, Ruitao Wang, Sicong Wang, Ruijin Liu, Haitao Liu, Hong Gao, Kaijiang Yu, Changsong Wang,

BACKGROUND:This study aims to explore the mechanism of immunosuppression in septic Acute Renal Injury (AKI) and the role of programmed death-1 (PD-1/PD-L1) pathway in septic AKI. METHODS:This study established a septic AKI model by Cecal ligation and puncture (CLP) in C57/B6 mice, ELISA was used to test the level of ... Read more >>

J Microbiol Immunol Infect (Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi)
[2019, :]

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Corrigendum: Hybrid Indicators for Fast and Sensitive Voltage Imaging.

Yongxian Xu, Luxin Peng, Sicong Wang, Anqi Wang, Ruirui Ma, Ying Zhou, Jiahe Yang, De-En Sun, Wei Lin, Xing Chen, Peng Zou,

Angew. Chem. Int. Ed. Engl. (Angewandte Chemie (International ed. in English))
[2019, 58(43):15183]

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Controlled modelling of human epiblast and amnion development using stem cells.

Yi Zheng, Xufeng Xue, Yue Shao, Sicong Wang, Sajedeh Nasr Esfahani, Zida Li, Jonathon M Muncie, Johnathon N Lakins, Valerie M Weaver, Deborah L Gumucio, Jianping Fu,

Early human embryonic development involves extensive lineage diversification, cell-fate specification and tissue patterning1. Despite its basic and clinical importance, early human embryonic development remains relatively unexplained owing to interspecies divergence2,3 and limited accessibility to human embryo samples. Here we report that human pluripotent stem cells (hPSCs) in a microfluidic device ... Read more >>

Nature (Nature)
[2019, 573(7774):421-425]

Cited: 8 times

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TREM2 regulates obesity-induced insulin resistance via adipose tissue remodeling in mice of high-fat feeding.

Can Liu, Pinhao Li, Hui Li, Sicong Wang, Lifeng Ding, Hanbin Wang, Hui Ye, Yue Jin, Jinchao Hou, Xiangming Fang, Qiang Shu,

BACKGROUND:Adipose tissue remodeling plays a significant role in obesity-induced insulin resistance. Published studies reported that level of trigger receptor expressed on myeloid cells 2 (TREM2) in adipose tissue is up-regulated in animal models of obesity. This study aims to investigate whether TREM2 regulates obesity-induced insulin resistance via modulating adipose tissue ... Read more >>

J Transl Med (Journal of translational medicine)
[2019, 17(1):300]

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An Improved Metal-to-Ligand Charge Transfer Mechanism for Photocatalytic Hydrogen Evolution.

Sicong Wang, Chao Shen, Yanqi Xu, Yunhao Zhong, Chengyin Wang, Shengyang Yang, Guoxiu Wang,

It is of great significance to fabricate a full-spectrum-active photocatalysts for more efficient utilization of solar energy. An improved metal-to-ligand charge transfer (MLCT) mechanism is proposed for a photocatalyst based on graphitic carbon nitride (g-C3 N4 ). UV/Vis spectroscopy indicates that the as-prepared photocatalyst absorbs light at λ<1100 nm. The rather ... Read more >>

ChemSusChem (ChemSusChem)
[2019, 12(18):4221-4228]

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Clinical-radiomics nomograms for pre-operative differentiation of sacral chordoma and sacral giant cell tumor based on 3D computed tomography and multiparametric magnetic resonance imaging.

Ping Yin, Ning Mao, Sicong Wang, Chao Sun, Nan Hong,

OBJECTIVE:To develop and validate clinical-radiomics nomograms based on three-dimensional CT and multiparametric MRI (mpMRI) for pre-operative differentiation of sacral chordoma (SC) and sacral giant cell tumor (SGCT). METHODS:A total of 83 SC and 54 SGCT patients diagnosed through surgical pathology were retrospectively analyzed. We built six models based on CT, ... Read more >>

Br J Radiol (The British journal of radiology)
[2019, 92(1101):20190155]

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Can clinical radiomics nomogram based on 3D multiparametric MRI features and clinical characteristics estimate early recurrence of pelvic chondrosarcoma?

Ping Yin, Ning Mao, Xia Liu, Chao Sun, Sicong Wang, Lei Chen, Nan Hong,

BACKGROUND:Chondrosarcoma (CS) is the second most common primary malignant bone tumor, with a relatively high recurrence rate. However, an effective method that estimates whether pelvic CS will recur after surgery, which influences the formulation of a clinical treatment plan, remains lacking. PURPOSE:To develop and validate a clinical radiomics nomograms based ... Read more >>

J Magn Reson Imaging (Journal of magnetic resonance imaging : JMRI)
[2020, 51(2):435-445]

Cited: 2 times

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Analyzing Electroencephalography (EEG) Waves Provides a Reliable Tool to Assess the Depth of Sevoflurane Anesthesia in Pediatric Patients.

Deepti Beekoo, Kaiming Yuan, Shuyang Dai, Lifen Chen, Meiqin Di, Sicong Wang, Huacheng Liu, Wangning ShangGuan,

BACKGROUND Studies have reported that BIS is unreliable in children because its algorithm provides misleading information about the actual depth of anesthesia. Raw EEG analysis provides direct neurophysiologic measurement of cerebral activity. The relationship between age and EEG has rarely been reported, thus the aim of the present study was ... Read more >>

Med Sci Monit (Medical science monitor : international medical journal of experimental and clinical research)
[2019, 25:4035-4040]

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Effect of splenectomy on attenuation of LPS-induced AKI through GTS-21-induced cholinergic anti-inflammatory pathway.

Yang Gao, Kai Kang, Xinyu Zhang, Qiuyuan Han, Haitao Liu, Weilan Kong, Xing Zhang, Rui Huang, Zhenyu Yang, Zhidong Qi, Junbo Zheng, Ming Li, Jiayu Li, Ruijin Liu, Yansong Liu, Sicong Wang, Weihua Zhang, Hongliang Wang, Kaijiang Yu,

This work was undertaken to explore the role of splenectomy on attenuation of lipopolysaccharide (LPS)-induced acute kidney injury (AKI) through GTS-21-induced cholinergic anti-inflammatory pathway. C57BL/6 mice were used to construct models of sepsis-induced renal injury. HE, Tunel and blood assays were used to determine the success of the model. The ... Read more >>

(American journal of translational research)
[2019, 11(4):2540-2549]

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Three-dimensional magnetization needle arrays with controllable orientation.

Jianjun Luo, Henwen Zhang, Sicong Wang, Liu Shi, Zhuqing Zhu, Bing Gu, Xiaolei Wang, Xiangping Li,

Based on the Richards-Wolf vectorial diffraction theory and inverse Faraday effect, we first propose a scheme to generate three-dimensional magnetization needle (MN) arrays with arbitrary orientation for each individual needle and controllable spatial position and number by reversing the electric dipole array radiation. To achieve this, each unit of the ... Read more >>

Opt Lett (Optics letters)
[2019, 44(4):727-730]

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Risk factors for outcomes of acute respiratory distress syndrome patients: a retrospective study.

Qingqing Dai, Sicong Wang, Ruijin Liu, Hongliang Wang, Junbo Zheng, Kaijiang Yu,

Background:The determination of risk factors for acute respiratory distress syndrome (ARDS) patients remains a challenge. Our study aims to explore the epidemiology and risk factors affecting outcomes of ARDS patients and provide a theoretical basis for patients' prognosis. Methods:This retrospective study included 207 ARDS patients admitted to the general intensive ... Read more >>

(Journal of thoracic disease)
[2019, 11(3):673-685]

Cited: 1 time

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Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice.

Spencer M Moore, Jason S Seidman, Jacob Ellegood, Richard Gao, Alex Savchenko, Ty D Troutman, Yohei Abe, Josh Stender, Daehoon Lee, Sicong Wang, Bradley Voytek, Jason P Lerch, Hoonkyo Suh, Christopher K Glass, Alysson R Muotri,

SETD5, a gene linked to intellectual disability (ID) and autism spectrum disorder (ASD), is a member of the SET-domain family and encodes a putative histone methyltransferase (HMT). To date, the mechanism by which SETD5 haploinsufficiency causes ASD/ID remains an unanswered question. Setd5 is the highly conserved mouse homolog, and although ... Read more >>

Transl Psychiatry (Translational psychiatry)
[2019, 9(1):24]

Cited: 4 times

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All-optical generation of magnetization with arbitrary three-dimensional orientations.

Sicong Wang, Jianjun Luo, Zhuqing Zhu, Yaoyu Cao, Haiwei Wang, Changsheng Xie, Xiangping Li,

In this Letter, all-optical generation of magnetization with arbitrary three-dimensional (3D) orientations is numerically demonstrated through the inverse Faraday effect (IFE) by using a reversing calculation method. The IFE-induced magnetization with an expected 3D orientation is initially conceived by coherently configuring two orthogonally arranged electric dipoles with a phase difference ... Read more >>

Opt Lett (Optics letters)
[2018, 43(22):5551-5554]

Cited: 1 time

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Dopamine D1 Receptor Within Basolateral Amygdala Is Involved in Propofol Relapse Behavior Induced by Cues.

Sicong Wang, Xin Wang, Wenxuan Lin, Suhao Bao, Benfu Wang, Binbin Wu, Ying Su, Qingquan Lian,

Propofol has been proven to be potentially abused by humans and laboratory animals; however, studies that have examined propofol relapse behavior are limited, and its underlying mechanism remains unclear. In this study, we examined whether basolateral amygdala-specific or systematic administration of the dopamine receptor antagonist alters cue-induced propofol-seeking behaviors in ... Read more >>

Neurochem. Res. (Neurochemical research)
[2018, 43(12):2393-2403]

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African Trypanosomiasis (Sleeping Sickness)

Noel Dunn, Sicong Wang, Rotimi Adigun,

African trypanosomiasis, also known as human African trypanosomiasis (HAT) and sleeping sickness, is caused by 1 of 2 Trypanosoma brucei protozoa transmitted by the tsetse fly in sub-Saharan Africa. The disease is considered a neglected tropical disease and remains a nearly universal fatal disease if not treated.[1][2][3] ... Read more >>

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Theoretical study on host-guest interaction between pillar[4]arene and molecules or ions.

Chao Shen, Zhenyu Gong, Lei Gao, Minglong Gu, Long Huan, Sicong Wang, Ju Xie,

In order to systematically explore the general rule of the host-guest chemistry for pillararenes, this work investigates the weak interactions between pillar[4]arene and some typical guests (anions, cations, and dumbbell-shaped molecules) by using density functional theory (DFT) calculations at the ωB97XD/6-311G(d,p) level. The strong molecular recognition ability of pillar[4]arene has ... Read more >>

J Mol Model (Journal of molecular modeling)
[2018, 24(8):199]

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Contribution of the α5 GABAA receptor to the discriminative stimulus effects of propofol in rat.

Benfu Wang, Kun Lv, Huifeng Liu, Yin Su, Hong Wang, Sicong Wang, Suhao Bao, Wen-Hua Zhou, Qing-Quan Lian,

Propofol as an agonist of GABAA receptor has a rewarding and discriminative stimulus effect. However, which subtype of the GABAA receptor is involved in the discriminative stimulus effects of propofol is still not clear. We observed the effects of an agonist or an antagonist of the subtype-selective GABAA receptor on ... Read more >>

Neuroreport (Neuroreport)
[2018, 29(5):347-352]

Cited: 1 time

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Stable and Efficient Nitrogen-Containing Carbon-Based Electrocatalysts for Reactions in Energy-Conversion Systems.

Sicong Wang, Zhengyuan Teng, Chengyin Wang, Guoxiu Wang,

High activity and stability are crucial for the practical use of electrocatalysts in fuel cells, metal-air batteries, and water electrolysis, including the oxygen reduction reaction, hydrogen evolution reaction, oxygen evolution reaction, and oxidation reactions of formic acid and alcohols. Electrocatalysts based on nitrogen-containing carbon (N-C) materials show promise in catalyzing ... Read more >>

ChemSusChem (ChemSusChem)
[2018, 11(14):2267-2295]

Cited: 1 time

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