Full Text Journal Articles by
Author Shuai Yu

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HOTTIP downregulation reduces neuronal damage and microglial activation in Parkinson's disease cell and mouse models.

Peng Lun, Tao Ji, De-Hong Wan, Xia Liu, Xiao-Dong Chen, Shuai Yu, Peng Sun,

HOXA transcript at the distal tip (HOTTIP), a newly identified long noncoding RNA, has been shown to exhibit anti-inflammatory effects and inhibit oxygen-glucose deprivation-induced neuronal apoptosis. However, its role in Parkinson's disease (PD) remains unclear. 1-Methyl-4-phenylpyridium (MPP<sup>+</sup>) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were used to establish PD models in SH-SY5Y and BV2 ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(4):887-897]

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AXIN2 reduces the survival of porcine induced pluripotent stem cells (piPSCs)

rui zhang, Shuai Yu, Qiaoyan Shen, Wenxu Zhao, Juqing Zhang, Xiaolong Wu, Zhenshuo Zhu, Xiaojie Wu, Na Li, Sha Peng, Jinlian Hua,

<h4>Background: </h4> The establishment of porcine pluripotent stem cells (piPSCs) is still a critical topic and challenging issue. However, all piPSCs are extremely sensitive to changes of the culture conditions.In addition, the side effect of inhibitors in culture medium confine the pluripotency and practicability. This study aimed to investigate the ... Read more >>

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Evaluating Water-Yield Property of Karst Aquifer Based On The AHP And CV

Shuai Yu, Hanghang Ding, Yifan Zeng,

In order to ensure the safety of mine production, it is of great practical significance to make a reasonable evaluation of the water-yield property (WYP) of a karst aquifer. In this paper, we selected fault-lines distribution, fault-scale index, aquifer thickness, water pressure, consumption of rinsing liquid, and hydraulic conductivity as ... Read more >>

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Identification of key molecular markers in epithelial ovarian cancer by integrated bioinformatics analysis.

Wenqiong Qin, Qiang Yuan, Yi Liu, Ying Zeng, Dandan Ke, Xiaoyan Dai, Yu Shuai, Jiaqi Hu, Hua Shi,

<h4>Objective</h4>The current research was aimed to identify candidate genes associated with development and progression of epithelial ovarian carcinoma using bioinformatics analysis.<h4>Materials and methods</h4>We screened and validated candidate genes associated with carcinogenesis and development of epithelial ovarian carcinoma via bioinformatic analysis in three microarray datasets (GSE14407, GSE29450, and GSE54388) downloaded from ... Read more >>

Taiwan J Obstet Gynecol (Taiwanese journal of obstetrics & gynecology)
[2021, 60(6):983-994]

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The Efficacy and Safety of Infliximab in Refractory Noninfectious Uveitis: A Meta-Analysis of Observational Studies.

Anji Xiong, Deng Liu, Huini Chen, Guancui Yang, Chen Xiong, Yu Shuai, Linqian He, Zepeng Guo, Liangwen Zhang, Yuan Yang, Beibei Cui, Shiquan Shuai,

<b>Background:</b> Although infliximab has been recommended for the second-line treatment of seronegative spondyloarthropathy- or juvenile idiopathic arthritis-related uveitis, the issue of its systemic efficacy and safety in a broader diversity of refractory noninfectious uveitis is debatable. To assess the short-term and relatively long-term efficacy of infliximab in refractory noninfectious uveitis, ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2021, 12:620340]

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Nucleoporin 50 mediates Kcna4 transcription to regulate cardiac electrical activity.

Xueting Gao, Shuai Yu, Yi Guan, Yunli Shen, Liang Xu,

Emerging evidence has demonstrated that nucleoporins (Nups) play a pivotal role in cell-type-specific gene regulation, but how they control the expression and activity of ion channel genes in the heart remains unclear. Here, we show that Nup50, which is localized in the nucleus of cardiomyocytes, selectively induces an increase in ... Read more >>

J Cell Sci (Journal of cell science)
[2021, 134(18):]

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Machine learning analysis of multispectral imaging and clinical risk factors to predict amputation wound healing.

John J Squiers, Jeffrey E Thatcher, David Bastawros, Andrew J Applewhite, Ronald D Baxter, Faliu Yi, Peiran Quan, Shuai Yu, J Michael DiMaio, Dennis R Gable,

<h4>Objective</h4>Prediction of amputation wound healing is challenging due to the multifactorial nature of critical limb ischemia and lack of objective assessment tools. Up to one-third of amputations require revision to a more proximal level within 1 year. We tested a novel wound imaging system to predict amputation wound healing at initial ... Read more >>

J Vasc Surg (Journal of vascular surgery)
[2021, :]

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Chestnut Polysaccharides Rescue Impaired Spermatogenesis by Adjusting Gut Microbiota

Zhong-Yi Sun, Shuai Yu, Yu Tian, Bao-Quan Han, Yong Zhao, Ya-Qi Li, Yan Wang, Yu-Jiang Sun, Wei Shen,

<h4>Background: </h4> Our previous study confirmed the beneficial effects of chestnut polysaccharides on the spermatogenesis process, but the exact mechanism is not clear. Several studies have demonstrated the importance of a balanced gut microbiota in maintaining normal reproductive function. In this study, we investigated the biological functions of chestnut polysaccharides ... Read more >>

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A two-stage amplified PZT sensor for monitoring lung and heart sounds in discharged pneumonia patients.

Hongbin Chen, Shuai Yu, Haiyang Liu, Jie Liu, Yongguang Xiao, Dandan Wu, Xiaoyu Pan, Cuihong Zhou, Yifeng Lei, Sheng Liu,

Assessment of lung and heart states is of critical importance for patients with pneumonia. In this study, we present a small-sized and ultrasensitive accelerometer for continuous monitoring of lung and heart sounds to evaluate the lung and heart states of patients. Based on two-stage amplification, which consists of an asymmetric ... Read more >>

Microsyst Nanoeng (Microsystems & nanoengineering)
[2021, 7:55]

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Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack.

Zhiliang Guo, Guoli Xu, Ruojun Wang, Jie Hou, Shuhong Yu, Huaishun Wang, Shuai Yu, Jiaping Xu, Shoujiang You, Zhichao Huang, Guodong Xiao, Yongjun Cao, Chun-Feng Liu,

<h4>Objective</h4>Thyroid dysfunction is associated with an elevated risk of cognitive decline, but the mechanism underlying this relationship is elusive. In this study, we investigate the relationships between free thyroxine (FT4), brain frailty and clock drawing test (CDT) performance in patients with acute minor stroke or transient ischaemic attack (TIA).<h4>Design, patients and ... Read more >>

Clin Endocrinol (Oxf) (Clinical endocrinology)
[2021, :]

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Histone demethylase complexes KDM3A and KDM3B cooperate with OCT4/SOX2 to define a pluripotency gene regulatory network.

Zhenshuo Zhu, Xiaolong Wu, Qun Li, Juqing Zhang, Shuai Yu, Qiaoyan Shen, Zhe Zhou, Qin Pan, Wei Yue, Dezhe Qin, Ying Zhang, Wenxu Zhao, Rui Zhang, Sha Peng, Na Li, Shiqiang Zhang, Anmin Lei, Yi-Liang Miao, Zhonghua Liu, Xingqi Chen, Huayan Wang, Mingzhi Liao, Jinlian Hua,

The pluripotency gene regulatory network of porcine induced pluripotent stem cells(piPSCs), especially in epigenetics, remains elusive. To determine the biological function of epigenetics, we cultured piPSCs in different culture conditions. We found that activation of pluripotent gene- and pluripotency-related pathways requires the erasure of H3K9 methylation modification which was further ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(6):e21664]

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Label-free quantitative proteomics analysis of Humulus scandens (Lour.) Merr. leaves treated by an odor compound of Periploca sepium Bunge.

Xiaxia Wang, Dinglei Xiang, Ziyi Wang, Zhaoguo Wang, Xue Yang, Shuai Yu, Qiuxia Pang, Sheng Liu, Li Yan,

The odor compound from Periploca sepium Bunge, 2-hydroxy-4-methoxy-benzaldehyde (HMB), is an allelochemical agent and is one of the least investigated isomers of vanillin. In this study, we used label-free quantitative proteomics analysis technology to investigate the effect of HMB on the protein expression of Humulus scandens (Lour.) Merr. leaves in ... Read more >>

Ecotoxicol Environ Saf (Ecotoxicology and environmental safety)
[2021, 215:112131]

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One potential biomarker for teratozoospermia identified by in-depth integrative analysis of multiple microarray data.

Baoquan Han, Lu Wang, Shuai Yu, Wei Ge, Yaqi Li, Hui Jiang, Wei Shen, Zhongyi Sun,

Teratozoospermia is a common category of male infertility and with the increase in clinical patients and the increasing sophistication of assisted reproductive technology, there is an urgent need for an accurate semen diagnostic biomarker to accomplish rapid diagnosis of patients with teratozoospermia and accurately assess the success rate of assisted ... Read more >>

Aging (Albany NY) (Aging)
[2021, 13(7):10208-10224]

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The Role of Mycophenolate Mofetil for the Induction of Remission in ANCA-Associated Vasculitis: A Meta-Analysis.

Anji Xiong, Chen Xiong, Guancui Yang, Yu Shuai, Deng Liu, Linqian He, Zepeng Guo, Liangwen Zhang, Yi Liu, Yuan Yang, Beibei Cui, Shiquan Shuai,

<b>Objectives:</b> The successful introduction of mycophenolate mofetil (MMF) as a treatment for renal allograft reduced the incidence of acute rejection. The inspiring effects obtained by the MMF have led to an evaluation of its therapeutic potency on ANCA-associated vasculitis (AAV). However, there is little evidence of the MMF's efficacy on ... Read more >>

Front Med (Lausanne) (Frontiers in medicine)
[2021, 8:609924]

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Comparison of three species of Elizabethkingia genus by whole-genome sequence analysis.

Chen Yang, Zhe Liu, Shuai Yu, Kun Ye, Xin Li, Dingxia Shen,

Elizabethkingia are found to cause severe neonatal meningitis, nosocomial pneumonia, endocarditis and bacteremia. However, there are few studies on Elizabethkingia genus by comparative genomic analysis. In this study, three species of Elizabethkingia were found: E. meningoseptica, E. anophelis and E. miricola. Resistance genes and associated proteins of seven classes of ... Read more >>

FEMS Microbiol Lett (FEMS microbiology letters)
[2021, 368(5):]

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Dexmedetomidine-soaked nasal packing can reduce pain and improve sleep quality after nasal endoscopic surgery: a double-blind, randomized, controlled clinical trial.

Yuting Wang, Yu Shuai, Fudan Qiu, Jiamei He, Shaohui Zhuang,

<h4>Study objective</h4>Bilateral endoscopic nasal surgery is usually associated with pain and sleep disturbance. The aim of this study was to evaluate the effects of dexmedetomidine-soaked nasal packing on analgesia and improvement of sleep quality in patients undergoing this surgery.<h4>Method</h4>Eighty patients were enrolled and randomly allocated into 4 groups. At the ... Read more >>

Sleep Breath (Sleep & breathing = Schlaf & Atmung)
[2021, 25(4):2045-2052]

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CDCA8 as an independent predictor for a poor prognosis in liver cancer.

Yu Shuai, Erxi Fan, Qiuyue Zhong, Qiying Chen, Guangyong Feng, Xiaoxia Gou, Guihai Zhang,

<h4>Background</h4>Human cell division cycle associated 8 (CDCA8) a key regulator of mitosis, has been described as a potential prognostic biomarker for a variety of cancers, such as breast, colon and lung cancers. We aimed to evaluate the potential role of CDCA8 expression in the prognosis of liver cancer by analysing ... Read more >>

Cancer Cell Int (Cancer cell international)
[2021, 21(1):159]

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Infertility network and hub genes for nonobstructive azoospermia utilizing integrative analysis.

Baoquan Han, Zihui Yan, Shuai Yu, Wei Ge, Yaqi Li, Yan Wang, Bo Yang, Wei Shen, Hui Jiang, Zhongyi Sun,

Non-obstructive azoospermia (NOA) is the most severe form of male infertility owing to the absence of sperm during ejaculation as a result of failed spermatogenesis. The molecular mechanisms of NOA have not been well studied. Here, we revealed the dysregulated differentially expressed genes in NOA and related signaling pathways or ... Read more >>

Aging (Albany NY) (Aging)
[2021, 13(5):7052-7066]

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Peripheral body temperature rhythm is associated with suicide risk in major depressive disorder: a case-control study.

Xin Ma, Jing Cao, Hailin Zheng, Xinchun Mei, Meijuan Wang, Haoran Wang, Yu Shuai, Yuan Shen,

<h4>Background</h4>Patients with major depressive disorder (MDD) may have an abnormal peripheral body temperature rhythm, but its relationship with suicidal risk and the response to treatment with antidepressants remain unknown.<h4>Aims</h4>This study aimed to investigate the feature of peripheral body temperature in patients with MDD and its relationship with suicide risk before ... Read more >>

Gen Psychiatr (General psychiatry)
[2021, 34(1):e100219]

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Three new species and one newly recorded species of genus Frisilia Walker (Lepidoptera, Lecithoceridae) from China, with a checklist of the world.

Shuai Yu, Shuxia Wang,

Three species of the genus Frisilia Walker, 1864 are described as new: Frisilia basistricta sp. nov., F. motuoensis sp. nov. and F. trisigna sp. nov.; F. sulcata is newly recorded in China. Images of adults and genitalia for all newly described species, a key to the Chinese species, a checklist ... Read more >>

Zootaxa (Zootaxa)
[2021, 4926(1):zootaxa.4926.1.4]

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Purification of hypocrellins from Shiraia bambusicola by coordinated high-speed countercurrent chromatography using cupric chloride as a complexing agent.

Hongjing Dong, Xue Yao, Lanping Guo, Shuai Yu, Wenjuan Duan, Wei Liu, Xiao Wang,

Hypocrellins are anthraquinone that can act as excellent photosensitizers for photodynamic therapy. In the present work, we found that high-speed countercurrent chromatography using cupric chloride as a complexing agent effectively separated hypocrellins from Shiraia bambusicola extract. The optimal two-phase solvent system consisted of petroleum ether/ethyl acetate/methanol/water (7:3:5.5:4.5, v/v/v/v), with 0.01 mol/L ... Read more >>

J Sep Sci (Journal of separation science)
[2021, 44(7):1383-1390]

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[Single Center Analysis of Bloodstream Infection Clinical Characteristics and Prognosis in Patients with Hematological Malignancies in the Tropics].

Long-Can Cheng, Ting Yang, Hui-Hui Kuang, Shuai Yu, Li-Xun Guan, Zhen-Yang Gu, Yuan-Yuan Xu, Wen-Shuai Zheng, Lu Wang, Ya-Lei Hu, Xiao-Ning Gao, Quan-Shun Wang,

<h4>Objective</h4>To analyze the characteristics, prognosis and risk factors of bloodstream infection in patients with hematological malignancies in the tropics, so as to provide evidence for the prevention and treatment of bloodstream infection.<h4>Methods</h4>The clinical features, blood culture results and prognosis of patients with bloodstream infection in patients with hematological malignancies admitted ... Read more >>

Zhongguo Shi Yan Xue Ye Xue Za Zhi (Zhongguo shi yan xue ye xue za zhi)
[2021, 29(1):265-271]

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Electrochemiluminescence ultrasensitive immunoassay for carbohydrate antigen 125 based on AgInS2/ZnS nanocrystals.

Min Yin, Yan Wang, Xuwen Gao, Shichao Du, Yan Cheng, Shuai Yu, Guizheng Zou, Fumin Xue,

We developed a near-infrared (NIR) electrochemiluminescence (ECL) immunosensor for sensitively and selectively determining carbohydrate antigen 125 (CA125) with toxic-element-free and environmental-friendly AgInS<sub>2</sub>/ZnS nanocrystals (NCs) as tags. The core/shell-structured AgInS<sub>2</sub>/ZnS NCs not only can be conveniently prepared via an aqueous synthetic procedure, but also has high photoluminescence quantum yield (PLQY) of ... Read more >>

Anal Bioanal Chem (Analytical and bioanalytical chemistry)
[2021, 413(8):2207-2215]

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Deoxymikanolide adversely altered physiology and ultrastructure of Ralstonia solanacearum.

Yan Li, Yun-Fei Zeng, Zi-Yi Wang, Yan Fan, Xue Yang, Zhaoguo Wang, Shuai Yu, Qiuxia Pang, Ao-Cheng Cao,

Deoxymikanolide (DEO) was isolated from Mikania micrantha Bunge and identified as a novel antibacterial compound previously. However, the mode of antimicrobial mechanism of DEO was not clear but hypothesized to affect the morphology and physiology of Ralstonia solanacearum cells. In this study, we confirmed our hypothesis via transmission electron microscopy ... Read more >>

Pestic Biochem Physiol (Pesticide biochemistry and physiology)
[2021, 174:104803]

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Mir-34c affects the proliferation and pluripotency of porcine induced pluripotent stem cell (piPSC)-like cells by targeting c-Myc.

Wei Yue, Jing Sun, Juqing Zhang, Yongxing Chang, Qiaoyan Shen, Zhenshuo Zhu, Shuai Yu, Xiaolong Wu, Sha Peng, Na Li, Jinlian Hua,

MicroRNAs are important regulators in stem cells, which involve in gene regulation, including cell proliferation, differentiation and apoptosis. As an important one, miR-34c participates in various processes by targeting protein-coding genes. It is generally considered as a tumor suppressor and cell adhesion inhibitor. However, whether miR-34c has effects on pluripotent ... Read more >>

Cells Dev (Cells & development)
[2021, 166:203665]

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