Full Text Journal Articles by
Author Shelley A Boeschoten

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Nontraumatic Myelopathy in Malawi: A Prospective Study in an Area with High HIV Prevalence.

Eduard E Zijlstra, Jaap J van Hellemond, Arthur D Moes, Christa de Boer, Shelley A Boeschoten, Catharina E M van Blijswijk, Roos M van der Vuurst de Vries, Peter A B Bailey, Sam Kampondeni, Lisette van Lieshout, Saskia L Smits, Juri Katchanov, Nyengo M Mkandawire, Camilla Rothe,

Nontraumatic myelopathy causes severe morbidity and is not uncommon in Africa. Clinically, patients often present with paraplegia, and extrinsic cord compression and transverse myelitis are most common causes. Data on exact pathogenesis are scanty because of limitations in diagnostic methods. In Queen Elizabeth Central Hospital, Blantyre, Malawi, we recorded consecutive ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, 102(2):451-457]

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Population Pharmacokinetics of Intravenous Salbutamol in Children with Refractory Status Asthmaticus.

Nienke J Vet, Brenda C M de Winter, Muriel Koninckx, Shelley A Boeschoten, Annemie L M Boehmer, Jacintha T Verhallen, Frans B Plötz, Anja A Vaessen-Verberne, Bart C H van der Nagel, Catherijne A J Knibbe, Corinne M P Buysse, Saskia N de Wildt, Birgit C P Koch, Matthijs de Hoog,

BACKGROUND:Intravenous salbutamol is used to treat children with refractory status asthmaticus, however insufficient pharmacokinetic data are available to guide initial and subsequent dosing recommendations for its intravenous use. The pharmacologic activity of salbutamol resides predominantly in the (R)-enantiomer, with little or no activity and even concerns of adverse reactions attributed ... Read more >>

Clin Pharmacokinet (Clinical pharmacokinetics)
[2020, 59(2):257-264]

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A Loading Dose of IV Salbutamol in an Adolescent with Severe Acute Asthma and Cardiac Arrest.

Shelley A Boeschoten, Ruben S van der Crabben, Annemie L M Boehmer, Matthijs de Hoog, Corinne M P Buysse,

Severe acute asthma (SAA) can lead to respiratory failure and can be fatal. For rational use of intravenous (IV) bronchodilators, evidence regarding the pharmacokinetics and pharmacodynamics is lacking in children. The use of a loading dose IV salbutamol is not mentioned in any international guideline, and its use varies greatly ... Read more >>

Case Rep Pediatr (Case reports in pediatrics)
[2019, 2019:5057390]

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Children with severe acute asthma admitted to Dutch PICUs: A changing landscape.

Shelley A Boeschoten, Corinne M P Buysse, Peter J F M Merkus, Jacob M C van Wijngaarden, Sabien G J Heisterkamp, Johan C de Jongste, Joost van Rosmalen, Suzan C M Cochius-den Otter, Annemie L M Boehmer, Matthijs de Hoog, ,

The number of children requiring pediatric intensive care unit (PICU) admission for severe acute asthma (SAA) around the world has increased. OBJECTIVES:We investigated whether this trend in SAA PICU admissions is present in the Netherlands. METHODS:A multicenter retrospective cohort study across all tertiary care PICUs in the Netherlands. Inclusion criteria ... Read more >>

Pediatr. Pulmonol. (Pediatric pulmonology)
[2018, 53(7):857-865]

Cited: 1 time

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