Full Text Journal Articles by
Author Sheila T Angeles Han

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Uveitis in Children and Adolescents.

Margaret H Chang, Jessica G Shantha, Jacob J Fondriest, Mindy S Lo, Sheila T Angeles-Han,

Childhood noninfectious uveitis leads to sight-threatening complications. Idiopathic chronic anterior uveitis and juvenile idiopathic arthritis-associated uveitis are most common. Inflammation arises from an immune response against antigens within the eye. Ophthalmic work-up evaluates anatomic involvement, disease activity, ocular complications, and disease course. Local and/or systemic glucocorticoids are initial treatment, but ... Read more >>

Rheum Dis Clin North Am (Rheumatic diseases clinics of North America)
[2021, 47(4):619-641]

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Immediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases.

Jonathan S Hausmann, Kevin Kennedy, Julia F Simard, Jean W Liew, Jeffrey A Sparks, Tarin T Moni, Carly Harrison, Maggie J Larché, Mitchell Levine, Sebastian E Sattui, Teresa Semalulu, Gary Foster, Salman Surangiwala, Lehana Thabane, Richard P Beesley, Karen L Durrant, Elsa F Mateus, Serena Mingolla, Michal Nudel, Candace A Palmerlee, Dawn P Richards, David F L Liew, Catherine L Hill, Suleman Bhana, Wendy Costello, Rebecca Grainger, Pedro M Machado, Philip C Robinson, Paul Sufka, Zachary S Wallace, Jinoos Yazdany, Emily Sirotich, ,

<h4>Background</h4>The impact and consequences of the COVID-19 pandemic on people with rheumatic disease are unclear. We developed the COVID-19 Global Rheumatology Alliance Patient Experience Survey to assess the effects of the COVID-19 pandemic on people with rheumatic disease worldwide.<h4>Methods</h4>Survey questions were developed by key stakeholder groups and disseminated worldwide through ... Read more >>

Lancet Rheumatol (The Lancet. Rheumatology)
[2021, 3(10):e707-e714]

Cited: 1 time

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Update on biologic therapies for juvenile idiopathic arthritis-associated uveitis.

Joanne Thomas, Sanjana Kuthyar, Jessica G Shantha, Sheila T Angeles-Han, Steven Yeh,

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood, and juvenile idiopathic associated uveitis (JIA-U) is the most frequently noted extra-articular manifestation. JIA-U can present asymptomatically and lead to ocular complications, so regular screening and monitoring are needed to prevent potentially sight-threatening sequelae. Topical glucocorticoids such as ... Read more >>

Ann Eye Sci (Annals of eye science)
[2021, 6:]

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Prevalence of autoimmune diseases and other associated conditions in children and young adults with juvenile idiopathic arthritis.

Daniel J Lovell, Bin Huang, Chen Chen, Sheila T Angeles-Han, Teresa A Simon, Hermine I Brunner,

<h4>Objective</h4>Many autoimmune diseases share common pathogenic mechanisms; however, there are limited studies quantifying the coexistence of autoimmune diseases and associated conditions in patients with juvenile idiopathic arthritis (JIA). This large US-based study estimated and compared the prevalence of multiple coexisting autoimmune diseases in patients with JIA with a general paediatric ... Read more >>

RMD Open (RMD open)
[2021, 7(1):]

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Comprehensive assessment of quality of life, functioning and mental health in children with juvenile idiopathic arthritis and non-infectious uveitis.

Joseph McDonald, Amy Cassedy, Mekibib Altaye, Jennifer Andringa, Ashley M Cooper, Carolyn Drews-Botsch, George Engelhard, Theresa Hennard, Gary N Holland, Kirsten Jenkins, Scott R Lambert, Jessi Lipscomb, Courtney McCracken, Deborah K McCurdy, Najima Mwase, Sampath Prahalad, Jessica Shantha, Erin Stahl, Virginia Miraldi Utz, A Adrienne Walker, Steven Yeh, Sheila T Angeles-Han,

<h4>Objective</h4>Pediatric uveitis can lead to sight-threatening complications and impact quality of life (QOL) and functioning. We aim to examine health-related QOL (HRQOL), mental health, physical disability, vision-related functioning (VRF), and vision-related QOL (VRQOL) in children with juvenile idiopathic arthritis (JIA), JIA-associated uveitis (JIA-U), and other non-infectious uveitis. We hypothesize that ... Read more >>

Arthritis Care Res (Hoboken) (Arthritis care & research)
[2021, :]

Cited: 1 time

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Assessing the validity and reliability of the Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) questionnaire among children with uveitis.

Amy Cassedy, Mekibib Altaye, Jennifer Andringa, Ashley M Cooper, Carolyn Drews-Botsch, George Engelhard, Theresa Hennard, Gary N Holland, Kirsten Jenkins, Scott R Lambert, Jessi Lipscomb, Courtney McCracken, Deborah K McCurdy, Joseph McDonald, Najima Mwase, Sampath Prahalad, Erin Stahl, Virginia Miraldi Utz, A Adrienne Walker, Steven Yeh, Sheila T Angeles-Han,

<h4>Purpose</h4>The Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) questionnaire measures vision-related functioning (VRF) and vision-related quality of life (VRQOL) in children with uveitis. Our aim was to revise the Alpha version of the EYE-Q to refine VRF and VRQOL subscales and assess the validity of the EYE-Q.<h4>Methods</h4>Children with ... Read more >>

Arthritis Care Res (Hoboken) (Arthritis care & research)
[2020, :]

Cited: 1 time

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Ophthalmology perspectives on the management of juvenile idiopathic arthritis-associated uveitis: Eyeing the need for global, multidisciplinary collaborations.

Sheila T Angeles-Han, Steven Yeh,

Clin Exp Ophthalmol (Clinical & experimental ophthalmology)
[2021, 49(1):12-14]

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Reply.

Sarah Ringold, Suzanne Schrandt, Emily L Creek, Timothy Beukelman, Sheila T Angeles-Han, Daniel J Lovell,

Arthritis Rheumatol (Arthritis & rheumatology (Hoboken, N.J.))
[2020, 72(6):1040-1041]

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Correction to: Proposal for a definition for response to treatment, inactive disease and damage for JIA associated uveitis based on the validation of a uveitis related JIA outcome measures from the Multinational Interdisciplinary Working Group for Uveitis in Childhood (MIWGUC).

Ivan Foeldvari, Jens Klotsche, Gabriele Simonini, Clive Edelsten, Sheila T Angeles-Han, Regitze Bangsgaard, Joke de Boer, Gabriele Brumm, Rosa Bou Torrent, Tamas Constantin, Cinzia DeLibero, Jesus Diaz, Valeria Maria Gerloni, Margarida Guedes, Arnd Heiligenhaus, Kaisu Kotaniemi, Sanna Leinonen, Kirsten Minden, Vasco Miranda, Elisabetta Miserocchi, Susan Nielsen, Martina Niewerth, Irene Pontikaki, Carmen Garcia de Vicuna, Carla Zilhao, Steven Yeh, Jordi Anton,

Following publication of the original article [1], we have been notified that the author Joan Calzada should not have been included to the team of authors. The authors' team, thus, should be as follows. ... Read more >>

Pediatr Rheumatol Online J (Pediatric rheumatology online journal)
[2020, 18(1):14]

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Proposal for a definition for response to treatment, inactive disease and damage for JIA associated uveitis based on the validation of a uveitis related JIA outcome measures from the Multinational Interdisciplinary Working Group for Uveitis in Childhood (MIWGUC).

Ivan Foeldvari, Jens Klotsche, Gabriele Simonini, Clive Edelsten, Sheila T Angeles-Han, Regitze Bangsgaard, Joke de Boer, Gabriele Brumm, Rosa Bou Torrent, Tamas Constantin, Cinzia DeLibero, Jesus Diaz, Valeria Maria Gerloni, Margarida Guedes, Arnd Heiligenhaus, Kaisu Kotaniemi, Sanna Leinonen, Kirsten Minden, Vasco Miranda, Elisabetta Miserocchi, Susan Nielsen, Martina Niewerth, Irene Pontikaki, Carmen Garcia de Vicuna, Carla Zilhao, Steven Yeh, Jordi Anton,

BACKGROUND:JIA-associated uveitis (JIAU) is a serious, sight-threatening disease with significant long-term complications and risk of blindness, even with improved contemporary treatments. The MIWGUC was set up in order to propose specific JIAU activity and response items and to validate their applicability for clinical outcome studies. METHODS:The group consists of 8 ... Read more >>

Pediatr Rheumatol Online J (Pediatric rheumatology online journal)
[2019, 17(1):66]

Cited: 5 times

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2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis.

Sheila T Angeles-Han, Sarah Ringold, Timothy Beukelman, Daniel Lovell, Carlos A Cuello, Mara L Becker, Robert A Colbert, Brian M Feldman, Gary N Holland, Polly J Ferguson, Harry Gewanter, Jaime Guzman, Jennifer Horonjeff, Peter A Nigrovic, Michael J Ombrello, Murray H Passo, Matthew L Stoll, C Egla Rabinovich, H Nida Sen, Rayfel Schneider, Olha Halyabar, Kimberly Hays, Amit Aakash Shah, Nancy Sullivan, Ann Marie Szymanski, Marat Turgunbaev, Amy Turner, James Reston,

<h4>Objective</h4>To develop recommendations for the screening, monitoring, and treatment of uveitis in children with juvenile idiopathic arthritis (JIA).<h4>Methods</h4>Pediatric rheumatologists, ophthalmologists with expertise in uveitis, patient representatives, and methodologists generated key clinical questions to be addressed by this guideline. This was followed by a systematic literature review and rating of the ... Read more >>

Arthritis Care Res (Hoboken) (Arthritis care & research)
[2019, 71(6):703-716]

Cited: 22 times

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2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis.

Sarah Ringold, Sheila T Angeles-Han, Timothy Beukelman, Daniel Lovell, Carlos A Cuello, Mara L Becker, Robert A Colbert, Brian M Feldman, Polly J Ferguson, Harry Gewanter, Jaime Guzman, Jennifer Horonjeff, Peter A Nigrovic, Michael J Ombrello, Murray H Passo, Matthew L Stoll, C Egla Rabinovich, Rayfel Schneider, Olha Halyabar, Kimberly Hays, Amit Aakash Shah, Nancy Sullivan, Ann Marie Szymanski, Marat Turgunbaev, Amy Turner, James Reston,

<h4>Objective</h4>To develop treatment recommendations for children with juvenile idiopathic arthritis manifesting as non-systemic polyarthritis, sacroiliitis, or enthesitis.<h4>Methods</h4>The Patient/Population, Intervention, Comparison, and Outcomes (PICO) questions were developed and refined by members of the guideline development teams. A systematic review was conducted to compile evidence for the benefits and harms associated with ... Read more >>

Arthritis Rheumatol (Arthritis & rheumatology (Hoboken, N.J.))
[2019, 71(6):846-863]

Cited: 13 times

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Timing of infliximab and adalimumab initiation despite methotrexate in children with chronic non-infectious anterior uveitis.

Courtney McCracken, Steven Yeh, Kirsten Jenkins, Curtis Travers, Daneka Stryker, Steven Tommasello, Kelly A Rouster-Stevens, Scott R Lambert, Sampath Prahalad, Carolyn Drews-Botsch, Sheila T Angeles-Han,

<h4>Aims</h4>Methotrexate (MTX) is standard treatment in pediatric chronic anterior uveitis (CAU). Addition of tumor necrosis factor-α inhibitors (TNFi) is often needed. We describe the timing and risk factors for TNFi use in children with CAU on MTX.<h4>Methods</h4>In this retrospective study, we reviewed 51 records, and 46 met inclusion criteria. Primary outcome ... Read more >>

Eye (Lond) (Eye (London, England))
[2019, 33(4):629-639]

Cited: 1 time

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2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis.

Sarah Ringold, Sheila T Angeles-Han, Timothy Beukelman, Daniel Lovell, Carlos A Cuello, Mara L Becker, Robert A Colbert, Brian M Feldman, Polly J Ferguson, Harry Gewanter, Jaime Guzman, Jennifer Horonjeff, Peter A Nigrovic, Michael J Ombrello, Murray H Passo, Matthew L Stoll, C Egla Rabinovich, Rayfel Schneider, Olha Halyabar, Kimberly Hays, Amit Aakash Shah, Nancy Sullivan, Ann Marie Szymanski, Marat Turgunbaev, Amy Turner, James Reston,

<h4>Objective</h4>To develop treatment recommendations for children with juvenile idiopathic arthritis manifesting as non-systemic polyarthritis, sacroiliitis, or enthesitis.<h4>Methods</h4>The Patient/Population, Intervention, Comparison, and Outcomes (PICO) questions were developed and refined by members of the guideline development teams. A systematic review was conducted to compile evidence for the benefits and harms associated with ... Read more >>

Arthritis Care Res (Hoboken) (Arthritis care & research)
[2019, 71(6):717-734]

Cited: 18 times

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2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis.

Sheila T Angeles-Han, Sarah Ringold, Timothy Beukelman, Daniel Lovell, Carlos A Cuello, Mara L Becker, Robert A Colbert, Brian M Feldman, Gary N Holland, Polly J Ferguson, Harry Gewanter, Jaime Guzman, Jennifer Horonjeff, Peter A Nigrovic, Michael J Ombrello, Murray H Passo, Matthew L Stoll, C Egla Rabinovich, H Nida Sen, Rayfel Schneider, Olha Halyabar, Kimberly Hays, Amit Aakash Shah, Nancy Sullivan, Ann Marie Szymanski, Marat Turgunbaev, Amy Turner, James Reston,

<h4>Objective</h4>To develop recommendations for the screening, monitoring, and treatment of uveitis in children with juvenile idiopathic arthritis (JIA).<h4>Methods</h4>Pediatric rheumatologists, ophthalmologists with expertise in uveitis, patient representatives, and methodologists generated key clinical questions to be addressed by this guideline. This was followed by a systematic literature review and rating of the ... Read more >>

Arthritis Rheumatol (Arthritis & rheumatology (Hoboken, N.J.))
[2019, 71(6):864-877]

Cited: 6 times

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Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans for Juvenile Idiopathic Arthritis-Associated and Idiopathic Chronic Anterior Uveitis.

Sheila T Angeles-Han, Mindy S Lo, Lauren A Henderson, Melissa A Lerman, Leslie Abramson, Ashley M Cooper, Miriam F Parsa, Lawrence S Zemel, Tova Ronis, Timothy Beukelman, Erika Cox, H Nida Sen, Gary N Holland, Hermine I Brunner, Andrew Lasky, C Egla Rabinovich, ,

OBJECTIVE:Systemic immunosuppressive treatment of pediatric chronic anterior uveitis (CAU), both juvenile idiopathic arthritis-associated and idiopathic anterior uveitis, varies, making it difficult to identify best treatments. The Childhood Arthritis and Rheumatology Research Alliance (CARRA) developed consensus treatment plans (CTPs) for CAU for the purpose of reducing practice variability and allowing future ... Read more >>

Arthritis Care Res (Hoboken) (Arthritis care & research)
[2019, 71(4):482-491]

Cited: 13 times

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Temporomandibular joint involvement in children with juvenile idiopathic arthritis: a preliminary report.

Shelly Abramowicz, Joshua M Levy, Sampath Prahalad, Curtis D Travers, Sheila T Angeles-Han,

OBJECTIVE:Children with juvenile idiopathic arthritis (JIA) are at risk for temporomandibular joint (TMJ) arthritis. This can lead to pain, limited mouth opening, facial asymmetry, and malocclusion. Our objective was to characterize patients with JIA and TMJ involvement in a single center. STUDY DESIGN:This was a retrospective study of children with ... Read more >>

Oral Surg Oral Med Oral Pathol Oral Radiol (Oral surgery, oral medicine, oral pathology and oral radiology)
[2019, 127(1):19-23]

Cited: 2 times

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Yoga Intervention for an Adolescent With Juvenile Idiopathic Arthritis: A Case Study.

Amanda B Feinstein, Lindsey L Cohen, Akihiko Masuda, Anya T Griffin, Kaitlyn L Gamwell, Mukunda T Stiles, Sheila T Angeles-Han, Sampath Prahalad,

Juvenile idiopathic arthritis (JIA) is a chronic rheumatic disease associated with pain, stiffness, and psychosocial difficulties. The purpose of this case study was to investigate the impact of a yoga intervention on pain and morning stiffness in an adolescent female with JIA. A secondary aim was to assess the impact ... Read more >>

Adv Mind Body Med (Advances in mind-body medicine)
[2018, 32(1):13-20]

Cited: 2 times

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Discovery of tear biomarkers in children with chronic non-infectious anterior uveitis: a pilot study.

Sheila T Angeles-Han, Steven Yeh, Purnima Patel, Duc Duong, Kirsten Jenkins, Kelly A Rouster-Stevens, Mekibib Altaye, Ndate Fall, Sherry Thornton, Sampath Prahalad, Gary N Holland,

<h4>Background</h4>Biomarkers in easily obtained specimens that accurately predict uveitis in children with juvenile idiopathic arthritis (JIA) are needed. Aqueous humor has been studied for biomarkers, but is not routinely available. We evaluated tears from children with chronic anterior uveitis (CAU) for biomarkers reported in aqueous humor. In this pilot study, ... Read more >>

J Ophthalmic Inflamm Infect (Journal of ophthalmic inflammation and infection)
[2018, 8(1):17]

Cited: 8 times

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Chronic Anterior Uveitis in Children: Psychosocial Challenges for Patients and Their Families.

Delana M Parker, Sheila T Angeles-Han, Annette L Stanton, Gary N Holland,

PURPOSE:To describe issues of concern to children with chronic anterior uveitis; to consider the psychological impact of chronic anterior uveitis on children's lives; and to understand the effect of a child's chronic illness on other family members. DESIGN:Expert commentary. METHODS:Author experiences were supplemented by a review of pertinent medical literature ... Read more >>

Am J Ophthalmol (American journal of ophthalmology)
[2018, 191:xvi-xxiv]

Cited: 1 time

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Barriers and Facilitators of Mentoring for Trainees and Early Career Investigators in Rheumatology Research: Current State, Identification of Needs, and Road Map to an Inter-Institutional Adult Rheumatology Mentoring Program.

Alexis Ogdie, Jeffrey A Sparks, Sheila T Angeles-Han, Kathleen Bush, Flavia V Castelino, Amit Golding, Yihui Jiang, J Michelle Kahlenberg, Alfred H J Kim, Yvonne C Lee, Kirthi Machireddy, Michael J Ombrello, Ami A Shah, Zachary S Wallace, Peter A Nigrovic, Una E Makris, ,

<h4>Objective</h4>To determine perceived barriers and facilitators to effective mentoring for early career rheumatology investigators and to develop a framework for an inter-institutional mentoring program.<h4>Methods</h4>Focus groups or interviews with rheumatology fellows, junior faculty, and mentors were conducted, audiorecorded, and transcribed. Content analysis was performed using NVivo software. Themes were grouped into ... Read more >>

Arthritis Care Res (Hoboken) (Arthritis care & research)
[2018, 70(3):445-453]

Cited: 5 times

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An Update on Treatment of Pediatric Chronic Non-Infectious Uveitis.

Arjun B Sood, Sheila T Angeles-Han,

There are no standardized treatment protocols for pediatric non-infectious uveitis. Topical corticosteroids are the typical first-line agent, although systemic corticosteroids are used in intermediate, posterior and panuveitic uveitis. Corticosteroids are not considered to be long-term therapy due to potential ocular and systemic side effects. In children with severe and/or refractory ... Read more >>

Curr Treatm Opt Rheumatol (Current treatment options in rheumatology)
[2017, 3(1):1-16]

Cited: 8 times

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Uveitis in children.

Sheila T Angeles-Han, Consuelo Egla Rabinovich,

<h4>Purpose of review</h4>The review provides updates on novel risk markers for the development of pediatric inflammatory uveitis and a severe disease course, on treatment of refractory disease, and on the measurement of visual outcomes.<h4>Recent findings</h4>There are several new genetic markers, biomarkers, and clinical factors that may influence a child's uveitis ... Read more >>

Curr Opin Rheumatol (Current opinion in rheumatology)
[2016, 28(5):544-549]

Cited: 6 times

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Familial autoimmunity in the Childhood Arthritis and Rheumatology Research Alliance registry.

Sampath Prahalad, Courtney E McCracken, Lori A Ponder, Sheila T Angeles-Han, Kelly A Rouster Stevens, Larry B Vogler, Carl D Langefeld, Susan D Thompson, ,

<h4>Background</h4>Clinically distinct autoimmune phenotypes share genetic susceptibility factors. We investigated the prevalence of familial autoimmunity among subjects with juvenile idiopathic arthritis (JIA), childhood systemic lupus erythematosus (cSLE) and juvenile dermatomyositis (JDM) in the CARRA Registry, the largest multicenter observational Registry for pediatric rheumatic disease.<h4>Methods</h4>Children with JIA, cSLE and JDM enrolled ... Read more >>

Pediatr Rheumatol Online J (Pediatric rheumatology online journal)
[2016, 14(1):14]

Cited: 9 times

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Medication use in juvenile uveitis patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance Registry.

Lauren A Henderson, David Zurakowski, Sheila T Angeles-Han, Andrew Lasky, C Egla Rabinovich, Mindy S Lo, ,

<h4>Background</h4>There is not yet a commonly accepted, standardized approach in the treatment of juvenile idiopathic uveitis when initial steroid therapy is insufficient. We sought to assess current practice patterns within a large cohort of children with juvenile uveitis.<h4>Methods</h4>This is a cross-sectional cohort study of patients with uveitis enrolled in the ... Read more >>

Pediatr Rheumatol Online J (Pediatric rheumatology online journal)
[2016, 14(1):9]

Cited: 17 times

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